Ingabe ubona izinguquko emzimbeni wengane yakho kusenesikhathi? Ake sixoxe nge-Adrenarche!

Usuqalile yini ukubona izinguquko emzimbeni wengane yakho, mhlawumbe ngisho nangaphambi kwesikhathi obusicabanga? Ingabe ngezinye izikhathi kuzwakala sengathi uboya obuncane bukhula emakhwapheni noma ezithweni zangasese, noma kuzwakala sengathi kunephunga elijulukayo? Kuvamile ukuthi umama noma ubaba azizwe esaba futhi ekhathazekile kancane uma ebona lezi zinto. Ngakho-ke namuhla, ake sixoxe ngenqubo yemvelo ebizwa ngokuthi i-adrenarche, okungenzeka ukuthi iyimbangela yalokhu.

Uyazi ukuthi yini i-Adrenarche?

Kalula nje, i-Adrenarche inqubo yemvelo lapho izindlala ze-adrenal zengane yakho ziqala ukukhiqiza i-hormone ebizwa ngokuthi i-DHEA (Dehydroepiandrosterone). Lokhu kuvame ukuqala phakathi kweminyaka engu-6 no-8. Uma sikhuluma iqiniso, lokhu kwenzeka cishe eminyakeni emibili ngaphambi kokuba ingane iqale ukukhombisa izimpawu zokuthomba (pubarche).

Cabanga ngale hormone i-DHEA njengento eluhlaza. Umzimba wethu uyisebenzisela ukwenza amanye ama-hormone abalulekile. Isibonelo, ama-hormone eqenjini le-androgen (njenge-testosterone ne-androstenedione) kanye ne-hormone i-estrogen nawo enziwa ngale DHEA. Lawa ma-hormone e-androgen asiza ekuqaliseni ukuthomba, futhi abalulekile empilweni yokuzala kanye nokukhula komzimba.

Olunye uhlobo lwe-DHEA lubizwa ngokuthi i-DHEAS (Dehydroepiandrosterone-sulfate). Lolu uhlobo lwe-DHEA olujikeleza egazini lethu. Ukuhlolwa kwegazi kungalinganisa izinga le-DHEAS ukuze kutholakale ukuthi ngabe umsebenzi we-adrenal uyenzeka yini. Kodwa-ke, ngoba lokhu kuyinqubo yemvelo, lokhu kuhlolwa kwegazi akwenziwa njalo ezinganeni.

Kwenzekani ngempela ngesikhathi se-adrenarche?

Ngesikhathi se-adrenarche, ingxenye engaphandle yezindlala ze-adrenal zengane yakho, i-adrenal cortex, iqala ukukhula nokuvuthwa.

Kunezingqimba ezintathu zale cortex ye-adrenal:

• I-Zona glomerulosa (ungqimba olungaphandle)
• I-Zona fasciculata (ungqimba oluphakathi)
• I-Zona reticularis (ungqimba olungaphakathi kakhulu). Le ngxenye, ebizwa ngokuthi i-zona reticularis, iyona ethuthuke kakhulu kumdlavuza we-adrenal.

Njengoba lokhu kukhula, izindlala ze-adrenal zikhiqiza i-DHEA, umzimba oguqula ibe ama-hormone e-androgen. Le DHEA kanye nama-hormone ewakhiqizayo yikona okuqalisa noma okwandisa okulandelayo:

• Izindlala ezinamafutha: Lezi yizindlala esikhumbeni sethu ezikhiqiza uketshezi olunamafutha (i-sebum). Lokhu ketshezi kusiza isikhumba ukugcina umswakama futhi kuhlinzeke ngesembozo esivikelayo. Umsebenzi wazo uthinta nephunga lomzimba.
• Ama-Apocrine glands: Lawa ama-glands akhethekile atholakala ezindaweni ezifana namakhwapha kanye nezimbotshana. Ahlala engasebenzi kuze kube yilapho ekhuthazwa ama-hormone e-adrenal ngesikhathi somjikelezo we-adrenal.
• Izinwele zasesibelethweni nasekhwapheni:Izinwele zase-pubic uhlobo lwezinwele ezimnyama kancane futhi ezijiyile. Kungenxa ye-hormone ye-androgen ukuthi izinwele zase-axillary ziqala ukukhula endaweni yase-pubic nasemakhwapheni.

Okubalulekile, lawa ma-hormone e-adrenal ahlukile kuma-hormone abangela ukukhulisa amabele kanye nezitho zangasese zabesilisa (ezibizwa ngokuthi i-gonadarche) ngesikhathi sokuthomba. I-Gonadarche ukukhiqizwa okwandisiwe kwama-hormone ocansi ayinhloko (i-estrogen noma i-testosterone) ngama-ovari nama-testicles. Lawa malungu nama-hormone ayadingeka ekuzaleni ngokocansi. Ama-hormone e-adrenal awathinteki ngqo.

I-Adrenarche ne-gonadarche kuyizinqubo ezimbili ezihlukene, ezizimele. Abacwaningi abakazi kahle ukuthi yini ebangela i-adrenarche.

I-Adrenarche ihlala isikhathi esingakanani?

I-Adrenarche ivame ukuhlala cishe iminyaka emibili, kuze kube yilapho kuqala i-pubarche, uphawu lokuqala lokuthomba. Kodwa-ke, izindlala ze-adrenal zengane yakho ziyaqhubeka nokukhiqiza i-DHEA kuze kube yilapho isikhulile. Amazinga e-DHEA aphezulu kakhulu kubantu abasebasha (cishe eminyakeni engama-20-24 ubudala), bese ehla kancane kancane njengoba ukhula.

Ziyini izimpawu ze-Adrenarche?

Eqinisweni, azikho izimpawu ezibonakalayo ze-adrenarche. Okusho ukuthi, lapho amazinga e-DHEA eqala ukwanda, akukho shintsho olubonakalayo emzimbeni wengane oluhlobene ngqo nalo.

Kodwa-ke, cishe eminyakeni emibili ngemva kokuqala kokungapheleli kwe-adrenal, izinwele ze-pubarche , noma ze-pubic, ziqala ukuvela. Odokotela babheka lokhu njengomphumela womzimba wokungapheleli kwe-adrenal. I-Pubarche iphawula ukuqala kokuthomba.

Ezinye izici zezinwele zasesithweni sangasese yilezi:

• Ukubonakala kwezinwele ze-axillary.
• Iphunga lokujuluka (iphunga lomzimba / iphunga le-apocrine).
• Ukwanda kwamafutha esikhumba nezinwele zengane.
• Induna.

Izinwele zesitho sangasese zivame ukuqala ukuvela zineminyaka emingaki?

Lokhu empeleni kuyahlukahluka kancane kusuka enganeni kuya enganeni, kuye ngokuthi ingowesilisa noma owesifazane, kanye nangohlanga kanye nobuzwe. Isibonelo, nansi iminyaka ephakathi ngokwezinhlolovo ezenziwe e-United States:

• Kwamantombazane amnyama angewona amaSpanishi, aneminyaka engaba ngu-9.5 ubudala.
• Kumantombazane aseMexico-America, cishe aneminyaka eyi-10.3 ubudala.
• Kwamantombazane amhlophe angewona amaHispanic, aneminyaka engaba ngu-10.5 ubudala.
• Kubafana abamnyama abangewona amaHispanic, cishe baneminyaka engu-11.1 ubudala.
• Kubafana baseMexico-America, cishe baneminyaka eyi-12.3 ubudala.
• Kwabafana abamhlophe abangewona amaHispanic, abaneminyaka ecishe ibe yi-12.

Into ebalulekile ukuthi akuzona zonke izingane ezifanayo, umzimba womuntu wonke ukhula ngendlela yawo ehlukile. Lezi zigaba zeminyaka zingase zifane cishe ezinganeni zaseSri Lanka, kodwa kunomehluko phakathi kwengane nengane.Uma unemibuzo noma ukukhathazeka mayelana nokukhula kwengane yakho, into engcono kakhulu ongayenza ukukhuluma nodokotela wezingane.

Kuyini i-Adrenarche Yangaphambi Kwesikhathi?

I-adrenarche yangaphambi kwesikhathi yilapho izinto ezifana nezinwele zasesithweni sangasese kanye nezingalo kanye nephunga lomzimba ziqala ngaphambi kwesikhathi kunokulindelekile. Ngokuvamile, lezi zimpawu zivela ngaphambi kweminyaka engu-8 emantombazaneni nangaphambi kweminyaka engu-9 kubafana. Lokhu kungaba i-adrenarche yangaphambi kwesikhathi.

Lokhu empeleni kubizwa ngokuthi i-premature pubarche, ngoba asinayo indlela yokwazi ukuthi inqubo yangaphakathi ebizwa ngokuthi i-adrenarche iqale kusenesikhathi, kuze kube yilapho kuvela uphawu lwayo olubonakalayo, i-pubarche.

Ucwaningo lubonisa ukuthi amantombazane anamathuba aphindwe kasishiyagalolunye okuthola lesi simo kunabafana. Isizathu esiqondile salokhu asikaziwa okwamanje.

Ziyini izimpawu ze-adrenarche ngaphambi kwesikhathi?

Izimpawu eziyinhloko zokungakwazi ukusebenza kahle kwe-adrenal yilezi:

• Izinwele zivela endaweni yesitho sangasese kanye/noma emakhwapheni ngaphambi kweminyaka engu-8 yentombazane, noma ngaphambi kweminyaka engu-9 yentombazane.
• Iphunga lomzimba elivela emakhwapheni lingabangela isidingo sokusebenzisa into efana ne-deodorant.

Izingane ezinalolu hlobo lokungakwazi ukusebenza kahle kwe-adrenal zivame ukuba zinde kunezinye ezineminyaka yazo, ngezinye izikhathi zize zibe ngaphezu kwe-90th percentile kumashadi okuphakama ngokweminyaka yazo nobulili bazo.

Kodwa nansi into okufanele uyikhumbule: Ukuthomba ngaphambi kwesikhathi akubangeli ukukhula kwebele ngaphambi kwesikhathi noma ukukhula kocansi kwasekuqaleni kubafana (okungukuthi, i-gonadarche). Uma ingane yakho ibonisa lezi zinguquko zebele noma zocansi kusenesikhathi, kanye nokukhula kwezinwele kanye nephunga lomzimba, cishe akuyona ukuthomba ngaphambi kwesikhathi, kodwa kunalokho kuyisimo esibizwa ngokuthi ukuthomba ngaphambi kwesikhathi . Lokho kuyindaba ehlukile.

I-Adrenarche Yangaphambi Kwesikhathi Itholakala Kanjani?

Uma ingane yakho isolwa ukuthi inezimpawu zokungasebenzi kahle kwe-adrenal, udokotela wakho wezingane uzoqala ahlole ukuthi ikhona yini enye imbangela eyisisekelo yalezi zimpawu. Ezinye zalezi zimo zingafaka:

• Ukuthomba kwangaphambi kwesikhathi
• I-Congenital adrenal hyperplasia - Lena inkinga yokuzalwa nokukhiqizwa kwama-hormone athile ezindlaleni ze-adrenal.
• Ukuvezwa kwe-androgen yangaphandle - isibonelo, okuvela ezinhlotsheni ezithile zezimonyo.
• Izimila ezikhipha i-androgen.

Ingane yakho izohlolwa ngokomzimba. Ngalesi sikhathi, udokotela angase afune ukuhlola indawo yokuzala yengane. Uma bekwenza lokho, nakanjani bazothola imvume kuwe nakumntwana wakho (kuye ngokuthi uneminyaka emingaki). Bangase batuse nezinto ezifana nokuhlolwa kwegazi nokuhlolwa kwezithombe.

Ngezinye izikhathi, udokotela wakho wezingane angakuthumela kudokotela we-endocrinologist wezingane, uchwepheshe wama-hormone. Kuphela ngemva kokuba zonke lezi zivivinyo seziqediwe futhi kungekho zimo ezimbi ezishiwo ngenhla ezikhishwe ngaphandle lapho ingane yakho izotholakala ukuthi inokungasebenzi kahle kwe-adrenal.

Kubalulekile ukwazi ukuthi cishe u-90% wamacala ezinwele ze-pubic ngaphambi kwesikhathi ezinganeni abangelwa yilesi simo esibizwa ngokuthi i-adrenal insufficiency. Amanye u-10% abangelwa ezinye izimo zezokwelapha ezishiwo ngenhla.

Ingabe i-Adrenarche Yangaphambi Kwesikhathi Iyingozi?

Njengomzali, kuvamile ukuzizwa ukhathazekile futhi wesaba kancane lapho izinwele zengane yakho emakhwapheni nasezinsikeni zivela ngaphambi kwesikhathi kunokulindelekile, noma lapho ziqala ukunuka njengomjuluko. Kodwa-ke, ukungasebenzi kahle kwe-adrenal cortex ngaphambi kwesikhathi akuyona into eyingozi ngokomzimba.

Kodwa-ke, ucwaningo lukhombisile ukuthi lesi simo singase sandise kancane ingozi yokuthola izinkinga ezithile zempilo esikhathini esizayo. Ezinye zalezi zinkinga zifaka:

• Ukukhuluphala ngokweqile
• Ukumelana ne-insulin - Lokhu kusho ukuthi amangqamuzana omzimba awasabeli kahle ku-insulin, okungaholela ekuthambekeleni kwesifo sikashukela.
• I-Polycystic ovary syndrome (PCOS) - Lesi yisimo samahomoni emantombazaneni esibangela ukwakheka kwama-cyst amancane kuma-ovari.
• Izinkinga zemizwa - okungukuthi, izinguquko zemizwa, njengokudabuka, ukukhathazeka, njll.

Ngaphezu kwalezi zingozi zomzimba, ukuthomba ngaphambi kwesikhathi kungathinta nempilo yengqondo yengane. Cabanga nje, lapho ingane ibhekana nezinguquko zakuqala emzimbeni wayo, ngokungafani nezinye izingane ezingontanga yayo, ingase izizwe inamahloni, ingakhululekile, futhi izizwe ihlukile futhi ingajwayelekile. Ingase futhi ihlekiswe ezinye izingane (ukuxhashazwa) futhi ithole ukunakwa okungafuneki kwabanye. Uma ubona ukuthi ingane yakho izizwa idabukile noma ikhathazekile ngento efana nale, kungumqondo omuhle ukufuna iseluleko kumuntu ofanelekayo, njengodokotela wengqondo wezingane.

Ingabe kukhona ukwelashwa kwe-adrenarche ngaphambi kwesikhathi?

Cha. Uma izinwele seziqala ukukhula endaweni yangasese noma emakhwapheni, okwamanje akukho ukwelashwa okungazivimba noma ukuzikhulisa kabusha.

Nakuba kunemithi ethile engasiza ekulawuleni inqubo yama-hormone esimweni esibizwa ngokuthi ukuthomba ngaphambi kwesikhathi, le mithi ayithinti ama-hormone ahlobene nezindlala ze-adrenal.

Ingabe i-Adrenarche Yangaphambi Kwesikhathi ingavinjelwa?

Lokhu ngokuvamile akuyona into engavinjelwa. Kodwa-ke, ucwaningo luthole ukuthi izici ezithile zingandisa ingozi yengane yokuthola ukungasebenzi kahle kwe-adrenal. Ezinye zalezi zici zifaka:

• Ukuzalwa unesisindo esincane kakhulu (enesisindo esingaphansi kwamakhilogremu angu-2.5, noma amakhilogremu angu-5 nama-ounces angu-8, ngesikhathi sokuzalwa).
• Ukuzalwa ngaphambi kwesikhathi (ukuzalwa ngaphambi kwamasonto angu-37 okukhulelwa).
• Uma kube nomlando wokulimala kobuchopho, lolu hlobo lokulimala kobuchopho luphinde lwandise ingozi yokuthomba ngaphambi kwesikhathi.

Okokugcina, izinto okufanele uzazi

Njengabazali, kuvamile ukuzizwa ukhathazekile futhi ukhungathekile lapho ubona ingane yakho ikhula kancane kancane futhi ifinyelela ekuthombeni, ikakhulukazi uma ubona lezo zinguquko zomzimba kusenesikhathi kunalokho obekulindelwe.

Kodwa-ke, into ebaluleke kakhulu okudingeka uyazi ukuthi i-adrenarche kanye ne-pubarche ehambisana nayo kuyizinqubo zemvelo, ezivamile ezenzeka empilweni yengane ngayinye.

I-adrenarche yangaphambi kwesikhathi ingaba yinto eshaqisayo, kodwa khumbula, ngokuvamile ayibangeli ukulimala okukhulu ngokomzimba enganeni.

Uma unemibuzo noma unemibuzo mayelana nokukhula kwengane yakho noma izinguquko emzimbeni wayo, sicela ungangabazi ukubonisana nodokotela wezingane. Udokotela uzokwazi ukuhlola ingane yakho futhi akuchazele ukuthi ikhula kahle yini futhi njengoba kulindelekile.

I - Adrenarche, i-Adrenarche, i-DHEA, Ukuthomba, i-Pubarche, Ukuthomba Kwangaphambi Kwesikhathi, i-Adrenarche Yangaphambi Kwesikhathi, Impilo Yengane, Ama-hormone, Ukuthuthukiswa Kwengane