Ingabe indlala yakho ye-pituitary "ayinalutho"? Ake sifunde nge-Empty Sella Syndrome (ESS)!

Ingabe ngezinye izikhathi uphathwa yikhanda ngaso sonke isikhathi? Noma ucabanga ukuthi kuhlobene nama-hormone? Uma udokotela ethi kudingeka enze i-"(CT)`` scan yekhanda lakho noma i-"(MRI)`` scan, bangase bathole ukuthi indawo lapho i-pituitary gland yakho itholakala khona ibukeka "ingenalutho." Yilokho esikubiza ngokuthi i-Empty Sell. Kodwa ingabe kuyinkinga enkulu njalo? Ake sixoxe ngalokhu ngokuningiliziwe.

Iyini i-Empty Sella Syndrome (ESS)?

Kalula nje, i-Empty Sella Syndrome (ESS) iyisimo esingavamile kakhulu. Kwenzeka lapho i-pituitary gland yakho – i-gland encane kodwa ebaluleke kakhulu etholakala phansi kobuchopho bakho – iba yindlala noma ishwabene endaweni yayo, umgodi onamathambo obizwa ngokuthi i-sella turcica . Cabanga ngale ndlela, i-sella turcica ifana nendlu encane evikela i-pituitary gland. Ngesizathu esithile, le 'ndlu' ingaba nkulu kakhulu, okubangela ukuba i-pituitary gland ikhukhumale futhi ibe ncane.

Igama elithi 'sella turcica' livela kwelesiLatini, elisho 'isihlalo saseTurkey'. Libizwa kanjalo ngoba lifana nesimo sesihlalo sehhashi. Abanye abantu abane-ESS bangathola izimpawu ezifana nokungalingani kwamahomoni , ikhanda elibuhlungu njalo, kanye nokushintsha kombono .

Ubuwazi ukuthi i-pituitary gland iyingxenye ebaluleke kakhulu ohlelweni lwethu lwe-endocrine , oluyisistimu ekhiqiza ama-hormone. Ikhiqiza ama-hormone amaningi abalulekile emizimbeni yethu. La ma-hormone alawula ezinye izindlala emizimbeni yethu.

Uyini umehluko phakathi kwe-Empty Sella ne-Empty Sella Syndrome?

Lokhu kuyadida kancane, ngakho lalela ngokucophelela. Nakuba amagama athi 'iseli elingenalutho' kanye 'ne-empty cell syndrome' ngezinye izikhathi asetshenziswa ngokushintshana, kunomehluko omncane. Ngamafuphi, iseli elingenalutho liwukuthola kwe-radiological , kanti i-empty cell syndrome iyisimo sezokwelapha.

'I-Empty Sella' yilapho i-pituitary gland yakho ibonakala ithambile noma inciphile ngesikhathi sokuskena. Kulesi simo, odokotela abakwazi ukubona i-pituitary gland kahle ngesikhathi sokuskena. Ngakho-ke, isikhala lapho i-pituitary gland ikhona khona, esibizwa ngokuthi i-sella turcica, sibukeka 'singenalutho'. Yilapho igama elithi 'empty sella' livela khona.

Kodwa-ke, i-sella turcica empeleni ayinalutho. Isikhathi esiningi, igcwele uketshezi lwe-cerebrospinal (CSF) . Le CSF uketshezi oluzungeza futhi luvikele ubuchopho bethu kanye nomgogodla. Esimweni 'sella engenalutho', lolu ketshezi lwe-CSF luvuza lungene ku-sella turcica futhi lubeka ingcindezi ku-pituitary gland. Lokho kucindezela kubangela ukuthi i-gland inciphe noma ibe buthaka.

Esikhathini esiningi, odokotela bathola leli 'seli elingenalutho' ngengozi. Okusho ukuthi, lapho benza i-``(CT)`` scan noma i-``(MRI)`` scan yekhanda ngesizathu esithile.

Ngisho noma abanye abantu benamaseli angenalutho kuma-scan abo, bangase bangabi nazimpawu futhi i-pituitary gland yabo ingasebenza kahle.

Kodwa-ke, uma umuntu ene-'empty sella' futhi i-pituitary gland yakhe ingasebenzi kahle, yilokho esikubiza ngokuthi i-Empty Sella Syndrome (ESS) . I -syndrome iqoqo lezimpawu ezihlobene. Abantu abane-ESS bangathola izinto ezifana nokungalingani kwama-hormone, izinguquko zombono, kanye nekhanda elibuhlungu njalo.

Kunezinhlobo ezimbili ze-Empty Sella, akunjalo?

Yebo, uma iskeni sakho sithola 'iseli elingenalutho', odokotela balihlukanisa ngezinhlobo ezimbili: eyokuqala neyesibili.

• I-Primary Empty Sella (PES): Yilapho odokotela bengakwazi ukuthola imbangela ecacile yokuthi i-pituitary gland yakho ibe yi-flat. Ezimweni eziningi, i-primary empty sella ayibangeli i-empty sella syndrome. Lokhu kusho ukuthi akuvamile ukubangela izimpawu.
• Ukuthengiswa Okungenalutho Kwesibili (i-SES): Lokhu kubangelwa esinye isimo esibonakalayo esithinta isakhiwo se-pituitary gland yakho noma i-sella turcica. Kalula nje, kubangelwa umonakalo ovela kwesinye isifo noma isenzakalo. Ezimweni ze-secondary empty sella (i-SES), i-empty sella syndrome inamathuba amaningi okukhula kunasezimweni ze-primary empty sella (i-PES).

Ingabe lokhu kusongela impilo ngenxa ye-Empty Sella Syndrome (ESS)?

Cha, i-Empty Sella Syndrome (ESS) ayisona isimo esisongela ukuphila. Ingelashwa ngemithi yama-hormone futhi ngezinye izikhathi ngokuhlinzwa.

Futhi, ukuthi nje ukuskena kobuchopho bakho kuthi 'iseli elingenalutho' akusho ukuthi kusongela impilo. Ezimweni eziningi 'zeseli elingenalutho', azikho izimpawu noma i-empty cell syndrome.

Iyini indima ye-Pituitary Gland?

I-pituitary gland iyi-endocrine gland ebaluleke kakhulu emzimbeni wethu. Ikhiqiza ama-hormone amaningi ahlukene. Iphinde itshele ezinye izindlala ohlelweni lwethu lwe-endocrine ukuthi zikhiphe ama-hormone. Okungukuthi:

• Izindlala ze-adrenal
• Amaqanda (kwabesifazane) noma amasende (kwabesilisa)
• Indlala yegilo

Ama-hormone afana nezithunywa zamakhemikhali. Ahamba egazini futhi athwale imiyalezo ezithweni zethu zomzimba, emisipheni, nakwezinye izicubu. Le miyalezo itshela umzimba ukuthi wenzeni nokuthi ukwenze nini.

I-pituitary gland ixhunywe ne-hypothalamus ebuchosheni bethu.Ixhunywe yisiqu esenziwe ngemithambo yegazi nemizwa. Lokhu kubizwa ngokuthi isiqu se-pituitary. Kungalesi siqu lapho i-hypothalamus ikhuluma khona ne-pituitary gland ithi, 'Kulungile, manje khipha la ma-hormone.' I-hypothalamus yingxenye yobuchopho bethu elawula izinto ezifana nomfutho wegazi, ukushaya kwenhliziyo, izinga lokushisa komzimba, kanye nokugaya ukudla.

I-pituitary gland ikhiqiza kakhulu ama-hormone alandelayo:

• I-hormone ye-Adrenocorticotropic (ACTH): Lokhu kukhuthaza izindlala ze-adrenal ukuthi zikhiqize ama-hormone (isb. i-cortisol) asabela ekucindezelekeni.
• I-hormone yokulwa nokukhipha isisu (i-ADH noma i-vasopressin): Ilawula ibhalansi yamanzi emzimbeni.
• I-Follicle-stimulating hormone (FSH): Isiza ukuvuthwa kwamaqanda kwabesifazane futhi ikhiqize isidoda kwabesilisa.
• I-hormone yokukhula (GH): Isiza imizimba yethu ikhule kusukela ebuntwaneni iye ebudaleni, ikakhulukazi emathanjeni nasemisipheni.
• I-Luteinizing hormone (LH): Isebenza ne-FSH ukusiza uhlelo lokuzala lusebenze. Ibalulekile ekukhiqizeni amaqanda kwabesifazane nasekukhiqizweni kwe-testosterone kwabesilisa.
• I-Oxytocin: Isiza isibeletho ukuthi sinciphe ngesikhathi sokubeletha kanye nokwehlisa ubisi ngesikhathi sokuncelisa.
• I-Prolactin: Ikhuthaza ukukhiqizwa kobisi lwebele.
• I-hormone evuselela i-thyroid (TSH): Itshela i-thyroid gland entanyeni ukuthi yenze ama-hormone e-thyroid. Lawa ma-hormone e-thyroid alawula izinga umzimba wethu osebenzisa ngalo amandla (i-metabolism).

Akuwona wonke la ma-hormone akhiqizwa njalo. Iningi lawo likhishwa ngokuqhuma, cishe njalo ngemva kwehora elilodwa kuya kwamathathu.

Ubani othinteka kakhulu yi-Empty Sella Syndrome (ESS)?

Nakuba lesi kuyisimo esingavamile, kokubili izingane kanye nabantu abadala bangaba ne-empty sella syndrome (ESS).

Kodwa-ke, iseli elingenalutho eliyinhloko (i-PES) – okusho ukuthi elibonakala kuphela kuskeni ngaphandle kwezimpawu – livame ngokuphindwe kane kwabesifazane kunakwabesilisa.

I-PES ivame kakhulu kubantu abaneminyaka ephakathi kuka-30 no-40. Ngezinye izikhathi ingenzeka kusenesikhathi kwabesifazane kunakwabesilisa. Abesifazane abakhulelwe isikhathi esigcwele basengozini enkulu yokuthola i-PES.

I-PES ayivamile ezinganeni kunakwabantu abadala. Uma kwenzeka, ivame ukuhlotshaniswa nezinye izimo zezokwelapha, njenge-Turner syndrome, isifo seMoyamoya, kanye ne-Prader-Willi syndrome.

Kuvamile kangakanani lokhu?

I-Empty Sella Syndrome (ESS) ayivamile kakhulu. Abanye abacwaningi balinganisela ukuthi abantu abangaphansi kuka-1% abane-'empty sella' bahlakulela izimpawu (okungukuthi, bahlakulela i-ESS).

Kodwa-ke, ukuba ne-sella engenalutho ngaphandle kwezimpawu kuvame kakhulu. Eminye imibiko iphakamisa ukuthi phakathi kuka-8% no-35% wabantu bangase babe ne-sella engenalutho. Eminye imibiko iphakamisa ukuthi cishe abantu abangu-12% bane-sella engenalutho, ngokusekelwe emiphumeleni yokuskena ubuchopho.

Ziyini izimpawu ze-Empty Sella Syndrome (ESS)?

Uphawu oluyinhloko oluhambisana ne-empty sella syndrome (ESS) yizinhlungu zekhanda ezingapheli. Kodwa-ke, abacwaningi abakaqiniseki ukuthi lezi zinhlungu zekhanda zibangelwa yi-ESS noma ukuthi zivele nje ngengozi. Lokhu kungenxa yokuthi abantu abaningi abane-ESS nabo banomfutho wegazi ophakeme (umfutho wegazi ophakeme), okungase kubangele nezinhlungu zekhanda uma ziba zimbi kakhulu.

I-ESS ivame ukubangela ukungalingani kwamahomoni ngenxa yomonakalo we-pituitary gland. Abantu abane-ESS bangase babe nezimpawu ezahlukene kuye ngomonakalo we-pituitary gland yabo kanye namahomoni athintekile. Uma une-ESS, ungase ube nezinye zezimpawu ezilandelayo:

• Ukuphuma koketshezi olungenabisi emabeleni (i-galactorrhea) (lokhu kungenzeka nakwabesilisa)
• Ukungasebenzi kahle kwe-Erectile ( kwabesilisa)
• Ukuya esikhathini okungajwayelekile noma ukungabikho kokuya esikhathini ngokuphelele (i-amenorrhea) (kwabesifazane)
• Ukuncipha noma ukuphelelwa yisifiso sobulili (isifiso esiphansi sobulili)
• Ukuzizwa ukhathele ngaso sonke isikhathi (Ukukhathala)

Akuvamile kakhulu, abanye abantu abane-ESS bangase babe nezimpawu ezifana nalezi:

• Ukwanda kwengcindezi ngaphakathi kwekhanda (ukucindezeleka okungekuhle kwangaphakathi kwekhanda)
• I-cerebrospinal rhinorrhea (ukuvuza kwe-CSF kusuka ekhaleni)
• Ukuvuvukala kwediski ye-optic ngaphakathi kweso (i-papilledema) ngenxa yokucindezela okukhulu ekhanda
• Ukushintsha kombono, isibonelo, ukubona okufiphele.

Futhi, ungaba 'neseli elingenalutho' ekuhlolweni kobuchopho, kodwa ungase ungabi nazimpawu. Eqinisweni, abantu abaningi abanamaseli angenalutho abanazo izimpawu futhi abasoze baba nazo.

Ingabe i-Empty Sella Syndrome (ESS) ibangela ukukhuluphala?

Uma i-pituitary gland yakho ingakhiqizi i-hormone evuselela i-thyroid (TSH) eyanele ngenxa ye-empty sella syndrome (ESS), kunethuba lokuthi uzokhuluphala.

I-TSH ivuselela indlala yegilo, etholakala ngaphambili entanyeni yakho, ngaphansi kwesikhumba, ukuze ikhiphe ama-hormone egilo. Umsebenzi oyinhloko wendlala yegilo ukukhiqiza ama-hormone egilo, alawula izinga lokuguqula ukudla okudlayo kube amandla, noma izinga lakho lokugaya ukudla .

Uma i-pituitary gland yakho ingakhiqizi i-TSH eyanele ngenxa ye-ESS, i-thyroid gland yakho ingase ingakhiqizi ama-hormone e-thyroid anele. Lokhu kungabangela ukuthi i-metabolism yakho yehle ngenxa yamazinga aphansi ama-hormone e-thyroid, okungaholela ekukhuleni kwesisindo.

Yini ebangela i-Empty Sella Syndrome (ESS)?

I-Empty Sella Syndrome (ESS) ingabangelwa yi-primary empty sella (PES) noma i-secondary empty sella (SES). Kodwa-ke, i-secondary empty sella (SES) cishe ingabangela i-ESS.

Izimbangela ze-Primary Empty Sella Syndrome (PES)

I-Primary esophagitis (PES) yenzeka lapho olunye ulwelwesi olumboza ingaphandle lobuchopho bakho (ungqimba lwe-arachnoid), i-sella turcica, luvuvukala ngaphakathi, lucindezela indlala ye-pituitary.

Odokotela abakakwazi ukuthola imbangela eqondile ye-primary empty sella syndrome.

Enye inkolelo-mbono ukuthi ubuthakathaka bokuzalwa esicutshini esimboze ubuchopho buvumela uketshezi lwe-cerebrospinal (CSF) ukuthi lungene ku-sella turcica, lubambe i-pituitary gland. Ezimweni ezinjalo, i-pituitary gland ivame ukuba nzima ukuyibona ku-scan, kodwa ivame ukusebenza kahle, ngakho-ke i-empty sella syndrome ayiveli.

Izimbangela Zokungasebenzi Kahle Kwesidoda Esincane (i-SES)

I-Secondary empty sella (SES) yenzeka lapho i-pituitary gland yakho noma i-sella turcica yonakaliswa esinye isifo noma isenzakalo. Ngakho-ke, kunezimbangela eziningi ezingaba khona ze-SES. Ngokuvamile, izimbangela eziyinhloko zalo monakalo yilezi:

• Isimila sobuchopho .
• Ukwelashwa ngemisebe .
• Ukuhlinzwa kobuchopho kwenziwe endaweni ezungeze indlala ye-pituitary.
• Ukulimala okukhulu ekhanda, isibonelo ukulimala kobuchopho okubuhlungu.

Nazi ezinye izimbangela ezithile ezingathinta ukuphuma kwesibili kwesinye:

• Izimila zobuchopho: Ngezinye izikhathi izimila zobuchopho zingabangela ingcindezi eyengeziwe ezungeze ubuchopho bakho (ingcindezi yangaphakathi kwekhanda), engacindezela indlala ye-pituitary.
• I-Idiopathic intracranial hypertension (IIH): IIH ukwanda kwengcindezi ngaphakathi kogebhezi ngenxa yokuqongelela koketshezi lomgogodla (CSF) oluzungeze ubuchopho bakho. Lokhu kucindezela ngokweqile kungacindezela indlala ye-pituitary.
• Ama-adenoma e-pituitary: Lawa amathumba akhula e-pituitary gland. Esikhathini esiningi, awawona umdlavuza (angabi yingozi). Lawa ma-adenoma angacindezela i-pituitary gland futhi ayilimaze.
• I-Sheehan's syndrome: Lesi yisimo esingase senzeke ngezinye izikhathi uma kukhona ukopha ngokweqile, okusongela ukuphila ngesikhathi sokubeletha. Lokhu kungabangela ukuthi umzimba untule umoya-mpilo futhi kulimaze indlala ye-pituitary.

Itholakala kanjani i-Empty Sella Syndrome (ESS)?

Esikhathini esiningi, odokotela bathola i-sella engenalutho ngengozi, lapho behlola ikhanda ngesinye isizathu. Futhi, abantu abaningi abane-sella engenalutho abakaze babe ne-empty sella syndrome noma babe nanoma yiziphi izimpawu.

Kodwa-ke, uma unezimpawu ezihlobene ne-empty cell syndrome, njengobuhlungu bekhanda obuvamile kanye nokungalingani kwama-hormone, udokotela wakho uzokubuza ngomlando wakho wezokwelapha, enze ukuhlolwa ngokomzimba, futhi cishe uzoyala ukuba kuhlolwe ikhanda kanye nobuchopho.

Ama-scan asetshenziselwa ukuxilonga i-ESS yile:

• I-CT scan yobuchopho (i-computed tomography): I-CT scan iyindlela yokuthatha izithombe ezicacile zobuchopho bakho kanye ne-pituitary gland usebenzisa i-X-ray kanye nekhompyutha.
• Ukuskena kobuchopho nge-magnetic resonance imaging (MRI): Ukuskena kwe-MRI kusebenzisa amaza omsakazo kanye nama-magnet aqinile ukwenza izithombe ezicacile zezingxenye ezingaphakathi komzimba wakho, njenge-sella turcica yakho.

Udokotela wakho angase futhi acele ukuhlolwa okwengeziwe, njengokuhlolwa kwegazi, ukuhlola amazinga akho ama-hormone.

Ngezinye izikhathi, odokotela bangase benze nokuhlolwa okufana nalokhu ukuhlola ingcindezi eyengeziwe ebuchosheni bakho:

• Cela udokotela wamehlo ukuthi ahlole i-retina engaphakathi kweso lakho.
• Ukubhoboza i-Lumbar (umpompi womgogodla) – Lokhu kulinganisa ingcindezi yoketshezi lomgogodla.

Yiziphi izindlela zokwelapha i-Empty Sella Syndrome (ESS)?

Ngisho noma amaskeni akho ebonisa 'iseli elingenalutho', uma indlala yakho ye-pituitary isebenza kahle, ngeke udinge ukwelashwa. Yilokhu okwenzekayo isikhathi esiningi.

Kodwa-ke, uma une-Empty Sella Syndrome (ESS) futhi i-pituitary gland yakho ingasebenzi kahle, ukwelashwa kuyimithi yokulungisa amazinga aphansi ama-hormone. Okusho ukuthi, umuthi unqunywa ngokusekelwe ekutheni iyiphi i-hormone ephansi.

Uma i-ESS ibangela ukuthi uketshezi lomgogodla (CSF) luphume ekhaleni lakho (CSF rhinorrhea), kungadingeka uhlinzwe ukuze kulungiswe i-sella turcica yakho.

Yiziphi izici eziyingozi ze-Empty Sella Syndrome (ESS)?

Odokotela abaqiniseki ukuthi yini ngempela ebangela i-empty sella syndrome kwabanye abantu abane-empty sella. Kodwa-ke, i-empty sella syndrome inamathuba amaningi okukhula nge-secondary empty sella (SES) kune-primary empty sella (PES). Lokhu kusho ukuthi uma i-empty sella ibangelwa okunye, njengesimila sobuchopho, ukwelashwa ngemisebe, noma ukulimala ekhanda, kungenzeka kakhulu ukuthi ube nezimpawu.

Kuyini ukubikezela kokugula komuntu one-Empty Sella Syndrome (ESS)?

Umbono womuntu one-empty sella syndrome (ESS) ngokuvamile muhle. Kunemithi yokwelapha ukungalingani kwama-hormone. Uma une-hormonal imbalance ngenxa ye-ESS, kungadingeka ukuthi uthathe imithi impilo yakho yonke.

Kufanele ubonane nini nodokotela uma une-empty cell syndrome?

Uma kutholakale ukuthi une-Empty Sella Syndrome (ESS), futhi uba nezimpawu ezintsha noma uma izimpawu zakho ezikhona ziba zimbi kakhulu, bona udokotela wakho ngokushesha.

Uma uphuza imithi yokungalingani kwama-hormone ngenxa ye-empty stomach syndrome, kubaluleke kakhulu ukubona udokotela wakho njalo ukuqinisekisa ukuthi imithi yakho isebenza kahle.

Ngakho-ke, yini okufanele siyikhumbule kulokhu?

Nokho, i-Empty Sella Syndrome (ESS) empeleni iyisimo esingavamile kakhulu. Kodwa-ke, kuvamile ukuthola ukuthi unento ebizwa ngokuthi 'iseli elingenalutho' ekuhlolweni kobuchopho. Ngakho-ke ungakhathazeki ngoba nje udokotela esho kanjalo. Esikhathini esiningi, abantu abane-'empty cell' abanazo izimpawu futhi abanazo izimpawu ze-Empty Sella Syndrome.

Uma unemibuzo mayelana nombiko wakho wokuskena, ungesabi ukubuza udokotela wakho. Bakhona ukukusiza. Ukunakekela impilo yakho kuyinto ebaluleke kakhulu.

I- Empty Sella Syndrome, i-Pituitary gland, ama-hormone, ukuskena kobuchopho, i-Sellae Tursica