Amaqhawe amancinci emizimbeni yethu - yonke into malunga neeseli ze-beta!

Ngaba wakha wazibuza ukuba zingaphi izinto ezimangalisayo ezenzekayo emizimbeni yethu? Izigidi zeeseli, ezincinci kangangokuba azibonakali emehlweni, zisigcina siphila. Namhlanje siza kuthetha ngezinye zezo ziqhawe zincinci zeeseli ezibalulekileyo, kodwa ezingaziwayo. Ziiseli ze-beta. Ngamafutshane, ezi zibizwa ngokuba 'ziiseli ze-beta'. Masibone ukuba ngoobani ezi seli ze-beta, zenzani, kwaye kwenzeka ntoni ukuba zilahlekile.

Zithini ii-beta cells? Ziphi?

Kulungile, masiqale sibone ukuba zeziphi iiseli ezi ze-beta. Ezi luhlobo olukhethekileyo lweeseli. Umsebenzi wazo ophambili kukuvelisa into efunekayo emzimbeni wethu, i-hormone. Ibizwa ngokuba yi -insulin .

Ngoku ubuza, "Kulungile, ziphi ke ezi seli ze-beta ezifumaneka emzimbeni?" Zifumaneka kwilungu elincinci kodwa elibaluleke kakhulu ngaphakathi esiswini sethu, emva kancinci kwesisu. Sibiza elo lungu ngokuba yi-pancreas . I-pancreas yindlala. Oko kukuthi, yindawo apho iikhemikhali ezahlukeneyo ziveliswa kwaye zikhutshwa khona. Kukho amaqela amancinci eeseli ezifana neziqithi apha naphaya kule pancreas. Ezo qela zeeseli zilapho uninzi lwezi seli ze-beta lufumaneka khona. Ukuchaneka, ezi ndawo zifana neziqithi zibizwa ngokuba yi-'Islets of Langerhans'. Elo ligama lesayensi, kodwa kulungile ukwazi.

Umlingo we-insulin!

Sisandula ukutsho ukuba ii-beta cells zivelisa i-hormone ebizwa ngokuba yi-insulin. Yintoni kanye kanye i-insulin? Yintoni eyenzayo?

Ngamafutshane, i-insulin yi-hormone ebaluleke kakhulu elawula inqanaba leswekile, okanye i-glucose, egazini lethu. Cinga ngale ndlela. Xa sisitya ukutya, ii-carbohydrates ezikuloo nto yokutya ziyagaywa kwaye ziguqulwe zibe yi-glucose. Le glucose yeyona fuel iphambili enika amandla kwiiseli zomzimba wethu. Ifana nepetroli yemoto.

Kodwa, akwanelanga ukuba le glucose ihlale egazini. Kufuneka ingene kwiitriliyoni zeeseli emizimbeni yethu ukuze ivelise amandla. Kulapho ke i-insulin inceda khona.

I-insulin isebenza njengesitshixo. Yisitshixo esivula iingcango zeeseli zomzimba wethu kwaye sivumele i-glucose ukuba ingene.

Ngoko ke, ngaphandle kwe-insulin, i-glucose egazini ayinakungena kwiiseli. Emva koko inqanaba le-glucose egazini liyaqhubeka nokunyuka. Oko akulunganga emzimbeni konke konke.

Besiya kuba yintoni ngaphandle kweglucose?

Makhe sithethe kancinci ngeglucose, kuba iglucose ngumlinganiswa ophambili kweli bali lee-beta cells kunye ne-insulin.

Njengoko besitshilo ngaphambili, i-glucose yeyona fuel iphambili enika amandla emizimbeni yethu. Yonke into esiyenzayo - ukuphefumla, ukucinga, ukuhamba, ukubaleka, ukutsiba - ifuna amandla. Loo mandla avela kwi-glucose.

Sifumana iglucose kwiintlobo ngeentlobo zokutya esikutyayo, okufana nerayisi, isonka, iitapile, iitapile ezimnandi, kunye neziqhamo. Xa ezi zinto zigayiwe, zijika zibe yiglucose zize zingene egazini.

• Ukuba amanqanaba eglucose egazini anda kakhulu: Oku kunokubangela umonakalo owahlukeneyo emzimbeni. Ukuba amanqanaba eglucose egazini aphezulu ixesha elide, anokonakalisa amalungu abalulekileyo afana namehlo, izintso, imithambo-luvo kunye nentliziyo.
• Ukuba amanqanaba eglucose egazini ehla kakhulu (iHypoglycemia): Naloo nto yingxaki. Emva koko umzimba unokufumana iimpawu ezifana nokungabi namandla, ukudinwa, isiyezi, kunye nokubila.

Kungoko ke, kubaluleke kakhulu ukugcina inqanaba leswekile egazini likwinqanaba elifanelekileyo. Yiloo nto i-insulin eveliswa zii-beta cells zethu inceda kuyo.

I-Pancreas - Umzi-mveliso omncinci emzimbeni wethu!

Ngoku siyazi ukuba ii-beta cells zifumaneka kwi-pancreas. Eli lungu libizwa ngokuba yi-pancreas lifana nomzi-mveliso omncinci. Alisebenzi nje umsebenzi omnye.

• Ukuveliswa kwe-insulin: Oku kwenziwa zii-beta cells.
• Ukuveliswa kwezinye iihomoni: Ezinye iintlobo zeeseli kwi-pancreas zivelisa ezinye iihomoni, ezifana ne-glucagon. Ihomoni i-glucagon yenza okwahlukileyo koko kwenziwa yi-insulin. Oko kukuthi, xa inqanaba le-glucose egazini lihla, inceda ukuyibuyisela kwinqanaba elifunekayo.
• Ukuncedisa ekugayweni kokutya: Ii-enzymes eziveliswa yi-pancreas zinceda ekugayweni kweeproteni, amafutha kunye nee-carbohydrates ekutyeni esikutyayo.

Ubonile? I-pancreas sisitho esincinci kodwa esibalulekileyo. Ngoko ke ukuba kukho into eyonakeleyo kwiiseli ze-beta ezikuyo, ichaphazela umzimba wethu wonke.

Ubudlelwane phakathi kwesifo seswekile sohlobo 1 kunye neeseli ze-beta

Mhlawumbi ukhe weva ngesifo "seswekile." Kukho iintlobo ezimbini eziphambili zesifo seswekile. Ziyi-Type 1 Diabetes kunye ne-Type 2 Diabetes. Kuzo zombini, okwenzekayo kwiiseli zethu ze-beta kwahlukile kancinci.

Okwenzekayo kwimeko yesifo seswekile sohlobo loku-1 esithetha ngaso namhlanje yinto ebuhlungu kakhulu. Sinenkqubo emizimbeni yethu efana nomkhosi wokhuselo, akunjalo? Isikhusela ngokulwa neentsholongwane ezibangela izifo ezivela ngaphandle. Yiloo nto siyibiza ngokuba yinkqubo yokuzikhusela . Ngokwesiqhelo, le nkqubo yokuzikhusela ikrelekrele kakhulu, iyaziqonda iiseli zethu kwaye ayizitshabalalisi, kodwa ihlasela kuphela iintshaba ezivela ngaphandle.

Nangona kunjalo, nantsi into eyenzekayo emzimbeni womntu onesifo seswekile sohlobo loku-1:Inkqubo yomzimba yokuzikhusela ihlasela ngempazamo ezo seli ze-beta zimsulwa. Oko kukuthi, umkhuseli wethu utshabalalisa iiseli zethu. Le meko siyibiza ngokuba "sisifo sokuzikhusela ngokwasemzimbeni."

Ngoko ke, njengoko inkqubo yomzimba yokuzikhusela iqhubeka nokutshabalalisa ii-beta cells, amandla epancreas okuvelisa i-insulin ayancipha kancinci kancinci. Ekugqibeleni, xa ii-beta cells ziphantse zatshatyalaliswa ngokupheleleyo, umzimba awusakwazi ukuvelisa i-insulin.

Isifo seswekile sohlobo loku-1 asisosifo esibangelwa yimpazamo yomntu okanye ukungakwazi ukulawula ukutya kwakhe, kodwa sisifo esibangelwa kukutshintsha kwenkqubo yomzimba yokuzikhusela.

Kuthekani ukuba inkqubo yokuzikhusela yomzimba wethu iyaphambuka? - Okuncinci malunga neNkqubo yoKhuseleko loMzimba

Makhe sithethe kancinci ngenkqubo yomzimba yokuzikhusela, kuba le yinto ephambili emisela ikamva leeseli ze-beta.

Inkqubo yethu yomzimba yokuzikhusela ngokuqhelekileyo yinkqubo ekrelekrele kakhulu nentsonkothileyo.

• Bayazazi iintsholongwane ezifana neebhaktheriya kunye neentsholongwane ezingena emizimbeni yethu.
• Balwa nabo kwaye basikhusela kwizifo.
• Ikwanceda ekutshabalaliseni iiseli ezingaqhelekanga, ezifana neeseli zomhlaza, ezikhula emzimbeni.

Nangona kunjalo, ngamanye amaxesha nale nkqubo ikrelekrele yenza iimpazamo. Kungeempazamo ezinjalo apho iiseli zethu eziphilileyo ziqatshelwa "njengeentshaba" kwaye ziqale ukuzihlasela. Oku kwenzeka kwiiseli ze-beta kwiSifo seswekile sohlobo loku-1. Izazinzulu azikafumani unobangela ochanekileyo woku. Okwangoku kukholelwa ukuba indibaniselwano yezinto zemfuza kunye nezinto ezingqongileyo zibangela le meko.

Kwenzeka ntoni xa iiseli ze-beta zilahlekile?

Khawucinge ngento eyenzekayo xa ii-beta cells zitshatyalaliswa kancinci kancinci kwaye umzimba ungakwazi ukuvelisa i-insulin eyaneleyo.

1. Akukho insulin: Oku kuthetha ukuba iglucose egazini ayinandlela yokungena kwiiseli.

2. Amanqanaba eglucose egazini ayanda (iHyperglycemia): Yonke iglucose engenakungena kwiiseli iqokelelana egazini.

3. Iiseli azinawo amandla: Ngaphandle kweglucose, iiseli azinawo amandla okusebenza.

Ngenxa yesi simo, iimpawu ezahlukeneyo ziqala ukubonakala.

• Ukoma rhoqo (iPolydipsia): Ngenxa yeswekile ephezulu egazini, umzimba uzama ukuyinyibilikisa ngokusela amanzi amaninzi.
• Ukuchama rhoqo (i-Polyuria): Izintso zizama ukukhupha i-glucose egqithisileyo emzimbeni ngomchamo.
• Ukudinwa: Umzimba uziva udiniwe kakhulu kuba iiseli azinamandla.
• Nangona inkanuko isanda, ukwehla kobunzima kuyenzeka:Ekubeni iiseli zingenakufumana amandla kwi-glucose, ziqala ukusebenzisa amafutha agciniweyo kunye neeproteni ukuze zifumane amandla. Ngenxa yoko, umzimba uba mncinci.
• Umbono ofipheleyo: Xa amanqanaba eswekile egazini enyuka ngequbuliso, ilensi yeliso inokuchaphazeleka, nto leyo ebangela umbono ofipheleyo.

Ukuba ufumana naziphi na kwezi mpawu, kubalulekile ukufuna ingcebiso kagqirha ngoko nangoko. Abantu abanesifo seswekile sohlobo loku-1 kuya kufuneka bathathe i-insulin ubomi babo bonke, nokuba kungokujova okanye ngepompo ye-insulin.

Ngaba ikho indlela yokuthintela umonakalo kwiiseli ze-beta okanye ukuzakha kwakhona?

Lo ngumbuzo obaluleke kakhulu. Ngenxa yokuba isifo seswekile sohlobo loku-1 sisifo esibangelwa kukuzikhusela komzimba, okwangoku akukho ndlela icacileyo yokusithintela. Oko kuthetha ukuba kunzima ukuthi, "Ukuba wenza oku, ungasithintela isifo seswekile sohlobo loku-1."

Nangona kunjalo, izazinzulu zihlala ziphanda oku.

• Ungayithintela njani inkqubo yomzimba yokuzikhusela ekuhlaseleni iiseli ze-beta?
• Ngaba iiseli ze-beta ezitshatyalalisiweyo zinokuphinda zivuselelwe?
• Okanye, ngaba iiseli ezintsha ze-beta zinokufakwa emzimbeni?

Bazama ukufumana iimpendulo kwimibuzo efana nale. Izinto ezifana nokufakelwa kwepancreas kunye nokufakelwa kweeseli ze-islet sele ziphumelele ngandlela thile. Kukwakho nemizamo yophando yokwenza iiseli ze-beta kwiiseli ze-stem kunye nokuzisebenzisa. Kungacingelwa ukuba ezi ziya kuzisa ithemba elikhulu kubantu abanesifo seswekile sohlobo loku-1 kwixesha elizayo.

Eyona nto ingcono onokuyenza ngoku kukuba umntu onesifo seswekile sohlobo loku-1 athathe unyango lwe-insulin njengoko ugqirha wakhe emxelele, ajonge amanqanaba eglucose egazini lakhe rhoqo, atye ukutya okunesondlo, aze aphile ubomi obusempilweni.

Kutheni sonke sifanele siqaphele ezi seli ze-beta?

Cinga nje ngomsebenzi owenziwa zezi beta cells zincinci emizimbeni yethu. Ngoko ke, kubalulekile ukuba sonke sazi ngazo.

• Fumana ukuqonda ngemizimba yethu: Olu lwazi lusinceda siqonde indlela esebenza nzima nemangalisayo ngayo imizimba yethu.
• Ulwazi ngesifo seswekile: Xa siqonda ukuba siyintoni isifo seswekile sohlobo 1, indlela esikhula ngayo, kunye nokuba sibangelwa yintoni, sinokubaxhasa size sibaqonde abo baphila nale meko.
• Isikhokelo soBomi obuPhilileyo: Ukuqonda ukubaluleka kokulawula amanqanaba eglucose egazini, sonke sikhuthazwa ukuba siqaphele ngakumbi ukutya kwethu nendlela esiphila ngayo. (Oku kubaluleke ngakumbi kwiSifo seswekile soHlobo lwesibini, kodwa kubalulekile kwimpilo ngokubanzi).

Izinto ezibalulekileyo ekufuneka uzikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, masiphinde sijonge ezona zibakala zibalulekileyo malunga neeseli ze-beta esithethe ngazo namhlanje.

• Iiseli zeBeta luhlobo olukhethekileyo lweeseli ezifumaneka kwi-pancreas.
• Umsebenzi wabo ophambili kukuvelisa i-hormone ebizwa ngokuba yi-insulin.
• I-insulin ilawula inqanaba le-glucose egazini. Oko kukuthi, inceda i-glucose ingene kwiiseli.
• Kwisifo seswekile sohlobo loku-1, inkqubo yethu yomzimba yokuzikhusela iyazitshabalalisa ngempazamo ezi seli ze-beta.
• Xa iiseli ze-beta zitshatyalalisiwe, umzimba awukwazi ukuvelisa i-insulin, ngoko ke amanqanaba eglucose egazini ayanyuka.

Ngoko ke, ngoku uyaqonda ukuba ezi seli zincinci ze-beta zibaluleke kangakanani kwimpilo yemizimba yethu. Ukuzazi ezi zinto kuya kusinceda kakhulu ekunyamekeleni impilo yethu kunye nempilo yabantu esibathandayo.

Ukuba unemibuzo engaphezulu malunga noku, ungathandabuzi ukubuza ugqirha. Hlala usempilweni!

Iiseli zeBeta , i-insulin, iglucose, ipancreas, isifo seswekile, uhlobo 1 lweswekile, inkqubo yomzimba yokuzikhusela