Ngaba ugqirha wakho ukuxelele okanye umntu osapho lwakho ukuba niqale ukuthatha iyeza elibizwa ngokuba yiPacritinib? Kuqhelekile ukuba nemibuzo kunye neenkxalabo xa usiva ngeyeza elikhethekileyo. Ngoko ke, namhlanje siza kuthetha ngayo yonke into ngendlela elula neyobuhlobo, njengokuthi liyintoni eli yeza, indlela yokulisebenzisa, kunye noko kufuneka ukuqaphele.
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Lithini eli yeza libizwa ngokuba yiPacritinib?
Ngamafutshane, iPacritinib liyeza elisetyenziselwa ukunyanga imeko ebizwa ngokuba yi -myelofibrosis . I-Myelofibrosis ngumhlaza owenzeka kumongo wethu wamathambo. Kule meko, izicubu ezinee-fibrous zithatha indawo yeeseli eziphilileyo kumongo wamathambo, ziphazamisane nokuveliswa kwegazi.
I-Pacritinib ikwiqela lamayeza abizwa ngokuba yi-kinase inhibitors . Khawuthelekelele ukuba ngaphakathi kwiiseli zomzimba wethu, kukho ii-messenger ezincinci (iiproteni) ezinika imiqondiso kwiiseli ukuba zikhule kwaye zahlukane. Okwenziwa leli yeza kukuyeka umsebenzi weeproteni ezithile ezinceda ezo seli zigulayo zikhule. Kufana nokucima iswitshi engalunganga kumatshini osebenzayo. Ngale ndlela, ukulawula ukukhula kweeseli ezigulayo ngumsebenzi ophambili wale yeza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale amayeza
Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukuba ugqirha wakho abe nomfanekiso opheleleyo wemeko yakho yempilo. Kuba olo lwazi luya kuqinisekisa ukuba eli yeza likulungele na, kwaye lifanele linikwe njani. Ukuba unayo nayiphi na kwezi zilandelayo, qiniseka ukuba uxelele ugqirha wakho.
| Isimo/umkhwa | Inkcazo |
|---|---|
| Ukopha kunye nokuqhekeka kwegazi | Ukuba ukhe waba nengxaki yokopha okanye ingxaki yokujiya kwegazi ngaphambili. |
| Isifo sentliziyo | Ukuba ukhe wahlaselwa yintliziyo, isifo sohlangothi, okanye esinye isifo sentliziyo ngaphambili. |
| Ezinye iimeko zonyango | Iimeko ezifana neminye imihlaza, isifo sesibindi okanye sezintso, usulelo olukhoyo, urhudo, okanye ukuhlanza. |
| Indlela yokuphila | Ukuba utshaya icuba okanye icuba. |
| Izicwangciso zexesha elizayo | Ukuba uza kutyandwa kwixesha elizayo. |
| Inkcukacha zimntu | Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa. |
| Ii-aleji | Ukuba une-allergy kwi-pacritinib okanye naliphi na elinye iyeza, ukutya, okanye idayi. |
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Check Availability →Indlela yokusebenzisa amayeza ngokuchanekileyo?
Kubaluleke kakhulu ukusela amayeza akho kanye njengoko ugqirha wakho ekuyalele, ngexesha elifanelekileyo.
- Eli yeza liza likwimo yekhaphu .
- Ginya ikhaphu yonke ngamanzi . Ungaze uyihlafune, uyiqhekeze, okanye uyityumze.
- Ziqhelise ukusela amayeza akho ngexesha elifanayo yonke imihla. Ngale ndlela, awuyi kuyilibala.
- Eli yeza lingasetyenziswa ngaphambi okanye emva kokutya.
- Qhubeka usela amayeza de ugqirha wakho akuxelele ukuba uyeke.
Isilumkiso: Eli yeza limiselwe wena wedwa. Musa ukwabelana ngalo nabanye abantu nangasiphi na isizathu.
Yintoni omawuyenze ukuba uphoswe yidosi yeyeza?
Ungakhathazeki. Ukuba uphoswe yidosi, yiyeke ngokupheleleyo. Thatha idosi yakho elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye ukuze ubuyisele idosi ongayithathanga.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Ukuba ucinga ukuba uthathe ngaphezu kwedosi emiselweyo, qhagamshelana neZiko loLwazi lweePoisons kwiSibhedlele sikaZwelonke saseColombo ngoko nangoko.Tsalela umnxeba okanye uye kwiSebe lezeMpilo eziNgxamisekileyo (ETU) elikufutshane nawe.
Amanye amayeza anokusebenza kunye nale mayeza
Kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini, amayeza emifuno, kunye nezongezo), njengoko amanye amayeza anokusebenzisana ne-pacritinib, atshintshe iziphumo zayo okanye andise iziphumo zayo ezingalindelekanga.
Ngokukodwa, kucetyiswa kakhulu ukuba ungayithathi i-pacritinib kunye namayeza alandelayo.
- Amanye amayeza okulwa neentsholongwane ze-HIV okanye i-AIDS
- Amanye amayeza okubulala iintsholongwane, anjenge-clarithromycin kunye ne-erythromycin
- Amayeza osulelo lwefungus, njenge ketoconazole kunye ne itraconazole
- Amayeza okulwa nesifo sokuwa afana ne-carbamazepine kunye ne-phenytoin
- I-Rifampin
- Imveliso yemifuno ye-St. John's wort
Ukongeza, isenokudibana namanye amayeza anokubangela utshintsho kwisingqisho sentliziyo (ukwandisa ixesha le-QT). Olu luhlu aluphelelanga. Ngoko ke qiniseka ukuba uxelela ugqirha wakho ngawo onke amayeza owasebenzisayo.
Izinto ekufuneka uzilumkele xa usebenzisa amayeza
- Ukuhlolwa rhoqo: Ugqirha wakho uza kukucela ukuba uze ekliniki rhoqo ukuze ajonge imeko yakho. Uza kuyalela novavanyo lwegazi (umsebenzi wegazi). Musa ukuphoswa zezi zinto kwaye uzenze rhoqo.
- Umngcipheko wokopha: Eli yeza linokuyonyusa kancinci ingozi yokopha okanye ukukrweleka lula. Xelela ugqirha wakho ngoko nangoko ukuba ubona ukopha okungaqhelekanga (umz., kwiintsini zakho, empumlweni) okanye ukukrweleka okukhulu.
- Umngcipheko wokosuleleka: Eli yeza lisenokunciphisa kancinci ukusebenza kwenkqubo yakho yokuzikhusela komzimba. Ke ngoko, umngcipheko wokufumana usulelo uphezulu. Ukuba ufumana iimpawu ezinje ngomkhuhlane, ukubanda, umphimbo obuhlungu, kunye nokukhwehlela, musa ukuzinyanga kwaye utsalele umnxeba ugqirha wakho. Zama ukuhlala kude neendawo apho kukho abantu abagulayo.
- Umngcipheko womhlaza: Kukho ubungqina bokuba eli yeza linokunyusa kancinci umngcipheko wezinye iintlobo zomhlaza. Thetha nogqirha wakho ngale nto ukuze ufumane ulwazi oluthe kratya.
- Iziphumo ekuzaleni: Eli yeza lisenokuchaphazela ukuzala kwamadoda. Ukuba unethemba lokuba nabantwana, thetha nogqirha wakho ngale nto ngaphambi kokuba uqale unyango.
- Ukuncancisa: Musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye kangangeeveki ezimbini emva kokuba uyekile ukusebenzisa eli yeza.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengalo naliphi na iyeza, eli yeza linokubangela iziphumo ebezingalindelekanga kwabanye abantu. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Nazi ezinye zeziphumo ebezingalindelekanga ezinokubakho.
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
|---|---|
| Iimpendulo ze-Allergic | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ukopha | Indle emnyama okanye enegazi, ukuhlanza into efana nekofu egayiweyo, amabala abomvu eluswini, ukopha okungaqhelekanga emehlweni/ezintsinini/empumlweni. |
| Ihlwili legazi | Intlungu esifubeni, ukuphefumla kancinci, intlungu emilenzeni, ukudumba, okanye ukufudumala. |
| Iimpawu zoHlaselo lweNtliziyo | Ubunzima bokuphefumla, iintlungu okanye ukuqina esifubeni/entanyeni/ezingalweni, ukudinwa kakhulu. |
| Utshintsho kwisantya sentliziyo | Ukudinwa, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga, ukuziva utyhafile. |
| Iimpawu zestroke | Ukutshintsha kombono, ukudideka, ubunzima bokuthetha okanye ukuqonda, ukuba ndindisholo ngequbuliso, ubunzima bokuhamba. |
| Okunye | Urhudo oluqatha okanye ukuhlanza, iimpawu zosulelo (umkhuhlane, ukubanda). |
| Izinto ezingaqhelekanga ukuba zimbi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Ukudumba | Ukudumba kwamaqatha, iinyawo, okanye izandla. |
Umyalezo Wokuya Ekhaya
- I-Pacritinib liyeza elifanele lisetyenziswe ngononophelo olukhulu, kuphela phantsi kwengcebiso kagqirha.
- Ngaphambi kokuba uqale amayeza, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye nawo onke amanye amayeza owasebenzisayo.
- Ukuba ufumana ukopha okungaqhelekanga, iimpawu zosulelo, okanye ezinye iziphumo ebezingalindelekanga ezibi ngelixa usebenzisa amayeza, funa ingcebiso kagqirha ngokukhawuleza.
- Musa ukwabelana ngamayeza owanikwe ngugqirha nabanye abantu nangasiphi na isizathu.
- Ukuba ufuna ukuncancisa umntwana okanye uceba ukukhulelwa, thetha nogqirha wakho ngaphambi kokuba uqale unyango.
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