Xa ugqirha wakho ekubhalela iyeza elibizwa ngokuba yiLarotrectinib okanye umntu omaziyo, kuyinto eqhelekileyo ukuba nemibuzo emininzi ngalo. Loluphi uhlobo lweyeza eli? Kuza kwenzeka ntoni ngalo? Ngaba kukho naziphi na iziphumo ebezingalindelekanga? Usenokuba uzibuza. Ungakhathazeki. Masithethe ngeli yeza ngokulula, ngendlela onokuyiqonda.
Yintoni iLarotrectinib?
Ngamafutshane, i-larotrectinib luhlobo oluthile lonyango oluthintela ukukhula kweeseli zomhlaza. Oku kubizwa ngokuba 'lunyango olujoliswe kuyo'. Oku kuthetha ukuba eli yeza liya ngqo kwiproteni ethile kwiiseli zomhlaza kwaye lichaphazela kuphela iproteni ethile kwiiseli zomhlaza, lithintela ezo seli ekukhuleni.
Kodwa eli ayiloyeza elinikwa zonke iintlobo zomhlaza. Iiseli zakho zomhlaza ziyavavanywa ukuze kubonwe ukuba zinenguqu ekhethekileyo kwijini ebizwa ngokuba yi-NTRK (neurotrophic receptor tyrosine kinase gene fusion) . Ngabantu abanenguqu yejini kuphela abaya kuzuza kweli yeza. Ngoko ke ukuba ugqirha wakho ukunike eli yeza, oko kuthetha ukuba uhlobo lomhlaza wakho lunokusabela kakuhle kulo.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukunika ugqirha wakho inkcazo epheleleyo yemeko yakho yempilo. Qiniseka ukuba ubaxelela oku kulandelayo ngokukodwa:
| Imeko | Oko kufuneka ukwazise |
|---|---|
| Isifo sesibindi | Ukuba unesifo sesibindi. |
| Ingxaki yemithambo-luvo | Ukuba amalungu akho ayarhawuzelela okanye unezinye iingxaki zemithambo-luvo. |
| Ii-aleji | Ukuba une-allergy kule yeza, amanye amayeza, ukutya, okanye iidayi. |
| Ukukhulelwa | Ukuba ukhulelwe, uzama ukukhulelwa, okanye unamathandabuzo ngayo loo nto. |
| Ukuncancisa | Ukuba uncancisa umntwana wakho. |
Ndingayisebenzisa njani le yeza?
Eyona nto ibalulekileyo kukuthatha amayeza kanye njengoko ugqirha etshilo.
- Ginya le kapsule yonke ngeglasi yamanzi .
- Musa ukuphula, ukutyumza, okanye ukuhlafuna ikhapsuli.
- Ungayithatha le nto ngaphambi okanye emva kokutya. Kodwa, zama ukuyithatha ngexesha elifanayo yonke imihla .
- Kubaluleke kakhulu: Ungaze uthathe eli yeza kunye nejusi yegrapefruit.
- Musa ukuyeka ukuthatha amayeza akho ngaphandle kwengcebiso kagqirha wakho.
Ukuba inikwa abantwana: Eli yeza ngamanye amaxesha linokunikwa nabantwana abancinci. Nangona kunjalo, lifuna amanyathelo akhethekileyo okhuseleko. Thetha nogqirha wezingane ngale nto.
Yintoni omawuyenze ukuba idosi iyanda (i-overdose)?
Ukuba ucinga ukuba usele kakhulu eli yeza, ungoyiki. Tsalela umnxeba iZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko. Okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele esikufutshane.
Kuthekani ukuba ndilibele ukusela amayeza am?
Ukuba uphoswe yidosi, yithathe ngokukhawuleza xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezi-6 ngaphambi kokuba idosi yakho elandelayo ifike, yitsibe idosi oyiphosileyo uze uthathe idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye.
Ezinye izinto ezinokusebenzisana nale mithi (Intsebenziswano)
Eli yeza lisenokusebenzisana namanye amayeza nokutya. Ngoko ke, xelela ugqirha wakho ngayo yonke into oyithathayo. Oku kuquka amayeza kagqirha, amayeza athengiswa ngaphandle kwemvume kagqirha, iimveliso zemifuno, iivithamini, kunye nezongezo. Kwakhona, xelela ugqirha wakho ukuba utshaya okanye usela utywala.
Nazi ezinye zezinto ezinokudibana nale mithi.
- Amayeza e-HIV okanye i-AIDS
- Amanye amayeza okubulala iintsholongwane (afana ne-clarithromycin)
- Amayeza osulelo lwefungus (njenge ketoconazole)
- Amayeza okuxhuzula (afana ne-carbamazepine, i-phenytoin)
- Amanye amayeza esifo sentliziyo
- Amayeza okunciphisa umzimba (afana ne-cyclosporine, i-tacrolimus)
- Amanye amayeza okulwa nomhlaza (i-chemotherapy)
- Imifuno yeSt. John's Wort
- Ijusi yegrapefruit
Olu luhlu aluphelelanga, ngoko ke kubalulekile ukwazisa ugqirha wakho malunga nawo onke amayeza owasebenzisayo.
Izinto ekufuneka ziqwalaselwe xa usebenzisa amayeza
- Uvavanyo lwegazi: Ngelixa usela eli yeza, ugqirha wakho uya kuyalela uvavanyo lwegazi ngamanye amaxesha ukujonga izinto ezifana nokusebenza kwesibindi sakho.
- Imisebenzi efuna ingqalelo: Eli yeza linokukwenza uzive unesizungu, ulele, okanye udidekile. Ngoko ke, yiphephe imisebenzi efuna ingqalelo, njengokuqhuba okanye ukusebenzisa oomatshini, ude wazi kakuhle ukuba oku kuyichaphazela njani umzimba wakho.
- Ukukhulelwa nokuncancisa (kubaluleke kakhulu):
- Abafazi: Kuphephe ukukhulelwa ngelixa usela eli yeza kwaye ubuncinane iveki enye emva kokuyeka iyeza. Ukuba uceba ukukhulelwa okanye ukrokrela ukuba ukhulelwe, xelela ugqirha wakho ngoko nangoko.
- Amadoda: Kuphephe ukuba nguyise womntwana ngelixa usebenzisa eli yeza kwaye ubuncinane iveki enye emva kokuba uyekile ukusebenzisa eli yeza.
- Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye emva kweveki enye uyekile.
- Ukuzala: Eli yeza lisenokuchaphazela amandla akho okufumana abantwana. Ukuba unemibuzo malunga noku, thetha nogqirha wakho.
Iziphumo ebezingalindelekanga zeyeza
Njengayo nayiphi na iyeza, eli linokuba nemiphumo emibi. Eminye incinci, ngelixa eminye ifuna ingqalelo ekhawulezileyo.
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
|---|---|
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Iimpawu zokulimala kwesibindi | Umchamo otyheli/omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, isicaphucaphu, ukungabi namdla wokutya, indle ekhanyayo. |
| Iingxaki zenkqubo yemithambo-luvo | Ukudinwa, ukudideka, ukulahlekelwa kukulinganisela, iintlungu okanye ukuba ndindisholo kwamalungu omzimba, ubunzima bokuthetha. |
| Iziphumo ebezingalindelekanga eziqhelekileyo ekufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Ukuhlanza | Urhudo |
| Ukuqhinwa | Ukukhwehlela |
| Ukudinwa | |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, thetha nogqirha wakho ngazo.
Umyalezo Wokuya Ekhaya
- I-Larotrectinib lunyango olujoliswe ngokukodwa kubantu abanomhlaza abane-NTRK gene fusion.
- Kubalulekile ukuxelela ugqirha wakho malunga nazo zonke ezinye iziyobisi, iimveliso zezityalo, kunye nezongezo ozithathayo.
- Musa ukusela ijusi yegrapefruit ngokupheleleyo ngelixa usebenzisa eli yeza.
- Landela amanyathelo okhuseleko angqongqo malunga nokukhulelwa, ukuncancisa, kunye nokuzala umntwana ngelixa usela amayeza kwaye emva kweveki enye uyekile.
- Funa uncedo lwezonyango ngokukhawuleza ukuba kukho iimpawu ezinjengokonakala kwesibindi okanye iingxaki ezinkulu zemithambo-luvo.
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