Ngaba ugqirha wakho ukhe wakunika iVorinostat okanye umntu othile kusapho lwakho? Ekubeni eli liyeza elikhethekileyo elisetyenziselwa ukunyanga umhlaza, usenokuba nemibuzo, umdla, mhlawumbi noloyiko oluncinci. Yinto eqhelekileyo leyo. Ungakhathazeki. Kweli nqaku, siza kuthetha ngeli yeza, into eliyenzayo, kunye nento ekufuneka uyiqaphele.
Loluphi uhlobo lonyango iVorinostat?
Ngamafutshane, iVorinostat liyeza le-chemotherapy . Kodwa alifani neyeza lomhlaza esilifumana esibhedlele nge-saline. Li-capsule oyithatha ngomlomo.
Eli yeza lisetyenziselwa ngokukodwa ukunyanga uhlobo lomhlaza oluvela eluswini olubizwa ngokuba yi -cutaneous T-cell lymphoma (CTCL) . Lisenokuvakala linzima kancinci, kodwa luhlobo nje lomhlaza oluchaphazela ulusu. Ugqirha wakho uhlala ekunika eli yeza phantsi kwegama elithi Zolinza.
Izinto ekufuneka uzixelele ugqirha wakho ngaphambi kokuba uqale eli yeza
Ngaphambi kokuba uqalise eli yeza, kubaluleke kakhulu ukuxoxa ngembali yakho yempilo epheleleyo nogqirha wakho. Oku kungenxa yokuba ezinye iimeko zonyango zifuna unonophelo olukhethekileyo xa usebenzisa eli yeza. Ngokukodwa, qiniseka ukuba uxelele ugqirha wakho ukuba unayo:
- Ukuba unesifo seswekile
- Ukuba unembali yokuqhekeka kwegazi
- Ukuba unemibuzo malunga nokubetha kwentliziyo okungaqhelekanga
- Ukuba unesifo sesibindi
- Ukuba uthatha amanye amayeza athintela okanye anyanga amahlwili egazi (afana ne-warfarin)
- Ukuba ukhe waba ne-allergy kwi-Vorinostat okanye naliphi na elinye iyeza, ukutya, okanye idayi.
- Ukuba uzama ukukhulelwa okanye sele ukhulelwe
- Ukuba umama uncancisa umntwana wakhe
Indlela yokusebenzisa amayeza ngokuchanekileyo?
Indlela osebenzisa ngayo eli yeza ibaluleke kakhulu. Njengoko ugqirha etshilo, ukulithatha ngexesha elifanelekileyo yeyona ndlela ilungileyo yokufumana iziphumo ezilungileyo.
- Le yikhaphu efanele ithathwe neglasi yamanzi.
- Kubaluleke kakhulu ukusela eli yeza xa usitya . Oku kuya kunciphisa umngcipheko wokungakhululeki esiswini.
- Ungaze uhlafune, utyumze, okanye uvule ikhaphu uze usele umgubo ongaphakathi. Ikhaphu mayiginywe yonke.
- Musa ukusela ngaphezu kokuba ugqirha ekuxelele, kwaye ungayeki de akuxelele ukuba uyeke.
Kuthekani ukuba ndisebenzisa i-overdose?
Khawucinge ukuba ngempazamo usele idosi engaphezulu kweyamiselweyo. Ukuba oku kuyenzeka, ungoyiki kwaye uye kwiSebe lezeMpilo eziNgxamisekileyo (ETU) elikufutshane nawe ngoko nangoko .Fowunela iZiko loLwazi ngeTyhefu leSizwe kwiSibhedlele sikaZwelonke saseColombo ukuze ufumane ingcebiso.
Kuthekani ukuba ndilibele ukusela amayeza am?
Yintoni omawuyenze ukuba ulibele ukusela amayeza akho? Thatha idosi oyiphosileyo kwangoko xa ukhumbula. Nangona kunjalo, ukuba sele kuza kufuneka uthathe idosi elandelayo, yitsibe idosi oyiphosileyo uze uthathe idosi elandelayo ngexesha elicwangcisiweyo. Ungaze uthathe iidosi ezimbini ngaxeshanye (idosi ephindwe kabini).
Eli liyeza elimiselwe wena kuphela. Musa ukunika omnye umntu eli yeza nangasiphi na isizathu.
Amanye amayeza anokusebenza kunye nale mayeza
I-Vorinostat inokubangela iimpembelelo eziyingozi xa isetyenziswa kunye namanye amayeza athile. Ngoko ke, kubaluleke kakhulu ukuxelela ugqirha wakho ngawo onke amayeza owasebenzisayo (kuquka iivithamini, iimveliso zezityalo, kunye nezithomalalisi zentlungu).
La mayeza alandelayo akufuneki asetyenziswe kunye neVorinostat:
* i-cisapride
* idronedarone
* i-pimozide
* i-thioridazine
Ukongeza, kukho amanye amayeza anokusebenzisana nale. Ngoko ke ukuba uthatha naliphi na kula mayeza, yazisa ugqirha wakho:
- Ezinye iintlobo zee-antibiotics: ezifana ne-`clarithromycin`, `erythromycin`, `levofloxacin`, `mefloquine`.
- Amayeza okudakumba, ixhala, okanye ezinye izifo zengqondo.
- Amayeza okunceda abantu abanengxaki yentliziyo.
- Amayeza anjenge-valproic acid (iyeza lokuxhuzula ).
- Amayeza athintela ukujiya kwegazi: afana ne-`warfarin`, `enoxaparin`, `heparin`.
- Ezinye iindlela zonyango lomhlaza: ezifana ne-`dasatinib`, `lapatinib`.
- Amanye amayeza achaphazela izinga lentliziyo (andisa ixesha le-QT).
Olu luhlu aluphelelanga. Ngoko ke xelela ugqirha wakho ngazo zonke iziyobisi ozisebenzisayo, ukuba uyatshaya, okanye ukuba usela utywala.
Amanqaku akhethekileyo ekufuneka uwaqaphele xa usebenzisa amayeza
Kukho izinto ezimbalwa ekufuneka uziqwalasele ngokukodwa xa usebenzisa eli yeza.
- Uvavanyo lweGazi: Kubalulekile ukuba uvavanyo lwegazi rhoqo njengoko ugqirha wakho ekuyalele ngelixa usebenzisa eli yeza. Oku kuya kunceda ekujongeni indlela eli yeza elichaphazela ngayo umzimba wakho, ingakumbi amanqanaba akho e-potassium kunye ne-magnesium kunye neeseli zegazi.
- Sela amanzi amaninzi: Sela amanzi amaninzi imini yonke. Kubaluleke kakhulu ukuthintela ukuphelelwa ngamanzi emzimbeni. Buza ugqirha wakho malunga nobungakanani bamanzi omele uwasele ngosuku.
- Iikhaphu zamayeza ngononophelo:Ukuba ikhaphu yeyeza iyaphuka okanye umgubo ongaphakathi uyachitheka, musa ukuwuchukumisa umgubo okanye uwuvumele udibane namehlo okanye ulusu lwakho. Ukuba uyaphuma, hlamba loo ndawo ngesepha namanzi ngoko nangoko. Ukuba ingena emehlweni akho, hlambulula kakuhle ngamanzi uze ubize ugqirha ngoko nangoko.
- Ukukhulelwa nokuncancisa: Le yingxaki enkulu.
- Ukuba ungumfazi, kuphephe ukukhulelwa ngelixa usebenzisa eli yeza kwaye ubuncinane iinyanga ezi-6 emva kokuyeka ukusebenzisa eli yeza.
- Ukuba uyindoda, musa ukuba nguyise womntwana ngelixa usebenzisa eli yeza kwaye ubuncinane iinyanga ezi-3 emva kokuyeka ukusebenzisa eli yeza.
- Eli yeza linokubangela ingozi enkulu kusana olungekazalwa. Cela ugqirha wakho ukuba akunike ulwazi oluthe kratya ngalo mba.
- Ukuba ungumama oncancisayo, musa ukuncancisa umntwana wakho ngelixa usebenzisa eli yeza kwaye ubuncinane iveki emva kokuba uyekile.
- Ukuzala: Eli yeza lisenokuchaphazela ukuzala kwakho. Ukuba uneengxaki malunga noku, thetha nogqirha wakho ngaphambi kokuba uqale unyango.
Iziphumo ebezingalindelekanga ezinokubakho ngenxa yamayeza
Njengalo naliphi na iyeza, iVorinostat inokubangela iziphumo ebezingalindelekanga. Ezinye zinzima, ngelixa ezinye zincinci. Eyona nto ibalulekileyo kukwazi ezi mpawu kwaye uxelele ugqirha wakho ngokukhawuleza ukuba uhlangabezana nazo.
| Uhlobo lwesiphumo esibi | Iimpawu |
|---|---|
| Iimpawu ezinzulu ezifuna ukuthunyelwa ngokukhawuleza kugqirha wakho okanye kwiSebe likaXakeka (ETU) | |
| Iimpendulo ze-allergy | Ukurhawuzelela kwesikhumba, ukurhawuzelela okukhulu, ukudumba kobuso, imilebe okanye ulwimi. |
| Uxinzelelo lokuphefumla kunye neempawu zesifo sentliziyo | Ubunzima bokuphefumla, iintlungu esifubeni, ukubetha kwentliziyo ngokukhawuleza okanye ngokungangqalanga. |
| Iimpawu zokuqhekeka kwegazi | Intlungu, ukudumba, kunye nokubomvu emlenzeni (ngokudla ngokuba ngumlenze omnye). |
| Ezinye iimpawu ezinzulu | Isicaphucaphu, ukuhlanza, umkhuhlane, ukubanda, umphimbo obuhlungu, ukopha okanye ukukrweleka okungaqhelekanga, ukudinwa kakhulu, ubunzima bokuhamba okanye ukuthetha, ukudumba kwemilenze. |
| Iimpawu eziqhelekileyo ekufuneka zixelwe kugqirha ukuba ziyaqhubeka okanye ziyakhathaza | |
| Iingxaki zenkqubo yokugaya ukutya | Urhudo, ukuqhina, isicaphucaphu, ukuhlanza, ukungakhululeki esiswini. |
| Ezinye iimpawu ngokubanzi | Utshintsho kwincasa, umlomo owomileyo, intloko ebuhlungu, ukuphelelwa ngumdla wokutya, iintlungu zemisipha. |
Ungayigcina njani imithi ikhuselekile?
- Gcina amayeza evaliwe kwaye angafikeleleki kwaye angabonwa ngabantwana abancinci .
- Gcina kubushushu begumbi (phakathi kwe-15 kunye ne-30 degrees Celsius). Musa ukugcina kwiindawo ezinomswakama ophezulu, njengakwigumbi lokuhlambela.
- Lahla amayeza aphelelwe lixesha ngaphandle kokuwasebenzisa.
Umyalezo Wokuya Ekhaya
- I-Vorinostat liyeza elisetyenziselwa ukunyanga uhlobo lomhlaza olubizwa ngokuba yi-CTCL. Soloko uthatha eli chiza njengoko ugqirha wakho ekuyalele.
- Xelela ugqirha wakho ngazo zonke ezinye iziyobisi ozisebenzisayo kunye nazo zonke iimeko zempilo onazo.
- Ginya iyeza liphelele xa usitya. Musa ukulihlafuna, ukulityumza, okanye ukulivula ikhapsuli.
- Kufuneka ulumke kakhulu xa usebenzisa eli yeza ngexesha lokukhulelwa, ngelixa uncancisa, kwaye ukuba ulindele umntwana. Landela imiyalelo kagqirha wakho.
- Funa uncedo lwezonyango ngokukhawuleza ukuba ufumana iziphumo ebezingalindelekanga ezinzulu ezifana nobunzima bokuphefumla, iintlungu zesifuba, okanye ukopha okungaqhelekanga.
- Ukuba unemibuzo okanye unenkxalabo, ungoyiki ukuthetha nogqirha wakho. Lilungelo lakho ukubuza imibuzo malunga nempilo yakho.
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