Yintoni i-norepinephrine? Masithethe ngayo ngokulula!

Ngaba wakha wazibuza ukuba kwenzeka ntoni ngaphakathi emzimbeni wakho xa ngequbuliso usoyika okanye uxhalabile? Okanye zeziphi izinto ezikugcina uphaphile kwaye uchwayitile? Kukho ikhemikhali encinci kodwa ebaluleke kakhulu eveliswa emzimbeni wethu enxulumene nazo zonke ezi zinto. Yi-norepinephrine, eyaziwa ngokuba yi-noradrenaline ngabanye. Makhe sibone ukuba oku kubaluleke kangakanani emzimbeni wethu.

Yintoni kanye kanye i-norepinephrine?

Ngamafutshane, le norepinephrine ifana nomntu owenza izinto ezimbini emzimbeni wethu: Enye kukusebenza njenge -neurotransmitter . Enye kukusebenza njenge -hormone .

Cinga ngale ndlela: i-neurotransmitter ifana nomthunywa. Inceda iiseli zethu zemithambo-luvo ukuba zinxibelelane. Ithwala imiyalezo esuka kwiseli enye yemithambo-luvo iye kwenye, okanye ukusuka kwiseli yemisipha ukuya kwiseli yendlala. Kufana nokuhambisa ileta evela eposini.

Njengehomoni, i-norepinephrine iveliswa ziindlala zethu ze-adrenal . Ezi zibekwe phezu kwezintso zethu, njengesiciko. Ezi homoni zikhutshwa ngqo egazini lethu kwaye zihamba emzimbeni wonke ukuze zenze imisebenzi eyahlukeneyo.

Njenge-neurotransmitter, i-norepinephrine iveliswa kwenye ikhemikhali ebizwa ngokuba yi-dopamine . Oku kuveliswa ikakhulu ziiseli zemithambo-luvo kwisiseko sobuchopho nakufutshane nomthambo womqolo.

I-Norepinephrine yinxalenye yenkqubo yethu yeemvakalelo enovelwano . Yile nto ilawula impendulo yomzimba wethu "yokulwa okanye ukubaleka" ngamaxesha ongxamiseko, oko kukuthi, ngamaxesha omngcipheko. Ngokwezonyango, oku kubizwa ngokuba yimpendulo yoxinzelelo olukhawulezileyo .

Yintoni eyenziwa yi-norepinephrine emzimbeni?

Nazi ezinye zezinto eziphambili ezenziwa yi-norepinephrine njenge-neurotransmitter engqondweni yethu nakwi-spinal cord:

• Iyandisa ingqalelo yethu, ukuphaphama, kunye nomdla. Ikunceda uhlale ugxile xa ufunda okanye usenza umsebenzi obalulekileyo.
• Iyanciphisa imithambo yegazi. Oku kunceda ekulawuleni uxinzelelo lwethu lwegazi ngamaxesha oxinzelelo.
• Ikwachaphazela umjikelo wethu wokulala nokuvuka, isimo sengqondo kunye nenkumbulo.

Ziziphi izinto ezichaphazela ukukhululwa kwe-norepinephrine?

Njengehomoni, uxinzelelo lolona sizathu siphambili sokuba amadlala ethu e-adrenal akhuphe i-norepinephrine. Olu hlobo lokuphendula lubangela utshintsho oluninzi emizimbeni yethu. Oku sikubiza ngokuba yimpendulo "yokulwa okanye ukubaleka" esiyikhankanyileyo ngaphambili.

Ithini le mpendulo "yokulwa okanye ukubaleka"?

Ngamafutshane, le yindlela umzimba wethu ozilungiselela ngayo ukujongana nengozi okanye uloyiko olungalindelekanga. Khawuthelekelele uhamba esitalatweni uze ngequbuliso inja eyoyikekayo ifike ikusukele. Emva koko kufuneka ulwe nenja okanye ubaleke kuyo. Oku kwenzeka ngaphakathi emzimbeni wethu kwimeko enjalo. Mhlawumbi ukuba ngequbuliso kufuneka uthethe phambi kwabantu abaninzi, umzimba wakho unokuba nolu hlobo lokusabela.

Ngexesha lokuphendula "ngokulwa okanye ukubaleka", ingqondo yakho yeyokuqala ukuqaphela ukuba kukho ingozi. Emva koko, imithambo-luvo ekwi -hypothalamus yengqondo yakho ithumela umyalezo ecaleni komqolo ukuya kuwo wonke umzimba wakho. Lo myalezo uthwalwa yi-neurotransmitter esithethe ngayo ebizwa ngokuba yi-norepinephrine. Le norepinephrine iya kumalungu kunye nezicubu ezilandelayo, nto leyo ebangela ezi mpendulo zikhawulezayo:

• Amehlo: Iimbombo zamehlo ziba nkulu, nto leyo evumela ukukhanya okungakumbi ukuba kungene kwaye isilwanyana sibone ngcono indawo esingqongileyo ukuze siphephe ingozi.
• Ulusu: Ulusu luba mhlophe. Okwenzekayo kukuba imithambo yegazi ithunyelwa umyalezo wokuthumela igazi kwiindawo ezifuna ioksijini engaphezulu, oko kukuthi, kwimisipha. Kulapho ufumana khona amandla okulwa okanye okubaleka.
• Intliziyo: Intliziyo iqala ukubetha ngamandla nangakumbi. Eli gazi lingaphezulu komoya-mpilo lithunyelwa kwiindawo ezifuna amandla, njengemisipha. Uxinzelelo lwegazi nalo luyanda ngeli xesha.
• Izihlunu: Izihlunu zifumana igazi neoksijini engaphezulu, nto leyo evumela ukuba zisebenze ngamandla nangesantya esingaphezulu.
• Isibindi: I-Glycogen egcinwe esibindini iguqulwa ibe yi -glucose, nto leyo enika amandla angakumbi.
• Indlela yokuphefumla: Ukuphefumla kuya nzulu kwaye kukhawuleza. Imigudu yomoya iyavuleka, ivumela ioksijini engaphezulu ukuba ingene egazini, ize ke ihambe iye kwimisipha.

Le neurotransmitter, i-norepinephrine, ikwaya kwi-adrenal gland yethu. Emva koko ikhupha iihomoni i-adrenaline (i-epinephrine) kunye ne-noradrenaline (i-norepinephrine). Ezi homoni zihamba ngegazi emzimbeni wonke ziye emehlweni, entliziyweni, kwindlela yokuphefumla, kwimithambo yegazi eluswini, zize zibuyele kwi-adrenal gland. "Umyalezo" onikwa ezo zitho kukusebenza ngale ndlela ude ubaleke engozini.

Le yinkcazo elula kakhulu yempendulo "yokulwa okanye ukubaleka". Ezinye iindawo zenkqubo yethu yemithambo-luvo, ezinye iinkqubo zamalungu omzimba, iihomoni, kunye nee-neurotransmitters nazo ziyabandakanyeka.

Isetyenziswa njani i-norepinephrine njengeyeza?

I-Norepinephrine njengeyeza isetyenziswa kwiimeko ezilinganiselweyo, zexesha elifutshane ukunyusa nokugcina uxinzelelo lwegazi xa uxinzelelo lwegazi oluphantsi luyingxaki. Oku kunokwenzeka kwiimeko ezifana nezi:

• Iimeko ezifana nokubanjwa kwentliziyo
• Xa kwenziwa i-anesthesia yomgogodla
• I-Septicemia, imeko yokutyhefa igazi
• Iingxaki zotofelo-gazi
• Iimpendulo ezingalunganga kwamanye amayeza (Iimpendulo zamayeza)

Ngokuqhelekileyo, i-norepinephrine isetyenziswa kunye namanye amayeza kwezi meko.

Ukongeza, i-norepinephrine ikwanikwa njengonyango lwezifo ezinzima ezifana nezi:

• Ukudumba kweSeptic: Oku kungaba yingozi ebomini, kwaye yimeko apho uxinzelelo lwegazi luyehla ngendlela engaqhelekanga emva kosulelo.
• Umothuko we-neurogenic: Imeko enokuba yingozi ebomini ebangelwa kukwenzakala komqolo.
• I-Pericardial tamponade: Imeko apho ulwelo olugqithisileyo luqokelelana kwindawo ejikeleze intliziyo, nto leyo ebeka uxinzelelo entliziyweni.
• Uxinzelelo lwegazi oluphantsi kakhulu (i-Critical hypotension).

Zithini iziphumo ebezingalindelekanga ezinokubakho xa usebenzisa i-norepinephrine njengenaliti?

Xa kuthathwa njengenaliti ye-norepinephrine, kukho iziphumo ebezingalindelekanga ezininzi ezifuna ukhathalelo lwezonyango. Nazi:

• Iimpendulo ze-allergy: Ukurhawuzelelwa lusu, ukurhawuzelelwa, ukurhawuzelelwa, ukudumba kobuso, imilebe, okanye ulwimi.
• Ubunzima bokuphefumla, ukuphefumla kancinci.
• Ukubetha kwentliziyo okungaqhelekanga, ukubetha kwentliziyo okungapheliyo, okanye iintlungu zesifuba.
• Intlungu, ukubomvu, okanye ukudumba apho kufakwe khona inaliti.

Ukuba kwenzeka into efana nale, kufuneka uxelele ugqirha ngokukhawuleza.

Zeziphi iingxaki zempilo ezinokubakho ukuba amanqanaba e-norepinephrine ehla?

Ukuba inqanaba le-norepinephrine emzimbeni liyehla, ezi ngxaki zempilo zilandelayo zinokwenzeka:

• Ixhala.
• Uxinzelelo.
• Ingxaki yokungakwazi ukunikel’ ingqalelo (ADHD).
• Intloko ebuhlungu.
• Iingxaki zememori.
• Iingxaki zokulala.
• Uxinzelelo lwegazi oluphantsi (iHypotension).
• Iswekile ephantsi egazini (iHypoglycemia).
• Utshintsho kuxinzelelo lwegazi kunye nesantya sentliziyo.
• Ukunqongophala kwe-dopamine beta-hydroxylase. Esi sisifo esingaqhelekanga kakhulu esibangelwa yimfuza. Kule meko, umzimba wethu awukwazi ukwenza i-norepinephrine kwi-dopamine.

Ukuba unale mpawu, ayikokuba unezinga eliphantsi le-norepinephrine. Kodwa kungcono ukubona ugqirha ukuze akunike ingcebiso.

Kuthekani ukuba amanqanaba e-norepinephrine ayanda?

Ukuba amanqanaba e-norepinephrine ayanda emzimbeni, ezi meko zempilo zilandelayo zinokwenzeka:

• Uxinzelelo lwegazi oluphezulu (uxinzelelo lwegazi oluphezulu).
• Ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga.
• Ukubila okugqithisileyo.
• Ulusu olubandayo okanye olukhanyayo.
• Intloko ebuhlungu kakhulu.
• Ukungazinzi, ukuxhalaba.
• I-Pheochromocytoma: Le yithumba elikhula kwi-adrenal gland.

Kuthiwa abantu abanamanqanaba aphezulu e-norepinephrine basengozini enkulu yokuba nesifo sentliziyo, isifo semithambo yegazi, kunye nomonakalo wezintso.

Yintoni onokuyenza ukuze unyuse amanqanaba e-norepinephrine ngokwendalo?

Unokunyusa ngokwendalo amanqanaba akho e-norepinephrine ngokwenza izinto ezinje:

• Ukuzilolonga rhoqo: Zilolonge ubuncinane imizuzu engama-30 ngosuku, ubuncinane iintsuku ezintlanu ngeveki. Cinga ngokubaleka, ukuhamba ngeenyawo, okanye ukukhwela ibhayisekile.
• Lala ngokwaneleyo: Zama ukulala ubuncinane iiyure ezisixhenxe ukuya kwezisibhozo ngosuku. Ukulala kakuhle kufana neyeza lomzimba nengqondo.
• Yitya ukutya okunesondlo: Faka ukutya okuneproteni eninzi njengenyama, inkukhu, intlanzi, amantongomane (umz., iicashews, amantongomane), amaqanda kunye netshizi. Ezi ziqulathe i-amino acid tyrosine, enceda ekwenzeni i-norepinephrine.
• Ukumamela umculo, ukwenza into ekwenza wonwabe: Xa umamela ingoma oyithandayo okanye usenza into oyithandayo, uziva wonwabile. Kuthiwa xa wonwabile, ukukhululwa kwe-norepinephrine kuyanda.

Zithini izinto ezifanayo nezahlukileyo phakathi kwe-Epinephrine ne-Norepinephrine?

I-Norepinephrine yi-neurotransmitter kunye ne-hormone, kodwa ngokuyintloko isebenza njenge-neurotransmitter. I-Norepinephrine, eyaziwa ngokuba yi-noradrenaline, ibalulekile kwimpendulo yomzimba wakho "yokulwa okanye ukubaleka". Njengeyeza, i-norepinephrine isetyenziselwa ukonyusa nokugcina uxinzelelo lwegazi kwiimeko zempilo ezilinganiselweyo, zexesha elifutshane, neziqatha.

I-Epinephrine, eyaziwa ngokuba yi-adrenaline, yi-hormone kunye ne-neurotransmitter. Zombini ziveliswa yi-adrenal glands, kwaye zombini zisabela kuxinzelelo. Nangona kunjalo, i-epinephrine isebenza ngokuyintloko njenge-hormone , ichaphazela intliziyo ngaphezu kwe-norepinephrine,Ichaphazela imetabolism. I-Norepinephrine isebenza kakhulu ekuthinteleni imithambo yegazi nasekugcineni uxinzelelo lwegazi.

Ngamafutshane, aba babini bafana nabazalwana ababini abasebenza kunye, kodwa imisebenzi yabo ephambili yahlukile kancinci.

Okokugqibela, izinto ekufuneka uzikhumbule

Ngoko ke, mhlawumbi ngoku uyaqonda ukuba i-norepinephrine yikhemikhali encinci kodwa enamandla kakhulu emizimbeni yethu. Idlala indima enkulu kuyo yonke into ukususela ekusigcineni silumkile kwimpendulo "yokulwa okanye ukubaleka" esinceda sisinde xa kukho ingozi.

Nokuba izinga liphantsi kakhulu okanye liphezulu kakhulu, iingxaki zempilo zinokubakho. Kungoko ke, kubalulekile ukuzama ukugcina oku kusemgangathweni. Singakunceda ngezinto ezilula ezifana nokulala kakuhle, ukuzilolonga, ukonwaba, kunye nokutya okunesondlo.

Ukuba unemibuzo okanye amathandabuzo malunga noku, eyona nto ingcono onokuyenza kukubona ugqirha. Banokukunika icebiso elifanelekileyo.

Ngoko ke, ukuqaphela ezi zinto zimangalisayo ezenzekayo emizimbeni yethu kubaluleke kakhulu kubomi obusempilweni!

I- Norepinephrine, i-noradrenaline, i-neurotransmitter, i-hormone, ukulwa okanye ukubaleka, uxinzelelo, uxinzelelo lwegazi