Ubungacinga ntoni ukuba ugqirha uxelele umntu olwa nomhlaza athi, "Masenze unyango olukhethekileyo lwelaser ngoku?" Le ayisiyolaser eqhelekileyo. Okwenzayo kukunika umzimba iyeza elikhethekileyo elinamathela kwiiseli zomhlaza lize lizitshabalalise xa ukukhanya kwelaser kuzibetha. Elinye iyeza elikhethekileyo libizwa ngokuba yiPorfimer. Masithethe ngale nto ngendlela elula necacileyo namhlanje.
Yintoni le Porfimer?
Ngamafutshane, i-porfimer sisiyobisi esibangela ukukhanya. Indlela esebenza ngayo iyamangalisa. Cinga ngayo njengemagnethi enamathela kuphela kwiiseli zomhlaza.
Sifaka eli yeza emzimbeni ngemithambo yegazi. Emva koko amasuntswana eli yeza ahamba emzimbeni wonke, ngakumbi afumane aze anamathele kwiiseli zomhlaza. Alichaphazeli kangako iiseli eziphilileyo.
Emva kweentsuku ezimbini emva kokuba eli yeza linikwe, ugqirha uyalela ukukhanya okukhethekileyo kwelaser kwindawo yomhlaza. Amasuntswana eli yeza anamathele kwiiseli zomhlaza afunxa ukukhanya kwelaser aze asebenze. Ukusabela kweekhemikhali okubangelwayo kutshabalalisa kuphela iiseli zomhlaza ezinamathele kuzo. Sibiza le nkqubo yonke ngokuba yi-photodynamic therapy (PDT) .
Le ndlela yonyango isetyenziswa kakhulu kwezi zinto zilandelayo:
- Umhlaza womqala
- Yomhlaza wemiphunga
- Nyanga imeko engaphambi kokuba nomhlaza ebizwa ngokuba yiBarrett's esophagus .
Ngaphandle koku, eli yeza lingasetyenziselwa nezinye iimeko zonyango ngokwengcebiso kagqirha.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi konyango
Ngaphambi kokuba uqale olu nyango, kubaluleke kakhulu ukunika ugqirha wakho inkcazo epheleleyo yemeko yakho yempilo. Qiniseka ukuba uyamxelela ukuba unayo nayiphi na kwezi meko zilandelayo:
- Ukuba unezilonda zomqala, i-fistula, okanye imithambo erhabaxa.
- Ukuba unesifo sezintso okanye isifo sesibindi.
- Ukuba unesifo esingaqhelekanga esibizwa ngokuba yi-porphyria.
- Ukuba usandul’ ukufumana okanye okwangoku ufumana unyango lwemitha.
- Ukuba oogqirha bakho bakuxelele ukuba umhlaza wakho usasazeke (usususwe) waya kwimithambo yegazi emikhulu.
- Ukuba une-allergy kwiPorfimer okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba ukhulelwe , uzama ukukhulelwa , okanye uncancisa .
Ulisebenzisa njani eli yeza?
Eli asiloyeza onokulithatha uye nalo ekhaya. Eli yeza linikwa ngokujova emthanjeni esibhedlele okanye ekliniki ngugqirha okanye umongikazi oqeqeshwe ngokukodwa koku.
Ukuba unika abantwana eli yeza, kufuneka ukhathalelo olukhethekileyo. Thetha nogqirha wezingane ngale nto.
Kuthekani ukuba umthamo weyeza uyanda?
Oku akunakwenzeka ukuba kwenzeke kuba kunikwa esibhedlele. Nangona kunjalo, ukuba ucinga ukuba uthathe amayeza amaninzi kakhulu, qhagamshelana neZiko loLwazi lweeTyhefu zeSizwe kwiSibhedlele seSizwe saseColombo ngoko nangoko, okanye uye kwiYunithi yoNyango oluNgxamisekileyo (ETU) ekufutshane.
Kuthekani ukuba ndiphoswa yidosi?
Kubaluleke kakhulu ukufumana unyango ngomhla nexesha ugqirha akunike lona. Ukuba ngesizathu esithile awukwazi ukuya ngelo xesha, fowunela ugqirha wakho ngoko nangoko umxelele.
Ngaba kukho unxibelelwano phakathi kwezinye amayeza?
Ewe, amanye amayeza anokusebenzisana nalo mayeza. Ngoko ke xelela ugqirha wakho ngawo onke amayeza owasebenzisayo (amayeza ezinye izifo, iivithamini, amayeza esintu, izongezo zokutya). Kwakhona, xelela ugqirha wakho ukuba utshaya okanye usela utywala.
Iingxaki zinokwenzeka, ngakumbi, ngeentlobo ezilandelayo zamayeza:
- Ezinye iintlobo zee-antibiotics - umzekelo, ii-fluoroquinolones, ii-sulfonamides, kunye nee-tetracyclines.
- Amanye amayeza esifo seswekile.
- I-Griseofulvin liyeza lokulwa nokubola.
- Iiphenothiazines ziziyobisi ezisetyenziselwa ukugula ngengqondo.
- I-Thiazide diuretics ngamayeza okunyusa ukukhupha umchamo.
Olu luhlu aluphelelanga, ngoko ke kungcono ukuxelela ugqirha wakho yonke into oyithathayo.
Izinto ekufuneka ziqwalaselwe ngexesha lonyango
Ufanele uzinyamekele kakuhle emva kokusebenzisa eli yeza.
Ukukhuselwa elangeni nasekukhanyeni okuqaqambileyo
Eli lelona cebiso libalulekileyo nelifanele ukulandelwa . Emva kokusebenzisa eli yeza, ulusu lwakho luya kuba novelwano kakhulu ekukhanyeni. Ngoko ke, kuphephe ukukhanya kwelanga ngqo ubuncinane iintsuku ezingama-30 emva kokusebenzisa eli yeza . Ukuba kufuneka uphume, nxiba impahla egubungela umzimba wakho wonke kwaye unxibe umnqwazi. I-sunscreen ayiboneleli ngokhuseleko kule meko . Kwakhona, ngokuqinisekileyo kufuneka uziphephe izibane ezikhanyayo zangaphakathi kunye neebhedi zokutshisa ilanga.
Amehlo akho aya kuba novelwano kakhulu ekukhanyeni, ngoko ke nxiba iiglasi zelanga ezimnyama ezintle xa uphuma ngaphandle ubuncinane inyanga emva kokuba uthathe iyeza.
Ukukhulelwa kunye nokuncancisa
- Abafazi:Kuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye kangangeenyanga ezi-5 emva kokuyeka unyango.
- Amadoda: Ukuba ufumana olu nyango, kuphephe ukuba nguyise womntwana ngexesha lonyango kwaye emva kweenyanga ezi-5 emva kokuba uluyekile.
- Kuphephe ukuncancisa umntwana wakho ngeli xesha.
Eli yeza linokubangela ingozi enkulu kusana olungekazalwa.
Zithini iziphumo ebezingalindelekanga ezinokubakho?
Njengalo naliphi na iyeza, eli linokuba nemiphumo emibi. Eminye yayo inzima, eminye ixhaphakile.
| Imiphumela | Inkcazo |
|---|---|
| Iziphumo ebezingalindelekanga ezinzulu ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela, ukudumba kobuso, imilebe okanye ulwimi. |
| Ubunzima bokuphefumla | Ubunzima bokuphefumla, ukuphefumla kancinci. |
| Iintlungu zesifuba | Intlungu yesifuba eqatha ngequbuliso. |
| Ukukhohlela igazi | Ukukhohlela igazi nge-mucus. |
| Ifiva | Umkhuhlane ngaphandle kwesizathu. |
| Iimpawu zokulahleka kwegazi ( i-anemia ) | Ukuziva udiniwe ngaphezu kwesiqhelo, uzive utyhafile, kwaye uzive ungaphili. |
| Ubunzima bokuginya | Ubunzima bokuginya ukutya okanye isiselo. |
| Ngokwesiqhelo ayisiyongxaki inzulu (kodwa xelela ugqirha wakho ukuba iyaqhubeka) | |
| Iingxaki zenkqubo yokugaya ukutya | Ukuqhinwa, urhudo, isicaphucaphu, ukuhlanza. |
| I-Anorexia | Ukuncipha komnqweno wokutya. |
Ukuba ufumana naziphi na ezinye iimpawu ezingaqhelekanga ezingakhankanywanga kolu luhlu, thetha nogqirha wakho ngazo.
Umyalezo Wokuya Ekhaya
- I-Porfimer sisiyobisi esikhethekileyo esihlasela kwaye sitshabalalise iiseli zomhlaza sisebenzisa ukukhanya kwelaser.
- Emva kolu nyango, ulusu lwakho namehlo akho aya kuba buthathaka kakhulu ekukhanyeni ubuncinane iintsuku ezingama-30 . Zikhusele elangeni nasekukhanyeni okuqaqambileyo ngokupheleleyo. I-sunscreen ayiboneleli ngokhuseleko .
- Kubalulekile ukunika ugqirha wakho inkcazo epheleleyo yazo zonke ezinye iziyobisi, iivithamini, kunye neemeko zempilo ozisebenzisayo.
- Kuphephe ukukhulelwa okanye ukuba nguyise wabantwana ngexesha lonyango kwaye kangangeenyanga ezi-5 emva kokuba luphelile.
- Ukuba ufumana naziphi na iziphumo ebezingalindelekanga ezinje ngobunzima bokuphefumla, iintlungu zesifuba, okanye iimpembelelo ezimbi ze-allergy, xelela ugqirha wakho okanye isibhedlele ngokukhawuleza.
👩🏽⚕️ Imibuzo eyongezelelweyo (Ii-FAQ)
💬 Isetyenziselwa ntoni iPorfimer Injection/Photofrin?
Olu lunyango lomhlaza oluphucukileyo kakhulu (i-Photodynamic Therapy / PDT) kwezonyango! Olu gonyo lusetyenziswa kakhulu ukutshabalalisa amathumba anzima omhlaza emqaleni/endlebeni (umhlaza womqala) nasemiphungeni (i-NSCLC), ngaphandle kokuzisika nokuzisusa ngotyando, ngokusebenzisa 'ukukhanya kwelaser' ukutshabalalisa umhlaza.
💬 Eli yeza (iPorfimer) kunye nokukhanya kwelaser zitshabalalisa njani iiseli zomhlaza?
Eli yeza alinamsebenzi kuwe, lisebenza kuphela 'ekukhanyeni'! (Photosensitizer). Xa lifakwa emthanjeni, eli yeza lingena egazini lize lifakwe ngaphakathi kweeseli zomhlaza kangangeentsuku ezimbalwa. Emva koko ugqirha ufaka ityhubhu aze akhanyise 'ukukhanya okubomvu kwelaser (630nm Light)' kumhlaza! Kwakuba nje ukukhanya kufikile, eli yeza liyasabela ngaphakathi komhlaza lize lenze 'ioksijini enobuthi (ioksijini yeSinglet)', litshabalalise umhlaza ngaphakathi njengebhombu eqhumayo.
💬 Kutheni usithi masingaphumi elangeni (Photosensitivity) emva kolu gonyo?
Le yeyona ngxaki iyingozi neyona inkulu ngolu nyango! Eli yeza alihlali nje kuphela kumhlaza kodwa nakwisikhumba/kwizicwili. Ngoko ke, ukuba ujongene 'nelanga (ilanga) okanye iibhalbhu zokukhanya ezinamandla' iintsuku ezingama-30-90 (inyanga e-1-3) emva kolu nyango, lonke ulusu/umzimba wakho uya kutsha ngokungathi utsha (Severe Photosensitivity Reaction)! Ngoko ke, kunyanzelekile ukuba uhlale kwigumbi/ingubo emnyama ukuze ugqume umzimba ngokupheleleyo.
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