Ngaba wakha waziva iqhuma elincinci emzimbeni wakho, mhlawumbi emlenzeni okanye engalweni yakho? Ekuqaleni, usenokuba wacinga, "Owu, oku kukudumba nje okuncinci." Ekubeni kungekho ntlungu, usenokuba awuzange uyinike ingqalelo kangako. Kodwa ukuba ayipheli emva kweentsuku ezimbalwa, kuyinto eqhelekileyo ukuziva ukhathazekile kancinci. Yiyo loo nto kungengombono ulungileyo ukungawunaki wonke umhluma obonakala emzimbeni wakho. Namhlanje, siza kuthetha ngomhlaza ongaqhelekanga onokuthi uqale njengeqhuma elingenabuhlungu. Yiyo loo nto yiSynovial Sarcoma.
Ngamafutshane, yintoni iSynovial Sarcoma?
I-Synovial Sarcoma luhlobo olungaqhelekanga lomhlaza oluchaphazela izicubu ezithambileyo zomzimba wethu, njengemisipha okanye imisipha . Igama layo livela kuba iiseli zomhlaza zifana neeseli ze-synovial ezikumalungu ethu. Njengeeseli ezingaphakathi kwamalungu ethu njengeengqiniba zethu, izinqe, namagxa.
Enye yeempawu zalo mhlaza kukuba ukhula kancinci kakhulu . Yiyo loo nto usenokungaziva ntlungu kwasekuqaleni. Kubantu abaninzi, iimpawu ziqala ukubonakala emva kokuba ithumba likhule ngokwaneleyo ukuba libonwe okanye livakale. Ngamanye amaxesha, ukuba umthambo okufutshane ucinezelwe njengoko ithumba likhula, unokubangela intlungu okanye ukungaziva kuloo ndawo.
Kuqhelekile ukuba nabani na azive ngathi ihlabathi lakhe lonke lijika ngequbuliso xa efumanisa ukuba unomhlaza. "Kuza kuthetha ukuthini oku kum?", "Ubomi bam buza kuba njani ukususela ngoku?" Usenokuba nemibuzo emininzi engqondweni yakho. Awuwedwa, kwaye ezi mvakalelo ziqhelekile. Ugqirha wakho kunye neqela lakho lezonyango banawe kuyo yonke inyathelo.
Lo mhlaza ungakhula kumalungu aphi emzimbeni?
Olu hlobo lomhlaza lunokwenzeka kwiindawo ezahlukeneyo zomzimba. Ezona zixhaphakileyo zezi:
- Isisu
- Izandla
- Iinyawo
- Imilenze
- Imiphunga
Ukongeza, lo mhlaza unokubakho nasemalungeni ethu. Umzekelo:
- Amaqatha
- Iingqiniba
- Izinqe
- Amagxa
- Izandla
Kunqabile kakhulu ukuba i-synovial sarcoma ivele esifubeni, entloko, okanye entanyeni.
Ixhaphake kangakanani le meko?
Njengezinye ii-sarcomas zezicubu ezithambileyo, i-synovial sarcoma ngumhlaza ongaqhelekanga . Nangona inokwenzeka nakweyiphi na iminyaka, ixhaphake kakhulu kumadoda angaphantsi kweminyaka engama-30 .
Ziziphi iimpawu eziphambili zalo mhlaza?
I-Synovial Sarcoma ngumhlaza okhula kancinci. Ngamanye amaxesha, ithumba linokuhlala emzimbeni ukuya kuthi ga kwiminyaka emibini ngaphandle kokubangela naziphi na iimpawu. Xa kuvela iimpawu, unokuqaphela:
| Uphawu | Inkcazo |
|---|---|
| Iqhubu elibonakalayo okanye eliqondakalayo | Olu lolona phawu luqhelekileyo. Into ekhethekileyo kukuba uninzi lwexesha, eli qhuma alinantlungu. |
| Ukuba ndindisholo | Njengoko iqhuma likhula, linokubangela uxinzelelo kumthambo okufutshane. |
| Intlungu | Nangona kusenokungabikho ntlungu ekuqaleni, intlungu inokubakho njengoko iqhuma likhula okanye licinezela umthambo. |
| Ukudumba | Ungaphawula ukudumba kwindawo apho kukho iqhuma. |
Ezi mpawu zinokufana nezezinye izifo ezingabalulekanga kangako, ezifana ne-arthritis okanye i-bursitis, ezinokuthi ngamanye amaxesha zilibazise ukuxilongwa.
Ngoko ke khumbula, ukuba ubona iqhuma elitsha emzimbeni wakho, nokuba alibuhlungu, kwaye sele likhona kangangeeveki ezingaphezu kwezimbini, kungcono ukubona ugqirha uze ulihlole. Leyo yeyona nto ilungileyo onokuyenza.
Kutheni le nto lo mhlaza uvela? Yintoni unobangela?
Abaphandi abakafumani sizathu sithile soku, kodwa bayazi ukuba kubangelwa lutshintsho oluthile (utshintsho) kwiichromosomes zethu.
Cinga nje ngale ndlela. Iichromosomes zethu zifana nencwadi enkulu. Iigenes ngamazwi abhalwe kuloo ncwadi. Kuphela xa la magama elandelelana ngokuchanekileyo apho iiseli emzimbeni wethu zisebenza ngokufanelekileyo. Xa i-synovial sarcoma ikhula, ezi chromosomes ziyaqhekeka kwaye xa zihlanganiswa kwakhona, ezinye iigenes zinamathela kwiindawo ezingafanelekanga. Ngokukodwa, igene ebizwa ngokuba yi-'SYT' ixubana nezinye iigenes ezingahambelani nayo. Ngenxa yoku kuphazamiseka, umyalezo ofunyanwa ziiseli awuchanekanga. Emva koko iiseli ziqala ukwahlukana ngokungalawulekiyo, zenze ithumba elinomhlaza.
Ugqirha uxilonga njani esi sifo?
Xa usiya kugqirha, uza kuqala akuhlole umzimba, akubuze ngeempawu zakho kunye nembali yempilo yakho. Ukuba unamathandabuzo, uza kukuthumela kwingcali yomhlaza.
Ingcali iza kwenza uvavanyo olwahlukeneyo ukuze ifumanise ubungakanani obuchanekileyo kunye nendawo yeqhuma.
| Uvavanyo | Wenza ntoni ngayo? |
|---|---|
| Ii-X-reyi | Ungajonga ukuba iqhuma lichaphazele amathambo na. |
| Iskeni se-MRI (Umfanekiso weMagnetic Resonance) | Imifanekiso ecacileyo kakhulu yethumba kunye nezicubu ezithambileyo ezijikeleze lona inokufumaneka. |
| Iskeni ye-ultrasound | Kuyanceda ekuchongeni ekuqaleni ukuba iqhuma liqinile okanye lizele lulwelo. |
| I-CT Scan (i-Computed Tomography) | Oku kubalulekile ukuze kubonwe ukuba umhlaza usasazeke na kwezinye iindawo zomzimba (umz., imiphunga). |
Emva kwezi mvavanyo, uvavanyo olubaluleke kakhulu oluqinisekisa ngokupheleleyo isifo yi-biopsy.Okwenziwayo apha kukuthatha iqhekeza elincinci kakhulu lesicwili kwiqhubu lize lithunyelwe kwilebhu. Apho, ingcali yezifo ihlola iiseli phantsi kwe-microscope ukuqinisekisa ukuba ingaba ngumhlaza na, kwaye ukuba kunjalo, loluphi uhlobo lomhlaza.
Zithini iindlela zonyango zoku?
Unyango oluphambili noluqhelekileyo lwe-synovial sarcoma lutyando . Injongo kukususa ngokupheleleyo ithumba elinomhlaza. Ithumba lisuswa kunye nenani elincinci lezicubu eziphilileyo ezijikeleze lona ukuze kususwe naziphi na iiseli zomhlaza eziseleyo. Kwezinye iimeko, kuxhomekeke ekubeni umhlaza usasazeke kangakanani, umsipha wonke okanye iqela lemisipha kunokufuneka lisuswe. Ugqirha wakho uya kukuchazela oku ngokusekelwe kwimeko yakho.
Utyando lungenziwa njengonyango olunye okanye ludityaniswe nezinye iindlela zonyango. Ezi ndlela zonyango zezi:
- Unyango lweKhemotherapy: Ukunika amayeza abulala iiseli zomhlaza.
- Unyango lweMisebe: Ukutshabalalisa iiseli zomhlaza kusetyenziswa imisebe enamandla aphezulu.
- Unyango lwe-Immunotherapy: Ukuvuselela amasosha omzimba wethu ukuze alwe neeseli zomhlaza.
- Unyango olujoliswe kuko: Ukunika amayeza ajolise kwiimolekyuli ezithile ezichaphazela ukukhula kweeseli zomhlaza.
- Amayeza okulwa ne-angiogenesis: La mayeza asebenza ngokuthintela ukwakheka kwemithambo yegazi emitsha enika iiseli zomhlaza igazi. Oku ke kuncitshisa iiseli zomhlaza izondlo kwaye kubangele ukuba zife.
Unyango olulungele wena luxhomekeke kwizinto ezininzi, kuquka ubungakanani bethumba, indawo elikuyo, ixesha olichithe unalo, kunye nokuba umhlaza usasazeke na kwezinye iindawo (ezinokwahlulwahlulwa).
Yintoni onokuyilindela emva konyango?
Ngokuhambela phambili kwesayensi yezonyango, kubekho inkqubela phambili enkulu kunyango lweSynovial Sarcoma. Nangona kunjalo, kukho umngcipheko wokuba umhlaza uphinde ubuye emva konyango, ngamanye amaxesha nasemva kweminyaka. Ke ngoko, ugqirha wakho uza kukujonga rhoqo emva kweminyaka eliqela emva konyango.
Xa kufikwa kumanqanaba okusinda komhlaza, izinga lokusinda kweminyaka emi-5 limalunga nama-50% - 60%. Oku kuthetha ukuba abantu aba-5 okanye aba-6 kwaba-10 abafunyaniswe benesifo basaphila emva kweminyaka emi-5. Kubaluleke kakhulu ukubuza ugqirha wakho ukuba ezi zibalo zisebenza njani kuwe kwaye imeko yakho injani.
Ngaba ikho indlela yokuthintela oku ukuba kungenzeki?
Ngelishwa, oku akunakuthintelwa kuba kubangelwa lutshintsho kwiichromosomes esingenakukwazi ukuzilawula.
Kodwa, eyona nto ingcono esinokuyenza kukuthintela umhlaza ukuba ungasasazeki kwezinye iindawo zomzimba (i-metastasis) . Eyona ndlela yokwenza oko kukufumanisa isifo kwangethuba kwaye uqale unyango ngokukhawuleza . Ngoko ke, soloko uqaphela utshintsho emzimbeni wakho. Ukuba ubona iqhuma elitsha elingasukiyo kwiiveki ezimbalwa, qiniseka ukuba ulibonisa ugqirha.
Umyalezo Wokuya Ekhaya
- I-Synovial sarcoma luhlobo olungaqhelekanga lomhlaza oluvela kwizicubu ezithambileyo. Idla ngokuqala njengeqhubu elingenabuhlungu .
- Le meko ixhaphake kakhulu kubantu abaselula, ingakumbi amadoda angaphantsi kweminyaka engama-30 ubudala .
- Ukuba uneqhuma elitsha emzimbeni wakho kwaye sele likhona kangangeeveki ezingaphezu kwezimbini, musa ukuba buvila okanye ukoyika, kwaye ngokuqinisekileyo bonana nogqirha.
- Okukhona isifo sifunyanwa ngokukhawuleza, kokukhona unyango luya kuphumelela. Leyo yeyona ndlela ilungileyo yokuthintela ukusasazeka komhlaza.
- Kukho unyango olusebenzayo koku, olufana notyando, i-chemotherapy, kunye nonyango lwe-radiation. Kwakhona, ukulandelelana okufanelekileyo kwezonyango kubalulekile nasemva konyango.
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