I-Metformin yesifo sikashukela: Okudingeka Ukwazi (Metformin)

Uma unesifo sikashukela sohlobo lwesibili, udokotela wakho cishe uzokunikeza umuthi obizwa ngokuthi i-Metformin. Lo umuthi obaluleke kakhulu osetshenziswa kakhulu ngabantu abanesifo sikashukela ezweni lethu nasemhlabeni jikelele. Ngakho-ke, kungani lo muthi ubaluleke kangaka? Usebenza kanjani emizimbeni yethu? Yimiphi imiphumela emibi engaba khona? Yiziphi izinto okufanele uzesabe? Ake sixoxe ngakho konke lokhu kalula, njengokungathi sikhuluma nomngane namuhla.

I-metformin isebenza kanjani emzimbeni?

Kalula nje, i-metformin isiza ukulawula amazinga kashukela egazini lakho ngezindlela ezintathu eziyinhloko. Cabanga ngayo njengomphathi ohlakaniphile.

1. Kunciphisa ukukhiqizwa kukashukela yisibindi: Ngokuvamile, isibindi sethu sikhiqiza ushukela ) umzimba wethu owudingayo. Kumuntu onesifo sikashukela, le nqubo ingaphezu kwamandla. I-Metformin inikeza isibindi "isignali" ethi, "Kulungile, manje yehlisa ukukhiqizwa kancane, kakade kunoshukela omningi egazini."

2. Kwandisa ukuzwela komzimba ku-insulin: Inkinga enkulu ku-diabetes ukumelana ne-insulin. Lokhu kusho ukuthi noma kukhona i-insulin emzimbeni, amaseli omzimba, ikakhulukazi amaseli emisipha, awasabeli kahle kuleyo insulin. I-Metformin isiza la maseli ukuthi azwele kakhulu ku-insulin. Ngemuva kwalokho, ushukela ontanta egazini ungangena kalula emisipheni futhi usetshenziswe njengamandla.

3. Kunciphisa ukumuncwa kukashukela ekudleni: Umzimba umunca ushukela ekudleni esikudlayo emathunjini. I-Metformin inciphisa isivinini kanye nenani likashukela elimuncwa kula mathumbu.

Lezi zindlela ezintathu zodwa zingasiza ekwehliseni isivivinyo sakho se-A1c , okuyisilinganiso samazinga akho ajwayelekile kashukela egazini ezinyangeni ezimbalwa ezedlule. Lo muthi ungasiza futhi ekubambezeleni ukuqhubekela phambili kwesifo sikashukela esingakafiki ezingeni lesifo sikashukela.

Izinhlobo nezinhlobo zeMetformin

I-Metformin itholakala ngaphansi kwamagama amaningi emikhiqizo ehlukene. Udokotela wakho kungenzeka ukuthi ukunike yona ngaphansi kwamagama anjenge-'Glucophage', 'Fortamet', 'Riomet'. Lawa atholakala ngefomu lamaphilisi kanye nefomu loketshezi.

Ngezinye izikhathi i-metformin inikezwa kanye nomunye umuthi wesifo sikashukela. Isibonelo, i-Janumet iyiphilisi elihlanganisiwe elihlanganisa i-sitagliptin ne-metformin. Udokotela wakho uzonquma ukuthi yiluphi uhlobo kanye nomthamo okufanele uwuthathe.

Yimiphi imiphumela emibi evame kakhulu?

Njenganoma yimuphi umuthi, i-Metformin ingaba nemiphumela emibi. Kodwa ungakhathazeki , eminingi yayo mincane futhi izophela ngokuhamba kwesikhathi njengoba umzimba wakho ujwayela umuthi. Imiphumela emibi evame kakhulu ukuphazamiseka kwesisu.

Into ebaluleke kakhulu ukungayeki ukuthatha imithi ngokuzumayo ngenxa yale miphumela emibi. Khuluma nodokotela wakho ngalokhu. Uzokutshela ukuthi ungayiphatha kanjani.

Indlela engcono kakhulu yokunciphisa lokhu kungakhululeki ukuphuza umuthi ngesikhathi sokudla noma ngemva kokudla . Kulula ukuwuphuza esiswini kunokuwuphuza ungenalutho esiswini.

Enye into ukuthi igobolondo lamanye amaphilisi akhululwa isikhathi eside (i-ETU) (lezi yizinhlobo ezikhipha umuthi emzimbeni ngokuhamba kwesikhathi) ngezinye izikhathi lingaphuma nendle. Ungakhathazeki uma ubona lokhu. Umuthi usungene emzimbeni.

Imiphumela emibi engavamile kodwa emibi kakhulu

Lezi azivamile ukubonwa, kodwa kubaluleke kakhulu ukuziqaphela.

1. I-Lactic Acidosis

Lona umphumela omubi kakhulu kodwa ongavamile we-metformin. Kwenzeka lapho ikhemikhali ebizwa ngokuthi i-lactic acid inqwabelana emizimbeni yethu. Kwenzeka kubantu abambalwa kakhulu. Abantu abalandelayo basengozini enkulu:

• Abantu abanesifo sezinso noma sesibindi
• Abantu abaphuza utshwala ngokweqile
• Abantu abanezinkinga zenhliziyo ezinzima
• Abantu abaphelelwe amanzi emzimbeni ngenxa yomkhuhlane, isifo sohudo, noma ukuhlanza

Qaphela lezi zimpawu:

Ngaphezu kobuhlungu besisu, isiyezi, kanye nokuzizwa unesizungu, uma uzwa ukungakhululeki noma ukubanda okungajwayelekile ezithweni zakho noma ushintsho ekushayeni kwenhliziyo yakho , shayela udokotela wakho ngokushesha noma uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze.

2. Ukuntuleka kweVithamini B12

Abanye abantu bangase babe namazinga aphansi e-vitamin B12 uma bethatha i-metformin isikhathi eside. Lokhu kungandisa izimpawu ze-peripheral neuropathy, eseyisici esiyingozi esibangela isifo sikashukela. Kungabangela futhi i-anemia, noma ukulahlekelwa igazi.

Ngakho-ke, kuwukuhlakanipha ukukhuluma nodokotela wakho futhi uhlolwe amazinga akho e-vitamin B12 njalo.

3. I-Hypoglycemia - ushukela wegazi ophansi

Akuvamile kakhulu ukuthi umuntu othatha iMetformin eyedwa abe noshukela wegazi ophansi kakhulu. Kodwa-ke, uma uthatha eminye imithi yesifo sikashukela (isib. iGliclazide, i-Insulin) neMetformin, uvivinya umzimba ngokweqile, noma ungadli kahle, ushukela wakho wegazi ungase wehle kakhulu. Uma uzwa izimpawu ezifana nokujuluka, ukuthuthumela, indlala enkulu, noma isiyezi, yidla okuthile okumnandi (isipuni sikashukela, uswidi) ngokushesha.

Ungayiphatha kanjani imiphumela emibi?

Kunezinto eziningana ongazenza ukuze ugweme noma unciphise imiphumela emibi eminingi.

• Qala ngomthamo ophansi: Udokotela wakho ngokuvamile uzoqala ngomthamo ophansi kakhulu kuqala, bese ekhulisa umthamo kancane kancane njengoba umzimba wakho ulungisa.
• Thatha umuthi kanye nokudla: Lena yindlela engcono kakhulu yokunciphisa ukungakhululeki esiswini.
• Buza ngohlobo lwe-Extended-Release (ETU) : Lolu hlobo lwephilisi luthathwa kanye ngosuku. Njengoba umuthi ukhishwa emzimbeni ngokuhamba kwesikhathi, imiphumela emibi efana nokuqunjelwa kanye nesicanucanu ayivamile. Uma unenkinga enkulu ngephilisi elivamile, buza udokotela wakho ukuthi ungashintshela kulolu hlobo.

I-Metformin neminye imithi

I-Metformin ingasebenzisana neminye imithi oyithathayo, ngakho-ke kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo (kufaka phakathi amavithamini).

Ikakhulukazi, uma uhlolwa ngokujova idayi yokuhlukanisa, njenge-CT scan noma i-MRI, kungadingeka uyeke ukuthatha i-Metformin ezinsukwini ezimbalwa ngaphambi kwalokho. Yazisa abasebenzi bezokwelapha abafanele kusenesikhathi.