Ngaba inkqubo yemithambo-luvo kunye nenkqubo yomzimba yokuzikhusela zizihlobo? Masithethe nge-neuroimmunology ngokulula!

Ngaba wakha wazibuza ukuba iinkqubo ezimbini ezimangalisayo ngaphakathi emizimbeni yethu, inkqubo yemithambo-luvo (ewe, loo seti yobuchopho, intambo yomgogodla, kunye nemithambo-luvo!) kunye nenkqubo yomzimba yokuzikhusela (iseti esebenza njengomkhosi wokuzikhusela womzimba wethu!) zisebenza njani kunye? Abantu abaninzi babecinga ukuba ezi zimbini zahlukene kwaye zisebenza ngokuchaseneyo. Kodwa namhlanje, kwesi sihloko sibizwa ngokuba yi-'Neuroimmunology', siyaqonda ukuba kukho unxibelelwano olukhulu phakathi kwezi zimbini kunokuba besicinga. Zisebenza njengabahlobo ababini abasenyongweni!

Yintoni kanye kanye i-neuroimmunology?

Ngamafutshane, i-'Neuroimmunology' lisebe elikhethekileyo lezonyango. Kule nto, sifunda nge-'Neuroscience', efunda ' iNkqubo yeNervous' , kunye ne-'Immune System', efunda ' iNkqubo yeMzimba', kunye nendlela ezi nkqubo zimbini ezisebenzisana ngayo ukuxhasa ukukhula kwemizimba yethu, impilo (yiloo nto i-'Homeostasis' ithetha ngayo), kunye nezifo ezahlukeneyo kunye nokwenzakala.

Izazinzulu bezisoloko zicinga ukuba ezi nkqubo zimbini zahlukene ngokupheleleyo kwaye azixhomekekanga kwenye. Kodwa uphando olutsha lubonise ukuba oku akuyonyani. Enyanisweni, ezi nkqubo zimbini zihlala zinxibelelana ngeendlela ezinzima kakhulu.

Cinga ngale ndlela. Inkqubo yakho yemithambo-luvo, ingakumbi ingqondo yakho, ihlala ithetha neeseli zakho zomzimba. Ingqondo ithumela imiqondiso kwiiseli zomzimba, isithi, "Kulungile, ngoku masenze ukudumba apho." Ukudumba yinkqubo apho inkqubo yomzimba yomzimba isebenza khona kwaye isikhusela kwizinto eziyingozi ezifana neentsholongwane ezingena emizimbeni yethu. Cinga ngako, ngaphandle kwale nkqubo ye-neuroimmunological, imizimba yethu ibingayi kuba nakhuseleko, akunjalo? Kufana nemikhosi yokhuseleko yelizwe lethu efumana imiyalelo evela kwikomkhulu.

"Nangona ngaphambili kwakucingwa ukuba zisebenza ngokwahlukeneyo, inkqubo yemithambo-luvo kunye nenkqubo yomzimba yokuzikhusela zifana nabahlobo ababini abasenyongweni abathetha rhoqo kwaye besebenza kunye!"

Ngoko ke, zithini izifo ze-Neuroimmune?

Ngoku uyaqonda ukuba inkqubo yemithambo-luvo kunye nenkqubo yomzimba yokuzikhusela zibaluleke kangakanani, kwaye zisebenza njani kunye. Nangona kunjalo, ngamanye amaxesha obu buhlobo bunokuba yingozi kancinci. Kulapho ke izifo ze-neuroimmune ziqala khona.

Nantsi indlela esebenza ngayo: Umsebenzi ophambili wenkqubo yethu yokuzikhusela kukuzikhusela kwizinto ezinobungozi ezifana neentsholongwane, iibhaktheriya, kunye neentsholongwane ezingena emizimbeni yethu. Kodwa ngamanye amaxesha, le nkqubo yokuzikhusela ifumana imiyalelo engalunganga . Okanye, iyabhideka kancinci.Okwenzekayo ke kukuba inkqubo yethu yomzimba yokuzikhusela iphosisa ngokuyiphutha ukuba iyazichonga ezinye iindawo ezisempilweni zenkqubo yethu yemithambo-luvo (oko kukuthi, ingqondo, umqolo, okanye imithambo-luvo) "njengotshaba" ize iqale ukuzihlasela. Kufana nonogada endlwini yethu ocinga ukuba singamasela aze asihlasele.

Xa inkqubo yomzimba yokuzikhusela ihlasela inkqubo yethu yemithambo-luvo esempilweni ngale ndlela, iimpawu ezahlukeneyo ziqala ukubonakala ezichaphazela ukusebenza kwenkqubo yemithambo-luvo.

Ziziphi iintlobo zezifo ezikhoyo?

Kukho iintlobo ezahlukeneyo zezifo ezibangelwa kukungasebenzi kakuhle kwengqondo. Usenokuba ukhe weva ngezinye zazo. Olu luhlu nje lwezinye, njengoko eli nqaku linokuba lide kakhulu ukuba lingachazwa zonke. Ngoko ke, qwalasela ezi njengemizekelo:

• ``I-Acute Demyelinating Encephalomyelitis (ADEM)''
• ``I-Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)''
• ``I-Acute Inflammatory Demyelinating Polyneuropathy (AIDP)''
• `I-Autoimmune/Paraneoplastic Encephalitis`
• ``Isifo esinxulumene ne-Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease (MOGAD)''
• `Isifo se-Multiple Sclerosis (MS)` - Oku kwaziwa kakuhle, akunjalo?
• I-Neurosarcoidosis kunye nezinye izifo ze-autoimmune ezibangelwa yi-CNS
• ``Isifo se-Neuromyelitis Optica Spectrum Disorder (NMOSD)''
• I-Optic Neuritis
• I-Myelitis eguquguqukayo

Isifo ngasinye sahlukile, kwaye asinguye wonke umntu ofumana iimpawu ezifanayo.

Zingaba yintoni iimpawu zezi zifo?

Iimpawu zezifo ze-neuroimmune zahlukile kakhulu. Oku kungenxa yokuba iimpawu ziyahluka ngokuxhomekeke ekubeni leliphi icala lenkqubo yemithambo-luvo elihlasela inkqubo yokuzikhusela komzimba. Nangona kunjalo, ezinye zeempawu eziqhelekileyo ziquka:

• Iingxaki zomchamo kunye namathumbu: Usenokuba nobunzima bokulawula umchamo wakho, okanye usenokuba nezinto ezifana nokuqhinwa.
• Ukuphazamiseka kwengqondo: Oku kuthetha ubunzima bokucinga, ukukhumbula ulwazi, nokufunda izinto ezintsha. Ngamanye amaxesha, nezinto eziqhelekileyo zinokulibaleka.
• Ukudinwa okungapheliyo: Ukuziva udiniwe kakhulu kwaye udiniwe nokuba ulala kangakanani na.
• Ukutshintsha kwemo yengqondo: Izinto ezifana nokuziva ulusizi ngequbuliso, unomsindo, okanye uxhalabile.
• Ubuthathaka bemisipha: Usenokuziva ngathi amalungu akho ayaphela amandla kwaye kunokuba nzima ukuphakamisa iintsimbi.
• Utshintsho kwimvakalelo: Amanye amalungu omzimba asenokuziva ngathi aziva ngathi aziva, arhawuzelela, okanye azive ngathi azivanga kakuhle kwezinye iindawo.
• Ubunzima bokuthetha: Intetho engacacanga, ubunzima bokuthetha.
• Ingxaki ngokulinganisela nokuhamba: Usenokuziva ungaqinisekanga xa uhamba kwaye usenokuziva ngathi uza kuwa.
• Utshintsho embonweni: Usenokubona izinto ezingaqhelekanga ngequbuliso, ubone izinto ezimbini, okanye uva iintlungu emehlweni.

Into ebalulekileyo kukuba ukuba unenye okanye ngaphezulu kwezi mpawu, akuthethi ukuba unesifo se-neuroimmune. Nangona kunjalo, ukuba ezi mpawu ziyaqhubeka, kungcono ukubona ugqirha ukuze akunike ingcebiso.

Zixhaphake kangakanani okanye aziqhelekanga kangakanani ezi meko?

Oku kunzima ukukutsho ngaxeshanye. Ngenxa yokuba kukho iintlobo ezininzi zezifo ze-neuroimmune, azifani zonke. Ezinye izifo (ezifana ne-'Multiple Sclerosis') zixhaphakile kakhulu. Kodwa ezinye izifo zinqabile kakhulu. Ngenxa yoko, akunakwenzeka ukuthi ngandlela thile "ezi zifo zixhaphakile" okanye "zinqabile".

Ngubani lo gqirha wezifo zengqondo? Wenza ntoni?

I-'Neuroimmunology' ngugqirha ofunde nzulu waza wafumana uqeqesho olukhethekileyo kweli candelo likhethekileyo elibizwa ngokuba yi-neuroimmunology.

Aba gqirha basinceda 'sixilonge' , 'sinyange', kwaye 'silawule' izifo ezichaphazela inkqubo yemithambo-luvo kunye nenkqubo yomzimba yokuzikhusela. Basebenza nogqirha wakho wosapho okanye ezinye iingcali ukukunceda ufumane ezona ndlela zonyango zilungileyo kuwe. Bakwaqhuba uphando olutsha ngezi zifo kwaye benza iimvavanyo zeklinikhi ukuze bafumane unyango olutsha.

Ziziphi iindlela zonyango zezi zifo?

Unyango lwezifo ze-neuroimmune luyahluka ukusuka kwisigulana ukuya kwisigulana nakwisifo ngasinye. Ugqirha wakho uya kugqiba ngonyango oluya kuxhomekeke kuhlobo lwesifo onaso kunye neempawu zakho. Nazi ezinye zeendlela zonyango ezisetyenziswa kakhulu:

• Amayeza: Kukho iintlobo ngeentlobo zamayeza anokusetyenziswa ukulawula ukungasebenzi kakuhle kwenkqubo yomzimba yokuzikhusela nokunciphisa iimpawu.
• Iindlela ezahlukeneyo zonyango:
• Unyango lokuthetha: Kwabo banengxaki yokuthetha.
• Unyango lomzimba: Yomeleza izihlunu kwaye inciphise ubunzima bokuhamba.
• Unyango lomsebenzi: Lubonelela ngeengcebiso noqeqesho ukuze lukuncede wenze imisebenzi yemihla ngemihla ngokulula.
• Izixhobo zokuncedisa: Abanye abantu banokufuna ukusebenzisa izinto ezifana nesitulo sabakhubazekileyo okanye isixhobo sokuhamba xa benengxaki yokuhamba.
• Utshintsho kwindlela yokuphila:
• Ukuzilolonga rhoqo.
• Ukutya ukutya okunesondlo.
• Lala kamnandi.
• Ukulawula uxinzelelo.
• Ukulawula ezinye izifo:Ngamanye amaxesha, ezinye iimeko zempilo ezifana 'noxinzelelo lwegazi oluphezulu', 'i-cholesterol ephezulu', 'isifo seswekile' zinokwenza ezi zifo zibe mandundu. Ngoko ke, kubaluleke kakhulu ukulawula ezo zifo kakuhle ukuba unazo.

Ugqirha wakho uza kukufundisa ngonyango olulungele wena, izinto ezilungileyo nezingalunganga, kunye nemiphumo emibi enokubakho yonyango. Ungaze wenze nantoni na ovakalelwa kukuba uyayenza ngaphandle kokubonisana nogqirha kuqala.

Okokugqibela, ezona zinto zibalulekileyo ekufuneka uzikhumbule

Kulungile, ngoko ke ndiyathemba ukuba ngoku uyiqonda ngcono le sihloko sixoxe ngaso namhlanje, `iNeuroimmunology.` Nangona le yingongoma enzima kancinci, ndizamile ukuyichaza ngokulula kangangoko kunokwenzeka kuwe.

Khumbula, inkqubo yethu yemithambo-luvo kunye nenkqubo yomzimba yokuzikhusela azizizo iinkqubo ezimbini ezahlukeneyo. Zifana nabahlobo abasoloko besebenzisana kwaye bencedana.

Isayensi ye-"Neuroimmunology" iphonononga ngakumbi olu nxibelelwano lunomdla. Olu phando lunokunceda ekuboneleleni ngonyango olungcono kubantu abanezi zifo, mhlawumbi nokubathintela ekukhuleni kwazo kwixesha elizayo.

Ukuba uneengxaki ezifana nezi zikhankanyiweyo kweli nqaku, ungoyiki kwaye ungalibazisi ukuya kugqirha. Okukhona isifo sifunyanwa ngokukhawuleza, kokukhona unyango lunokuqala ngokukhawuleza. Oku kuya kukunika isiqabu esikhulu.

I- Neuroimmunology, inkqubo yeemvakalelo, inkqubo yomzimba yokuzikhusela, izifo zokuzikhusela komzimba, izifo zobuchopho, izifo zeemvakalelo