Ngaba nawe unazo ezi mpawu? Makhe sithethe nge-MALT Lymphoma!

Ngaba wakha weva ngesifo esingaqhelekanga esibizwa ngokuba yi-MALT Lymphoma? Mhlawumbi akunjalo. Kuba sinqabile kancinci, oko kuthetha ukuba asisosifo esichaphazela wonke umntu. Kodwa kulungile ukuba sazi ngaso. Kuba esi sikwaluhlobo lomhlaza. Kodwa ungoyiki, sisasazeka kancinci emzimbeni. Namhlanje, siza kuthetha ngaso ngokweenkcukacha, ngokungathi sithetha nomhlobo.

Yintoni i-MALT Lymphoma? Ngamafutshane...

Kulungile, i-MALT Lymphoma luhlobo oluncinci lweqela elikhulu lomhlaza elibizwa ngokuba yi-`non-Hodgkin lymphoma`. Ngamanye amazwi, yenye yezona ntlobo zixhaphakileyo ze-lymphomas ezikhula kancinci ezibizwa ngokuba yi-`marginal zone lymphoma`.

Esi sifo sidla ngokuchaphazela abantu abangaphezu kweminyaka engama-65 ubudala. Sixhaphake kakhulu kumadoda kunabasetyhini. Eyona nto ilungileyo kukuba oogqirha baneendlela zonyango ezinokunyanga esi sifo. Oko kukuthi, banokusifaka esi sifo "kwimeko yokuxolelwa" , okanye kwimeko yokungalali. Nangona kunjalo, kufuneka sikhumbule ukuba ngamanye amaxesha sinokuphinda sibuye.

Ziziphi iintlobo ze-MALT Lymphoma?

Kukho iintlobo ezimbini eziphambili ze-MALT lymphoma:

1. I-Gastric MALT Lymphoma: Oku kuqala esiswini sakho, oko kukuthi, esiswini. Umaleko wangaphakathi wesisu, esiwubiza ngokuba yi-'mucosa' , kulapho uqala khona. Uninzi lwexesha, olu hlobo luhlala apho luqale khona, kodwa ngamanye amaxesha lunokusasazeka kwiindawo ezingaphandle kwesisu. Olu lolona hlobo luqhelekileyo lwe-MALT lymphoma.

2. I-Malt Lymphoma engeyoyesisu: Olu hlobo lunokuchaphazela i-mucous membranes kwimiphunga yakho, amathe, i-thyroid gland, kunye nolusu . Lunokuchaphazela nezicubu ezijikeleze amehlo akho, njengemibhobho yokukrazula .

Ixhaphake kangakanani le sifo?

I-MALT lymphoma ngokwenene sisifo esingaqhelekanga. Imalunga ne-7% yazo zonke ii-non-Hodgkin lymphomas. Ukuze sikuqonde oko, ngokutsho kwe-American Cancer Society, abantu abangama-80,550 baza kufunyaniswa bene-non-Hodgkin lymphoma ngo-2023 kuphela. Oko kuthelekiswa namatyala amatsha angama-300,590 omhlaza webele. Ngoko ke ungabona ukuba oku kunqabile kangakanani.

Isasazeka ngokukhawuleza kangakanani i-MALT Lymphoma?

Eli linqaku elibalulekileyo. Esi sifo sikhula kancinci emzimbeni. Kwinqanaba lokuqala, kusenokungabikho zimpawu zibalulekileyo. Ngamanye amaxesha, i-MALT lymphoma ifunyanwa ngengozi ngelixa ivavanywa esinye isifo.

Zithini iimpawu zoku?

Iimpawu ziyahluka ngokuxhomekeke ekubeni iphi i-lymphoma. Nangona kunjalo, zonke ii-lymphomas ze-MALT ziqala ngolu hlobo:I-mucous membrane (`mucosa`). Le mucous membrane yi-membrane emanzi ejikeleze ingaphakathi lamalungu athile emzimbeni wethu.

Iimpawu zeGastric MALT Lymphoma

Oku kubangelwa sisisu, kwaye iimpawu zingabandakanya:

• Isitshiso sentliziyo kunye nokungagayi kakuhle kokutya: Njengesitshiso sentliziyo kunye nokungagayi kakuhle ukutya sonke esikwaziyo.
• Isisu esibuhlungu.
• Isicaphucaphu nokuhlanza.
• Ukutya akunancasa.
• Ukuba mncane ngaphandle kwesizathu.
• Ukopha kwamathumbu.

Iimpawu ze-Non-gastric MALT Lymphoma

Olu hlobo lunokuchaphazela amehlo, imiphunga, amathe, ulusu, kunye ne-thyroid gland.

Ukuba amehlo achaphazelekile:

• Ijwabu eligobileyo.
• Ubomvu okanye ukudumba kwamehlo.
• Ukudumba okujikeleze amehlo.
• Umbono ophindwe kabini.

Ukuba imiphunga ichaphazelekile:

• Ubunzima bokuphefumla.
• Iintlungu zesifuba.
• Ukukhohlela okanye ukukhohlela igazi.

Ukuba amathe achaphazelekile:

Ukudumba kunokubonwa:

• Iindlebe ziphambi.
• Ngaphantsi kwesilevu.
• Ngaphakathi emlonyeni.

Ukuba ulusu luchaphazelekile:

• Amabala abomvu, apinki, okanye amfusa eluswini.
• Amaqhuma eluswini.

Ukuba i-thyroid gland ichaphazelekile:

• Iimpawu ze-hypothyroidism: Ezi ziquka ukudinwa kakhulu, ulusu olomileyo, ukunyuka kobunzima obungabonakaliyo, okanye ukwanda kokuziva ubanda.
• Iqhuma elingaphambili entanyeni.

Yintoni ebangela i-MALT Lymphoma?

Kukho izizathu ezininzi eziphambili zesi sifo, kuquka usulelo lweentsholongwane okanye iintsholongwane kunye neengxaki zokuzikhusela komzimba .

• Iibhaktheriya kunye neentsholongwane:
• Usulelo oluhlala ixesha elide olubangelwa yibhaktheriya ethi `H. pylori` yeyona nto iphambili ebangela i-gastric MALT lymphoma. `H. pylori` yibhaktheriya ebangela i-gastritis kunye nezilonda esiswini.
• Ezinye iibhaktheriya, ezifana ne-'Achromobacter xylosoxidans', 'Campylobacter jejuni', 'Borrelia burgdorferi' kunye ne-'C. psittiaci', zifunyenwe zidibene neentlobo zombini ze-MALT lymphoma.
• Intsholongwane yeHepatitis C inokunxulunyaniswa ne-lymphoma ye-MALT yesisu kunye ne-non-gastric.

• Iingxaki zokuzikhusela komzimba:
• `Isifo sikaHashimoto` (imeko echaphazela i-thyroid gland) kunye `ne-Sjögren's syndrome` (isifo sikaSjögren)(Oku kubangela izinto ezifana namehlo nomlomo owomileyo) kunokubangela ezinye ii-lymphomas ze-MALT ezingezizo ezesisu.

Ziziphi izinto ezibangela umngcipheko wokuphuhlisa i-MALT Lymphoma?

Ukuba kukho umntu kusapho lwakho okhe waba ne-lymphoma, nawe usenokuba sengozini yokuba ne-MALT lymphoma. Nangona kunjalo, oku akuqhelekanga kuwo wonke umntu.

Ifunyanwa njani i-MALT Lymphoma?

Oogqirha benza iimvavanyo ezininzi ukuze baxilonge esi sifo baze babone ukuba sisasazeke kangakanani.

Uvavanyo lwegazi

Oogqirha bangenza uvavanyo lwegazi olufana nolu:

• `I-CBC (ubalo lwegazi olupheleleyo):` ijonga iintlobo zeeseli egazini.
• `LDH (lactate dehydrogenase): Oku kunokunyuka kwezinye iintlobo zomhlaza.
• `CMP (iphaneli yemetabolism epheleleyo)` (uvavanyo lwemetabolism olupheleleyo): Ijonga ukusebenza kwamalungu anjengezintso nesibindi.
• Uvavanyo lweHepatitis C.

I-Biopsy

Oogqirha banokwenza i-biopsy ngolu hlobo:

• Uvavanyo lwe-bone marrow biopsy: Ukujonga ukuba umhlaza usasazeke na kumongo wethambo.
• I-biopsy yenaliti: Iqhekeza elincinci lesicwili lithathwa kwiqhuma elirhanelekayo lize lihlolwe.

Ngamanye amaxesha, ukuba kurhanelwa ukuba kukho i-gastric MALT lymphoma, i-biopsy inokuthathwa ngexesha le -endoscopy ephezulu , equka ukufakwa kwekhamera encinci ngomlomo ukuze kuhlolwe isisu.

Uvavanyo lokufota

Olu vavanyo lunceda ekufumaneni apho i-lymphoma ikhoyo kwaye isasazeke kangakanani (inqanaba):

• `Iiskeni ze-CT ezisebenzisa ikhompyutha`.
• `Iiskeni ze-Positron emission tomography (PET)`.

Uvavanyo lwelebhu

Iingcali zonyango zisebenzisa iimvavanyo ezifana nezi ukuhlola iiseli zezicubu okanye zomhlaza:

• `Uvavanyo lwe-H. pylori`: Kuthathwa isampuli ye-biopsy ukujonga ubukho bale bhaktiriya.
• I-Flow cytometry: Uvavanyo olukhethekileyo olunceda ekuchongeni uhlobo lweeseli.

Ukuchonga inqanaba lomhlaza (kwi-gastric MALT lymphoma) (Ukubekwa komhlaza)

Oogqirha basebenzisa iindlela zokulinganisa umhlaza ukucwangcisa unyango kunye nokuqikelela iziphumo ezilindelekileyo emva konyango. Kwi-gastric MALT lymphoma, enye yezi ndlela zilandelayo ingasetyenziswa:

• Inqanaba lokuQala: Umhlaza ukwindawo engaphakathi yesisu kuphela.
• Inqanaba lesiBini: Umhlaza usasazeke kwiindawo ze-lymph ezikufutshane, kwiindawo ze-lymph ezikude, okanye kwiindawo zomzimba ezikufutshane kunye nezicubu.
• Inqanaba lesi-4:Umhlaza usasazeke kwiindawo ezininzi ze-lymph nodes, kumongo wethambo, nangaphezulu nangaphantsi kwe-diaphragm.
• Akukho nto ibizwa ngokuba yiSigaba sesiThathu se-gastric MALT lymphoma.

Iphathwa njani i-MALT Lymphoma?

Unyango luxhomekeke kwizinto ezininzi, kuquka uhlobo lwe-MALT lymphoma, unobangela wayo, kunye nenqanaba lesi sifo. Umzekelo, ezinye izifundo zibonisa ukuba i-MALT lymphoma yesisu ekwinqanaba lokuqala inokunyangeka ngokupheleleyo ngamayeza okubulala iintsholongwane, ingakumbi ukuba ibangelwa lusulelo lwe-H. pylori.

Iindlela zonyango zingabandakanya:

• `Ukulinda ngononophelo/ukubeka esweni okusebenzayo`: Oogqirha banokucebisa le ndlela kubantu abane-MALT lymphoma ekwinqanaba lokuqala abangabonisi zimpawu. Oku kuthetha ukujonga esi sifo ngaphandle konyango.
• Ii-antibiotics: Olu nyango lubulala intsholongwane i-H. pylori, ebangela i-gastric MALT lymphoma. Ezinye izifundo zibonisa ukuba ukubulala i-H. pylori kunokunyanga nesi sifo.
• Unyango ngemitha: Oogqirha banokusebenzisa unyango ngemitha ukunyanga zombini iintlobo ze-MALT lymphoma.
• Unyango lwe-antibody ye-monoclonal: Olu nyango lunokunceda abantu abane-gastric MALT lymphoma engaphenduliyo kunyango lwe-radiation okanye abo bane-non-gastric MALT lymphoma.

Ngaba i-MALT Lymphoma inganyangeka ngokupheleleyo?

Ewe, njengoko bekutshiwo ngaphambili, i-lymphoma ye-MALT yesisu ekwinqanaba lokuqala, ingakumbi leyo ibangelwa yi-H. pylori, inokunyangwa ngamayeza okubulala iintsholongwane. Kwezinye iimeko, unyango lunokubangela isifo 'sixolelwe' , oko kukuthi, silale. Nangona kunjalo, sinokubuya ('siphindaphinda').

Ithini ingxelo yokubikezela ukuba esi sifo siza kuqala?

Ungakhululeka xa usiva oku. Abantu abane-MALT lymphoma banokuphila iminyaka, nokuba esi sifo siphinda sibuye emva konyango. Oku kungenxa yokuba luhlobo olukhula kancinci.

Ingakanani izinga lokusinda?

Ngokutsho kolunye uphando, malunga ne-88% yabantu abane-MALT lymphoma basaphila emva kweminyaka emihlanu bexilongiwe. Kodwa khumbula ukuba la mazinga okusinda asekelwe kumava abanye kunye nedatha eqokelelwe ngokuhamba kwexesha. Amava akho anokwahluka. Kwezi meko, ugqirha wakho ngumntu ongcono ukukunika ulwazi.

Ngaba i-MALT Lymphoma ingathintelwa?

Enyanisweni, abaphandi bezonyango abakazazi zonke izinto ezibangela ukuba abantu babe nesi sifo. Olunye uphando lufumanise ukubaUkuphepha usulelo lwe-H. pylori kunokunciphisa umngcipheko wokuba ne-gastric MALT lymphoma.

Ndingazinyamekela njani?

Abantu abaninzi bafuna unyango oluhlala ixesha elide. Oku kuthetha ukuvavanywa rhoqo ukuze kubonwe ukuba isifo sibuyile na. Ngokwesiqhelo, kuya kufuneka uvavanywe kwaye uhlolwe rhoqo kwiinyanga ezintathu ukuya kwezintandathu ukuya kuthi ga kwiminyaka emihlanu. Emva koko, kuya kufuneka uhlolwe kanye ngonyaka.

Ndifanele ndimbone nini ugqirha?

Abantu abane-MALT lymphoma badla ngokubona oogqirha babo rhoqo. Nangona kunjalo, bona ugqirha wakho ngoko nangoko ukuba unayo:

• Ukuba une-MALT Lymphoma kwaye ubona utshintsho olutsha (olunokuba ziimpawu) emzimbeni wakho.
• Ukuba unyangwa kwaye iimpawu zakho ziya zisiba mandundu.
• Ukuba ukwimeko 'yokuxolelwa', oko kukuthi, xa isifo siphucukile, ubona utshintsho kwindlela esivakalelwa ngayo, ngokungathi isifo 'siyaphinda'.

Ndingayibuza yiphi imibuzo ugqirha wam?

Ukuba une-MALT lymphoma, ungabuza ugqirha wakho le mibuzo:

• Luhlobo luni lwe-MALT lymphoma endinayo?
• Ithini inqanaba lesifo sam?
• Ngaba ndifuna unyango?
• Ukuba ndifuna unyango, ungandicebisa ukuba ndinyangwe ngoluphi unyango?
• Ngaba kukho naziphi na iimvavanyo zeklinikhi endifanele ndiziqwalasele?

Khumbula: I-MALT Lymphoma luhlobo olungaqhelekanga lomhlaza oluchaphazela ulwelo lwamalungu ethu kunye nezinye iindawo zomzimba, uhlobo lwe-non-Hodgkin lymphoma. Ikhula kancinci, ngoko ke ayisoloko ibangela naziphi na iimpawu. Oogqirha banokuyinyanga, kwaye ngamanye amaxesha bayayinyanga. Kodwa isifo sinokubuya, ngoko unokufuna unyango olungakumbi. Ukuba unesi sifo, thetha nogqirha wakho malunga nento omawuyilindele.

Okokugqibela, umyalezo oya ekhaya

Kulungile, mandikuxelele izinto ezimbalwa ekufuneka uzikhumbule kwinto esithethe ngayo:

• I-MALT Lymphoma luhlobo lomhlaza olukhula kancinci. Musa ukoyika, kodwa qaphela.
• Kukho iintlobo ezimbini: isisu (esiswini) kunye nesingesisisu (kwezinye iindawo).
• Ibhaktheriya ethi `H. pylori` yeyona nto ibangela isifo segastritis.
• Iimpawu zixhomekeke ekubeni i-lymphoma ikuphi, kwaye kusenokwenzeka ukuba kungabikho zimpawu ekuqaleni.
• Kukho unyango, kwaye ngamanye amaxesha lunokunyangeka ngokupheleleyo, ingakumbi kwizigaba zokuqala zomhlaza wesisu.
• Esi sifo singaphinda sibuye emva kokuba siphelile, ngoko ke kufuneka uqhubeke uphantsi kweliso likagqirha.
• Ukuba unamathandabuzo okanye imibuzo, ungoyiki ukuthetha nogqirha wakho. Leyo yeyona nto ilungileyo onokuyenza.

Ndiyathemba ukuba olu lwazi luluncedo kuwe. Hlala usempilweni!

I- MALT lymphoma, i-non-Hodgkin lymphoma, umhlaza, i-gastric MALT lymphoma, i-H. pylori, iimpawu ze-lymphoma, unyango lwe-lymphoma