Isisombululo esitsha kwi-measles? Masifunde ngesitofu sokugonya sePegloticase!

Abantu abaninzi bayazazi ezi zifo zibizwa ngokuba yi "Gout", akunjalo? Khawucinge nje, xa uvuka kusasa, ilungu lakho elikhulu leenyawo livakala ngathi liyatsha, lidumbile, kwaye libomvu. Awukwazi nokuma. Akulula ukuphila nale ntlungu inganyamezelekiyo kunye nemeko yamalungu edumbileyo. Ngoko ke, namhlanje siza kuthetha ngonyango olukhethekileyo lwe -gout engapheliyo , oko kukuthi, i-gout ebikho ixesha elide kwaye ngamanye amaxesha kunzima ukuyilawula ngamayeza aqhelekileyo. Leyo yi-gonyo ye-Pegloticase.

Luhlobo luni lonyango iPegloticase?

Ngamafutshane, iPegloticase yienzyme . Ngoku usenokuba uzibuza ukuba yintoni ienzyme. Ienzyme yiproteni ekhethekileyo enceda iinkqubo ezithile zeekhemikhali emzimbeni wethu, ezifana nokugaya ukutya, ukuba ziqhubeke kakuhle. Ngoko ke le enzyme ebizwa ngokuba yiPegloticase isetyenziswa, njengoko bekutshiwo ngaphambili, ukunyanga i-gout engapheliyo, ebikho ixesha elide kwaye ngamanye amaxesha kunzima ukuyilawula ngamanye amayeza. I-Gout yenzeka xa ikhemikhali ebizwa ngokuba yi-uric acid isanda emzimbeni. Eli yeza lisebenza ngokunciphisa amanqanaba e-uric acid.

Ugqirha wakho angakunika eli yeza phantsi kwegama lophawu elithi ``Krystexxa.'' Elo ligama eliqhelekileyo leli yeza.

Nangona eli liyeza elithile le-gout, oogqirha ngamanye amaxesha banokulisebenzisa kwezinye iimeko zonyango. Ke ngoko, ukuba unemibuzo okanye iinkxalabo malunga neli yeza, kungcono ukubuza ugqirha wakho okanye ikhemisti ngaphandle kokuzibamba. Baza kukuchazela ngqo.

Zeziphi izinto ekufuneka ndizixelele ugqirha ngaphambi kokuba ndiqalise eli yeza?

Ngaphambi kokuba uqale unyango ngePegloticase, kubaluleke kakhulu ukuba unike ugqirha wakho ingxelo epheleleyo nenyanisekileyo ngempilo yakho. Oku kwenzelwa ukuba ugqirha wakho akwazi ukugqiba ukuba olu nyango lukulungele na okanye ukuba ufuna naluphi na unyango olukhethekileyo. Ngokuqinisekileyo baya kufuna ukwazi ukuba unayo nayiphi na kwezi meko zilandelayo:

• Ukunqongophala kwe-G6PD: Oku kusenokuvakala njengegama lezonyango, kodwa ngokulula, kukunqongophala kwe-enzyme ethile kwiiseli zethu ezibomvu zegazi. Ukunika abantu abanesifo i-pegloticase kunokuba yingozi. Ngoko ke, ukuba unayo le nto, ngokuqinisekileyo kufuneka ubaxelele.
• Ukuba unesifo sentliziyo: Ukuba unesifo sentliziyo, umzekelo, isifo sentliziyo sangaphambili, okanye ukuba unengxaki yokusebenza kwentliziyo, sixelele ngaso.
• Iingxaki zokunganyamezelani komzimba:Qiniseka ukuba uxelela ugqirha wakho ukuba wakha waba ne-allergy okanye naluphi na ukusabela okungaqhelekanga kwiPegloticase, naluphi na olunye unyango, ukutya (umz., abanye abantu bane-allergy kwizinto ezifana neepinati), iidayi, okanye izithinteli.
• Ukukhulelwa: Ukuba ukhulelwe okanye uceba ukukhulelwa kungekudala, kubaluleke kakhulu ukuxelela ugqirha wakho, njengoko amanye amayeza anokuchaphazela umntwana ngexesha lokukhulelwa.
• Ukuncancisa: Ukuba ungumama oncancisayo, kufuneka ukukhankanye oko, kuba amanye amayeza anokudluliselwa kumntwana ngobisi lwebele.

Ukuba uzithetha ngokuchanekileyo ezi zinto, ugqirha angakunyanga ngokukhuselekileyo.

Unikwa njani eli yeza lePegloticase?

Eli yeza alilophilisi olithathayo okanye inaliti onokuyithatha ekhaya. Linikwa njenge-infusion emthanjeni . Kufana nokukunika ibhotile ye-saline, kwaye iyeza lifakwa kancinci emzimbeni wakho. Oku kudla ngokwenziwa yingcali yezempilo eqeqeshiweyo, njengogqirha okanye umongikazi, esibhedlele okanye kwikliniki ekhethekileyo . Oku kuthetha ukuba awuyi kukwazi ukulithatha uliyise ekhaya.

Ngaphambi kweseshoni nganye yonyango, uza kunikwa incwadana yolwazi ekhethekileyo (iMedGuide) echaza yonke into malunga nale yeza, indlela elisebenza ngayo, kunye nemiphumo enokubakho. Kubaluleke kakhulu ukulifunda ngononophelo kwaye ungalicingi nje njengephepha. Liqulethe ulwazi oluninzi olubalulekileyo kukhuseleko lwakho.

Ngaba eli yeza linokunikwa abantwana abancinci?

Eli yeza lidla ngokunikezelwa kubantu abadala. Ukuba unika abantwana abancinci eli yeza, kufuneka uthethe nogqirha wabantwana ngalo kwaye unyamekele ngokukodwa phantsi kweliso lakhe kunye neengcebiso zakhe. Ayizizo zonke amayeza afanelekileyo kubantwana abancinci.

Kuthekani ukuba ngempazamo usele amayeza amaninzi kakhulu? (Umthamo ogqithisileyo)

Ekubeni oku kunikwa esibhedlele, phantsi kweliso leengcali zempilo, akukho mfuneko yokukhathazeka ngokunikwa amayeza amaninzi kakhulu. Nangona kunjalo, ukuba ucinga ukuba kukho into eyenzekileyo kuwe nangayiphi na indlela, okanye ukuba uziva ungakhululekanga ngendlela engaqhelekanga, xelela ugqirha okanye umongikazi okhoyo ngelo xesha ngoko nangoko. Baza kuthatha amanyathelo afunekayo.

Okubaluleke kakhulu: Eli yeza lelakho kuphela. Musa ukulinika omnye umntu oneempawu zakho, okanye uthethe ngalo, ucinga ukuba liza kusebenza kuye. Imeko yomntu wonke yahlukile.

Wenza ntoni ukuba awukwazi ukuthatha amayeza akho ngexesha?

Kubaluleke kakhulu ukusela amayeza ngosuku olufanelekileyo nangexesha elifanelekileyo kolu nyango. Le yindlela onokufumana ngayo iziphumo ezilungileyo. Ukuba awukwazi ukuya kwi-aphoyintimenti yakho, nokuba ngomhla oxelelwe ukuba uze kuthatha amayeza,Fowunela ugqirha wakho okanye ikliniki ngokukhawuleza kwaye ubazise. Baza kukutshintsha ixesha lakho okanye bakunike iingcebiso ngento omawuyenze. Musa ukuhlala nje.

Ziziphi ezinye izinto ezinokusebenzisana nale mithi?

Kukho amayeza athile anokusebenzisana nePegloticase. Oku kuthetha ukuba ukusebenza kakuhle kwale mayeza kunokuncipha, okanye iziphumo ebezingalindelekanga zinokwanda, okanye kuvele iingxaki ezintsha. Amanye amayeza, ingakumbi lawo asetyenziselwa i-gout, akufuneki asetyenziswe nePegloticase. Umzekelo:

• `I-Allopurinol`
• `Febuxostat`
• `Iprobenecid`
• 'I-Sulfinpyrazone'

Olu luhlu lungasentla lusenokungabandakanyi zonke iindlela ezinokwenzeka zokusebenzisa amayeza. Ngoko ke, xelela ugqirha wakho ngawo onke amayeza owasebenzisayo – amayeza kagqirha, amayeza angagunyaziswanga ngugqirha, amayeza esintu, iivithamini, kunye nezongezo zokutya. Kwakhona, qiniseka ukuba uxelela ugqirha wakho ukuba uyatshaya, usela utywala, okanye usebenzisa ezinye iziyobisi ezingekho mthethweni. Ezi zinokuchaphazela indlela amayeza akho asebenza ngayo.

Yintoni esifanele siyilumkele ngakumbi xa sithatha eli yeza?

Kukho izinto ezininzi ekufuneka wena kunye neqela lezonyango elininyangayo niziqaphele kakhulu xa nisebenzisa eli yeza.

• Iimpendulo Ezinzima Zokwaliwa Yi-allergy: Le yeyona iphambili. Eli yeza ngamanye amaxesha linokubangela iimpendulo ezinzima kakhulu zokukwaliwa yi-allergy (ezifana ne-anaphylaxis) . Oku kudla ngokukwenzeka ngexesha lokufakwa kwenaliti. Ukunciphisa le ngozi, ugqirha wakho angakuxelela ukuba uthathe amanye amayeza (afana ne-antihistamines okanye i-corticosteroids) ngaphambi kokuba ufumane inaliti ye-Pegloticase. Oku kubizwa ngokuba yi-"pre-medication." Kubaluleke kakhulu ukuthatha amayeza kanye njengoko ugqirha wakho ekuxelela, nangexesha elifanelekileyo.
• Ukubeka iliso kwimpilo: Ngelixa usela eli yeza kwaye okwethutyana emva koko, iingcali zezempilo ziya kubeka iliso kwimeko yakho (umz. izinga lentliziyo, uxinzelelo lwegazi, ukuphefumla) ngokusondeleyo. Ngoko ke akukho nto ibalulekileyo. Baza kukwazi ukubona ngokukhawuleza naluphi na utshintsho oluncinci.
• Nika ingqalelo kwiimpawu: Nika ingqalelo ekubeni iimpawu zakho ze-goiter (umz., iintlungu zamalungu, ukudumba) ziya zisiba ngcono kancinci kancinci okanye zibonakala zisiba mandundu. Ukuba kukho naluphi na utshintsho olunjalo, xelela ugqirha wakho okanye ingcali yezempilo ngokukhawuleza.
• Uvavanyo lwegazi:Kuya kufuneka uphinde uhlolwe rhoqo, njengovavanyo lwegazi olulula , ukujonga amanqanaba e-uric acid yakho, ukuba amayeza akho ayasebenza na, kwaye ukuba kukho naziphi na ezinye iingxaki. Kubalulekile ukwenza oku rhoqo.

Zithini iziphumo ebezingalindelekanga zale mithi yePegloticase?

Njengalo naliphi na iyeza, iPegloticase inokubangela ezinye iziphumo ebezingalindelekanga. Nangona kunjalo, oku akuthethi ukuba wonke umntu othatha eli yeza uza kuzifumana. Abanye abantu basenokuphila kakuhle ngaphandle kweziphumo ebezingalindelekanga. Nangona kunjalo, kubalulekile ukuqaphela iziphumo ebezingalindelekanga ezinokubakho. Ezinye iziphumo ebezingalindelekanga zinzima, kwaye ukuba ubona naziphi na kuzo, kufuneka uxelele ugqirha wakho ngoko nangoko.

Iziphumo ebezingalindelekanga ekufuneka uzixele kugqirha wakho ngoko nangoko:

Ukuba ufumana nayiphi na kwezi, kufuneka ufune ingcebiso kagqirha ngoko nangoko.

• Ii-Allergy: Ukurhawuzelela kwesikhumba, ukurhawuzelela okufana ne-eczema okanye ii-hives, ukudumba kobuso, imilebe, ulwimi okanye umqala (oku kunokwenza kube nzima ukuphefumla).
• Ukuvakalelwa ngathi ulusu lwakho luba luhlaza okwesibhakabhaka: Ukuba iindawo ezifana nemilebe yakho kunye neenzipho zakho ziba luhlaza okwesibhakabhaka, oko kungaba luphawu lokunqongophala komoya-mpilo.
• Ubunzima bokuphefumla: Ukuba unengxaki yokuphefumla, kusenokufana nokuphefumla.
• Intlungu yesifuba okanye ukuziva uxinezelekile esifubeni: Oku kungaba luphawu lokuhlaselwa yintliziyo.
• Ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga.
• Ukuziva utyhafile okanye unentloko ebuhlungu, uyawa.
• Intlungu xa uchama: Oku kungaba luphawu losulelo.
• Ukudumba kwamaqatha, iinyawo, nezandla.
• Ukwanda ngequbuliso kweempawu ze-gout: Oku kunokwenzeka ngamanye amaxesha xa uqala ukuthatha amayeza, kodwa xelela ugqirha wakho .
• Ukopha okanye ukukrwela okungaqhelekanga: Ukuba ufumana imikrwelo emzimbeni wakho wonke.
• Ukuziva ubuthathaka okanye udiniwe ngendlela engaqhelekanga.

Iziphumo ebezingalindelekanga ezihlala zingadingi nyango olukhawulezileyo (kodwa ukuba ziyaqhubeka okanye ziyakukhathaza, kufuneka uxelele ugqirha wakho ):

Nokuba ezi zinto azibalulekanga kangako, xelela ugqirha wakho ukuba ziyakukhathaza.

• Intlungu yemisipha.
• Isicaphucaphu, ukuhlanza.
• Ndiziva ngathi ndikhathazekile yisisu, ndiziva ndihluthi (Isisu esibuhlungu).

Khumbula, olu luhlu lusenokungabandakanyi zonke iziphumo ebezingalindelekanga. Ukuba ubona nantoni na engaqhelekanga okanye eyahlukileyo emzimbeni wakho, ungathandabuzi ukucela ingcebiso kugqirha wakho.

Uligcina phi eli yeza? Ndingalithatha ndiliyise ekhaya?

Hayi, eli yeza libizwa ngokuba yiPegloticase alikho into onokuyithenga ekhemesti uze uye nayo ekhaya.Ifumaneka kuphela esibhedlele okanye kwikliniki evunyiweyo, apho unikwa khona yingcali yezempilo eqeqeshiweyo. Ngoko ke akufuneki ukhathazeke ngendlela yokugcina okanye yokukhusela amayeza.

Eyona nto ibalulekileyo ekufuneka uyikhumbule (Umyalezo Wokuya Ekhaya)

Kulungile, masiphinde sikukhumbuze ngezona zinto zibalulekileyo ekufuneka uzikhumbule kwizinto esithethe ngazo.

• I-Pegloticase yinaliti ekhethekileyo enikwa i-gout engapheliyo.
• Oku kunikwa njengenaliti emthanjeni esibhedlele okanye ekliniki, phantsi kweliso elibukhali likagqirha .
• Ngaphambi kokuba uqale unyango, kubalulekile ukuba uxelele ugqirha wakho ngalo lonke ulwazi lwakho lwempilo kunye nawo onke amanye amayeza owasebenzisayo .
• Lumka kakhulu malunga neziphumo ebezingalindelekanga, ingakumbi ii-allergies, ngexesha nasemva kokusela amayeza.
• Kubaluleke kakhulu ukufumana unyango ngexesha elifanelekileyo nokulandela imiyalelo kagqirha.

Okokugqibela, ukuba unemibuzo, amathandabuzo, okanye iinkxalabo malunga neli yeza lePegloticase okanye imeko yakho, nceda uzive ukhululekile ukubuza ugqirha wakho, ikhemisti, okanye umboneleli wezempilo. Ukuba nolwazi olufanelekileyo yeyona ndlela ilungileyo yokuhlala usempilweni.

Siyathemba ukuba eli phepha lolwazi likuncede waqonda eli yeza. Kodwa khumbula, eli asilo nkcazo ipheleleyo, sisishwankathelo nje. Lisenokungabandakanyi yonke into. Ngoko ke kubalulekile ukuthetha nogqirha wakho rhoqo.

I- Pegloticase, iGout, iGout engapheliyo, i-Enzyme, Iziphumo ebezingalindelekanga, Amayeza, Unyango