Ngaba ugqirha wakho uthe i-cholesterol yakho, ingakumbi i-triglycerides, iphezulu kuvavanyo lwakho lwegazi lwakutshanje? Okanye ngaba uthe inqanaba lakho le-HDL (i-cholesterol elungileyo) liphantsi? Ngexesha elinje, kukho ithuba elihle lokuba ugqirha wakho uya kukuxelela ukuba uqale unyango olubizwa ngokuba yi-Fibrates. Ngoko ke ungoyiki xa usiva eli gama. Namhlanje, siza kuthetha ngezinto ezi zi-Fibrates, indlela ezilunge ngayo emzimbeni, kunye nento ekufuneka uyilumkele.
Zithini ii-fibrates? Zisebenza njani emzimbeni?
Ngamafutshane, iiFibrates ludidi lwamayeza anceda ukulawula iintlobo zamafutha egazini lethu. La mayeza enza izinto ezimbini:
1. Ukunciphisa iiTriglycerides: IiTriglycerides luhlobo lwamafutha aqokelelana egazini emva kokutya. Xa sele ephezulu kakhulu, agcinwa kwiiseli zethu zamafutha. Amanqanaba aphezulu ala mafutha anokukhokelela kwisifo sentliziyo kunye nemeko eyingozi ebizwa ngokuba yi-pancreatitis , oku kukudumba kwepancreas. IiFibrates zisebenza ngokunciphisa ubungakanani be-triglycerides eveliswa sisibindi.
2. Ukunyusa i-cholesterol elungileyo (i-HDL): Usenokuba uvile ukuba kukho iintlobo ezimbini ze-cholesterol, 'elungileyo' kunye 'nembi'. I-HDL (i-High-Density Lipoprotein) yinto ebizwa ngokuba yi -cholesterol 'elungileyo' . Ii-Fibrates zinokunceda ukwandisa eli nqanaba le-cholesterol elungileyo.
Kodwa into enye ekufuneka uyikhumbule: Ii-fibrates azinciphisi kakhulu amanqanaba e-LDL (Low-Density Lipoprotein), abizwa ngokuba yi-'cholesterol embi' . Zikho nezinye iindlela zokwenza loo nto.
Ngubani ofuna olu hlobo lonyango?
Eyona nto iphambili ugqirha wakho aya kukunika eli yeza kukuba amanqanaba e-triglyceride egazini lakho aphezulu kakhulu. Ii-Fibrates ziyindlela ebaluleke kakhulu yokunciphisa umngcipheko wokuba ne -pancreatitis, ukudumba kwe-pancreas, ngenxa yala manqanaba aphezulu e-triglyceride.
Nangona i-triglycerides ephezulu inxulunyaniswa nomngcipheko okhulayo wesifo sentliziyo, ii-fibrates azikabonakali ukuba ziyawunciphisa umngcipheko wokuhlaselwa sisifo sentliziyo okanye isifo sohlangothi. Amanye amayeza, afana nee-statins, asetyenziswa kakhulu kule njongo. Ke ngoko, injongo ephambili yale chiza kukunciphisa umngcipheko we-pancreatitis.
Ziziphi iintlobo ze-fibrates kwaye ziphumelela kangakanani?
Kukho iintlobo ezahlukeneyo zamayeza akwiqela le-fibrates. Ugqirha wakho angakunika enye yala mayeza.
| Igama eliqhelekileyo lesiyobisi | Amanye Amagama Eempawu Kwimarike |
|---|---|
| I-Fenofibrate | I-TriCor®, i-Fibricor®, i-Lofibra® |
| I-Gemfibrozil | I-Lopid® |
| I-Clofibrate | I-Atromid-S® |
Lisebenza kangakanani eli yeza?
IiFibrates ngamayeza asebenze kakuhle kwabanye abantu. Uphando lubonise ukuba zinokwenza oku kulandelayo:
- Yehlisa amanqanaba e-triglyceride malunga ne- 50% .
- Ukunyusa amanqanaba e-cholesterol elungileyo (i-HDL) malunga ne- 20% .
- Yehlisa amanqanaba e-cholesterol iyonke malunga ne- 10% .
Akwanelanga na ukusebenzisa ii-fibrates zodwa? Yintoni enye endifanele ndiyenze?
Ngamanye amaxesha, ii-fibrates zodwa zinokwanela ukunciphisa i-triglycerides. Nangona kunjalo, ukuba usengozini yesifo sentliziyo, ugqirha wakho unokukunika olunye uhlobo lonyango lokunciphisa i-cholesterol olubizwa ngokuba yi-statins kunye nale mayeza.
Xa la mayeza mabini esetyenziswa kunye, abanye abantu banokuba nomngcipheko okhulayo weengxaki zemisipha . Ngoko ke ugqirha wakho uza kukujonga ngokusondeleyo. Kodwa ungakhathazeki, abantu abaninzi basebenzisa la mayeza mabini kunye ngaphandle kweengxaki.
Eyona nto ibalulekileyo kukuba amayeza odwa awanelanga. Kunye namayeza, kufuneka wenze olu tshintsho kwindlela ophila ngayo:
- Ukutya okunempilo kwentliziyo: Nciphisa ukutya okuneoyile eninzi, iswekile, kunye nomgubo, kwaye utye imifuno emininzi, iziqhamo, imifuno eluhlaza kunye nokutya okunefayibha eninzi.
- Ukuzilolonga: Zilolonge ubuncinane imizuzu eli-150 ngeveki. Nokuba uhamba ngokukhawuleza kwanele.
- Ukulawula uxinzelelo: Gxila kwizinto ezikunika uxolo lwengqondo. Izinto ezifana nokucamngca nokumamela umculo zinokunceda.
- Lala kakuhle: Qiniseka ukuba ulala ubuncinane iiyure ezisi-7-8 ngobusuku.
- Ukuyeka ukutshaya: Yeka ukutshaya kunye neemveliso zecuba ngokupheleleyo.
Iziphumo ebezingalindelekanga kunye nokusebenzisana namanye amayeza
Njengayo nayiphi na imithi, ii-fibrates zinokubangela iziphumo ebezingalindelekanga ezincinci kwabanye abantu, kodwa ayinguye wonke umntu ozifumanayo.
| Iziphumo ebezingalindelekanga eziqhelekileyo | Ukusebenzisana namanye amayeza |
|---|---|
|
Ndingalithatha ixesha elingakanani eli yeza? Ngubani ongafanele alithathe?
IiFibrates zihlala zisetyenziswa ixesha elide. Musa ukuyeka ukuzisebenzisa ngaphandle kokuba ugqirha wakho ekuxelele ukuba wenze njalo. Uza kujonga igazi lakho rhoqo ukuqinisekisa ukuba amayeza ayasebenza kwaye amanqanaba akho aphantsi kolawulo.
Iimeko ezingafanelekanga zokuthatha eli yeza:
Eli yeza lisenokungafaneleki kwabanye abantu. Ukuba unenye yezi meko zilandelayo, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ngaphambi kokuba uqale ukusebenzisa iyeza.
- Ukuba ukhulelwe okanye ungumama oncancisayo
- Ukuba une-allergies kula mayeza
- Ukuba unesifo seswekile
- Ukuba uneengxaki zezintso, zesibindi, okanye zenyongo
- Ukuba ujongene nento ethile kwixesha elizayo, njengotyando okanye ukukhutshwa kwamazinyo
Ukuba ufumana ezi mpawu, bonana nogqirha ngokukhawuleza!
Ukuba ufumana naziphi na iimpawu ezilandelayo ngelixa usebenzisa eli yeza, xelela ugqirha wakho ngoko nangoko. Ngamanye amaxesha ezi zinokuba ziimpawu zesifo esinzulu.
- Intlungu egqithisileyo yemisipha okanye ubuthathaka obuvela ngaphandle kwesizathu
- Intlungu engapheliyo yesisu
- Ukuqhambuka kwesikhumba
- Ukutyheli kolusu okanye amehlo (i-Jaundice)
Ukuba uziva into efana nale, musa ukwenza izigqibo wedwa, bonana nogqirha ngokukhawuleza. Ukuba kuyimfuneko, ungathandabuzi ukuya kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele.
Umyalezo Wokuya Ekhaya
- IiFibrates luhlobo lwamayeza anciphisa i-triglycerides egazini kwaye anyuse i-cholesterol elungileyo (i-HDL).
- Eyona njongo iphambili yoku kukuthintela i-pancreatitis, enokubangelwa yi-triglycerides ephezulu.
- Eli yeza lifanele lisetyenziswe kuphela phantsi kwengcebiso kagqirha. Thatha iyeza njengoko kuyalelwe, ngokwemilinganiselo emiselweyo, nangexesha elimiselweyo.
- Amayeza ewodwa awanelanga. Kubalulekile ukulandela ukutya okunempilo kwentliziyo, ukuzilolonga, kunye nendlela yokuphila enempilo.
- Ukuba ufumana naziphi na iimpawu ezingaqhelekanga ezifana neentlungu zemisipha, iintlungu zesisu eziqatha, okanye ukutyheli kolusu, yazisa ugqirha wakho ngoko nangoko.
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