Izinto okudingeka uzazi nge-Hydroxychloroquine

Kungenzeka ukuthi uke wezwa igama elithi Hydroxychloroquine ezindabeni ngesikhathi sobhubhane lwe-COVID. Kodwa empeleni umuthi omdala kakhulu oye wasetshenziswa kusukela ngawo-1940. Ezinsukwini zokuqala, odokotela babewusebenzisa ukwelapha umalaleveva. Namuhla, uvame ukusetshenziswa kakhulu kwezinye izimo zezokwelapha. Namuhla, sizoxoxa ngokuthi lo muthi usetshenziselwani ngempela, ukuthi ungadala miphi imiphumela emibi, nokuthi yini okufanele uyiqaphele lapho uwusebenzisa.

Ingabe lo muthi ufanelekile ngempela kwi-Covid-19?

Lona umbuzo abantu abaningi abanawo. Kalula nje, cha . I-World Health Organization (WHO) ayincomi i-hydroxychloroquine ekuvimbeleni noma ekwelapheni i-COVID-19. Bafinyelele kulesi sinqumo ngemuva kocwaningo olunzulu.

Cabanga nje, izifundo eziyi-6 zabantu abayizinkulungwane abangenayo i-COVID-19 zithole ukuthi umuthi awunawo umthelela ekuvimbeleni ukuthi bathole i-COVID, bangene esibhedlela, noma bafe. Futhi izifundo ezingama-30 zeziguli ezingaphezu kuka-10,000 ze-COVID-19 zithole ukuthi umuthi awuzange unciphise isidingo sama-ventilator noma ingozi yokufa. Yingakho unganconywa njengamanje nge-COVID-19.

Ngakho-ke lo muthi usetshenziselwa izifo ezinjani?

I-Hydroxychloroquine isetshenziswa kakhulu namuhla ezifweni zokuzivikela komzimba. Manje kungenzeka ukuthi uyazibuza ukuthi iyini leyo.

Kalula nje, lokhu kwenzeka lapho uhlelo lokuzivikela lomzimba wethu, uhlelo lokuzivikela, luhlasela ngephutha amangqamuzana nezicubu zethu ezinempilo. Lokhu kubangela ukuvuvukala nomonakalo emalungeni, emisipheni, futhi ngezinye izikhathi ezithweni zangaphakathi.

Udokotela wakho angakunikeza lo muthi uma unezinye zezimo ezilandelayo:

• Isifo samathambo esibizwa ngokuthi i-rheumatoid arthritis
• I-systemic lupus erythematosus (SLE)
• I-arthritis ye-idiopathic yentsha
• I-Antiphospholipid syndrome
• Isifo sikaSjogren esiyinhloko

Ochwepheshe abakaqiniseki ukuthi lo muthi usebenza kanjani ngempela, kodwa bacabanga ukuthi ushintsha indlela amasosha omzimba abonisana ngayo. Kungase futhi kucime ezinye zezinqubo ezibangela ukuvuvukala.

Yimiphi imiphumela emibi engaba khona yalo muthi?

Njenganoma yimuphi umuthi, i-hydroxychloroquine ingabangela imiphumela emibi. Nakuba kungebona bonke abantu abayitholayo, eminye imiphumela emibi ilula futhi iyanyamalala ngokuhamba kwesikhathi.

Ngaphezu kwalokho, ezinye izimpawu ezilandelayo zingase zivele:

• Ukuluma noma ukuqubuka esikhumbeni
• Ukufiphala noma ukufiphala kwesikhumba
• Izinguquko zezinwele (isb., ukushintsha kombala)
• Ubuthakathaka bemisipha
• Izinguquko zesimo sengqondo
• Ukukhala ezindlebeni

Imiphumela emibi kakhulu okufanele uyiqaphele

Lezi zinzima kancane, ngakho-ke kubaluleke kakhulu ukuqaphela lokhu.

Imiphumela enhliziyweni

I-Hydroxychloroquine ingabangela izinguquko eziyingozi esigqini senhliziyo. Lokhu kuyiqiniso ikakhulukazi uma uyithatha kanye neminye imithi ethile, njenge- azithromycin . Lokhu kungabangela izinguquko emsebenzini kagesi wenhliziyo. Ngokukhethekile, kungabangela ukushaya kwenhliziyo okusheshayo okungajwayelekile (i-ventricular tachycardia) noma ushintsho oluyingozi esigqini senhliziyo (isikhawu se-QT eside).

Ukulimala kwamehlo

Leli iphuzu elibaluleke kakhulu. Nakuba lingavamile, i-hydroxychloroquine ingadala umonakalo ku-retina yeso.

Ungakhohlwa ukuthi lo muthi ungalimaza amehlo akho. Kwezinye izimo, ungase ulahlekelwe ngisho nokubona unomphela.

Le ngozi iyanda kubantu abafana nalaba:

• Kulabo abaneminyaka engaphezu kwengu-60 ubudala
• Kulabo abathatha imithamo ephezulu yalo muthi iminyaka engaphezu kwemi-5
• Kulabo abanesifo esibi sezinso noma sesibindi
• Kulabo asebevele benesifo samehlo noma se-retina

Ngakho-ke, uma usebenzisa lo muthi isikhathi eside, kubalulekile ukuthi amehlo akho ahlolwe njalo ngudokotela wamehlo.Udokotela wakho uzokutshela ukuthi uhlolwe amehlo akho kanye ngonyaka noma okungenani kanye njalo eminyakeni emihlanu.

Eminye imiphumela emibi kakhulu

• Izinkinga zesistimu yegazi: I-anemia ingase ivele kaningi, ikakhulukazi kubantu abanezinkinga zegazi ezifana nokuntuleka kwe-G6PD noma i-porphyria.
• Izinkinga zezinso
• Ukulimala kwesibindi noma ukungasebenzi kahle kwaso

Ukusebenzisana Kwezidakamizwa

I-Hydroxychloroquine ingase ihlangane neminye imithi. Ingashintsha indlela esebenza kahle ngayo noma yandise ingozi yemiphumela emibi. Ngakho-ke kubalulekile ukutshela udokotela wakho nganoma yimiphi imithi, amavithamini, noma izithasiselo ozithathayo.

Uma uthatha i-tamoxifen yomdlavuza webele, khuluma nodokotela wakho ngalokho futhi. Kungase kungafaneleki ukuthatha le mithi emibili ndawonye isikhathi esingaphezu kwezinyanga eziyisithupha.

Ubani ongawuthatha lo muthi? Ubani ongakwazi?

I-Hydroxychloroquine iphephile kubantu abadala abaningi kanye nezingane. Udokotela wakho uzonquma umthamo ofanele ngokusekelwe esisindweni somzimba wakho.

Nakuba ucwaningo lukhombisile ukuthi lo muthi uphephile ukuwuthatha ngesikhathi sokukhulelwa noma ukuncelisa,Qiniseka ukuthi ukhuluma nodokotela wakho nganoma yimiphi imithi oyithathayo.

Uma une -psoriasis , isifo sesikhumba, qaphela lokho ngoba lo muthi ungase ube mubi kakhulu izimpawu zakho.

Ubani okungafanele athathe lo muthi?

Uma une-allergy kweminye imithi equkethe ama-compounds angu-4-aminoquinoline, njenge-chloroquine, akufanele uthathe i-hydroxychloroquine.

Uma uzwa izimpawu zokusabela kokungezwani komzimba, hamba ngokushesha esibhedlela esiphuthumayo (ETU). Izimpawu ezinjalo zifaka:

• Ukuvuvukala komphimbo, umlomo, noma ubuso
• Ukuqhuma kwesikhumba noma ukuqubuka
• ukulunywa okukhulu