Ngaba ugqirha wakho ukunike umyalelo wena okanye umntu osapho lwakho ukuba niqale ukusebenzisa iyeza iRituximab? Kuqhelekile ukuba uzive usoyika kwaye unomdla xa usiva igama leyeza elinamandla kangaka. "Kuza kwenzeka ntoni ngale nto?", "Ndifanele ndixhalabele ntoni?", njl. Mhlawumbi unemibuzo emininzi engqondweni yakho. Yiyo loo nto, namhlanje, siza kuthetha ngokulula nangokunobuhlobo ngale chiza iRituximab, into eliyenzayo, kunye nezinto ekufuneka uzixhalabele xa ulisebenzisa.
Ngamafutshane, yintoni iRituximab?
I-Rituximab liyeza elikhethekileyo kakhulu elikudidi lwamayeza abizwa ngokuba yi-monoclonal antibodies. Cinga ngayo njengeproteni eyenziwe ngokukodwa kwilebhu ukunceda inkqubo yokuzikhusela yomzimba wethu (inkqubo yokuzikhusela). Umsebenzi wayo ophambili kukubona nokuhlasela nokutshabalalisa ezinye iiseli ezingaqhelekanga emzimbeni wethu, ingakumbi iiseli zomhlaza. Ikwanceda ukulawula ezinye izifo ezibangelwa kukungasebenzi kakuhle kwenkqubo yokuzikhusela yomzimba.
Kukho iimeko ezahlukeneyo apho eli yeza lisetyenziswa khona kakhulu.
| Udidi lwezifo | Igama lesifo |
|---|---|
| Iintlobo zeMihlaza | I-lymphoma engeyiyo iHodgkin |
| I-leukemia ye-lymphocytic engapheliyo (CLL) | |
| Izifo ezichaphazela umzimba | Irheumatoid arthritis |
| I-Granulomatosis ene-polyangiitis | |
| I-Microscopic polyangiitis | |
| I-Pemphigus vulgaris - imeko yolusu |
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale unyango
Oku kubaluleke kakhulu. Ukuze ukhuseleke, ngokuqinisekileyo kufuneka uxelele ugqirha wakho ukuba unayo nayiphi na kwezi meko zilandelayo ngaphambi kokuba uqale unyango.
- Intlungu yesifuba okanye isifo sentliziyo: Ukuba unesifo sentliziyo okanye ukhe waneentlungu zesifuba ngaphambili.
- Iintsholongwane: Naziphi na izifo ezikhoyo ngoku, ingakumbi izifo ezibangelwa ziintsholongwane ezifana ne-chickenpox, i-herpes, kunye ne-hepatitis B.
- Ubuthathaka benkqubo yomzimba yokuzikhusela: Ukuba uneengxaki ngenkqubo yakho yokuzikhusela komzimba.
- Ukubetha kwentliziyo okungaqhelekanga: Ukuba ukubetha kwentliziyo akuqhelekanga.
- Isifo sezintso: Ukuba unayo nayiphi na imeko enxulumene nezintso.
- Inani eliphantsi leeseli zegazi: Ukuba kukho iingxelo zokuba iiseli ezimhlophe zegazi, iiplatelets, okanye iiseli ezibomvu zegazi ziphantsi egazini.
- Isifo semiphunga: Ukuba unesifo semiphunga.
- Ukugonywa: Ukuba usandul’ ukufumana ugonyo okanye uceba ukulufumana kwixesha elizayo.
- Ii-Allergy: Ukuba une-allergy kwi-Rituximab, okanye nakweyiphi na enye iyeza, ukutya, okanye idayi.
- Ukukhulelwa okanye ukuncancisa: Ukuba ukhulelwe, uzama ukukhulelwa, okanye uncancisa.
Eli yeza linikwa njani emzimbeni?
Eli yeza alikho into onokuyisebenzisa ekhaya. Linikwa ngugqirha okanye umongikazi oqeqeshiweyo esibhedlele okanye eklinikhi njengokufakwa emthanjeni. Le nkqubo ingathatha iiyure ezininzi.
Eyona nto ibalulekileyo kukuya esibhedlele ngomhla omiselweyo ukuze ufumane unyango. Ukuba ngesizathu esithile awukwazi ukuya ngomhla omiselweyo, qiniseka ukuba ufowunela ugqirha wakho kwaye umazise.
Kwanasebantwaneni, eli yeza linikwa kwiimeko ezithile ezikhethekileyo (umzekelo, abantwana abangaphezu kweenyanga ezi-6 ubudala). Kodwa lenziwa ngononophelo olukhulu kwaye kuphela ngokwengcebiso kagqirha okhethekileyo.
Kuthekani ukuba ndithatha amayeza amaninzi kakhulu?
Oku kubonelelwa esibhedlele, ngoko ke amathuba okuba oku kwenzeke mancinci kakhulu. Nangona kunjalo, ukuba ukrokrela ukuba usele kakhulu, yixele ngoko nangoko kwiCandelo loNyango oluNgxamisekileyo (ETU) lesibhedlele. Okanye, ungatsalela umnxeba iZiko loLwazi lweePoison kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Izinto ekufuneka uzilumkele ngakumbi xa usebenzisa amayeza
- Ukhuseleko kwizifo:Eli yeza linokuthoba amasosha omzimba wakho, linyuse umngcipheko wakho wokugula nosulelo. Ke ngoko, ukuba ufumana iimpawu ezifana nomkhuhlane, umkhuhlane, okanye umphimbo obuhlungu, musa ukuzinyanga kwaye uxelele ugqirha wakho. Kuphephe ukuya kwiindawo ezinabantu abaninzi kwaye udibane nabantu abagulayo kangangoko unako.
- Utshintsho lolusu: Ngamanye amaxesha, nokuba ziiveki emva kokuba uqalile amayeza, ulusu lunokusabela kakhulu. Ukuba uvelisa amadyungudyungu abomvu okanye amfusa, izilonda, ulusu oluxobukayo, okanye umkhuhlane, xelela ugqirha wakho ngoko nangoko.
- Iimpendulo zokufakwa kwenaliti: Abanye abantu banokuba neempendulo ze-allergy xa iyeza linikwa ngemithambo yegazi. Ukunciphisa oku, ugqirha wakho angakunika amanye amayeza (umz., iPanadol, iPyridoxine) ngaphambi kokuba ufakwe inaliti. Ukuba uziva ungakhululekanga ngexesha lokufakwa kwenaliti, xelela umongikazi okanye ugqirha ngoko nangoko.
- Ukukhulelwa nokuncancisa: Oku kubaluleke kakhulu. Kufuneka uphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye emva kweenyanga ezili-12 uyeke unyango . Thetha nogqirha wakho malunga nokusebenzisa ucwangciso lokuzala. Kwakhona, gwema ukuncancisa iinyanga ezi-6 emva kokuyeka unyango .
- Iziphumo ezinokubakho engqondweni: Amaxesha amaninzi, abanye abaguli banokuba nosulelo olukhulu oluchaphazela ingqondo ngenxa yale yeza. Xelela ugqirha wakho ngokukhawuleza ukuba ufumana naluphi na utshintsho okanye iingxaki ngokubona kwakho, ukucinga, ukuthetha, ukuhamba, okanye ukuma .
Iziphumo ebezingalindelekanga zeyeza
Njengalo naliphi na iyeza, iRituximab inokubangela iziphumo ebezingalindelekanga. Nangona kunjalo, ayinguye wonke umntu ozifumanayo. Makhe sizijonge ngokusondeleyo kwitheyibhile engasezantsi.
| Ulwahlulo lweziphumo ebezingalindelekanga zeRituximab | |
|---|---|
| Iziphumo ebezingalindelekanga ekufuneka zixelwe kugqirha wakho ngoko nangoko | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela; ukudumba kobuso, imilebe, ulwimi. |
| Iimpawu zosulelo | Umkhuhlane, ukubanda, ukukhohlela, umphimbo obuhlungu, usulelo lomchamo. |
| Iimpawu zokuhlaselwa yintliziyo | Ubunzima bokuphefumla; intlungu okanye ukuqina esifubeni, entanyeni, emqolo, okanye ezingalweni. |
| Ukudumba komzimba (i-Edema) | Ukutyeba ngequbuliso; ukudumba kwamaqatha, iinyawo, izandla; ubunzima bokuphefumla. |
| Umonakalo wezintso | Ukuncipha okanye utshintsho kubungakanani bomchamo ophumayo. |
| Umonakalo wesibindi | Umchamo otyheli/omdaka omnyama, ukutyheli kwamehlo okanye ulusu, iintlungu kwinxalenye ephezulu ngasekunene yesisu, ukungabi namdla wokutya. |
| Iimpendulo ezinzulu zesikhumba | Ubomvu, amadyungudyungu, ukuxobuka kolusu (nangaphakathi emlonyeni). |
| Ukopha okungaqhelekanga | Ukugruzuka okanye ukopha kolusu ngaphandle kwesizathu. |
| Izinto ezingaqhelekanga ukuba zimbi, kodwa kufuneka zixelwe kugqirha ukuba ziyaqhubeka | |
| Intloko ebuhlungu | Intloko ebuhlungu eqhelekileyo. |
| Intlungu yamalungu | Intlungu yamalungu. |
| Intlungu yemisipha | Ukuqhaqhazela kwemisipha okanye intlungu. |
| Isicaphucaphu | Ukuziva ngathi uhlanza. |
Amanye amayeza anokusebenzisana neRituximab (i-Interactions)
Kubaluleke kakhulu ukuxelela ugqirha wakho malunga nawo onke amayeza owasebenzisayo (kuquka iivithamini kunye namayeza esintu). Izinto ezinokuthi zisebenzise iRituximab ziquka:
- Iigonyo eziphila: Ufanele ukuphephe ukufumana iigonyo eziphila ngelixa usebenzisa eli yeza.
- I-Cisplatin: I-Rituximab inokunxibelelana ne-Cisplatin, elinye iyeza lomhlaza.
Olu luhlu aluphelelanga, ngoko ke nceda wazise ugqirha wakho ngayo yonke into oyithathayo.
Umyalezo Wokuya Ekhaya
- I-Rituximab liyeza elinamandla nelikhethekileyo elinikwa esibhedlele lomhlaza kunye nezifo zenkqubo yomzimba yokuzikhusela.
- Ngaphambi kokuba uqale unyango, xelela ugqirha wakho ngazo zonke iimeko zakho zempilo kunye namayeza owasebenzisayo.
- Qaphela iimpembelelo zokufakwa kweyeza kunye neempawu zosulelo (umkhuhlane, ukukhwehlela) xa usebenzisa iyeza.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ufumana isiphumo esibi esifana nokudumba kwesikhumba, ubunzima bokuphefumla, okanye iintlungu zesifuba.
- Kubalulekile ukuphepha ukukhulelwa nokuncancisa (iinyanga ezi-6) ngexesha lonyango kwaye kangangoko ugqirha wakho ecebisa (iinyanga ezili-12).
- Kubaluleke kakhulu ukuya kwiindibano zakho zonyango ngaphandle kokuphoswa ziindibano.
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