Ingabe uhlelo lokuzivikela lomzimba wakho luyadlala ngawe? Ake sifunde nge-Autoimmune Pancreatitis ngendlela elula!

Sinesimiso sokuzivikela esimangalisayo emizimbeni yethu, akunjalo? Yilokho esikubiza ngokuthi isimiso sokuzivikela. Sisivikela ngokulwa namagciwane, amabhaktheriya, kanye namagciwane abangela izifo. Kodwa cabanga, kuthiwani uma ngezinye izikhathi lesi simiso sethu sokuzivikela sidideka namangqamuzana amahle emizimbeni yethu bese siqala ukuwahlasela? Yilapho-ke kwenzeka khona, okubizwa ngokuthi "i-Autoimmune Pancreatitis". Kalula nje, isimiso sakho sokuzivikela siqala ukusebenza ngokumelene ne-pancreas yakho.

Kuyini "i-Autoimmune Pancreatitis"? Kalula nje...

Cabanga ngesimiso somzimba wakho sokuzivikela njengebutho elivikela izwe. Umsebenzi waleli butho ukuvikela izwe ezitheni zangaphandle (njengamagciwane namagciwane). Kodwa ku-`(Autoimmune Pancreatitis)`, leli butho lenza iphutha futhi lihlasele izakhamuzi ezingenacala zezwe lalo (okungukuthi, amangqamuzana aphilile kuma-pancreas) licabanga ukuthi liyizitha. Ngenxa yalokho, i-pancreas iyavuvukala, ilimale, futhi umsebenzi wayo uyaphazamiseka. Yilokhu esikubiza ngokuthi i-autoimmune pancreatitis .

Sivame kangakanani lesi sifo?

Empeleni, `(Autoimmune Pancreatitis)` yisifo esingavamile . Ngokuvamile sivela cishe kubantu abayizinkulungwane eziyikhulu. Uma sithatha izimo zokuvuvukala ze-pancreas zesikhathi eside (`i-pancreatitis engapheli`), cishe ama-2% kuphela awela kulesi sigaba `(Autoimmune Pancreatitis)`. Ngakho-ke, lesi akusona isifo esithinta wonke umuntu.

Ingabe kukhona izinhlobo ze-`(Autoimmune Pancreatitis)`?

Yebo, kunezinhlobo ezimbili ikakhulukazi ze-`(Autoimmune Pancreatitis)`. Ake sibone ukuthi ziyini.

1. Uhlobo 1 lwe-Autoimmune Pancreatitis

Lolu uhlobo oluvame kakhulu . Kulokhu, sineprotheni ebizwa ngokuthi `(Immunoglobulin G4)` noma `(IgG4)` emizimbeni yethu. Lolu `(IgG4)` luhlobo lwe-antibody. Uma kukhona ukuvuvukala noma ukuvuvukala noma kuphi emzimbeni, izinga lalolu `(IgG4)` liyakhuphuka.

Kodwa kulolu hlobo lokuqala, inkinga ayikho kuphela kuma-pancreas. Ingathinta nezinye izitho zomzimba wethu. Isibonelo:

• Amapayipi enyongo: Lawa ngamapayipi afana namapayipi athwala inyongo esuka esibindini iye emathunjini amancane.
• Amapayipi ezinso: Amapayipi ezinso.
• Isibindi
• Amaphaphu
• Inyongo
• Izindlala zamathe
• Indlala yegilo

Ukuvuvukala nomonakalo kungavela nasezindaweni ezinjengalezi.

2. Uhlobo 2 lwe-Autoimmune Pancreatitis

Lolu hlobo luthinta kuphela i-pancreas . Okwenzekayo lapha ukuthi uhlobo lweseli elimhlophe legazi elibizwa ngokuthi "ama-neutrophils" lulimaza i-pancreas kanye ne-pancreatic ducts. Lesi simo sivame ukubonakala kubantu abasebasha.Banamathuba amaningi okuba nesifo sokuvuvukala kwamathumbu (IBD).

Yiziphi izimbangela ze-`(Autoimmune Pancreatitis)`? Ingabe zikhona izinto eziyingozi?

Abacwaningi basazama ukuthola imbangela eqondile , kodwa imvamisa ivele kubantu abaneminyaka ephakathi kuka-50 no-60. Kodwa-ke, ingenzeka kusenesikhathi. Amadoda anamathuba aphindwe kabili okuthola lesi sifo kunabesifazane.

Ngezinye izikhathi, kucatshangwa ukuthi kuyindlela umzimba osabela ngayo ekuthelelekeni ngamagciwane. Ngaphezu kwalokho, abantu abanezinye izifo zokuzivikela komzimba basengozini enkulu yokukuthola lokhu. Isibonelo:

• (I-Hashimoto's thyroiditis): Lokhu kubangela ukuthi indlala yegilo ingasebenzi kahle (i-hypothyroidism).
• (Isifo samathumbu esivuvukalayo - IBD): Ikakhulukazi izimo ezifana `(ulcerative colitis)`.
• (I-cholangitis eyinhloko yenyongo)
• I-Retroperitoneal fibrosis: Ukwakheka kwezicubu ezifana nezibazi olwelwesini lwangemuva kwesisu.
• I-rheumatoid arthritis: Ukuvuvukala kwamalunga.
• (I-Sarcoidosis)
• (Isifo sikaSjögren)

Uma unezinye izimo zokuzivikela komzimba ezinjengalezi, kuwumqondo omuhle ukukhathazeka kancane nge-Autoimmune Pancreatitis.

Yiziphi izimpawu ze-`(Autoimmune Pancreatitis)`?

Ezigabeni zokuqala zalesi sifo , kungase kungabi nazimpawu . Kodwa-ke, njengoba lesi sifo siqhubeka, imigudu ye-pancreatic iqala ukuncipha, okuvimbela ama-enzyme akhishwa yi-pancreas ukuthi akwazi ukudlula kahle.

Ukuvaleka komsele we-pancreatic kungadala izimpawu ezifana nalezi:

• Ubuhlungu besisu esingaphezulu
• Ubuhlungu obuphakathi emhlane
• Uhudo
• Isicanucanu/ukuhlanza
• Ukwehlisa isisindo

Okubalulekile: Ezinye zalezi zimpawu zingabonakala nakumdlavuza we-pancreatic. Ngakho-ke, uma unalezi zimpawu, kuwukuhlakanipha ukungesabi bese ubona udokotela ngokushesha ukuze uthole ukuthi inkinga iyini ngempela . Ukuba ne-`(Autoimmune Pancreatitis)` akusho ukuthi unomdlavuza.

Ngaphezu kwalokho, i-autoimmune pancreatitis ingabangela ukuvuvukala, ukukhula okungenawo umdlavuza, kanye nama-cyst agcwele uketshezi kuma-pancreas. Uma lokhu kuvuvukala, amaqhubu, noma ama-cyst kwenzeka ekhanda le-pancreas yakho, kungavimba i-bile duct, okungavimbela i-bile ukuthi ingagelezi kahle emathunjini amancane. I-Bile iqukethe umbala obizwa ngokuthi i-bilirubin. Uma le bilirubin iqoqana egazini, ingabangela i-jaundice.Isikhumba kanye namhlophe emehlweni kuba phuzi (i-jaundice), futhi ungase uzizwe ukhathele. Uma i-bilirubin ikhula emchameni , umchamo uba mnyama . Uma i-bilirubin ikhishwa emathunjini , indle ingaba nombala okhanyayo .

Yiziphi izinkinga ezingaba khona ze-`(Autoimmune Pancreatitis)`?

Ukuvuvukala okungapheli kwe-pancreas kungabangela isicanucanu, ukwehla kwesisindo, kanye nobuhlungu obuqhubekayo esiswini esingaphezulu nasemhlane. Futhi, uma amaseli akhiqiza i-insulin ku-pancreas elimele , isifo sikashukela singakhula.

Ama-antibodies e-IgG4 angahlasela hhayi kuphela ama-pancreas, kodwa nezinye izitho zomzimba, ikakhulukazi ku-Type 1. Izitho ezinjalo zifaka:

• Amapayipi enyongo
• Izindlala zamathe
• Izindlala ze-Lacrimal
• Indlala yegilo (`Igilo`)
• Izinso
• Inhliziyo
• Amaphaphu kanye ne-pleura (ulwelwesi lwamaphaphu)

I-Autoimmune Pancreatitis ihlolwa kanjani?

Ukuze uhlole lesi sifo ngokunembile futhi uqiniseke ukuthi akusona umdlavuza we-pancreatic, kuzodingeka ukuhlolwa okuningana. Kuzodingeka ube nokuhlolwa okufana nalokhu:

• Ukuhlolwa kwegazi: Lokhu kuhlola amazinga aphezulu kakhulu e-IgG4, ukusebenza kwesibindi, kanye namazinga ezinhlobo ezithile zamaseli egazi.
• Ukuhlolwa kwezithombe: Lokhu kuhlola usayizi we-pancreas, ukuthi ngabe kukhona yini izibazi, noma ukuthi imibhobho inciphile yini. Izibonelo zalokhu kuhlolwa yi-`(CT scan)` kanye ne-`(MRI scan)`.
• I-Biopsy: Lokhu kuhilela ukuthatha ingxenye encane yezicubu ezivela ku-pancreas yakho bese uyihlola ngaphansi kwe-microscope. Lokhu kuvame ukwenziwa ngenqubo ye-endoscopic encane kakhulu ebizwa ngokuthi i-Endoscopic Ultrasound (EUS). Kule nqubo, udokotela wakho ufaka ithubhu elide, eliguquguqukayo (elinomshini wokukhanya kanye ne-ultrasound kolunye uhlangothi) esiswini sakho nasemathunjini ukuze abheke i-pancreas yakho. Isampula ye-biopsy ibe isithathwa esiswini sakho noma emathunjini. Ngezinye izikhathi, udokotela ohlinzayo angadinga ukwenza ukusika okuncane esikhumbeni sakho (i-laparoscopy) ukuze athathe isampula ye-biopsy.
• Isivivinyo se-Corticosteroid: Lokhu kusiza futhi ukuqinisekisa ukuxilongwa. Unikezwa ama-steroid isikhathi esifushane ukuze ubone ukuthi amazinga akho e-IgG4 ayancipha yini nokuthi ukuhlolwa kwakho kwezithombe kuyathuthuka yini.

Iphathwa kanjani i-`(Autoimmune Pancreatitis)`?

Ngokumangalisayo, kubantu abambalwa kakhulu, lesi sifo siphela ngokwaso ngaphandle kokwelashwa . Kodwa kwabaningi, ukwelashwa kuyadingeka .

I-Autoimmune Pancreatitis iphathwa kakhulu nge-corticosteroids.Uhlobo lomuthi olubizwa ngokuthi i-steroid. Isibonelo, umuthi ofana ne-`(prednisone)` noma `(prednisolone)`. Le mithi isebenza ngokunciphisa ukuvuvukala nokuzola isimiso somzimba sokuzivikela esisebenza ngokweqile. Ukwelashwa kuvame ukuqala ngomthamo omkhulu wama-steroid. Bese umthamo uncishiswa kancane kancane (`uncishisiwe`).

Uma ungenazo izinkinga, ngokuvamile awudingi ukwelashwa okwengeziwe. Ukwelashwa okudingekayo kuncike ohlotsheni lwezinkinga. Uma kukhona ukuncishiswa komsele we-pancreatic (`ukuncishiswa komsele`), inqubo ingenziwa ukuvula umsele bese uwuqinisa ngedivayisi ene-hollow mesh (`stent`).

Ngingakuvimbela yini ukuthola i-`(Autoimmune Pancreatitis)`?

Empeleni, akukho ongakwenza ukuvimbela lesi sifo ukuthi singabi khona ngoba siyinkinga ohlelweni lwethu lokuzivikela komzimba.

Iyini inhloso yabantu abane-`(Autoimmune Pancreatitis)`?

Iningi labantu liyalulama kahle ngemva kokwelashwa nge-corticosteroid , futhi azikho izinkinga. Ukuba ne-autoimmune pancreatitis akuthinti isikhathi sakho sokuphila .

Kodwa-ke, `(Autoimmune Pancreatitis)` ingaphinde ivele (iphinde ivele) . Lokhu kuvame kakhulu kubantu abanohlobo lokuqala (`Uhlobo 1`). Lesi sifo cishe sizophinde sivele eminyakeni emithathu yokuqala ngemva kokuxilongwa. Umuntu onesifo siphinde sivele kungenzeka kakhulu ukuthi abe nezinkinga.

Kwenzekani uma lesi sifo siphinde sibuye?

Uma kulawulwa ngempumelelo, ngisho nalabo abanezifo eziphindaphindayo bangaphila impilo esebenzayo nenempilo .

Kungase kudingeke uqale ukusebenzisa ama-corticosteroids futhi. Abanye abantu baqhubeka nokwelashwa ngama-steroid iminyaka eminingana ukuze bavimbele izimpawu ukuthi zingabuyi. Odokotela bangase bazame neminye imithi elapha isimiso somzimba sokuzivikela esisebenza ngokweqile (imithi yokuvikela amasosha omzimba kanye neyokucindezela amasosha omzimba).

Ngizozizwa kanjani ngesikhathi sokwelashwa?

Eminye imiphumela emibi ingase ivele uma usebenzisa ama-steroid. Isibonelo, ukucasuka kwesisu, ukwanda kwesifiso sokudla, ukungaphumuli, kanye nobunzima bokulala. Le miphumela emibi ingaba yisiphazamiso esincane empilweni yansuku zonke, kodwa ingeyesikhashana . Ukuze uthole okuningi ekwelashweni kwakho kwe-Autoimmune Pancreatitis, kubalulekile ukuqhubeka nokuthatha ama-steroids njengoba kunqunywe udokotela wakho .

Uma imiphumela emibi ikhathaza kakhulu ukuba ungayibekezelela, qiniseka ukuthi wazisa udokotela wakho ngaphambi kokuyeka ukwelashwa. Angase akunikeze ukwelashwa okwengeziwe ukuze akusize uthole impumuzo, noma ashintshe uhlelo lwakho lokwelashwa.

Ngingabuyela nini emisebenzini evamile ngemva kokwelashwa kwe-`(Autoimmune Pancreatitis)`?

Ukwelashwa ngama-steroid kuvame ukuqeda izimpawu ze-`(Autoimmune Pancreatitis)` zingakapheli amasonto ambalwa.Abantu abaningi babuyela emisebenzini yabo evamile ngemva kokuba izimpawu zabo seziphelile.

I-Autoimmune Pancreatitis yisimo sokuvuvukala esingavamile esingathinta ukusebenza kwe-pancreas. Ukubona udokotela ojwayelene nezifo ze-pancreatic kungakusiza ukuthi uthole ukunakekelwa okungcono kakhulu okudingayo. Iningi labantu liyalulama ngokugcwele ngemva kokuthatha ama-steroid . Abanye abantu bangadinga ukwelashwa okwengeziwe kwe-Autoimmune Pancreatitis ukuze bathole impumuzo yesikhathi eside.

Okokugcina, khumbula lokhu (Umyalezo Wokuya Ekhaya)

• I-Autoimmune Pancreatitis yisimo esingavamile lapho amasosha omzimba wakho ehlasela khona ama-pancreas akho.
• Uma unezimpawu ezifana nobuhlungu besisu, ukwehla kwesisindo, noma i-jaundice , qiniseka ukuthi ufuna iseluleko sikadokotela .
• Lokhu akuwona umdlavuza we-pancreatic, kodwa izimpawu ziyafana, ngakho-ke ukuxilongwa okufanele kubalulekile .
• Ukwelashwa okuyinhloko yi-corticosteroids.
• Abantu abaningi bayalulama kahle ngokwelashwa, kodwa lesi sifo singaphinde sibuye.
• Kubaluleke kakhulu ukulandela imiyalelo kadokotela ngqo ukuze ululame ngokushesha .

Khumbula, awuwedwa. Kuvamile ukuba nemicabango eminingi edlula engqondweni yakho esimweni esinjengalesi. Ngakho-ke, vula ingqondo nodokotela wakho futhi ubuze imibuzo yakho. Bakhona ukuzokusiza.

` I-Autoimmune Pancreatitis, i-Pancreatitis, i-Autoimmune, i-IgG4, impilo ye-Pancreas, i-Pancreatitis Sinhala, impilo yokugaya ukudla