Ungase futhi uhlushwa ukucindezeleka kwengqondo okuncane noma ukucindezeleka kulezi zinsuku. Ngaleso sikhathi, udokotela wakho kungenzeka ukuthi ukunike umuthi obizwa ngokuthi i-Vilazodone (owaziwa nangokuthi i-Viibryd). Lona umuthi futhi osetshenziselwa ukwelapha ukucindezeleka. Kodwa uhlukile kancane kweminye imithi. Ngakho-ke namuhla, ake sixoxe ngezinto ezibaluleke kakhulu okudingeka uzazi ngalo muthi we-Vilazodone.
Yiziphi izimo ezelapha i-Vilazodone (Viibryd)?
Lo muthi, obizwa ngokuthi i-Vilazodone, unikezwa ngokuyinhloko njengomuthi wokwelapha i -Major Depression Disorder (MDD) . Yilokhu esivame ukukubiza ngokuthi "ukucindezeleka".
Futhi, ngezinye izikhathi odokotela bangase bakunike lo muthi kwezinye izimo. Isibonelo:
- Izinkinga Zokukhathazeka
- Isifo sokucindezeleka ngemva kokucindezeleka (PTSD)
- Ukucindezeleka Kwe-Bipolar
- Ubuhlungu obungapheli
- Ukushisa okwenzeka ngesikhathi sokunqamuka kokuya esikhathini
Nakuba i-Vilazodone ingavunyelwe ngokusemthethweni ukwelapha lezi zimo, ezinye iziguli ziye zaba nemiphumela emihle ngayo, ngakho odokotela batusa ukuthi "ingavunyelwe," okusho ukuthi ayivunyelwe ngokusemthethweni kulesi simo, ukuze kuzuze isiguli.
Into ebaluleke kakhulu ukuthi lo muthi uvunyelwe abantu abadala kuphela . Awunikezwa izingane. Ngokuvamile, odokotela banikeza lo muthi kubantu abangazange bathole imiphumela ephumelelayo besebenzisa omunye umuthi wokucindezeleka .
Lo muthi usebenza kanjani emzimbeni?
Ukuze siqonde lokhu, sidinga kuqala ukwazi okuncane nge -serotonin ebuchosheni bethu. Kalula nje, i-serotonin iyikhemikhali elawula izinto eziningi ebuchosheni bethu, okuhlanganisa isimo sethu sengqondo, injabulo, kanye nokulala. Kukholelwa ukuthi abantu abanesifo sokucindezeleka banamazinga aphansi ale serotonin.
Okwenza i-Vilazodone ihluke kwezinye ukuthi yandisa amazinga e-serotonin ngezindlela ezimbili.
1. Ukusebenza njenge-SSRI:I-Vilazodone iyisidakamizwa esisesigabeni semithi ebizwa ngokuthi i-Selective Serotonin Reuptake Inhibitors (SSRIs) . Ngemva kokukhishwa kwe-serotonin, ivame ukumuncwa kabusha emangqamuzaneni ezinzwa . Kodwa i-SSRI iyivimbela ukuthi ingamuncwa kabusha. Lokhu kuvumela i-serotonin ukuthi ihlale ebuchosheni isikhathi eside, okusiza ekuthuthukiseni isimo sethu sengqondo.
2. Ukusebenza njenge-5-HT1A Partial Agonist: Lo muthi uphinde uvuselele ama-receptor athola imiyalezo ye-serotonin. Lokhu kwandisa umsebenzi we-serotonin.
Ngenxa yokuthi yandisa amazinga e-serotonin ebuchosheni ngazo zombili izindlela , i-Vilazodone ingase isebenze kangcono kwabanye abantu.
Isetshenziswa kanjani i-Vilazodone (i-Viibryd)?
Lomuthi uza ngesimo sephilisi. Into ebaluleke kakhulu ukuthi leli philisi kufanele liphuzwe njalo kanye nokudla. Liphuze kanye nengilazi yamanzi ngemva kokudla.
Udokotela wakho uvame ukuqala ngo-10mg (ama-milligram) ngosuku. Ngemva kwezinsuku ezingaba ngu-7 zokuwuthatha, bazokwandisa umthamo ube ngu-20mg uma kudingeka. Abanye abantu kungadingeka bandise umthamo ube ngu-40mg. Kodwa-ke, kufanele kube okungenani igebe lezinsuku ezingu-7 phakathi komthamo ngamunye. Konke lokhu kuzokwenzeka ngokwemiyalelo kadokotela wakho.
Kuthatha isikhathi esingakanani ukuthola imiphumela?
Lona umbuzo abantu abaningi abawubuzayo. Ngemva kwesonto noma amabili okuqala umuthi, uzobona ukuthi isifiso sakho sokudla, ukulala, kanye namazinga akho amandla azothuthuka kancane. Lokhu kusho ukuthi umuthi uqala ukusebenza. Kodwa-ke, kungathatha cishe amasonto ayi-6 kuya kwayi-8 ukuthi ukucindezeleka kuphele ngokuphelele nokuthi intshisekelo yakho emsebenzini ibuye. Ngakho-ke sicela ubekezele futhi usebenzise umuthi.
Kubaluleke kakhulu: Lo muthi kufanele usetshenziswe ngokuqapha, njengoba kufanele uwuyeke. Ungalokothi uyeke ukuwuthatha ngokuzumayo ngaphandle kweseluleko sikadokotela wakho. Ukwenza kanjalo kungabangela imiphumela emibi kakhulu (i-discontinuation syndrome) njengesicanucanu, ukuhlanza, ukukhathazeka, ikhanda elibuhlungu, imizwa yokuxhuzula, kanye nokujuluka. Uma uyeka ukuthatha umuthi, kufanele wehlise kancane kancane umthamo. Udokotela wakho uzochaza ukuthi ungakwenza kanjani lokhu.
Iyini imiphumela emibi yalo muthi?
Njengeminye imithi yokucindezeleka, i-Vilazodone ingabangela imiphumela emibi. Eminye ivamile, kodwa eminye ingaba yingozi. Izinto ezifana nokucasuka kanye nokuphazamiseka kwesisu zizophela njengoba umzimba wakho ujwayela imithi. Kodwa kunezimpawu ezithile okufanele utshele udokotela wakho ngazo.
| Uhlobo lomphumela ongemuhle | Izimpawu ezingaba khona |
|---|---|
| Imiphumela Emibi Evamile | |
| Izinkinga zesistimu yokugaya ukudla | Uhudo (ukuqunjelwa), isicanucanu, ukuhlanza. |
| Izinkinga zokulala | Ukungalali kahle noma ukuphazamiseka kokulala. |
| Imiphumela Engavamile Engavamile | |
| Izinkinga zocansi | Ukwehla kwesifiso socansi, ubunzima bokumisa noma ukugcina ukuma, ukuphumula kwesikhashana. (Kodwa-ke, lo muthi unemiphumela emibi embalwa yocansi kuneminye imithi ye-SSRI.) |
| Ukuhlanya/Ukuhlanya | Uma unesifo sokuphazamiseka kwengqondo esibizwa ngokuthi yi-bipolar disorder, ungase ube nezimpawu ezifana nokuzizwa unamandla aphezulu, ukuziphatha okungenangqondo, kanye nokugeleza kwemicabango ngokushesha. |
| Imiphumela Emibi Engathi sína edinga usizo lwezokwelapha ngokushesha | |
| I-Serotonin Syndrome | I-serotonin eningi emzimbeni. Izimpawu zifaka phakathi ukucasuka, ukubona izinto ezingekho, ukujuluka ngokweqile, ukushaya kwenhliziyo okusheshayo, ukuqina kwemisipha, ukuthuthumela, ukuhlanza, kanye nesifo sohudo. Lesi yisimo esiphuthumayo. |
| Imicabango yokuzibulala | Imicabango yokuzibulala noma yokuzilimaza, ikakhulukazi uma uqala ukuthatha umuthi noma lapho umthamo ushintshwa. Uma unale micabango, tshela udokotela wakho noma othile oseduze nawe ngokushesha. |
| Ukuquleka | Ingozi iphezulu uma uke waba nokuxhuzula ngaphambili noma unesifo sokuxhuzula. |
| Ukopha okungavamile | Ingozi iphezulu uma isetshenziswa ngamaphilisi okudambisa izinhlungu njenge-aspirin, ama-NSAID (isib., i-Ibuprofen, i-Diclofenac), noma eminye imithi yokwehlisa igazi. |
| I-Glaucoma Yokuvalwa Kwe-Angle | Ubuhlungu bamehlo, ukubona okufiphele, ukubona amasongo anemibala azungeze izibani. |
| Ukwehla kwe-sodium egazini (i-Hyponatremia) | Ikhanda elibuhlungu, izinkinga zokukhumbula, ukudideka, ukungazinzile lapho uhamba. Ezimweni ezimbi kakhulu, ukulahlekelwa ukwazi kanye nokuxhuzula kungase kwenzeke. |
Izixwayiso okufanele uziqaphele uma usebenzisa i-Vilazodone (i-Viibryd)
Ngaphambi kokuqala lo muthi, qiniseka ukuthi utshela udokotela wakho ngalezi zinto.
- Eminye imithi oyithathayo: Tshela udokotela wakho nganoma yimiphi imithi, amavithamini, noma imithi yamakhambi oyithathayo, ikakhulukazi i-aspirin, ama-NSAID (njenge-ibuprofen), kanye neminye imithi yokwehlisa igazi.
- Ukukhulelwa nokuncelisa: Qiniseka ukuthi utshela udokotela wakho uma ukhulelwe, uhlela ukukhulelwa, noma uncelisa.
- Ezinye izimo zezokwelapha: Sicela usazise uma unesifo sokuphazamiseka kwengqondo, isifo sokuwa noma sokuwa, i-glaucoma, isifo sesibindi noma sezinso.
- Ijusi le-Grapefruit: Tshela udokotela wakho uma uphuza ijusi le-grapefruit njalo, njengoba kungathinta ukusebenza kahle kwalomuthi.
- Imithi ye-MAOI: Kungcono ukungasebenzisi i-Vilazodone uma uthatha enye imithi yokucindezeleka ebizwa ngokuthi i-Monoamine Oxidase Inhibitor (MAOI) noma usanda kuyeka ukuyithatha. Odokotela batusa ukuthi ulinde okungenani izinsuku ezingu-14 ngemva kokuyeka i-MAOI ngaphambi kokuqala lo muthi.
Umlayezo Wokuya Nawe Ekhaya
- I-Vilazodone (i-Viibryd) umuthi owelapha isifo sokucindezeleka okukhulu (i-MDD) futhi wandisa amazinga e-serotonin ebuchosheni ngezindlela ezimbili.
- Lomuthi kufanele uthathwe njalo kanye nokudla .
- Kungathatha cishe amasonto ayi-6-8 ukuzwa imiphumela ephelele yomuthi, ngakho-ke yiba nesineke futhi uqhubeke nokuwusebenzisa.
- Ungayeki ukuthatha imithi ngokuzumayo nganoma yisiphi isizathu ngaphandle kweseluleko sikadokotela wakho.
- Qaphela imiphumela emibi engathi sína njenge-serotonin syndrome, imicabango yokuzibulala, kanye nokuquleka. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, bona udokotela ngokushesha.
- Yazisa udokotela wakho ngayo yonke eminye imithi oyithathayo kanye nanoma yiziphi ezinye izimo zezokwelapha ongase ube nazo ngaphambi kokuqala umuthi.
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