Sonke siyazi ukuba igazi lithwala ioksijini emizimbeni yethu. Kodwa khawucinge, kuthekani ukuba ngesizathu esithile eli gazi belingenakukwazi ukuthwala ioksijini? Umzimba wakho ubuya kuziva ngathi uyafuthanisela, akunjalo? Namhlanje sithetha ngeyeza elikhethekileyo elisetyenziswa kwimeko enzima kangaka, esongela ubomi. Igama lalo yiMethylene Blue.
Yintoni iMethylene Blue? Yintoni eyenzayo?
Ngamafutshane, iMethylene Blue liyeza elisetyenziselwa ukunyanga imeko ebizwa ngokuba yi-methemoglobinemia .
"Ngoku yintoni i-methemoglobinemia?" usenokuba uzibuza. Kwenzeka ntoni koku kukuba iproteni ephethe ioksijini egazini lethu, ebizwa ngokuba yi-hemoglobin, iyatshintsha kwaye ayikwazi ukubopha ngokufanelekileyo kwioksijini. Emva koko ukunikezelwa kweoksijini kwizicubu zomzimba kunye namalungu omzimba kuphazamiseka ngokupheleleyo. Oku kunokubangelwa kukutya iikhemikhali ezahlukeneyo, amayeza athile, okanye izizathu zemfuza. Le yimeko eyingozi kakhulu. Kulapho kunikwa khona inaliti ye-methylene blue ukunceda ioksijini ibuyele egazini.
Eyona nto ibalulekileyo kukuba oku akufani nonyango oluqhelekileyo. Lusetyenziswa esibhedlele kuphela, phantsi kweliso elibukhali loogqirha.
Ngamanye amaxesha eli yeza lingasetyenziselwa nezinye iinjongo zonyango. Ukuba unemibuzo malunga noku, kungcono ukubuza ugqirha wakho.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba usebenzise eli yeza
Ngaphambi kokuba unikwe olu gonyo, iqela lezonyango liza kukubuza imibuzo embalwa. Kubalulekile ukuba ukhuseleke ukubanika ulwazi oluchanekileyo. Qiniseka ukuba ubaxelela ukuba unayo nayiphi na kwezi meko zilandelayo:
- Ukunganyamezelani ne-methylene blue okanye amanye amayeza: Ukuba ukhe waba ne-allergy kumayeza anjenge-methylene blue, i-phenothiazines, i-thiazide diuretics, okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukunqongophala kwe-G6PD: Ukuba unesifo semfuza esibizwa ngokuba yi -glucose-6-phosphate dehydrogenase (G6PD) . Oku kukungabikho kwee-enzyme ezinxulumene neeseli zegazi. Ukunika i-methylene blue kubantu abanale meko kunokuba yingozi.
- Ityhefu yeCyanide: Ukuba ungumntu onyangwa ityhefu yeCyanide.
- Isifo Sezintso: Ukuba unesifo sezintso.
- Ukukhulelwa okanye ukuzama ukukhulelwa: Ukuba ukhulelwe okanye unethemba lokukhulelwa, ngokuqinisekileyo kufuneka uxelele ugqirha wakho.
- Ukuba uncancisa:Kwakhona xelela ugqirha ukuba ungumama oncancisayo.
Ungayisebenzisa njani le yeza?
Eli asiloyeza onokulithatha uye nalo ekhaya. Liyeza lokujova emthanjeni . Linikwa kuphela yingcali yezempilo, njengogqirha okanye umongikazi oqeqeshiweyo, esibhedlele okanye eklinikhi.
Ngaba ninika abantwana oku?
Ewe, eli yeza linokunikwa abantwana ukuba kuyimfuneko. Nangona kunjalo, lifuna unonophelo olukhethekileyo. Ungathetha nogqirha wezingane zakho ukuze ufumane iinkcukacha ngalo mba.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Oku kunikwa esibhedlele, ngoko ke amathuba okuba oku kwenzeke mancinci. Nangona kunjalo, ukuba ucinga ukuba usele amayeza amaninzi kakhulu, kufuneka wazise iqela lezonyango lesibhedlele ngoko nangoko. Ngokubanzi, xa kukho ityhefu, kufuneka utsalele umnxeba iZiko loLwazi lweeTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) yesibhedlele.
Amanye amayeza anokusebenzisana nalo mayeza (Ukusebenzisana kwamayeza)
Le yinxalenye ebaluleke kakhulu. I-Methylene blue sisiyobisi esinokungasebenzi kakuhle kwamanye amayeza. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (abhalwe ngabanye oogqirha, athengwe kwikhemesti, amayeza esintu, iivithamini, izongezo - yonke into).
I-Methylene blue akufanele inikwe umntu othatha la mayeza alandelayo:
| Uhlobo lweziyobisi | Imizekelo |
|---|---|
| Amanye amayeza okudakumba okanye ukuxhalaba | I-Bupropion, i-Clomipramine, i-Doxepin, i-Duloxetine, i-Fluoxetine, i-Mirtazapine, i-Trazodone |
| Amayeza akwiqela le-MAOI (i-monoamine oxidase inhibitors) | Iziyobisi ezifana neMarplan, iNardil, iParnate, iRasagiline, iSelegiline |
| Amanye amayeza kunye nezongezo | I-Milnacipran, i-Tryptophan, i-St. John's wort (isongezo semifuno) |
Olu luhlu aluphelelanga, ngoko ke kubalulekile ukuxelela ugqirha wakho ngayo yonke into oyithathayo. Kwakhona, mxelele ukuba uyatshaya, usela utywala, okanye usebenzisa ezinye iziyobisi.
Zithini iziphumo ebezingalindelekanga ezinokubakho xa usebenzisa amayeza?
Njengalo naliphi na iyeza, i-methylene blue inokubangela iziphumo ebezingalindelekanga. Ezinye zezi zimbi kakhulu, ezinye azimbi kangako. Iqela lakho lezonyango liza kukujonga ngokusondeleyo ngelixa unikwa iyeza. Kodwa kulungile ukuqaphela ezi mpawu.
| Imiphumela | Inkcazo |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha ngoko nangoko | |
| Iintlungu zesifuba | Intlungu evakala ngathi intliziyo iyacinezelwa, ngathi iyafuthaniselwa. |
| Ukudideka | Kunzima ukucinga ukuba uphi, nini, okanye ungubani. |
| Isiyezi | Ukuziva ulahlekelwa lulawulo lomzimba wakho, ngokungathi ihlabathi liyakujikeleza. |
| Intloko ebuhlungu kakhulu | Intloko ebuhlungu enganyamezelekiyo ngequbuliso. |
| Ukubila okwandileyo | Ukubila kakhulu ngaphandle kwesizathu esithile. |
| Intlungu yesisu | Intlungu yesisu eqatha nengapheliyo. |
| Iziphumo ebezingalindelekanga ezingaqhelekanga, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Umchamo oluhlaza okwesibhakabhaka/oluhlaza kunye nendle | Oku kulindelekile. Oku kwenzeka ngenxa yombala weyeza. Akukho nto ifanele ixhalabise ngayo. |
| Ulusu oluluhlaza okwesibhakabhaka | Ngamanye amaxesha ulusu lunokutshintsha lube luhlaza okwesibhakabhaka. |
| Isicaphucaphu nokuhlanza | Isicaphucaphu okanye ukuhlanza kunokwenzeka ngexesha okanye emva kokuba iyeza linikwe. |
Umyalezo Wokuya Ekhaya
- I-Methylene Blue liyeza elisindisa ubomi elinikezelwa ukunyanga imeko enzima ebizwa ngokuba yi-methemoglobinemia , apho igazi lingakwaziyo ukuthwala ioksijini.
- Oku kunikwa kuphela njengenaliti emthanjeni esibhedlele, phantsi kweliso likagqirha. Asiloyeza lokuya nalo ekhaya.
- Kubalulekile ukwazisa ugqirha wakho malunga nazo zonke ezinye iziyobisi ozisebenzisayo, ingakumbi amayeza okudakumba, kunye nazo naziphi na iimeko zempilo onazo, ezinje ngokungabikho kwe-G6PD .
- Kuqhelekile ukuba iyeza libangele umchamo oluhlaza okwesibhakabhaka/oluhlaza kunye nendle. Nangona kunjalo, ukuba ufumana iimpawu ezifana nentlungu yesifuba, ukudideka, okanye intloko ebuhlungu, yazisa iqela lakho lezonyango ngoko nangoko.
- Ukuba unemibuzo malunga nale mithi okanye imeko yakho, nceda ungathandabuzi ukubuza ugqirha wakho.
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