Xa kufikwa kwisifo seswekile , akukho mntu ungasaziyo kwilizwe lethu. Abantu abaninzi bacinga ukuba kukho iintlobo ezimbini kuphela zesifo seswekile , ezizezi Uhlobo 1 kunye no Uhlobo 2. Kodwa ubusazi na ukuba kukho olunye uhlobo olukhethekileyo lwesifo seswekile ngaphandle kwale? Yiloo nto siyibiza ngokwezonyango ngokuba yiMODY, okanye ' isifo seswekile sokukhula kolutsha'. Esi sisifo esingaqhelekanga, kwaye sifunyanwa njengelifa ngokuthe ngqo. Kubaluleke kakhulu ukuchonga oku ngokuchanekileyo, kuba unyango lwaso lunokwahluka kwezinye iintlobo zesifo seswekile.
Kutheni iMODY iphuhla? Yintoni unobangela?
Ngamafutshane, iMODY ibangelwa lutshintsho, okanye utshintsho, kwijini enye emzimbeni wethu. Lo ngumahluko ophambili phakathi kweMODY kunye nesifo seswekile sohlobo 1 kunye nohlobo 2. Ezinye iintlobo zesifo seswekile zibangelwa zizinto ezidibeneyo, ezifana nejini ezininzi, ukutyeba kakhulu , kunye nendlela yokuphila engafanelekanga. Kodwa iMODY ibangelwa yijini enye.
Khawucinge nje, ngenxa yolu tshintsho lwemfuza, i-pancreas yakho ayivelisi ngokwaneleyo i-hormone ebizwa ngokuba yi-insulin . Njengoko usazi, i-insulin yi-hormone ebalulekileyo enceda umzimba ukuba ufunxe iswekile ekutyeni esikutyayo njengamandla, kwaye ikwalawula amanqanaba eswekile egazini. Ngoko ke xa kungekho insulin yaneleyo, amanqanaba eswekile egazini ayenyuka.
Ngubani onokuba nethuba elikhulu lokufumana le meko?
I-MODY sisifo esizuzwe njengelifa . Oku kuthetha ukuba ukuba umntu kusapho lwakho une-MODY, unokuba nethuba elingcono lokufumana esi sifo. Umzekelo, ukuba umama okanye utata wakho une-MODY, unethuba elingama-50% lokufumana esi sifo. Eli likhonkco elinamandla kakhulu lelifa. Kwezinye iintsapho, esi sifo sinokubonwa kuzo zonke izizukulwana ezintathu: ootatomkhulu noomakhulu, oomama, ootata, nabantwana.
Esi sifo sidla ngokufunyanwa kubantu abancinci abangaphantsi kweminyaka engama-35 ubudala. Nangona kunjalo, sinokuvela nakweyiphi na iminyaka.
Into ebalulekileyo kukuba, ngokungafaniyo nesifo seswekile sohlobo lwesibini, abantu abanesifo se-MODY badla ngokungatyebi kakhulu, kwaye abanalo uxinzelelo lwegazi oluphezulu. Banokuba nobunzima obusempilweni.
Uyazi njani ukuba une-MODY? Zithini iimpawu zayo?
Iimpawu zeMODY zixhomekeke ekubeni unesiphi isiphene kwijini. Ngamanye amaxesha usenokungabi nazo iimpawu konke konke. Kodwa ngokubanzi, esi sifo sikhula kancinci. Usenokuba ubunezinga eliphezulu leswekile egazini kangangeminyaka, kwaye ezi mpawu zinokuvela kamva:
- Unxano oluhlala lukhona kunye nendlala
- Ukufuna ukuchama rhoqo kunesiqhelo
- Umbono ofipheleyo
- Ukuvela rhoqo kwezifo zolusu okanye izifo zemvubelo
- Ukunciphisa umzimba ngaphandle kwesizathu esithile
- Ukudinwa rhoqo
Zeziphi iingxaki ezinokwenzeka ukuba azinyangwa?
Njengezinye iintlobo zesifo seswekile, iMODY ibonakaliswa ngamanqanaba aphezulu eswekile egazini. Ukuba ayinyangwa, amanqanaba aphezulu eswekile egazini ixesha elide anokubangela iingxaki ezinkulu. Oku kuqhelekile nakwiMODY.
- Umonakalo wemithambo-luvo
- Isifo sentliziyo
- Ukonakala kwamehlo (okunokukhokelela ekubeni yimfama ekugqibeleni)
- Iingxaki zeenyawo
- Usulelo oluqhelekileyo lolusu
Ifunyaniswa njani iMODY?
Ngenxa yokuba iimpawu zeMODY zincinci kakhulu, wena okanye ugqirha wakho usenokungacingi ukuba yiMODY ekuqaleni. Xa uvavanyo lwegazi oluqhelekileyo lubonisa ukuba amanqanaba eswekile egazini lakho aphezulu, ugqirha wakho uya kukuxelela ukuba unesifo seswekile. Inyathelo elilandelayo kukufumanisa ukuba loluphi uhlobo lwesifo seswekile onaso.
Ugqirha wakho uza kujonga ngokweenkcukacha imbali yentsapho yakho yesifo seswekile kwaye angayalela uvavanyo lwegazi olukhethekileyo ukuze aqinisekise ukuba akukho sifo seswekile sohlobo 1 okanye uhlobo 2.
Ngokusekelwe kwezi ziphumo, ugqirha wakho unokucebisa uvavanyo lwezakhi zofuzo ukuqinisekisa ukuba unayo na iMODY. Oku kuquka ukuthatha iDNA kwisampulu yamathe okanye yegazi uze uyivavanye kwilebhu ukuze ubone ukuba kukho naluphi na utshintsho kwiizakhi zofuzo ezibangela iMODY.
Iphathwa njani iMODY?
Unyango lweMODY luxhomekeke ekubeni unesiphi isiphene kwijini. Yingakho kubalulekile ukufumana uxilongo oluchanekileyo. Le theyibhile ingezantsi idwelisa ezinye zeentlobo eziphambili zeMODY kunye nonyango lwazo.
| Uhlobo lweMODY | Unyango |
|---|---|
| I-MODY 1 kunye ne-MODY 4 | IiSulfonylureas zihlala zisetyenziswa njengamayeza eswekile. La mayeza avuselela ipancreas ukuba ivelise i-insulin engakumbi. Abanye abantu banokufuna inaliti ye-insulin. |
| I-MODY 2 | Le yimeko ebuthathaka kakhulu. Idla ngokulawulwa ngokutya okunempilo kunye nokuzilolonga . Kwiimeko ezininzi, amayeza awafuneki. |
| I-MODY 3 | Kwinqanaba lokuqala, inokulawulwa ngokutya. Ekuhambeni kwexesha, iipilisi ze-sulfonylureas kunye neenaliti ze-insulin kamva zinokufuneka. |
| I-MODY 5 | Oku kufuna inaliti ye-insulin . Olu luhlobo olungaqhelekanga. Lunokuchaphazela nezinye izitho zomzimba, ezifana nezintso. Ke ngoko, iingxaki ezifana ne-kidney cysts okanye ukungasebenzi kakuhle kwezintso nazo kufuneka zinyangwe. |
| I-MODY 6 | Olu hlobo ludla ngokubonakala xa uneminyaka engama-40 ubudala. I-insulin inikwa njengonyango. |
Njengoko ubona, unyango luyahluka ngokuxhomekeke kuhlobo lweMODY. Ngoko ke, ukuba wena okanye ilungu losapho linesifo seswekile, ingakumbi ukuba saqala sisebancinci kwaye singatyebanga, kubaluleke kakhulu ukuthetha nogqirha wakho ngaso.
Umyalezo Wokuya Ekhaya
- I-MODY luhlobo lwesifo seswekile olwahlukileyo kuhlobo 1 nohlobo 2 kwaye lubangelwa zizizathu zemfuza.
- Oku kudlulela kwizizukulwana ngezizukulwana kwaye kudla ngokuvela kubantu abancinci, abangatyebanga kakhulu.
- Ngenxa yokuba iindlela zonyango zahlukile ngokuxhomekeke kuhlobo lweMODY, kubaluleke kakhulu ukufumana uxilongo oluchanekileyo.
- Ukuba isifo seswekile sifumaneka kwizizukulwana ezininzi zosapho lwakho, qiniseka ukuba uthetha nogqirha wakho ngaso.
- Nokuba loluphi uhlobo lwesifo seswekile, kubalulekile ukulandela icebiso lezonyango ngokuchanekileyo ukuze uphephe iingxaki.
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