Xa umntu efumana utyando olutsha lwezintso, kufana nokufumana ubomi obutsha. Kodwa emva kotyando olukhulu kangaka, ngamanye amaxesha kunokuvela iingxaki ezingalindelekanga. Umzekelo, usulelo olunzima olunokwenzeka kumntu oye wafakelwa izintso lubizwa ngokuba yi-BK Viral Nephritis. Oku kunokuchaphazela ukusebenza kwezintso zakho ezintsha kwaye kuthintele impumelelo yokufakelwa. Kodwa ungakhathazeki, ukuba siyazi kakuhle oku, kukho iindlela zokuzikhusela kule meko. Ngoko ke, masithethe ngale nto ngokweenkcukacha namhlanje.
Yintoni le ntsholongwane ye-BK?
Ngamafutshane, i-BK virus nephritis lusulelo oluyingozi olubangelwa kukuvuselelwa kwe-BK polyomavirus, ebingasasebenzi (ifihlwe) emzimbeni wakho emva kokufakelwa izintso. Le ntsholongwane yafunyanwa okokuqala ngo-1971 kwisigulana esafakelwa izintso esinegama elithi "BK." Yiyo loo nto ibizwa ngokuba yi-BK virus.
Intsholongwane ye-BK ngokwenene lusulelo oluxhaphakileyo, oludla ngokungabonisi zimpawu, olusasazeka ngokukhupha okufana nencindi. Umntu ophilileyo akaziva nokuba usulelekile yile ntsholongwane. Nangona kunjalo, xa intsholongwane ingena emzimbeni, inokuhlala ingasebenzi emizimbeni yethu ubomi bethu bonke, ngaphandle kokubangela naziphi na iingxaki.
Uphando lubonisa ukuba ngaphezulu kwama-80% abantu behlabathi banee-antibodies ezilwa nale ntsholongwane. Oku kuthetha ukuba phantse sonke siye sachaphazeleka yile ntsholongwane sisebancinci. Umntu oqhelekileyo ongafakelwanga izintso akayi konakaliswa yile ntsholongwane emzimbeni wakhe.
Oku kungaba yingozi njani kumntu oye wafakelwa izintso?
Emva kokuba utyando lwezintso, uza kunikwa amayeza akhethekileyo okuthintela umzimba wakho ukuba ungalamkeli izintso ezintsha. La mayeza abizwa ngokuba ngamayeza okulwa nokungavumi kunye namayeza okunciphisa umzimba . La mayeza asebenza ngokwenza buthathaka inkqubo yomzimba wakho yokuzikhusela. Oku kuvumela izintso ezintsha ukuba zilungelelane nomzimba wakho ngaphandle kokuhlaselwa.
Kodwa xa inkqubo yakho yomzimba yokuzikhusela ibuthathaka, amandla omzimba wakho okulwa nezinye izifo nawo ayancitshiswa. Ngelo xesha, intsholongwane ye-BK ebilele emzimbeni wakho "iyavuka," oko kuthetha ukuba iyasebenza kwakhona.
Le ntsholongwane isebenzayo ihlasela ngqo izintso zakho ezintsha. Oku kubangela ukudumba, okanye ukudumba kwezintso kunye nee-ureters. Oku kubizwa ngokuba yi-nephritis .
Oku kuqaqanjelwa kubangela ukuba izintso zingasebenzi kakuhle kancinci kancinci. Xa le meko iba mandundu ngakumbi, ibizwa ngokuba yi -BK virus nephropathy.Ibizwa ngokuba yi-nephropathy. Oku kuthetha ukuba izintso zonakele kakhulu, kwaye ekugqibeleni zisenokungasebenzi ngokupheleleyo. Kuqikelelwa ukuba malunga ne-2% yabantu abafumana ukufakelwa kwezintso bahlakulela le nephropathy.
Zithini iimpawu ze-BK Viral Nephritis?
Ixesha elininzi, abantu abanale ntsholongwane ababonisi zimpawu. Nangona kunjalo, xa kuvela iimpawu, kufuneka uqaphele ezi zinto zilandelayo.
| Uphawu | Inkcazo |
|---|---|
| Utshintsho kumchamo | Igazi kumchamo okanye kumchamo ojika ube bomvu-mdaka. |
| Ubunzima bokuchama | Intlungu okanye ukutsha xa uchama, ubunzima bokuchama. |
| Isinyi asiphumi ngokupheleleyo | Ukuziva ngathi kusekho umchamo emva kokuchama. |
| Ukunyuka kwesisindo ngequbuliso | Ukunyuka kobunzima bomzimba obuyikhilogram enye okanye ngaphezulu kwixesha elifutshane, njengeeyure ezingama-48. |
| Intlungu | Intlungu okanye ukurhawuzelela esiswini okanye ezantsi kwesisu. |
Ukongeza, ugqirha wakho unokubona izinto ezifana namanqanaba aphezulu e-creatinine kunye namanqanaba e-urea nitrogen egazini kwiingxelo zakho zovavanyo lwegazi nomchamo.
Ukuba ufumana naziphi na kwezi mpawu, qhagamshelana nogqirha wezintso ngokukhawuleza. Uninzi lwezi zifo luvela kwiinyanga ezintathu zokuqala emva kokufakelwa izintso.Ngoko ke kufuneka unakekele umzimba wakho kakuhle ngeli xesha.
Zithini iingozi zempilo ezibangelwa lolu sulelo?
Umngcipheko ophambili we-BK virus nephritis kukonakala kwezintso zakho ezintsha. Kwezinye iimeko ezinzima, umngcipheko wokulahleka ngokupheleleyo kwe-graft ungafikelela kwi-30% ukuya kwi-80%.
Ngaphandle kokonakalisa izintso, le ntsholongwane inokubangela nezinye iingxaki zempilo ezinzulu.
- Umhlaza: Le ntsholongwane inokubangela ukuba iiseli zikhule ngendlela engaqhelekanga kwaye zenze amathumba anomhlaza kwizitho zomzimba.
- I-Capillary leak syndrome: Imeko embi kakhulu ebangelwa kukuvuza kweplasma yegazi esuka kwimithambo yegazi emincinci kakhulu iye kwimisipha ejikelezileyo, amalungu omzimba, kunye nezicubu.
- I-Encephalitis: Ukuba intsholongwane isasazeka iye engqondweni, izicwili zobuchopho zinokudumba. Oku kunokubangela iimpawu ezifana nokutshintsha kobuntu kunye nokuxhuzula.
- I-Pneumonia: Le ntsholongwane isasazeka iye emiphungeni kwaye ibangela ubunzima bokuphefumla ngenxa yolwelo oluyizalisayo.
- I-hepatitis ebangelwa yintsholongwane: Ukusasazeka kwentsholongwane esibindini kunokubangela ukudumba kwesibindi.
Indlela yokuxilonga ngokuchanekileyo esi sifo?
Ugqirha wakho uza kwenza uvavanyo oluninzi ukuqinisekisa ukuba unaso na esi sifo.
| Uvavanyo | Ujonga ntoni? |
|---|---|
| Uvavanyo lwegazi | Bajonga igazi ukuze babone ukuba kukho iziqwenga ze-DNA okanye ze-mRNA zentsholongwane ye-BK. |
| Uvavanyo lomchamo | Umchamo uvavanywa uhlobo oluthile lweseli olubizwa ngokuba "ziiseli ze-decoy." Ezi ziiseli ezenziwe kwiiseli zezintso ezineentsholongwane kwaye zikhutshwa emchameni. Zikwavavanya ukuba kukho iziqwenga ze-DNA/mRNA zentsholongwane. |
| i-biopsy yezintso | Le yeyona ndlela ithembekileyo yokuxilonga isifo. Kuthathwa iziqwenga ezimbini ezincinci kakhulu zezicubu ezintsoni zize zihlolwe. |
Ungazinyanga kwaye uzikhusele njani?
Akukho nyango lunye, oluvunyiweyo ngokuqinisekileyo lwale meko. Nangona kunjalo, ugqirha wakho uza kusebenzisa iindlela ezahlukeneyo ukulawula le meko.
- Ukunciphisa umthamo wee-immunosuppressants: Olu lolona nyango luphambili. Ukuba intsholongwane iqinisekisiwe ukuba iyasebenza, ugqirha wakho uya kugqiba ekubeni anciphise umthamo wamayeza akho.
- Amayeza okulwa neentsholongwane: Amanye amayeza anokunikwa ukunciphisa inani leentsholongwane emzimbeni.
- Amanye amayeza: Kusenokufuneka utshintshe amayeza akho okunciphisa amasosha omzimba okanye unikwe amayeza okubulala iintsholongwane kwiintsholongwane zesibini.
Singazikhusela njani koku?
Ekubeni sonke sifumana le ntsholongwane ebuntwaneni, asinakuyilawula indlela engene ngayo emzimbeni. Nangona kunjalo, kukho izinto ezininzi onokuzenza ukunciphisa umngcipheko wokufumana le meko emva kokufakelwa izintso. Eyona nto ibalulekileyo kukuhlolwa rhoqo njengoko ugqirha wakho ekucebisa.
- Uvavanyo lwegazi nomchamo rhoqo, ngaphambi kokuba kuvele iimpawu, ukujonga ukuba intsholongwane sele iqalile na ukusebenza.
- Ngokwesiqhelo, kucetyiswa ukuba uhlolwe rhoqo emva kweenyanga ezi-3 kwiminyaka emibini yokuqala emva kokufakelwa, uze emva koko uhlolwe minyaka le kangangeminyaka emihlanu.
- Ukuba ezi mvavanyo zifumanisa intsholongwane, ugqirha uya kulungisa umthamo wamayeza okunciphisa umzimba.
Okufuneka ukwenze kukuqwalasela naziphi na iimpawu ezincinci , uzixele kugqirha wakho ngoko nangoko, kwaye wenze uvavanyo alucebisayo ngexesha. Ukuba wenza loo nto, uya kukhuselwa kolu sulelo lunzima kwaye uya kukwazi ukuhlala usempilweni kunye nezintso zakho ezintsha ixesha elide.
Umyalezo Wokuya Ekhaya
- Intsholongwane ye-BK yintsholongwane eqhelekileyo kakhulu engenabungozi kubantu abaphilileyo, kodwa inokuba yingozi kumntu oye wafakelwa izintso.
- Emva kokufakelwa izintso, intsholongwane ebilele emzimbeni isenokuphinda ivuke ngenxa yezixhobo zokunciphisa amajoni omzimba.
- Lumka ngeempawu ezifana notshintsho kumchamo, iintlungu xa uchama, kunye nokunyuka kobunzima ngequbuliso.
- Eyona ndlela ilungileyo yokuzikhusela kule meko kukuhlolwa rhoqo njengoko ugqirha wakho ekucebisile.
- Ukuba unamathandabuzo okanye iimpawu, musa ukulibazisa kwaye udibane nogqirha wakho ukuze akunike icebiso.
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