Kujwayelekile ukuthi igazi lijiye futhi liyeke ukuphuma kwegazi uma silimala. Empeleni kuyindlela yokuzivikela yomzimba wethu. Kodwa-ke, uma amajiye egazi akheka emithanjeni yomzimba njalo ngaphandle kwesizathu, kuyindaba yokukhathazeka. Ikakhulukazi uma uqhubeka nokuphuphuma kwesisu ngesikhathi sokukhulelwa, imbangela ingaba yilesi simo esibizwa ngokuthi i-Antiphospholipid Syndrome (APS), esizokhuluma ngaso namuhla.
Kuyini i-APS kalula?
Kalula nje, i-Antiphospholipid Syndrome (APS) yisimo esenza umzimba wakho ube namathuba amaningi okwenza amahlule egazi kunokujwayelekile. Odokotela ngezinye izikhathi bayibiza ngokuthi i-Antiphospholipid antibody syndrome.
Lokhu kuqhekeka kwegazi kungabangela izinkinga ezinkulu, ngisho nezisongela ukuphila, njengokushaywa yisifo sohlangothi . Lesi simo siphinde sandise ingozi yokuphuphuma kwesisu kanye nezinye izinkinga ngesikhathi sokukhulelwa.
I-APS empeleni iyisifo sokuzivikela komzimba . Cabanga nje, sinesimiso sokuzivikela emzimbeni wethu njengebutho. Sisibiza ngokuthi isimiso sokuzivikela komzimba. Umsebenzi waso ukusivikela kumagciwane kanye nezifo ezibangela izifo. Kodwa kulesi sifo sokuzivikela komzimba, okwenzekayo ukuthi isimiso sethu sokuzivikela siqala ngephutha ukuhlasela amangqamuzana amahle emzimbeni wethu.
Ziyini izimpawu zalesi simo?
Abanye abantu abane-APS bangase babe namabala amnyama esikhumbeni sabo abukeka njengenethi. Lokhu kubizwa ngezokwelapha ngokuthi i-livedo reticulitis . Kodwa-ke, iningi labantu abane-APS abanazo izimpawu kuze kube yilapho beba namahlule egazi noma babe nenkinga ngesikhathi sokukhulelwa.
Lezi yizimpawu ezingaba khona uma kwakheka ihlule legazi. Kufanele uqaphele kakhulu ngalezi zimpawu.
| Isibonakaliso | Incazelo |
|---|---|
| Ubuhlungu besifuba | Kungabangelwa ukugoba kwegazi enhliziyweni noma emaphashini. |
| Ubunzima bokuphefumula (ukuphelelwa umoya) | Kungabangelwa, ikakhulukazi, ukugoba kwegazi emaphashini (i-pulmonary embolism). |
| Ubuhlungu bekhanda obuvamile | Kungase kube nenkinga ngemithambo yegazi eholela ebuchosheni. |
| Ubuhlungu obungazelelwe | Ubuhlungu obungazelelwe ezingalweni, emilenzeni, emhlane, entanyeni, noma emhlathini. |
| Ukuvuvukala noma ukubomvu | Kungabangelwa ukuqhekeka kwegazi, ikakhulukazi engalweni noma emlenzeni. |
| Isisu esibuhlungu | Kungabangelwa ukuqhekeka kwegazi emithanjeni yegazi enikeza igazi ezithweni zesisu. |
Okubaluleke kakhulu: Ihlule legazi liyisimo esiphuthumayo esisongela ukuphila. Uma usola ukuthi unehlule legazi, hamba ngokushesha emnyangweni wezimo eziphuthumayo esibhedlela (ETU).
Ngaphezu kwalezi zimpawu, i-APS ingabangela nezinye izimpawu esingenakuzibona noma esingenakuzizwa.
- Ukwehla kwamazinga e-platelet egazini.
- I-anemia.
- Ukukhubazeka kwe-valve yenhliziyo.
Kungani lokhu kwenzeka?
I-Antiphospholipid Syndrome yenzeka lapho amasosha omzimba wakho eqala ngephutha ukwenza uhlobo olungavamile lwe-antibody. Ngokuvamile, ama-antibodies amaprotheni akhethekile afuna futhi abhubhise amagciwane kanye nezinto ezibangela ukungezwani komzimba ezingena emizimbeni yethu. Afana namarobhothi okuzivikela.
Kodwa kumuntu one-APS, la ma-antibodies, enziwa amasosha omzimba, ahlasela amaprotheni anamathele kuma -phospholipid (uhlobo lwamafutha) emaseli ethu. Lokhu kuhlasela kulimaza ama-phospholipid, okwenza kube lula ukuthi anamathele ndawonye futhi akhe amahlule egazi.
Kunezinhlobo ezintathu eziyinhloko zama-antibodies angabangela i-APS:
- I-Lupus anticoagulant
- I-Anticardiolipin
- I-Anti-B2 glycoprotein 1
Umuntu one-APS angaba ne-antibody eyodwa, ezimbili, noma zonke ezintathu. Kodwa okumangazayo nakakhulu ukuthi abanye abantu bangase babe nalezi antibodies kodwa bangalokothi babe nezimpawu ze-APS. Ochwepheshe abasazi kahle ukuthi yini ebangela ukuthi amasosha ethu omzimba enze la masosha omzimba anephutha.
Ubani osengozini enkulu yalesi simo?
Noma ubani angaba ne-APS. Kodwa-ke, ungase ube sengozini enkulu kancane uma:
- Uma ungowesifazane .
- Uma uneminyaka ephakathi kuka -30 no-40 ubudala.
- Uma unezinye izifo ezihlasela amasosha omzimba, njenge-lupus noma i-rheumatoid arthritis.
- Uma omunye wamalungu omndeni wakho aseduze (abazali, ogogo nomkhulu) ene-APS.
Yiziphi izinkinga ezingaba khona ngenxa ye-APS?
I-Antiphospholipid syndrome ingabangela izinkinga ezinkulu, ngezinye izikhathi ezibulalayo. Izinkinga ezinkulu kakhulu zenzeka lapho kwakheka amahlule egazi futhi kuvimbela imithambo yegazi ehlinzeka ngegazi ezithweni ezibalulekile zomzimba wakho.
- Ubuchopho: ukushaywa yisifo sohlangothi
- Inhliziyo: Ukuhlaselwa yinhliziyo (i-thrombosis)
- Amaphaphu: Ukuvaleka kwemithambo yegazi emaphashini (i-pulmonary embolism)
- Izinso: Ukulimala kwezinso
Uma ukhulelwe, ukujiya kwegazi okuvimba ukutholakala kwezakhamzimba ku-placenta kungabangela ukuphuphuma kwesisu. Kuphinde kwandise ingozi ye- preeclampsia, isimo lapho umfutho wegazi ophezulu uvela khona ngesikhathi sokukhulelwa.
I-Catastrophic antiphospholipid syndrome (CAPS) iyinkinga engavamile kodwa engathi sína ye-APS. Yisimo lapho amahlule egazi akheka khona ezithweni eziningi zomzimba esikhathini esiyizinsuku ezimbalwa. Cishe ingxenye yabantu abathola lesi simo bayafa. Kodwa-ke, i-CAPS yenzeka kubantu abangaphansi kwe-1% abane-APS.
I-APS ngokuvamile ayithinti isikhathi sakho sokuphila. Kodwa-ke, uma ihlule legazi lilimaza isitho esibalulekile, ikakhulukazi esimweni esifana ne-CAPS, lingabulala.
Udokotela usithola kanjani lesi sifo ngokunembile?
I-APS ivame ukutholakala ngemva kokwakheka kwehlule legazi noma ngemva kokuphuphuma kwesisu okuphindaphindiwe. Abanye abantu bangase babe nama-antiphospholipid antibodies kodwa bangalokothi babe nezimpawu.
Udokotela uzoqinisekisa ukuthi une-APS ngokuhlolwa kwegazi . Bazothatha isampula yegazi lakho bese behlola ukuthi kukhona yini izinhlobo ezintathu zama-antibodies okukhulunywe ngawo ngaphambili. Ukuze kuqinisekiswe lesi sifo, okungenani ukuhlolwa kwegazi okukodwa kumele kube nokutholakala kabili, okungaphezu kwezinyanga ezintathu.
Yiziphi izindlela zokwelapha lokhu?
Udokotela wakho uzoncoma ukwelashwa okunciphisa ingozi yokuqhekeka kwegazi. Ukwelashwa okuvame kakhulu yimithi yokunciphisa igazi, noma imithi yokunciphisa ukuqhekeka kwegazi .
| Uhlobo lwesidakamizwa | Indlela yokusebenzisa nokusebenza |
|---|---|
| Ukwelashwa okuvamile | |
| I-Heparin | Lona umuthi ofakwa ngemithambo yegazi (IV) osiza ekuncibilikiseni ihlule legazi uma ulaliswe esibhedlela. |
| I-Warfarin | Leli iphilisi oliphuza ngomlomo. Linciphisa igazi futhi livimbele ukwakheka kwamahlule egazi amasha. |
| I-aspirini | Udokotela wakho angase akuncome ukuthi uthathe i-aspirin ephansi ukuze uvimbele ukwakheka kwamahlule egazi emithanjeni yakho. |
| Ukwelashwa okusetshenziswa ngesikhathi sokukhulelwa | |
| I-Enoxaparin | Lona umjovo onikezwa ngaphansi kwesikhumba. Ngokuvamile unconywa kanye ne-aspirin ephansi ukuvimbela ukuphuphuma kwesisu. |
| I-immunoglobulin efakwa emthanjeni (IVIG) | Lokhu kwelashwa, okunikezwa ngemithambo yegazi, kulawula ukusebenza kwesimiso somzimba sokuzivikela futhi kunciphisa ingozi yokuphuphuma kwesisu. |
| Ama-Corticosteroids | Le mithi inciphisa ukuvuvukala emzimbeni futhi ilawula ukusebenza ngokweqile kwesimiso somzimba sokuzivikela. |
Uma ukhulelwe, lokhu kwelashwa kuphephile kuwe kanye nomntwana wakho, ngakho-ke asikho isidingo sokukhathazeka ngakho.
Masiqaphele nemiphumela emibi yemithi yokunciphisa igazi.
Uma uthatha imithi yokunciphisa igazi, umzimba wakho unamathuba amaningi okuphuma igazi. Ngakho-ke kudingeka uqaphele kakhulu ngalezi zimpawu. Uma unanoma iyiphi yalezi zimpawu , khuluma nodokotela wakho ngokushesha.
- Ukopha okuvela ezinsinini noma ekhaleni ngaphandle kwesizathu .
- Ukopha kakhulu kunokujwayelekile ngesikhathi sokuya esikhathini.
- Ukuhlanza okubomvu kancane noma okunombala wekhofi oqoshiwe .
- Igazi elibomvu elikhanyayo esitulweni noma esimnyama, indle ephuzi .
- Ubuhlungu besisu obukhulu noma ikhanda elibuhlungu kakhulu .
- Izinguquko ezisheshayo embonweni .
- Ukulahlekelwa yimizwa engalweni noma emilenzeni ngokuzumayo .
Izinto okufanele uzicabangele uma uhlala ne-APS
Into ebaluleke kakhulu uma uphila ne-APS ukuvimbela ukuqhekeka kwegazi. Ngenxa yalokhu, kubalulekile ukuthatha imithi yokunciphisa igazi ngendlela efanele.
Ngaphezu kwalokho, kubalulekile ukulawula ezinye izimo zempilo ezandisa ingozi yakho yokuqhekeka kwegazi. Uma unezinye zalezi zimo, khuluma nodokotela wakho bese uzilawula:
- Isifo sikashukela
- Umfutho wegazi ophakeme
- I-cholesterol ephezulu
- Ukukhuluphala ngokweqile
- Ezinye izifo ezizimele
Ukubhema kwandisa ingozi yokuqhekeka kwegazi, ikakhulukazi kumuntu onesifo esifana ne-APS.
Ingabe udinga ukuqaphela ngokudla nokuphuza?
Abantu abane-APS ngokuvamile akudingeki balandele ukudla okukhethekile. Kodwa-ke, uma uthatha umuthi i -Warfarin , kufanele uqaphele ngokudla okunothe nge-vitamin K (imifino eluhlaza njengespinashi). Ukudla ukudla okuningi okunothe nge-vitamin K ngesikhathi esisodwa kungandisa ingozi yakho yokuqhekeka kwegazi. Ngakho cela iseluleko kudokotela wakho.
Futhi, buza udokotela wakho mayelana nokusetshenziswa kotshwala. Utshwala bunciphisa igazi, ngakho-ke ukuluhlanganisa nemithi yokunciphisa igazi kungandisa umphumela.
Kufanele ngimbone nini udokotela?
Uma uthatha imithi yokunciphisa igazi, kufanele ubonane nodokotela wakho njalo ukuze ahlolwe igazi ukuqinisekisa ukuthi amazinga akho okujiya kwegazi angaphakathi kwesilinganiso esifanele.
Uma unethemba lokukhulelwa, kubaluleke kakhulu ukukhuluma nodokotela wakho ngakho kusenesikhathi futhi uthole iseluleko.
Kufanele ngiye nini eMnyangweni Wezimo Eziphuthumayo (i-ETU)?
Yiya eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela ngokushesha:
- Ngisola ukuthi unegazi eliqhekekile.Uma kwenzeka.
- Uma kuvela izimpawu zokuqhekeka kwegazi.
- Uma uphuma igazi ngendlela engalawuleki .
Umlayezo Wokuya Nawe Ekhaya
- I-Antiphospholipid Syndrome (APS) yisimo esanda ingozi yokuqhekeka kwegazi ngoba amasosha omzimba wakho ahlasela umzimba wakho.
- Lokhu akusikho okufanele ukwesabe, futhi kungalawulwa kahle ngokwelashwa okufanele (ikakhulukazi imithi yokunciphisa igazi).
- Nakuba ukuphuphuma kwesisu nezinye izinkinga kungenzeka ngesikhathi sokukhulelwa, kungenzeka ukubeletha izingane ezinempilo ngaphansi kokuqashwa okufanele kwezokwelapha.
- Uma ubona izimpawu zokuqhekeka kwegazi, njengobuhlungu besifuba, ubunzima bokuphefumula, noma ukuvuvukala kwemilenze, kubheke njengesimo esiphuthumayo bese uya esibhedlela ngokushesha.
- Kubaluleke kakhulu ukulandela imiyalelo kadokotela wakho ngqo nokuhlolwa njalo.
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