Othile emndenini wakho, mhlawumbe umama wakho othandekayo, ubaba, ugogo noma u-anti, kungenzeka ukuthi unesifo i-Alzheimer's. Noma mhlawumbe unesifiso sokufunda okwengeziwe ngalesi sifo. I-Alzheimer's iyindlela evame kakhulu ye-dementia, isimo lapho amakhono okucabanga njengenkumbulo, amakhono okuxazulula izinkinga, kanye nolimi elahleka kancane kancane. Lokhu kungenza kube nzima ukwenza imisebenzi yansuku zonke.
Isici esikhulu sengozi yesifo i-Alzheimer's ukuguga. Nakuba imithi yamanje ingalawula izimpawu ngezinga elithile, ayikwazi ukuvimba lesi sifo ngokuphelele. Yingakho abacwaningi befuna izindlela ezintsha zokwelapha ezinganciphisa ukuqhubeka kwalesi sifo. Namuhla, sizokhuluma ngezimbili zalezi zindlela zokwelapha, ukuvuselela ubuchopho. Kalula nje, lezi zindlela zokwelapha zisebenzisa amagagasi kagesi noma amagnetic ukuze "zivule" noma "zivale" umsebenzi wezingxenye ezithile zobuchopho.
Kuyini ukwelashwa kwe-rTMS (Repetitive Transcranial Magnetic Stimulation)?
Lokhu kungenye yezindlela ezintsha zokwelapha ezihlolwa iziguli ezine-Alzheimer's. Kuhilela ukusebenzisa i-external magnet ukuze kusebenze ingxenye ethile yobuchopho, ngaphandle kokuhlinzwa. Kubizwa ngokuthi "okuphindaphindayo" ngoba ukwelashwa kwenziwa izinsuku ezinhlanu ngesonto, nsuku zonke amasonto amane kuya kwayisithupha.
Cabanga uhleli esihlalweni esivamile. Udokotela ubeka i-coil kagesi phezu kwekhanda lakho. Uma ivuliwe, kuzwakala sengathi i-tukanawak encane ishaya ibunzi lakho ngomsindo othi "chofoza" "chofoza" ohlala imizuzwana embalwa. Akudingi i-anesthesia (ukuthulisa ikhanda lakho). Njengoba kungahlinzwa, kungenziwa ehhovisi likadokotela noma emtholampilo.
Akucaci ngokuphelele ukuthi i-rTMS isebenza kanjani ngempela ezigulini ezine-Alzheimer's. Abacwaningi bakholelwa ukuthi ukuvuselela ubuchopho ngale ndlela kungasheshisa noma kwehlise ijubane lomsebenzi wobuchopho ohlobene nenkumbulo nokucabanga.
Kuphumelela kangakanani lokhu?
Impumelelo yokwelashwa kwe-rTMS incike ezintweni eziningana. Isibonelo, ukukhuthazwa okuvamise ukuba ngaphansi kuye kwabonakala kunciphisa umsebenzi wobuchopho, kuyilapho ukukhuthazwa okuvamise ukuba phezulu kuye kwabonakala kukhulisa lokho. Futhi, indawo yobuchopho eqondiswe ukwelashwa kanye nanoma yimiphi eminye imithi isiguli esiyithathayo ingathinta imiphumela.
Ngokuvamile, ukukhuthazwa okuvame kakhulu kuye kwabonakala kusebenza kakhulu kubantu abanesifo sokulahlekelwa yingqondo esincane kunalabo abanesifo sokulahlekelwa yingqondo esibi kakhulu. Ngezinye izikhathi, imiphumela emihle ibonakala ngokushesha ngemva kokwelashwa, kodwa kwabanye abantu, kungathatha amasonto afinyelela kwayi-6 ukubona imiphumela. Lezi zinzuzo zingase zihlale izinyanga ezi-3 noma ngaphezulu.
Ngezinye izikhathi lokhu kwelashwa kwe-rTMS kuyindlela yokuqeqeshwa kwengqondo kobuchopho.Kwenziwa ndawonye. Okusho ukuthi, ukuhlinzeka ngemisebenzi ehlukahlukene kanye nokuzivocavoca ukuze kuthuthukiswe ukusebenza kobuchopho. Uma lokhu kokubili kwenziwa ndawonye, kutholakale imiphumela engcono, ikakhulukazi ezigulini ezine-Alzheimer's ezithambile kuya kweziphakathi.
Okubalulekile, cishe ingxenye yeziguli ze-Alzheimer's zihlushwa ukucindezeleka. I-rTMS iyindlela yokwelapha ukucindezeleka evunyelwe yi-FDA. Ngakho-ke, kunzima ukuhlukanisa ukuthi inzuzo yokwelashwa kwe-rTMS yeziguli ze-Alzheimer's ibangelwa yisifo sangempela noma ukucindezeleka okuhambisanayo.
| Imiphumela emibi kanye nezinkinga zokwelashwa kwe-rTMS | Incazelo |
|---|---|
| Imiphumela emibi evamile | Ukungakhululeki endaweni ekhanga ugesi, ukuqaqamba emhlathini, ekhanda, noma ebusweni, ikhanda elibuhlungu, kanye nesiyezi kungase kube khona. |
| Imiphumela emibi emibi kodwa engavamile | Ukuquleka kungase kwenzeke kaningi. Akukaziwa okuningi ngemiphumela emibi yesikhathi eside okwamanje. |
| Izinkinga ngezinkinga | Ngokusho kwabanye abacwaningi, kunokukhathazeka ngokuthi ukukhuthazwa okuvamile kungase kusenze sibe sibi kakhulu isifo i-Alzheimer's. Kudingeka ucwaningo olwengeziwe ngalokhu. |
Kuyini Ukukhuthazwa Kobuchopho Obujulile (i-DBS)?
Ngokungafani ne-rTMS, i-DBS iyindlela yokwelapha ehlaselayo edinga ukuhlinzwa kobuchopho. Lesi yisinyathelo esikhulu sokuqhubekela phambili. Kulokhu kuhlinzwa, kufakwa ama-electrode amabili ebuchosheni bakho. Njenge-pacemaker, ama-generator amabili amancane alawula la ma-electrode afakwa ngaphansi kwesikhumba sesifuba sakho.
Ngaphambi kokuhlinzwa, uzobe uhlolwe ikhanda lakho nge-MRI. Uzobe uphapheme ngesikhathi sokuhlinzwa. Ungakhathazeki, ikhanda lakho lizoba ne-numbness (i-local anesthetic) ukuze ungazizwa ubuhlungu. Ngenxa yokuthi ubuchopho abuzizwa ubuhlungu, udokotela angasebenzisa izithombe ze-MRI ukubeka ama-electrode ezindaweni ezifanele. Ngemuva kwalokho, uzofakwa ngaphansi kwe-anesthesia ejwayelekile futhi i-generator kanye nezintambo eziwaxhuma kuma-electrode ebuchosheni bakho zizofakwa esifubeni sakho. Ngemva kokuhlinzwa, le divayisi izohlinzeka ngokukhuthaza okuqhubekayo ebuchosheni bakho.
Ukwelashwa nge-DBS kwaqala ukusetshenziswa ekwelapheni izimpawu zesifo sikaParkinson, njengokuthuthumela nokuqina. Kwakungemva kokuba isiguli esisodwa esathola ukwelashwa kwe-DBS ngenxa yokukhuluphala sibonise ukuthuthuka kwenkumbulo lapho abacwaningi baqala khona ukuphenya ukuthi ingasetshenziswa yini nesifo sika-Alzheimer.
Kuphumelela kangakanani lokhu?
Izifundo zakuqala zibonisa ukuthi i-DBS iyindlela yokwelapha ethembisayo. Kodwa-ke, impumelelo yayo incike esigabeni sesifo kanye nohlelo lokwelashwa (indawo yobuchopho eqondiswe kuyo, amandla okukhuthaza).
Ngokuvamile, ukwelashwa kwe-DBS kusebenza kahle kakhulu uma kusetshenziswa ezigabeni zokuqala zesifo (i-Alzheimer's yesigaba sokuqala) . Abantu abatholakale benalesi sifo ngemva kweminyaka engu-65 (ekuqaleni kwesikhathi) bangase bazuze, okusho ukuthi lesi sifo singase sinciphise ukuqhubekela phambili kwaso. Kodwa ngokumangazayo, abantu abatholakale benalesi sifo ngaphambi kweminyaka engu-65 (ekuqaleni kwesikhathi) abakayiboni inzuzo enkulu kulokhu kwelashwa.
| Imiphumela emibi kanye nezinkinga zokwelashwa kwe-DBS | |
|---|---|
| Izinkinga ezihlobene nokuhlinzwa | |
| Ukuhlinzwa kungabangela ukopha, ukutheleleka, kanye nokungasebenzi kahle kwezingxenye zesifuba. | |
| Imiphumela emibi ehlobene nokukhuthaza | |
| |
| Eminye imiphumela emibi engaba khona | |
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Eminye imiphumela emibi (ikhanda elibuhlungu, isifo sohudo, ukuhlanza) izophela ngokuhamba kwesikhathi, kodwa kubalulekile ukukhumbula ukuthi i-DBS iyindlela yokwelapha eyingozi.
Umlayezo Wokuya Nawe Ekhaya
- Isifo i-Alzheimer's siyisifo esiqhubekayo. Nakuba imithi yamanje ingalawula izimpawu, ayikwazi ukwelapha lesi sifo.
- I-rTMS iyindlela yokuvuselela ubuchopho engahlinzwa, enobungozi obuphansi engaba wusizo kubantu abasesigabeni sokuqala salesi sifo, kodwa isesesigabeni sokucwaninga.
- I-DBS iyindlela yokwelapha engathi sína neyingozi edinga ukuhlinzwa kobuchopho. Ingase futhi ibe usizo kwabanye abantu abasesigabeni sokuqala salesi sifo, kodwa ayikasetshenziswa kabanzi okwamanje.
- Zombili lezi zindlela zokwelapha zisahlolwa isifo i-Alzheimer's futhi azivamile ukunikezwa imithi.
- Into ebaluleke kakhulu ukuthi uma othile emndenini wakho enesifo i-Alzheimer's, ngaphambi kokunquma nganoma yiluphi uhlobo lokwelashwa, khuluma nodokotela wakho ngokucophelela futhi uqonde ukuthi yini efanelana kangcono nesimo sesiguli.
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