Uke wezwa ngale phrotheni engavamile egazini lakho? (Cryoglobulinemia) Ake sixoxe ngayo!

Ngezinye izikhathi izinto ziyenzeka emizimbeni yethu esingazilindele, akunjalo? Namuhla sizokhuluma ngesimo esingajwayelekile kancane, kodwa okufanele kakhulu ukusazi. Lokhu kubizwa ngokuthi i-cryoglobulinemia. Igama lingase lizwakale liyinkimbinkimbi kancane, kodwa ungakhathazeki, ake silichaze kalula.

Kuyini i-cryoglobulinemia? Kalula nje...

Kalula nje, i-cryoglobulinemia yisimo lapho amaprotheni athile angajwayelekile egazini lakho, abizwa ngokuthi ama-cryoglobulin, eqina, ahlangane ndawonye, ​​bese enza amahlule lapho evezwa emazingeni okushisa abandayo. Cabanga ngakho njengowoyela kakhukhunathi oqandisayo uma uwufaka emanzini abandayo. Kodwa lokhu kwenzeka ngaphakathi kwegazi lethu. Lesi simo empeleni siwuhlobo lwe-vasculitis. Kungukuvuvukala, njengokuvuvukala, kwemithambo yegazi yakho, amapayipi amancane athwala igazi emzimbeni wakho wonke. Lapho le mithambo yegazi ivuvukala, ukugeleza kwegazi kungaphazamiseka. Kwenzekani-ke? Isikhumba sakho, imizwa, amalunga, imisipha, futhi okubaluleke kakhulu, izitho zangaphakathi njengezinso zakho, zingalimala. Lokhu ngezinye izikhathi kubizwa ngokuthi i-cryoglobulinemic vasculitis.

Ingabe zikhona izinhlobo ze-cryoglobulinemia?

Yebo, la maprotheni abizwa ngokuthi ama-cryoglobulin nawo awuhlobo lwe-antibody. Kuye ngohlobo lwe-antibody ekhiqizwa umzimba wethu, i-cryoglobulinemia ingahlukaniswa ngezinhlobo ezintathu eziyinhloko:

• Uhlobo I lwe-Cryoglobulinemia: Lokhu kuvame ukubangelwa umdlavuza ohlobene negazi lakho noma umdlavuza ohlobene nesistimu yakho yomzimba.
• I-Cryoglobulinemia yohlobo lwesibili kanye ne-Cryoglobulinemia yohlobo lwesithathu: Lezi zinhlobo ezimbili zivame ukubonakala ngezimo zokuvuvukala ezingamahlalakhona (okungukuthi, zesikhathi eside). Isibonelo, zingabonakala kubantu abanezifo zokuzivikela komzimba . Ikakhulukazi, i-Cryoglobulinemia yohlobo lwesibili ivame kakhulu kubantu abangenwe yigciwane le-Hepatitis C (HCV). Lezi zinhlobo ezimbili zihlanganisiwe futhi zibizwa ngokuthi i-Mixed Cryoglobulinemia.

Sivame kangakanani lesi simo?

I-Cryoglobulinemia empeleni iyisimo esingavamile kakhulu.Kodwa abacwaningi abakakwazi ukusho ngqo ukuthi bangaki abantu abanalesi simo. Ngenxa yokuthi abanye abantu bangase babe namazinga aphansi ala ma-cryoglobulin egazini labo kodwa bangakhombisi zimpawu, abacwaningi balinganisela ukuthi lesi simo sithinta cishe umuntu oyedwa kwabayisigidi emhlabeni jikelele.

Ziyini izimpawu? Ingabe wonke umuntu uthola izimpawu?

Cha, akubona bonke abantu abane-cryoglobulinemia abazoba nezimpawu. Abanye abantu bangase bangaboni lutho. Kodwa uma izimpawu zivela, uphawu oluvame kakhulu ukuqubuka kwesikhumba okubizwa ngokuthi i-purpura. Lokhu kubonakala njengamabala abomvu noma imivimbo ensomi emilenzeni engezansi. Ungase uzizwe ukhathele futhi ube nobuhlungu emalungeni. Ezinye izimpawu zingase zivele. Lezi zifaka:

• Uma ibekwe emazingeni okushisa abandayo, imithambo yegazi ezandleni kanye/noma ezinyaweni iyancipha, okwenza iphenduke ibe luhlaza okwesibhakabhaka. Lokhu kubizwa ngokuthi yi -Raynaud's phenomenon .
• Ukwehlisa isisindo .
• Umfutho wegazi ophezulu (i-Hypertension).
• Ukuvuvukala, ikakhulukazi emaqakaleni nasemilenzeni (i-Edema).
• Izilonda zesikhumba futhi ngezinye izikhathi ukufa kwezicubu (i-gangrene).
• Isibindi esikhulu (i-Hepatomegaly) noma i-spleen ekhulisiwe (i-Splenomegaly).
• Ukuba ndikindiki , ukuqaqamba, noma ubuthakathaka ezithweni.
• Ukulimala kwezinso.

Cabanga ngakho, lokhu akuyona nje indaba yokuthi izitho zakho zomzimba ziphenduka zibe luhlaza okwesibhakabhaka ngenxa yokubanda. Lokhu kungaba uphawu lwenkinga enkulu emzimbeni wakho. Yingakho kubalulekile ukuqaphela izinto ezinjengalezi.

Ziyini izimbangela ze-cryoglobulinemia?

Abacwaningi abakakazi kahle ukuthi yini ebangela i-cryoglobulinemia. Kodwa njengoba sixoxile ngaphambili, uhlobo lwesifo sokuzivikela komzimba esibizwa ngokuthi i-vasculitis, okuwukuvuvukala kwemithambo yegazi. Isifo sokuzivikela komzimba simane nje lapho isimiso somzimba wakho sokuzivikela, uhlelo lokuzivikela lomzimba olukuvikela ezifweni, luhlasela ngephutha izicubu zakho ezinempilo. Kunezici eziningana ezingaba nomthelela kulokhu kusabela:

• Izakhi zofuzo: Uma othile emndenini enayo, ingathinteka.
• Ezinye izinhlobo zemithi: Akuyona yonke imithi, kodwa eminye.
• Izifo namagciwane: Ikakhulukazi izifo ezibangelwa amagciwane.
• Izici zemvelo: Ezinye izinto ezisendaweni esizungezile.

I-Cryoglobulinemia ngezinye izikhathi ingenzeka yodwa ngaphandle kwesizathu esisobala (lokhu kubizwa ngokuthi i-idiopathic), kodwa kaningi kwenzeka uma kuhambisana nezinye izifo. Ezinye zalezi zifo zifaka:

• Ukutheleleka kwe-Hepatitis C: Lokhu kuyisixhumanisi esiyinhloko nesivame ukubonakala.
• Ukukhubazeka kwamangqamuzana egazi: Isibonelo, izimo zomdlavuza ezifana ne-lymphoma kanye ne-multiple myeloma.
• Izifo zezicubu ezixhumeneyo: Isibonelo yi-lupus.

Ubani osengozini enkulu yalokhu?

Kubonakala sengathi i-cryoglobulinemia ithinta abesifazane kakhulu kunabesilisa, futhi ivame kakhulu kubantu abaneminyaka engaphezu kwengu-50.

Ingabe izinkinga zingaba khona uma zingelashwanga kahle?

Yebo, impela. Uma i-cryoglobulinemia ingelashwa kahle, ingabangela umonakalo ohlala njalo esikhumbeni sakho, ezicutshini, nasezithweni zangaphakathi. Ezinye zezinkinga ezinkulu ezingaba khona zifaka:

• Izifo zesikhumba noma amanxeba angapholi.
• Ukufa kwesikhumba (i-necrosis).
• Ukwehluleka kwezinso.
• Ukwehluleka kwesibindi.

Lezi yizimo ezibucayi ngempela, yingakho kubalulekile ukuxilonga nokwelapha lesi sifo ngokushesha.

Odokotela bakuthola kanjani lokhu?

Uma ubona udokotela, uzoqala ngokubuza ngomlando wakho wezokwelapha bese enza ukuhlolwa ngokomzimba. Ngemuva kwalokho, bazo-oda ukuhlolwa kwegazi okukhethekile ukuhlola ama-cryoglobulin egazini lakho. Lokhu kuhlolwa kwegazi kungakutshela nokuthi hlobo luni lwe-cryoglobulin onalo. Lokhu ngezinye izikhathi kungasiza ekutholeni imbangela yesimo sakho nokuthi ungasiphatha kanjani. Ngaphezu kwalokhu kuhlolwa kwegazi, udokotela wakho angase a-oda ezinye izivivinyo eziningana ukuqinisekisa ukuxilongwa nokuqonda isimo:

• Ukuhlolwa komchamo (Ukuhlolwa komchamo).
• I-X-ray yesifuba.
• Ukuskena kwe-CT (i-computed tomography (CT) scan).
• I-angiogram (ibheka isimo semithambo yegazi).
• Ukuhlolwa kwe-MRA (magnetic resonance angiogram) noma i-CT angiogram (CT angiogram).
• Ukuhlolwa kokuqhuba kwemizwa.
• Ukuhlolwa kwe-electromyography (EMG) (bheka ukusebenza kwemisipha).
• I-biopsy (ukuthatha ingxenye encane yezicubu, mhlawumbe esikhumbeni noma ezinso, ukuze ihlolwe).

Kuphathwa kanjani lokhu?

Ukwelashwa kwe-cryoglobulinemia kuncike ekutheni yiziphi izitho zomzimba ezithintekile, ubukhulu bomonakalo, nokuthi unezinye izimo zezokwelapha.Kubalulekile ukwelapha ezinye izimo ezingase zihlotshaniswe ne-cryoglobulinemia, njenge-hepatitis C, kanye nezinye izimo ezingase zihlotshaniswe nayo. Lokhu kungenxa yokuthi ukwelapha lezo ezinye izimo ngezinye izikhathi kungasiza ekunciphiseni izimpawu ze-cryoglobulinemia. Uma izimpawu zakho zingezimbi kakhulu, udokotela wakho angancoma imithi yokunciphisa ubuhlungu ethengiswa ngaphandle kwemithi kadokotela (njenge-NSAID) futhi akucebise ukuthi ugweme ukuchayeka emazingeni okushisa abandayo . Bangase futhi bancome ukuthi uhlolwe njalo ukuze uqaphe isimo sakho. Ezimweni ezithambile, noma eziphakathi kuya kwezinzima, ukwelashwa kungase kuhluke kancane:

• Imithi yokucindezela amasosha omzimba: Lena yindlela yokwelapha eyinhloko. Ama-corticosteroids, njenge-prednisone, ngezinye izikhathi anikezwa kanye neminye imithi. Lokhu kuncike esithweni esithintekile kanye nobukhulu bomonakalo.
• Imithi yokulwa namagciwane: Uma udokotela wakho ethola ukuthi unesinye isimo, njenge-hepatitis C, angase akuncomele ukwelashwa ngamagciwane. Bangase bakuthumele kuchwepheshe wesibindi (i-hepatologist).
• I-Biologics: I-Rituximab iyindlela yokwelapha evamile ye-cryoglobulinemia. I-Biologics amaprotheni ayinkimbinkimbi enziwe ngezinto eziphilayo ahlose izingxenye ezithile zesistimu yomzimba ukuze alawule ukuvuvukala.
• I-Plasmapheresis: Lena enye indlela yokwelapha. Isebenza ngokunciphisa inani lama-cryoglobulin egazini lakho. Kule nqubo, ama-cryoglobulin asuswa ku-plasma yakho (ingxenye ewuketshezi yegazi lakho). Lokhu kusiza ukuvimbela ama-cryoglobulin ukuthi angavali imithambo yakho, avimbele ukugeleza kwegazi futhi anciphise ukulimala kwezitho zomzimba.

Masiqaphele nemiphumela emibi kanye nezinkinga zokwelashwa.

Imithi enikezwa odokotela yokwelapha i-cryoglobulinemia ingaba nemiphumela emibi kakhulu. Emikhulu yi-osteoporosis kanye nokwehla kwamandla omzimba okulwa nezifo. Ngakho-ke, kubaluleke kakhulu ukubona udokotela wakho njalo ukuze ayohlolwa. Ngemuva kwalokho, udokotela wakho angakunikeza eminye imithi yokulawula le miphumela emibi. Kubalulekile futhi ukuzivikela ezifweni. Ngakho-ke, khuluma nodokotela wakho ngemigomo enganciphisa ingozi yokutheleleka.

Ingabe ikhona indlela yokuvimbela lesi simo?

Ngenxa yokuthi imbangela eqondile ye-cryoglobulinemia ayaziwa, ayikho indlela eqondile yokuyivimbela. Kodwa-ke, ukugwema ukuchayeka emakhazeni kungasiza .Kungasiza ekulawuleni ezinye izimpawu, njengesifo sikaRaynaud. Kubaluleke kakhulu futhi ukuthi uhlolwe igciwane le-Hepatitis C bese uthola ukwelashwa uma unalo.

Iyini inkomba yokuthi umuntu ophila nalesi sifo uzogula?

Umbono wakho, okungukuthi, ukuthi lesi sifo sizobukeka kanjani, uncike ezintweni eziningana:

• Ezinye izimo zezokwelapha eziyisisekelo onazo.
• Ubukhulu bomonakalo ezithweni zakho zomzimba.
• Indlela osabela kahle ngayo ekwelashweni.

Futhi, ubukhali besifo buyahlukahluka kuye ngomuntu nomuntu. Abanye abantu bangase bangabi nazimpawu nhlobo, noma isimo sabo singase sibe sincane kangangokuthi abadingi ukwelashwa. Kubantu abanezimo eziphakathi noma ezinzima, ukuxilongwa nokwelashwa kusenesikhathi kungasiza ekunciphiseni izimpawu futhi kuvimbele izinkinga zesikhathi eside. Uma izitho zakho zomzimba zingalimala unomphela, isimo siba sihle kakhulu.

Ngingazinakekela kanjani? Ngubani okhona ukungisiza?

Into engcono kakhulu ongayenza ukusebenzisana eduze nethimba lakho lezokwelapha. Kuye ngokuthi yiziphi izitho zomzimba ezithintekile yi-cryoglobulinemia yakho, kungadingeka ukuthi usebenzisane nethimba lodokotela elihlanganisa imikhakha eminingi. Lokhu kungafaka:

• Odokotela abangochwepheshe ezifweni zamalunga kanye nezicubu ezixhumeneyo (Rheumatologists).
• Odokotela besikhumba.
• Odokotela begazi.
• Odokotela abangochwepheshe bezifo zezinso (odokotela bezifo zezinso).
• Odokotela benhliziyo.
• Odokotela bezinzwa.
• Odokotela bezifo zesibindi.

Yazi kahle ithimba lakho lezokwelapha. Khuluma ngokwakho. Buza imibuzo. Uma unemibuzo mayelana nohlelo lwakho lokwelashwa, khuluma ngalo. Odokotela bakho bakhona ukukulalela futhi baqinisekise ukuthi uqonda ngokugcwele konke okuthinta impilo yakho nokunakekelwa kwakho.

Kufanele ngimbone nini udokotela?

Uma unezimpawu ze-cryoglobulinemia, kufanele ufune usizo lwezokwelapha ngokushesha. Futhi, uma une-hepatitis C futhi kuvela noma yiziphi zalezi zimpawu, bona udokotela. Ngisho noma unezokwelapha okuphumelelayo, lesi sifo singaphinde sibuye (siphinde sibuye). Uma uba nezimpawu ezintsha, uma izimpawu zakho ezikhona ziba zimbi kakhulu, noma uma izimpawu zakho zibuya, bona udokotela. Ukuhlolwa njalo kwezokwelapha kanye nokulandelela njalo kubalulekile ukuthola noma yikuphi ukuphinda kuvele kusenesikhathi nokuvimbela izinkinga.

Yimiphi imibuzo okufanele ngiyibuze udokotela?

Uma ubona udokotela wakho, kuwumqondo omuhle ukubuza imibuzo efana nale:

• Yini eyabangela ukuba ngibe nalesi sifo?
• Yikuphi ukwelashwa okuncomayo?
• Yimiphi imiphumela emibi yokwelashwa okufanele ngikhathazeke ngayo?
• Yiziphi izinkinga ezingaba khona ngenxa yalesi simo?
• Yini engingayenza ukuze ngivimbele lesi sifo ukuthi singaphinde sibuye?

Izinto ezibaluleke kakhulu okudingeka sizikhumbule (Umyalezo Wokuya Ekhaya)

Ukuphila ne-cryoglobulinemia kungaba nzima ngezinye izikhathi. Izimpawu nemiphumela emibi yemithi kungaba nomthelela omkhulu enhlalakahleni yakho yengqondo. Kungathinta nezinye izici eziningi zempilo yakho.

Kodwa khumbula, awuwedwa. Cela usizo kudokotela wakho, futhi uthole amaqembu okusekelana lapho abanye ababhekene nezimo ezifanayo bengahlangana khona. Ukwabelana ngolwazi lwakho nalokho okwaziyo kungakusiza ukuthi uphile ne-cryoglobulinemia. Ukuzivikela emakhazeni, ukufuna iseluleko sezokwelapha, ukungabhemi, nokudla ukudla okulinganiselayo konke kubalulekile.

Ngiyethemba ukuthi lolu lwazi luwusizo kuwe. Hlala uphilile!