Ngezinye izikhathi thina noma othandekayo kufanele sithole ukwelashwa okukhulu njengokufakelwa i-stem cell ngenxa yesifo esibi njengomdlavuza. Ngisho noma ukwelashwa okunjalo kuphumelela, ngezinye izikhathi kungabangela izinkinga ezithile. Namuhla sikhuluma ngomuthi okhethekile onikezwa ukwelapha inkinga enkulu kangaka, kodwa engavamile. Lowo muthi wokugoma obizwa ngokuthi i-Defibrotide.
Iyini i-Defibrotide futhi isetshenziselwani?
Kalula nje, i-Defibrotide iwumjovo okhethekile. Isetshenziselwa ukwelapha isimo esibucayi esenzeka ngemva kokufakelwa iseli le-stem, ngenxa yokuvaleka kwemithambo yegazi emincane kakhulu esibindini . Ngokwezokwelapha, lesi simo sibizwa ngokuthi i-Veno-occlusive Disease (VOD) noma i-Sinusoidal Obstruction Syndrome (SOS).
Ake sithi kunemithambo yegazi emincane egeleza esibindini sethu. Ngemva kokwelashwa okukhulu njengokufakelwa i-stem cell, ngezinye izikhathi le mithambo yegazi ingavimbeka. Lokhu kungaba nomthelela omkhulu ekusebenzeni kwesibindi. Ngaleso sikhathi, umuthi obizwa ngokuthi i-Defibrotide usiza ukuvula kabusha le mithambo yegazi evinjiwe futhi unciphise umonakalo esibindini.
Into ebalulekile ukuthi, lo muthi awusiwo umuthi ongawuthatha ekhaya. Unikezwa njengomuthi esibhedlela, ngaphansi kokuqondisa okugcwele kodokotela nabahlengikazi .
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala ukwelashwa
Ngaphambi kokuba wena noma isiguli sakho niqale ukwelashwa nge-Defibrotide, kubaluleke kakhulu ukutshela udokotela wakho ngomlando wakho wezempilo ophelele. Ikakhulukazi, kufanele uqaphele lezi zimo ezilandelayo:
| Isimo okudingeka usibike | Kungani kunjalo? |
|---|---|
| Uma unesifo sokopha. | Lokhu kubaluleke kakhulu uma usuvele unesifo, njengoba i-defibrotide ingandisa ingozi yokopha. |
| Uma uthatha eminye imithi enciphisa igazi noma evimbela ukujiya kwegazi (imithi yokunciphisa igazi). | Udokotela kufanele aqaphele lokhu, njengoba ukusebenzisa le mithi ndawonye kungabangela ukopha okukhulu. |
| Uma une-allergy ku-Defibrotide noma kunoma yimuphi omunye umuthi, ukudla, noma idayi. | Lokhu kubalulekile ukuvimbela ukusabela kwe-allergy. |
| Uma ukhulelwe, uzama ukukhulelwa, noma uncelisa. | Kufanele uxoxe nodokotela wakho ngokuthi lo muthi uzomthinta kanjani umama nengane. |
Imithi okungafanele isetshenziswe ne-Defibrotide
Isexwayiso: Uma uthatha i-Defibrotide, eminye imithi evimbela ukujiya kwegazi noma ukunciphisa igazi, njenge -Heparin ne-Alteplase , ingabangela ukopha okukhulu . Ngakho-ke, qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyithathayo, okuhlanganisa imithi yamakhambi, amavithamini, kanye nezithasiselo.
Imiphumela emibi engaba khona
Njenganoma yimuphi umuthi, i-Defibrotide ingabangela imiphumela emibi. Eminye yale miphumela ingaba mibi kakhulu, ngakho-ke kubalulekile ukuzazi futhi wazise ithimba lakho lezokwelapha ngokushesha uma uhlangabezana nanoma yiziphi izimpawu.
| Umphumela ongemuhle | Incazelo |
|---|---|
| Uma unalezi zimpawu, tshela udokotela wakho noma umhlengikazi ngokushesha. | |
| Ukusabela Kokungezwani Nomzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe noma ulimi. |
| Izimpawu Zokopha | Igazi elisesihlahleni noma esihlahleni esimnyama, umchamo obomvu noma onsundu omnyama, ukuhlanza into ebukeka njengekhofi eligayiwe, amabala abomvu esikhumbeni, ukuphuma kwegazi okungavamile emehlweni, ezinsinini, noma ekhaleni. |
| Izimpawu Zomfutho Wegazi Ophansi | Ukuzungeza, ukubona okufiphele, ukuquleka, ukuzizwa ukhathele noma ubuthakathaka ngendlela engavamile. |
| Izimpawu Zokutheleleka | Umkhuhlane noma ukuzizwa ubanda, ukukhwehlela, umphimbo obuhlungu. |
| Lokhu ngokuvamile akukubi kangako, kodwa uma kuqhubeka, tshela udokotela wakho. | |
| Uhudo | Ukuqunjelwa. |
| Isicanucanu | Ukuzizwa sengathi uhlanza. |
| Ukuhlanza | Ukuhlanza. |
Yini okufanele uyenze uma umthamo ukhuphuka (ukudlula umthamo)?
Njengoba lo muthi unikezwa esibhedlela, ngaphansi kokuqashwa kwezokwelapha, ngenani elinembile kakhulu, amathuba okudlula ngokweqile aphansi kakhulu. Ithimba lezokwelapha lihlala likhathazekile ngakho. Kodwa uma kukhona ukusola ngento enjalo, udokotela noma umhlengikazi esibhedlela uzothatha izinyathelo ezidingekayo. Ngokuvamile, indawo esemthethweni yokuthola iseluleko ezweni lakithi uma kwenzeka ubuthi yiNational Poisons Information Centre eColombo National Hospital . Kodwa uma kwenzeka into efana nale esibhedlela, i-Emergency Treatment Unit (ETU) yesibhedlela iyavulwa ngokushesha.
Umlayezo Wokuya Nawe Ekhaya
- I-Defibrotide iwumjovo okhethekile onikezwa emthanjeni olapha izinkinga ezinkulu zesibindi ezingase zenzeke ngemva kokufakelwa iseli le-stem.
- Kubalulekile ukutshela udokotela wakho ngayo yonke eminye imithi oyithathayo, ikakhulukazi imithi yokunciphisa igazi, kanye nanoma yiziphi izimo zezokwelapha onazo.
- Ingozi enkulu phakathi nalokhu kwelashwa ukopha . Ngakho-ke, uma ubona ngisho nophawu oluncane lokopha, yazisa ithimba lezokwelapha ngokushesha.
- Lo muthi unikezwa esibhedlela kuphela futhi awuwona umuthi wokusetshenziswa ekhaya.
- Uma unemibuzo noma ukukhathazeka mayelana nalo muthi noma ukwelashwa, sicela ungangabazi ukubuza udokotela wakho noma abasebenzi bobuhlengikazi.
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