Ngaba uziva ngathi umqala wakho uyaqina okanye unengxaki yokuginya ukutya xa usitya? Ngamanye amaxesha kwenzeka xa sisitya ngokukhawuleza. Kodwa ukuba ufumana oku kungakhululeki rhoqo, akuqhelekanga. Kusenokuba kukho isizathu sezonyango emva koko. Namhlanje sithetha nge-Eosinophilic Esophagitis (EoE), imeko abantu abaninzi abangayaziyo, kodwa ebangela ukungakhululeki okunjalo.
Yintoni i-Eosinophilic Esophagitis (EoE)?
Ngamafutshane, i-Eosinophilic Esophagitis (EoE) yimeko ye-allergy eyenzeka kwi -esophagus yethu, ityhubhu ethwala ukutya ukusuka emlonyeni ukuya esiswini.
Cinga ngenkqubo yethu yomzimba yokuzikhusela njengomkhosi okhusela ilizwe. Uhlobo olulodwa olukhethekileyo lwamajoni kulo mkhosi lubizwa ngokuba yi-eosinophils . Ezi luhlobo lweeseli ezimhlophe zegazi. Umsebenzi wazo uhlala kukulwa nezinto eziyingozi, ezifana neentsholongwane, ezingena emzimbeni.
Kodwa kukho into eyahlukileyo eyenzekayo kumntu one-EoE. Apha, inkqubo yethu yomzimba yokuzikhusela iyaphambana kancinci, iphambanisa ukutya okuthile (izinto ezibangela ukutya) okanye izinto ezikwindawo (izinto ezibangela i-allergens) notshaba. Ngenxa yesi sibonakaliso singalunganga, inani elikhulu lamajoni e-eosinophil liza lize liqokelele kwi-esophagus. Liza apho lize liqale umlo. Ngenxa yalo mlo, iindonga ze-esophagus ziyavuvukala kwaye ziyavutha .
Kwenzeka ntoni xa oku kudumba kusenzeka? Umphimbo uyancipha ngaphakathi. Njengokuba uthuli lubhajwa kumbhobho wamanzi, luyancipha. Kulapho sifumana ubunzima bokuginya ukutya, kwaye kuvakala ngathi ukutya kubhajwe.
Ziziphi iimpawu eziphambili zale meko?
Iimpawu ze-EoE zinokwahluka kancinci ngokweminyaka, kodwa ezi zezona mpawu zixhaphakileyo.
| Uphawu | Inkcazo |
|---|---|
| Ubunzima bokuginya (i-Dysphagia) | Olu luphawu oluphambili. Ukuziva kunzima ukuginya ukutya ngelixa usitya. Ukufuneka uginye kancinci. |
| Ukuminxeka kumbhobho wokutya | Ukuziva ngathi iqhekeza lokutya linamathele emqaleni, alikho phantsi okanye alinyuki. Ngamanye amaxesha oku kungaba yingxamiseko kwaye kunokufuneka uye kwigumbi likaxakeka. |
| Intlungu yesifuba okanye ukudumba | Usenokuba nesitshiso sentliziyo okanye iintlungu esifubeni, ezifana ne-gastritis. Oku akunyangwa ngamayeza e-gastritis. |
| Ukuhlanza okanye isisu esibuhlungu | Ezi mpawu zixhaphake kakhulu kubantwana abancinci nakubantu abakwishumi elivisayo. |
Into ebalulekileyo kukuba ukuba le meko ayinyangwa kakuhle, ukudumba kwi-esophagus kunokwanda ngokuhamba kwexesha kwaye kubangele amanxeba. Oku kunokubangela ukuba i-esophagus ibe ncinci ngakumbi kwaye kubenze babe mandundu iimpawu.
Iphathwa njani le nto ngeyeza i-Eohilia?
I-Eohilia liyeza elenziwe ngolwelo elisetyenziselwa ukunyanga i-EoE. Liqulethe iyeza elibizwa ngokuba yi-budesonide . I-Budesonide luhlobo lwe -corticosteroid . Isebenza ngokunciphisa ukudumba, okanye ukudumba, emzimbeni.
Xa usela i-Eohilia, ulwelo luya ngqo eludongeni lomqala luze lufunxwe kuyo. Kufana nokusebenzisa amayeza enxebeni. Xa lifunxwe, iyeza linciphisa ngokuthe ngqo inani laloo eosinophils iphazamisayo kumqala. Likwalawula umsebenzi ongafunekiyo wenkqubo yomzimba yokuzikhusela kwaye linciphisa ukudumba.
Njengoko ukudumba kuncipha, i-esophagus iyavuleka kancinci kancinci, nto leyo enciphisa ubunzima bokuginya. Eli yeza likwathintela umonakalo ongakumbi kwi-esophagus.
Ungayisebenzisa njani i-Eohilia?
I-Eohilia liyeza elenziwe ngolwelo. Ngokuqhelekileyo kucetyiswa ukuba isetyenziswe kabini ngemini (kusasa nangokuhlwa) kangangeeveki ezili-12. Iza kwiipakethi ezincinci (iipakethi ezinamathelayo) eziqulethe idosi enye.
Kusetyenziswa kwanjani:
1. Lungisa: Thatha ipakethi yamayeza uze uyishukumise kakuhle ubuncinane imizuzwana eli-10 . Oku kuya kuxuba kakuhle ulwelo olungaphakathi kwaye kukwenze kuphume lula.
2. Sela iyeza: Vula ipakethi uze ugalele lonke ulwelo emlonyeni wakho. Emva koko uliginye lonke.
3. Hlamba umlomo wakho: Emva kwemizuzu engama-30 uginye iyeza, hlambulula umlomo wakho kakuhle ngamanzi uze ulitshice. Oku kwenzelwa ukuthintela iziphumo ebezingalindelekanga ezifana ne-oral thrush.
Kubaluleke kakhulu: Musa ukutya okanye ukusela nantoni na imizuzu engama-30 emva kokuthatha i-Eohilia. Eli lixesha lokuba iyeza lingene kwindlela yokugaya ukutya kwaye lisebenze kakuhle.
Kwakhona, kuphephe ukusela ijusi yegrapefruit ngelixa usela eli yeza, kuba lisenokuphazamisa ukusebenza kakuhle kweli yeza. Musa ukuyeka ukuthatha eli yeza ngequbuliso ngaphandle kwengcebiso kagqirha wakho.
Luthini uphando oluphathelele eli yeza?
Kuye kwenziwa uvavanyo lwezonyango ezimbini ukuphanda ukusebenza kakuhle kwe-Eohilia. Oku kubandakanye abantu abaneminyaka eli-11 nangaphezulu abane-EoE. Aba bantu bahlulwe baba ngamaqela amabini, elinye iqela lanikwa i-Eohilia kwaye elinye iqela lanikwa i-placebo kangangeeveki ezili-12.
Iziphumo zophando zibonise ngokucacileyo ukuba abo bathathe i-Eohilia babenobunzima obuncinci bokuginya kunabo bathathe i-placebo. Kwakhona kwaqinisekiswa ukuba inani lee-eosinophils kwi-esophagus yabo bathathe i-Eohilia lehle ngepesenti ephezulu kakhulu . Oku kubonisa ukuba eli yeza lilawula ngokuthe ngqo ukudumba okubangela esi sifo.
Kuthatha ixesha elingakanani ukubona iziphumo zeyeza?
Kungathatha iiveki ezimbalwa ukubona iziphumo ezipheleleyo ze-Eohilia. Ngoko ke ungakhathazeki ukuba awuziva mahluko mkhulu ngoko nangoko. Yiba nomonde kwaye uqhubeke nokusebenzisa amayeza njengoko kuyalelwe. Ukuba unamathandabuzo malunga nokuba amayeza ayasebenza okanye ayasebenza, thetha nogqirha wakho ngawo.
Ngaba kukho iingxaki ngamanye amayeza?
Ewe, amanye amayeza anokusebenzisana ne-Eohilia. Ngoko ke xa ubona ugqirha wakho, mxelele ngawo onke amayeza owasebenzisayo ngoku. Oko kuthetha amayeza abhalwe ngugqirha, amayeza athengiswa ngaphandle kwemvume kagqirha, iivithamini, amayeza emifuno, kunye nezongezo zemifuno.
Amanye amayeza, ingakumbi lawo athintela i-enzyme ye-CYP3A4 emzimbeni wethu, akufuneki asetyenziswe ne-Eohilia. Ugqirha wakho uza kukunika iingcebiso ngale nto.
Uyazi njani ukuba iyeza liyasebenza?
Eyona ndlela ilungileyo yokwazi oku kukulandelela iimpawu zakho. Ngaphambi kokuba uqale ukuthatha amayeza, gcina ingxelo yokuba unengxaki kangakanani yokuginya ukutya kunye nokutya okubambekayo. Emva kweeveki ezimbalwa usebenzisa amayeza, jonga ukuba ukungakhululeki kuye kwehla na. Ngale ndlela, ukulandelela iimpawu zakho kuya kunceda wena nogqirha wakho nazi ukuba amayeza ayasebenza na.
Umyalezo Wokuya Ekhaya
- I-Eosinophilic Esophagitis (EoE) yimeko ebangela ukunganyamezelani komzimba echaphazela umqala. Kule meko, umqala uyavuvukala ngenxa yokungasebenzi kakuhle kwenkqubo yomzimba yokuzikhusela.
- Ubunzima bokuginya, ukutya okubambekayo, kunye nentlungu esifubeni zezona mpawu ziphambili.
- I-Eohilia liyeza le-corticosteroid elingamanzi elisetyenziselwa ukunyanga le meko. Linciphisa ukudumba emqaleni.
- Xa usebenzisa iyeza, kubaluleke kakhulu ukuyeka ukutya okanye ukusela imizuzu engama-30 emva kokulisebenzisa uze uhlambe umlomo wakho emva koko.
- Ukuba uqhubeka nobunzima bokuginya, musa ukungayinaki kwaye cela ingcebiso kugqirha ngokukhawuleza.
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