Xa sibona umntu kusapho lwethu, mhlawumbi umama, utata, umakhulu, okanye utatomkhulu wethu othandekayo, elibale izinto kancinci kancinci njengoko ekhula, siziva soyika kwaye sibuhlungu, akunjalo? Kukho amaxesha apho sizibuza, "Ngaba oku kukuqala kwesifo se-Alzheimer?" Lo ngumbuzo abantu abaninzi abanawo. Ngoko ke namhlanje, masithethe ngokulula nangobubele ngesifo se-Alzheimer, malunga nezizathu ezisandula ukufunyanwa ezisichaphazelayo, kwaye okona kubaluleke kakhulu, malunga nezinto esinokuzenza ukuzikhusela kule meko.
Yintoni kanye kanye isifo sika-Alzheimer?
Ngamafutshane, isifo sika-Alzheimer asisosifo sobusuku. Sisifo esikhula kancinci kakhulu, kwiminyaka emininzi, ngaphakathi kwengqondo yethu. Ngamanye amaxesha, utshintsho engqondweni lunokuqala kwiminyaka eli-10 ngaphambi kokuba uqale ukuqaphela iimpawu.
Ngokutsho kwezazinzulu, esona sizathu siphambili soku kukuqokelelana okungeyomfuneko kweentlobo ezimbini zeeproteni phakathi kweeseli zobuchopho.
1. Ii-Beta-amyloid plaques: Ezi zifana 'namahlwili' eeproteni aqokelelana phakathi kweeseli zobuchopho.
2. IiTau tangles: Ezi ziiproteni 'tangles' ezakha ngaphakathi kwiiseli zobuchopho.
Cinga ngale ndlela: iiseli zethu zengqondo zifana nabantu abafuna ukuthetha omnye nomnye nokutshintshiselana ngolwazi. Ezi protein clumps kunye ne-tangles zithintela ezo seli ukuba zinganxibelelani. Ekuhambeni kwexesha, ezi seli zengqondo ziyafa kancinci kancinci. Kulapho amandla ethu okucinga, ukukhumbula, kunye nokuqiqa ehla khona.
Ziziphi izinto ezibangela umngcipheko ezichaphazela oku?
Kukho izinto ezithile ezibangela uphuhliso lwesifo sika-Alzheimer. Ezinye zezi zinto sinokuzilawula, ezinye asinakukwazi ukuzilawula.
Eyona nto ibalulekileyo kukuthetha nogqirha wakho wosapho ngale nto uze ufumane ingcebiso ukuba ufumanisa ukuba unale mingcipheko.
| Into enobungozi | Ingcaciso elula |
|---|---|
| Ukwaluphala | Umngcipheko uyanda emva kweminyaka engama-65. Kodwa oku akuyonto iqhelekileyo yokwaluphala. |
| Imbali yosapho (i-genetics) | Ukuba kukho umntu kusapho lwakho (umama, utata, umntakwenu) okhe waba nesi sifo, nawe usemngciphekweni omkhulu kancinci. |
| Igazi elonyukayo | Uxinzelelo lwegazi oluphezulu olungalawulwayo lungonakalisa ingqondo. |
| I-cholesterol ephezulu | Oku kuchaphazela nengqondo ngemithambo yegazi. |
| Isifo seswekile | Isifo seswekile esingalawulwayo sinyusa kakhulu umngcipheko we-Alzheimer's. |
| Ukutshaya | Iityhefu ezikwicuba ziyingozi ngqo kwimpilo yengqondo. |
| Ukutyeba kakhulu | Utshintsho emzimbeni olubangelwa bubunzima bomzimba obugqithisileyo luchaphazela nengqondo. |
Ngoku izazinzulu zithi isifo sika-Alzheimer, njengezinye zezi zinto zinobungozi, sikwaphenjelelwa zezinye iinkqubo ezimbini emizimbeni yethu: uxinzelelo lwe-oxidative kunye nokuvuvukala okungapheliyo .
Yintoni i-Oxidative Stress?
Musa ukoyika xa usiva eli gama. Lilula kakhulu.
Iiseli zomzimba wethu zihlala zivelisa amasuntswana ayingozi abizwa ngokuba zii-free radicals . Zikwangeniswa emzimbeni ngenxa yezinto zangaphandle ezifana nokutshaya kunye nongcoliseko lomoya.
Nangona kunjalo, imizimba yethu ikwanamajoni alungileyo atshabalalisa la masuntswana ayingozi. Siwabiza ngokuba zii-antioxidants .
Uxinzelelo lwe-oxidative luba xa inani lee-free radicals lidlula inani lee-antioxidants. Kufana nesikali esijikiswa ecaleni. Oku kungalingani konakalisa iiseli zethu kwaye kukhawulezisa inkqubo yokwaluphala. Oku kuvula umnyango wezifo ezininzi, kungekuphela nje i-Alzheimer's, kodwa ne-Parkinson's, umhlaza, kunye nesifo sentliziyo.
Okumangalisayo kukuba, iproteni ebizwa ngokuba yi-beta-amyloid ebangela i-Alzheimer's ikwasebenza njenge-antioxidant. Kodwa xa uxinzelelo lwe-oxidative lusanda, ikopi ephosakeleyo neyingozi yaloo proteni inye iqala ukwakheka. Yiyo leyo eqokelelana engqondweni ize ibangele iingxaki.
Ukuvuvukala kuyichaphazela njani umzimba?
Ukudumba ngokwenene yindlela yokuzikhusela emzimbeni wethu. Khawuthelekelele ukuba usika isandla sakho size sibe bomvu, sidumbe, sishushu, akunjalo? Kukudumba oko. Yinto eyenziwa ngumzimba ukulwa neentsholongwane nokuphilisa inxeba.
Nangona kunjalo, ukuba oku kuvutha kuyaqhubeka, oko kukuthi, ukuba kuba kukuvutha okungapheliyo , kufana nonogada endlwini ohlala ephazamisa indlu aze abangele umonakalo kwindlu ngokwayo.
Oku kwenzeka kwisifo sika-Alzheimer. Oku kuvutha okungapheliyo engqondweni kubangela ukuba ii-beta-amyloid plaques kunye ne-tau tangles esithethe ngazo ngaphambili zibe mandundu. Oku kwandisa umonakalo kwiiseli zengqondo.
Singenza ntoni ukulawula ezi meko?
Iindaba ezimnandi zezokuba singalawula uxinzelelo lwe-oxidative kunye nokudumba okungapheliyo ngokwenza utshintsho kwindlela esiphila ngayo, oko kuthetha ukuba sinamandla amaninzi ezandleni zethu okunciphisa umngcipheko we-Alzheimer's.
| Kwenziwe ntoni | Kutheni kwaye kwenziwa njani oko? |
|---|---|
| Kuphephe ukutshaya. | Iicuba ziindawo zokugcina ii-free radicals. Ukuyeka ukutshaya kunokunciphisa ngokuthe ngqo umngcipheko we-Alzheimer's. |
| Nciphisa utywala. | Ukusetyenziswa kakhulu kotywala kuyakhawulezisa ukuguga kwengqondo. Ukusela okuphakathi kuchazwa njengesiselo esinye (umz., ibhotile yebhiya) ngosuku kubafazi kunye nezimbini kumadoda. |
| Ukutya okunempilo | Yitya iziqhamo, imifuno (ingakumbi imifuno eluhlaza enamagqabi), kunye nokutya okutyebileyo kwi-antioxidants (iivithamini C kunye no-E). Iintlanzi ezinamafutha ezifana ne-salmon kunye ne-olive oil zinciphisa ukudumba. Kuphephe ukutya okuqhotsiweyo nokucutshungulwayo. |
| Zama iiprobiotics. | Iibhaktheriya ezilungileyo emathunjini ethu nazo zibalulekile kwimpilo yengqondo. Faka izinto ezifana neyogathi kunye nobisi lwenkomo ekutyeni kwakho. |
| Ukuzilolonga. | Zilolonge iintsuku ezi-3 ukuya kwezi-5 ngeveki imizuzu engama-20-30. Nokuba uhamba ngokukhawuleza okanye ulima igadi, ngumthambo olungileyo. Musa ukuzibhokoxa kakhulu, kuba oku kunokunyusa imveliso yee-free radicals. |
| Gcina ubunzima bakho busempilweni. | Ukutyeba kakhulu kubangela ukudumba emzimbeni wonke. Kukwachaphazela nengqondo. |
| Nciphisa uxinzelelo. | Uxinzelelo luyimbangela enkulu yokudumba kunye noxinzelelo lwe-oxidative. Izinto ezifana neyoga, ukucamngca, kunye nokuzilolonga ngokuphefumla nzulu zinokunceda. |
| Lala ngokwaneleyo. | Ingqondo isusa ezo plaque ze-beta-amyloid ezingafunekiyo xa silele. Ukulala kakuhle yonke imihla kubalulekile. |
Umyalezo Wokuya Ekhaya
- Isifo sika-Alzheimer asikokulibala nje izinto njengoko sikhula, sisiphumo sothotho lweenguqu ezinzima ezenzeka engqondweni.
- Uxinzelelo lwe-oxidative kunye nokudumba okungapheliyo zezona zinto zimbini zibangela esi sifo.
- Indlela ophila ngayo yeyona ndlela ilungileyo yokukukhusela. Ungawunciphisa kakhulu umngcipheko wakho ngokutya ukutya okunempilo, ukuzilolonga, ukuphepha ukutshaya, ukulawula uxinzelelo, nokulala ngokwaneleyo.
- Ukuba wena okanye umntu omthandayo uneengxaki zokukhumbula, nceda ungoyiki okanye ungabi neentloni ukuthetha nogqirha wakho . Kubaluleke kakhulu ukufuna ingcebiso kwangethuba.
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