Umhlahlandlela Olula Weziqhubu Ezingavamile Ezingalweni Nasemilenzeni: Okufanele Ukwazi Nge-Clear Cell Sarcoma | Nirogi Lanka

Uke waphawula yini iqhubu noma inqwaba engavamile ngaphansi kwesikhumba engalweni noma emlenzeni wakho engeke iphele? Ungase uthole ukuthi ayibangeli ubuhlungu uma uyithinta, kodwa uma uzizwa ikhula kancane kancane, kubalulekile ukunaka kakhulu. Namuhla, eNirogi Lanka , sifuna ukuxoxa ngohlobo lomdlavuza olungavamile kodwa olubalulekile olungaba nalezi zimpawu. Yisimo esaziwa ngokuthi i-Clear Cell Sarcoma , futhi sikholelwa ukuthi kubalulekile ukuthi ube nolwazi oluphelele ngaso.

Kuyini i-Clear Cell Sarcoma?

Kalula nje, i-Clear Cell Sarcoma uhlobo lomdlavuza olungavamile kakhulu oluvela ezicutshini ezithambile zomzimba wakho. Lungowomndeni we -sarcoma . Lawa mathumba avame ukukhula emilenzeni yakho, ikakhulukazi eduze kwemisipha - imicu eqinile yezicubu exhumanisa imisipha yakho namathambo akho - kanye nasezicutshini ezithambile ezizungezile imisipha yakho.

Njengezinye izinhlobo eziningi zomdlavuza, ukutholakala kusenesikhathi kubalulekile ekwelashweni okuphumelelayo ngaphambi kokuba kusakazekele kwezinye izingxenye zomzimba wakho. Odokotela bavame ukuphatha lesi simo ngokuhlinzwa , okuvame ukuhlanganiswa nokwelashwa ngemisebe , futhi kwezinye izimo, i-chemotherapy . Ngeshwa, lolu hlobo lomdlavuza lunamathuba aphezulu okuphinda lubuye ngisho nangemva kokwelashwa. Ngenxa yalokhu, abacwaningi bezokwelapha eNirogi Lanka nasemhlabeni wonke baqhubeka nokusebenza ukuthola izindlela zokwelapha eziphumelela kakhulu.

I-Clear Cell Sarcoma ithinta kanjani umzimba wakho?

I-Clear Cell Sarcoma ivame ukuqala ngaphakathi kwezicubu ezithambile eduze kwemisipha yakho, imisipha, noma i- fascia — izicubu ezincane neziqinile ezixhumanisayo ezisebenza njengesivikelo esisekelayo esizungeza imisipha nezakhiwo zakho.

Ekuqaleni, ungase ungaboni zimpawu. Kodwa-ke, njengoba isimila sikhula, ungase uzizwe iqhubu eliqinile ngaphansi kwesikhumba emlenzeni noma onyaweni lwakho. Nakuba lokhu kungase kuzwakale njengeqhubu elivela ekulimaleni okudala, umehluko obalulekile ukuthi leli qhubu alinyamalali ngokuhamba kwesikhathi . I-Clear Cell Sarcoma ivame ukukhula kancane kakhulu, kodwa ngesikhathi isiba buhlungu ngaphansi kwesikhumba sakho, kungenzeka ukuthi isiqalile ukusabalala kwezinye izindawo zomzimba.

Uma ubona iqhubu emlenzeni wakho bese uzitshela ukuthi, "Mhlawumbe ukulimala nje," sicela uqaphele. Uma lelo qhubu liqhubeka amasonto noma izinyanga—noma liqala ukukhula—ungalindi. Funa iseluleko sezokwelapha kumhlinzeki wakho wezempilo ngokushesha.

I-Clear Cell Sarcoma ingasakazeka kuphi?

I-Clear Cell Sarcoma ingasakazeka kwezinye izingxenye zomzimba, ikakhulukazi:

• Umgudu wakho wokugaya ukudla
• Amaphaphu akho
• Uhlelo lwakho lwe-lymphatic , okuhlanganisa ama-lymph node akho kanye nemithambo ye-lymph.

Ingabe lesi yisimo esivamile?

Cha, akuvamile neze. Ngisho nama-sarcoma njengeqembu awavamile. Isibonelo, e-United States, kunezimo ezintsha ezingaba ngu-1,600 ze-sarcoma yezicubu ezithambile ezitholakala minyaka yonke, ezibalelwa cishe ku-1% yazo zonke izifo zomdlavuza zabantu abadala. I-Clear Cell Sarcoma imelela cishe u-1% walezo zimo ezingavamile. Lokhu kugcizelela ukuthi lesi simo asivamile kangakanani ngempela.

Ubani osengozini enkulu?

Nakuba i-Clear Cell Sarcoma ingavela kunoma yimuphi ubudala, ivame ukutholakala kubantu abadala abasebasha abaneminyaka ephakathi kwengu-15 nengu-40 ubudala , kanye nokwanda okukhulu kwesifo phakathi kweminyaka yakho yama-20 neyama-30.

Ziyini izimpawu?

Njengoba kushiwo, uphawu oluvame kakhulu yiqhubu eliqinile nelihlala njalo ngaphansi kwesikhumba somlenze noma unyawo lwakho. Lesi sigaxa singaba buhlungu noma singabi buhlungu. Kodwa-ke, uma sihlala lapho futhi sibonakala sikhula, leso yisibonakaliso esiyinhloko sesixwayiso.

Ezigabeni zakamuva, ungase ubhekane nalokhu:

• Ukukhathala okuqhubekayo, okungachazeki
• Ukwehlisa isisindo okungachazeki
• Ukujuluka ebusuku

Yini ebangela i-Clear Cell Sarcoma?

Imbangela eqondile iyinkimbinkimbi. Ucwaningo lwezokwelapha lukhombisile ukuthi i-Clear Cell Sarcoma ibangelwa yiphutha lezakhi zofuzo lapho izingxenye zama -chromosome amabili zishintshana khona, okuholela ku- fuzed gene .

Empeleni, ngesikhathi sokuhlukaniswa kwamaseli, ama-chromosome angaphuka futhi ashintshanise izingxenye. Ngokukhethekile, izingxenye eziqukethe izakhi zofuzo ze -EWSR1 kanye ne-ATF1 ziyashintshwa. Izakhi zofuzo ze-EWSR1 zivame ukubandakanyeka ekulawulweni kwamaseli, kuyilapho i-ATF1 isiza ukulawula ukukhula kwamaseli. Lapho la ma-chromosome ephinde anamathele, izinto zofuzo ezihlanganisiwe zifakwa ngendlela engafanele. Odokotela babhekisela kulokhu njengokudluliselwa okuhambisanayo . Kungani leli phutha lenzeka ngokuzenzakalelayo kuseyisihloko socwaningo lwesayensi oluqhubekayo.

Uma lokhu kushintshela ku-chromosome entsha kwenzeka, izakhi zofuzo ezihlelwe kabusha ziyahlangana zakhe i -fuse gene eyaziwa ngokuthi i-EWSR1/ATF1 . Abacwaningi bakholelwa ukuthi le jini ethile ehlanganisiwe iyona ebangela ukuthuthukiswa kwe-clear cell sarcoma.

Odokotela bakuthola kanjani i-clear cell sarcoma?

Uma uvakashela udokotela wakho uneqhubu elibonakalayo, bazokwenza ukuhlolwa ngokomzimba ukuze bahlole indawo yalo, usayizi, kanye nezici zalo. Bangase futhi bacele ukuhlolwa kwe-MRI (Magnetic Resonance Imaging) ukuze bathole ukubukeka okuningiliziwe.

Kodwa-ke, ukuxilongwa okunembile kwe-clear cell sarcoma kuqinisekiswa nge-biopsy , lapho kuthathwa khona isampula encane yezicubu eqhubu. Ochwepheshe bezifo—ochwepheshe abahlola izicubu elabhorethri—bazohlaziya lesi sampula ngaphansi kwe-microscope befuna ngqo i- EWSR1/ATF1 fused gene esikhulume ngayo ekuqaleni.

Iphathwa kanjani i-clear cell sarcoma?

Umgomo oyinhloko wethimba lakho lezokwelapha ukuvimbela umdlavuza ukuthi ungasabalali kwezinye izingxenye zomzimba wakho. Ngokuvamile, isinyathelo sokuqala ukususa isimila sonke ngokuhlinzwa . Uma kukhona ubufakazi bokuthi umdlavuza usufinyelele kuma-lymph node aseduze, nawo azosuswa. Lokhu kuvame ukulandelwa ukwelashwa okungeziwe , okuvame kakhulu ukwelashwa ngemisebe , ukubhubhisa noma yimaphi amangqamuzana omdlavuza asele.

Abacwaningi eNirogi Lanka nakwamanye amazwe bahlola ngenkuthalo izindlela ezintsha zokwelapha. Isibonelo, bahlola ukusebenza kahle kwe -immunotherapyekuphatheni i-clear cell sarcoma. Ngaphezu kwalokho, izivivinyo zemitholampilo ziphenya ukuthi imithi esetshenziswa njengamanje kwezinye izinhlobo zomdlavuza ingasiza yini ekumiseni ukuqhubeka kwalesi simo.

Kubalulekile ukuqonda ukuthi i-clear cell sarcoma ivame ukuphinda ibuye. Uma lokhu kwenzeka, kungase kudingeke ukuhlinzwa okwengeziwe noma ukwelashwa ngemisebe. Ngenxa yokuthi lolu hlobo lomdlavuza lungasakazeka ngokushesha, odokotela bakho bazohlela ukuvakasha okulandela njalo ukuze bakuqaphe eduze noma yikuphi ukukhula kwesimila esisha.

Ngingayinciphisa yini ingozi yami yokuthola i-clear cell sarcoma?

Ngeshwa, ayikho indlela eyaziwayo yokunciphisa ingozi yokuthola lesi simo. Njengamanje, abacwaningi abakwazanga ukuhlonza izici ezithile eziyingozi —imikhuba noma izimo ezandisa amathuba okuthola lesi sifo—ze-clear cell sarcoma.

Ingabe i-clear cell sarcoma ingalapheka ngokuphelele?

Nakuba odokotela bengelapha i-clear cell sarcoma ngokususa izimila nokulawula ukusabalala kwazo, okwamanje akubhekwe njengesimo esingelapheka ngokuphelele . Ngokuvamile, ngesikhathi umdlavuza utholakala, kungenzeka ukuthi usuvele usakazekele kwezinye izingxenye zomzimba, okwenza ukwelashwa kube nzima kakhulu. Ngaphezu kwalokho, amathuba aphezulu okuphinda ubuye asalokhu eyinkinga enkulu.

Iyini isikhathi sokuphila komuntu one-clear cell sarcoma?

Isikhathi sokuphila siyisilinganiso esijwayelekile esisekelwe kudatha yabantu, uma ucabangela impilo yakho iyonke kanye nezimo zomuntu ngamunye. Ukubuyekezwa kuka-2018 yi-US National Cancer Database kubonise ukuthi ama-50% abantu abatholakale benesifo se-clear cell sarcoma babesaphila ngemva kweminyaka emihlanu , kanti ama-38% ayesaphila ngemva kweminyaka eyishumi .

Nakuba sixoxa ngezibalo zokusinda, kubalulekile ukukhumbula ukuthi lezi ziyizilinganiso nje, hhayi izibikezelo zesimo sakho esithile. Amazinga okusinda asekelwe emaqenjini amakhulu abantu; izici eziningi zithonya umphumela womuntu ngamunye. Uma utholakale une-clear cell sarcoma, udokotela wakho ungumthombo ongcono kakhulu wolwazi mayelana nokubikezela kwakho kanye nokulindela.

Ingabe i-clear cell sarcoma ingaba yingozi?

Yebo, kungaba yingozi. Ngokuvamile, abantu abanomdlavuza osakazekele kwezinye izingxenye zomzimba babhekene nengozi enkulu kunalabo abathola ukwelashwa ngaphambi kokuba umdlavuza usabalale.

Kufanele ngimbone nini udokotela wami?

Njengoba i-Clear Cell Sarcoma isengozini yokuphinda ivele ngisho nangemva kokwelashwa, udokotela wakho angadinga ukuthi uvakashele i-Clear Cell Sarcoma njalo ezinyangeni ezintathu phakathi neminyaka emibili yokuqala ngemva kokwelashwa kwakho kokuqala, kuye ngesimo sakho esithile. Kubalulekile ukuthi uqhubeke nalezi zikhathi zokuhlolwa ezihleliwe ngisho nangemva kwaleso sikhathi.

Yimiphi imibuzo okufanele ngiyibuze udokotela wami?

I-Clear Cell Sarcoma yisimo esingavamile kakhulu esingasongela impilo. Uma uke watholakala unalesi simo, nansi eminye imibuzo ongase ufune ukuyibuza umhlinzeki wakho wezempilo:

• Ikuphi ithumba, futhi lingakanani ubukhulu balo?
• Ingabe lesi simila sisakazekele kwezinye izingxenye zomzimba wami?
• Yiluphi uhlelo lokwelashwa olungincomayo?
• Yimiphi imiphumela emibi engaba khona ngenxa yokwelashwa okunconywayo?
• Uma ngihlinzwa, ingakanani ingozi yokuthi isimila sibuye?
• Ingabe kukhona ukuhlolwa kwemitholampilo okufanele ngikucabangele?

Isifinyezo kanye nomyalezo wokuthatha uye ekhaya

I-Clear Cell Sarcoma iyisifo esiyinselele nesingavamile esithinta abantu abambalwa kakhulu minyaka yonke. Sivame ukukhula kancane, okungaholela esimweni lapho umdlavuza usuvele usakazeke khona ngesikhathi ubona noma yiziphi izinguquko zomzimba.

Kodwa-ke, sicela ukhumbule ukuthi ochwepheshe bezokwelapha basungule izindlela zokuphatha nokwelapha i-Clear Cell Sarcoma, ngokuvamile ehilela ukuhlinzwa ukuze kususwe isimila kulandelwe ukwelashwa okusizayo ukuze kuqedwe amangqamuzana omdlavuza asele. Ngeshwa, kunengozi yokuphinda kwenzeke. Ngakho-ke, ukuya emihlanganweni yakho yokulandelela nokuhlala uqaphile mayelana nanoma yiziphi izinguquko emzimbeni wakho kubaluleke kakhulu.

Abacwaningi basebenza njalo ukuthuthukisa izindlela zokwelapha ezintsha nezithuthukisiwe. Uma kutholakale ukuthi une-Clear Cell Sarcoma futhi unesifiso sokufunda ngezivivinyo ezintsha zemitholampilo , sicela uxhumane nodokotela wakho ukuze uthole isiqondiso. Ungalokothi ulahle ithemba.Ngeseluleko esifanele sezokwelapha, ukwesekwa kochwepheshe, kanye nendlela yokubhekana nesimo esiphuthumayo, ungabhekana nale nselele ngempumelelo. Uma ubhekene nesimo esiphuthumayo, sicela uxhumane no-911 noma uvakashele umnyango wezimo eziphuthumayo oseduze nawe ngokushesha.

I-Nirogi Lanka: i-clear cell sarcoma, umdlavuza wezicubu ezithambile, amaqhubu emilenzeni, amaqhubu ezinyawo, i-sarcoma, izimpawu zomdlavuza, ukwelashwa komdlavuza