Ngamanye amaxesha thina okanye umntu esimthandayo kufuneka sifumane unyango olukhulu njengokufakelwa i-stem cell ngenxa yesifo esinzima njengomhlaza. Nangona unyango olunjalo luphumelela, ngamanye amaxesha lunokubangela iingxaki ezithile. Namhlanje sithetha ngeyeza elikhethekileyo elinikwa ukunyanga ingxaki enzima kangaka, kodwa engaqhelekanga. Elo liyeza lokugonya elibizwa ngokuba yiDefibrotide.
Yintoni iDefibrotide kwaye isetyenziselwa ntoni?
Ngamafutshane, iDefibrotide yinaliti ekhethekileyo. Isetyenziselwa ukunyanga imeko enzima eyenzeka emva kokufakelwa i-stem cell, ngenxa yokuvaleka kwemithambo yegazi emincinci kakhulu esibindini . Ngokwezonyango, le meko ibizwa ngokuba yiVeno-occlusive Disease (VOD) okanye iSinusoidal Obstruction Syndrome (SOS).
Khawucinge ukuba kukho imithambo yegazi emincinci edlula esibindini sethu. Emva konyango olukhulu njengokufakelwa i-stem cell, ngamanye amaxesha le mithambo yegazi inokuvaleka. Oku kunokuba nefuthe elikhulu ekusebenzeni kwesibindi. Ngelo xesha, iyeza elibizwa ngokuba yiDefibrotide linceda ukuvula kwakhona le mithambo yegazi ivalekileyo kwaye linciphise umonakalo esibindini.
Into ebalulekileyo kukuba, eli asiloyeza onokulithatha ekhaya. Linikwa njenge-infusion esibhedlele, phantsi kweliso elipheleleyo loogqirha nabahlengikazi .
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Ngaphambi kokuba wena okanye isigulana sakho niqale unyango ngeDefibrotide, kubaluleke kakhulu ukuxelela ugqirha wakho ngembali yakho epheleleyo yempilo. Ngokukodwa, kufuneka uqaphele le miqathango ilandelayo:
| Imeko ekufuneka uyixele | Kutheni kunjalo? |
|---|---|
| Ukuba unesifo sokopha. | Oku kubaluleke kakhulu ukuba sele unayo imeko, njengoko i-defibrotide inokunyusa umngcipheko wokopha. |
| Ukuba uthatha amanye amayeza anciphisa igazi okanye athintela ukujiya kwegazi (izinto ezinciphisa igazi). | Ugqirha ufanele azi oku, kuba ukusebenzisa la mayeza kunye kunokubangela ukopha kakhulu. |
| Ukuba une-allergy kwi-Defibrotide okanye naliphi na elinye iyeza, ukutya, okanye idayi. | Oku kubalulekile ukuthintela iimpembelelo ze-allergy. |
| Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa. | Ufanele uxoxe nogqirha wakho ngendlela eli yeza eliza kumchaphazela ngayo umama nomntwana. |
Amayeza angafanele asetyenziswe kunye neDefibrotide
Isilumkiso: Xa usebenzisa iDefibrotide, amanye amayeza athintela ukujiya kwegazi okanye ukunciphisa igazi, njengeHeparin kunye neAlteplase , anokubangela ukopha kakhulu . Ngoko ke, qiniseka ukuba uxelela ugqirha wakho ngawo onke amayeza owasebenzisayo, kuquka amayeza esintu, iivithamini kunye nezongezo.
Iziphumo ebezingalindelekanga ezinokubakho
Njengayo nayiphi na imithi, iDefibrotide inokubangela ezinye iziphumo ebezingalindelekanga. Ezinye zezi zinokuba yingozi, ngoko ke kubalulekile ukuba uzazi kwaye wazise iqela lakho lezonyango ngokukhawuleza ukuba ufumana naziphi na iimpawu.
| Imiphumela | Ingcaciso |
|---|---|
| Ukuba unale mpawu, xelela ugqirha wakho okanye umongikazi wakho ngokukhawuleza. | |
| Iimpendulo ze-Allergic | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Iimpawu Zokopha | Igazi elikwisitulo okanye indle emnyama, umchamo obomvu okanye omdaka, ukuhlanza into efana nekofu egayiweyo, amabala abomvu eluswini, ukopha okungaqhelekanga emehlweni, kwiintsini, okanye empumlweni. |
| Iimpawu zoxinzelelo lwegazi oluphantsi | Ukuba nesiyezi, ukubona izinto zingacacanga, ukuquleka, ukuziva udiniwe okanye ubuthathaka ngendlela engaqhelekanga. |
| Iimpawu zosulelo | Umkhuhlane okanye ukuziva ubanda, ukukhohlela, umphimbo obuhlungu. |
| Ezi zihlandlo azibalulekanga kangako, kodwa ukuba ziyaqhubeka, xelela ugqirha wakho. | |
| Urhudo | Ukuqunjelwa. |
| Isicaphucaphu | Ukuziva ngathi uhlanza. |
| Ukuhlanza | Ukuhlanza. |
Yintoni omawuyenze ukuba idosi iyanda (i-overdose)?
Ekubeni eli yeza linikwa esibhedlele, phantsi kweliso lezonyango, ngomlinganiselo ochanekileyo, amathuba okuba lisetyenziswe ngokugqithisileyo aphantsi kakhulu. Iqela lezonyango lihlala lixhalabile ngaloo nto. Kodwa ukuba kukho ukurhanelwa kwento enjalo, ugqirha okanye umongikazi esibhedlele uya kuthatha amanyathelo afunekayo. Ngokwesiqhelo, indawo esemthethweni yokufumana ingcebiso kwilizwe lethu xa kukho nayiphi na ityhefu yiZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo . Kodwa xa kukho into efana nale eyenzeka esibhedlele, iYunithi yoNyango oluNgxamisekileyo (i-ETU) yesibhedlele iyavulwa ngoko nangoko.
Umyalezo Wokuya Ekhaya
- I-Defibrotide yinaliti ekhethekileyo enikwa emthanjeni enyanga iingxaki ezinkulu zesibindi ezinokwenzeka emva kokufakelwa iseli yesiqu.
- Kubalulekile ukuxelela ugqirha wakho malunga nazo zonke ezinye iindlela ozisebenzisayo, ingakumbi amayeza okunciphisa igazi, kunye nazo zonke iimeko zempilo onazo.
- Umngcipheko ophambili ngeli xesha lonyango kukopha . Ngoko ke, ukuba ubona nophawu oluncinci lokopha, yazisa iqela lezonyango ngoko nangoko.
- Eli yeza linikwa esibhedlele kuphela kwaye aliloyeza lokusetyenziswa ekhaya.
- Ukuba unemibuzo okanye iinkxalabo malunga nale mithi okanye unyango, nceda ungathandabuzi ukubuza ugqirha wakho okanye abasebenzi bakho bonyango.
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