Xa wena okanye umntu osapho lwakho eqala unyango lomhlaza, kuyinto eqhelekileyo ukuba novalo kwaye ube nomdla malunga namayeza anikwa ngugqirha wakho. Kubalulekile ukuba nolwazi olupheleleyo xa uqala amayeza amatsha. Ngoko ke namhlanje siza kuthetha ngelinye lamayeza alwa nomhlaza, iLorlatinib. Masithethe ngayo ngokulula, ngokungathi umhlobo ukuchazela yona.
Yintoni iLorlatinib?
Ngamafutshane, i-lorlatinib ayisiyoyeza eliqhelekileyo le-chemotherapy. Isebenza "njengonyango olujoliswe kulo." Oku kuthetha ukuba ijolise ngqo kwiiproteni ezithile ezinceda iiseli zomhlaza zikhule. Ngokwenza njalo, iyayithintela iseli zomhlaza ekukhuleni.
Isetyenziswa kakhulu ukunyanga imeko ebizwa ngokuba yi "non-small cell lung cancer." Ugqirha wakho angakunika eli yeza nakwezinye iimeko. Ukuba unemibuzo ngalo, buza ugqirha wakho.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba ugqirha wakho akunike eli yeza, kubalulekile ukuba wazi ngokupheleleyo naziphi na ezinye iimeko zempilo onokuba nazo. Eli yeza lisenokudibana nezo meko. Ngoko ke, ukuba unenye yezi meko zilandelayo, qiniseka ukuba uxelela ugqirha wakho.
- Isifo seswekile (iswekile ephezulu egazini)
- Igazi elonyukayo
- I-cholesterol ephezulu
- Ukungahambi kakuhle kwesingqisho sentliziyo okanye isifo sentliziyo
- Isifo sezintso
- Isifo semiphunga okanye amanxeba emiphungeni
- Nasiphi na isifo sengqondo
- Iimeko ezifana nokuxhuzula
- Iingcinga zokuzilimaza, iingcinga zokuzibulala, ukuba uzamile ukwenza njalo, okanye ukuba nelungu losapho lenze njalo
- Uzama ukukhulelwa okanye ukhulelwe okwangoku
- Ukuncancisa umntwana
- Ngaba ukhe waba ne-allergy kwi-lorlatinib okanye nakweyiphi na enye iyeza, ukutya, okanye idayi ngaphambili?
Ulisebenzisa njani kanye kanye eli yeza?
Ukulandela imiyalelo echanekileyo yokusebenzisa eli yeza kubaluleke kakhulu kwiziphumo.
- Sela le pilisi kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanayo yonke imihla .
- Musa ukuyityumza, ukuyityumza, okanye ukuyihlafuna ipilisi. Yiginye yonke ngamanzi.
- Ungayithatha ngaphambi okanye emva kokutya, kodwa ukuba uziva uphazamisekile esiswini, kungcono ukuyithatha kunye nokutya.
- Qhubeka usebenzisa olu nyango de ugqirha wakho akuxelele ukuba uyeke.
- Ibaluleke kakhulu:Musa ukusela ijusi yegrapefruit ngokupheleleyo ngelixa usebenzisa eli yeza.
Kuthekani ukuba idosi iphezulu kakhulu? (Ukugqithisa)
Ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, yiya kwiSebe leeNgxamiseko (ETU) elikufutshane ngoko nangoko . Okanye utsalele umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ukuba ulibele ukuthatha idosi, yithathe kwangoko xa ukhumbula. Nangona kunjalo, ukuba kungaphantsi kweeyure ezi-4 ngaphambi kokuba uthathe idosi elandelayo, yitsibe idosi oyiphosileyo. Thatha nje idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe idosi ephindwe kabini .
Amanye amayeza anokusebenza kunye nale mayeza
I-Lorlatinib liyeza elinamandla amakhulu okusebenzisana namanye amayeza. Ngoko ke, kufuneka uxelele ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini, amayeza emifuno, kunye neti zemifuno). Ingasebenzisana namayeza alandelayo:
| Ungaze uzithathe ezi kunye ne-lorlatinib. | |
|---|---|
| apalutamide, enzalutamide, mitotane, ranolazine | Amayeza anikwa abantu abanesifo somhlaza nezifo zentliziyo ezahlukeneyo |
| Imithi yokulwa nesifo sokuwa efana ne-carbamazepine, i-phenytoin, ne-phenobarbital | Amayeza okuxhuzula |
| i-rifampin, i-rifapentine | Ii-antibiotics zosulelo lweebhaktheriya ezifana nesifo sephepha |
| I-St. John's Wort | Isongezelelo semifuno yoxinzelelo |
| i-lumacaftor; i-ivacaftor | Amayeza e-Cystic Fibrosis |
| Usenokusabela kwezi zinto - buza ugqirha wakho. | |
| Ii-antibiotics | Umzekelo: i-clarithromycin |
| Izinto ezilwa nokungunda | Umzekelo: i-ketoconazole, i-itraconazole, i-fluconazole |
| Amayeza e-HIV kunye ne-hepatitis | Umzekelo: i-ritonavir, i-boceprevir |
| IiHormones kunye nolawulo lokuzalwa | Izinto ezifana neepilisi zokulawula ukukhulelwa, iipatches, iinaliti, njl. |
| Amanye amayeza | i-bosentan, i-modafinil, i-midazolam |
Izinto ekufuneka uzikhumbule xa usebenzisa amayeza
Kuqhelekile ukuba uzive ungakhululekanga ngexesha lonyango lomhlaza, njengoko kuchaphazela zombini iiseli zomhlaza kunye neeseli eziphilileyo. Kodwa ungayeki unyango de ugqirha wakho akuxelele. Yazisa ugqirha wakho ngazo naziphi na iziphumo ebezingalindelekanga.
Ukukhulelwa, ukuncancisa kunye neengcebiso zamadoda
Eli candelo libaluleke kakhulu. Nceda unikele ingqalelo.
- Kwabasetyhini: Kuphephe ukukhulelwa ngokupheleleyo ngelixa usebenzisa eli yeza. Kwakhona, kuphephe ukukhulelwa iinyanga ezi-6 emva kokuyeka ukusebenzisa eli yeza. Sebenzisa indlela yokulawula ukukhulelwa engeyiyo eyehomoni (umz., iikhondom, i-copper T). Xelela ugqirha wakho ngokukhawuleza ukuba unesikrokro sokuba ukhulelwe. Kuphephe ukuncancisa ngelixa usebenzisa eli yeza kwaye kwiintsuku ezi-7 emva kokuyeka ukusebenzisa eli yeza.
- Kwamadoda:Amadoda asebenzisa eli yeza afanele asebenzise ikhondom xa esabelana ngesondo nomfazi onokukhulelwa. Le ndlela yokuthintela ukukhulelwa kufuneka iqhubeke iinyanga ezi-3 emva kokuyeka ukusebenzisa eli yeza. Ukuba ukrokrela ukuba iqabane lakho likhulelwe, yazisa ugqirha wakho ngoko nangoko.
Iintsholongwane kunye nomkhuhlane
Eli yeza linokwenza buthathaka amasosha omzimba wakho kwaye lonyuse umngcipheko wakho wokufumana usulelo. Ke ngoko, ukuba ufumana iimpawu ezifana nomkhuhlane, umkhuhlane, umphimbo obuhlungu, okanye ukukhwehlela, musa ukuzenza unyango kwaye ufowunele ugqirha wakho ngoko nangoko ukuze akunike ingcebiso. Zama ukuhlala kude nabantu abagulayo.
Amanqanaba e-cholesterol kunye neswekile
I-Lorlatinib inokunyusa i-cholesterol yegazi (ingakumbi i-triglycerides) kunye namanqanaba eswekile egazini. Inganciphisa ne-cholesterol elungileyo (i-HDL). Ugqirha wakho uya kuzijonga rhoqo ezi zinto. Ukuba kuyimfuneko, banokucebisa utshintsho kwindlela yokutya okanye amayeza amatsha.
Utshintsho kwimpilo yengqondo
Eli yeza linokubachaphazela abanye abantu ngokwengqondo. Xelela ugqirha wakho ngoko nangoko ukuba wena okanye ilungu losapho lwakho nibona naluphi na utshintsho olulandelayo:
- Uxinzelelo olutsha okanye oluya lusiba mandundu
- Iingcinga zokuzenzakalisa
- Ixhala
- Ukulahleka kwenkumbulo
- Ukuziphatha okanye iingcinga ezingaqhelekanga, eziphazamisayo
Zeziphi iziphumo ebezingalindelekanga ezinokubonwa?
Njengalo naliphi na iyeza, i-lorlatinib inokuba nemiphumo emibi. Ezinye zezi zinokuba yingozi kwaye kufuneka zixelwe ngoko nangoko.
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
|---|---|
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe, okanye ulwimi |
| Intlungu yesifuba okanye ukuxinana | Kusenokuba ziimpawu zokuhlaselwa yintliziyo |
| Ukukhwehlela, ubunzima bokuphefumla, ukudumba komzimba (ukudumba) | Ukutyeba ngequbuliso, ukudumba kwamaqatha, izandla neenyawo |
| Iimpawu zomonakalo wesibindi | Umchamo otyheli okanye omdaka omnyama, ukutyheli kwamehlo/ulusu, iintlungu kwicala eliphezulu lasekunene lesisu |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, umphimbo obuhlungu |
| Iimpawu zokubala iiseli zegazi eziphantsi | Ubunzima bokuphefumla, ukudinwa kakhulu, ukuphelelwa ngamandla, ukuba buhlungu |
| Utshintsho lwengqondo okanye isifo sokuwa | Iimpawu zengqondo ezingasentla, ukudideka, ukuxhuzula |
| Xelela ugqirha wakho ukuba iyaqhubeka okanye iyakukhathaza. | |
| Isicaphucaphu, ukuhlanza | Uxinzelelo lwegazi olunyukileyo |
| Utshintsho lombono, umbono ofipheleyo | Amanqanaba aphezulu e-cholesterol |
| Ukungalali kakuhle okanye ukuncipha kokulala | Ukulahlekelwa yinkumbulo, ukucaphuka |
Umyalezo Wokuya Ekhaya
- Sela amayeza kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanelekileyo, nangedosi efanelekileyo. Ungaze uwaphule okanye uwatyumze ipilisi.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi, iivithamini, kunye neemveliso zezityalo ozisebenzisayo. Ingakumbi musa ukusela ijusi yegrapefruit.
- Kuphephe ukukhulelwa ngelixa usebenzisa la mayeza kwaye kangangoko ugqirha wakho ecebisa. Abafazi namadoda kufuneka baqaphele oku.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinje ngobunzima bokuphefumla, iintlungu zesifuba, ukudumba okukhulu, okanye utshintsho olukhulu kwimo yengqondo, funa ingcebiso kagqirha ngoko nangoko.
- Eli yeza lelakho kuphela. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
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