Uma wena noma othile emndenini wakho enesifo sikaParkinson, cishe uyazi ukuthi sithinta kangakanani impilo yakho yansuku zonke. Ukuphila nokuthuthumela, ubunzima bokuhamba, nokuqina akulula. Odokotela banikeza imithi ehlukahlukene yokulawula lezi zimpawu. Namuhla sizokhuluma ngomunye wemithi enjalo, i-Istradefylline.
Kalula nje, iyini i-Istradefylline?
I-Istradefylline umuthi osiza ukulawula izimpawu zesifo sikaParkinson. Ngokuvamile ayinikezwa yodwa. Isetshenziswa
njengomuthi owengeziwe lapho umuntu osevele ethatha imithi esetshenziswa kakhulu yesifo sikaParkinson, iCarbidopa neLevodopa, engasebenzi kahle. Cabanga nje, udokotela wakho usevele ekunike iCarbidopa/Levodopa, kodwa ngokuhamba kwesikhathi, uzizwa sengathi inzuzo yomuthi ayanele, noma uzizwa sengathi isikhathi sokuphumula somuthi siyanda. Ngezikhathi ezinjalo, udokotela wakho unezela lo muthi we-Istradefylline ukusiza ukulawula izimpawu zakho kangcono. Lo muthi usebenza ngokulinganisela umsebenzi wamakhemikhali athile (ama-neurotransmitters) ebuchosheni bethu alawula ukunyakaza komzimba kanye nokuxhumana. Ngale ndlela, unganciphisa izimpawu eziyinhloko zesifo sikaParkinson, njengokuqina nokuthuthumela.
Izinto okudingeka uzitshele udokotela wakho ngaphambi kokuqala lo muthi
Ngaphambi kokuqala noma yimuphi umuthi, kubaluleke kakhulu ukunikeza udokotela wakho incazelo ephelele yesimo sakho sempilo. Ikakhulukazi ngaphambi kokuqala i-Istradefylline, qiniseka ukuthi utshela udokotela wakho uma unezinye zezimo ezilandelayo:
- Isifo sesibindi : Kubalulekile ukutshela udokotela wakho uma unesifo sesibindi, njengoba isibindi sidlala indima enkulu enqubweni yokususa lo muthi emzimbeni. Uma unenkinga yesibindi, imiphumela yomuthi inganda ngokungadingekile.
- Izimo zempilo yengqondo : Uma uke waba nokucindezeleka , ukukhathazeka , noma ezinye izimo zempilo yengqondo , yazisa udokotela wakho ngakho.
- Uma ubhema (Ukusebenzisa ugwayi): Uma ubhema, kufanele utshele nodokotela wakho ngakho. Lokhu kungenxa yokuthi ukubhema kunganciphisa ukusebenza kwalomuthi. Futhi, uma uhlela ukuyeka ukubhema, kufanele utshele nodokotela wakho ngakho, ngoba khona-ke umthamo womuthi kungadingeka ushintshwe.
- Ukungezwani komzimba: Sitshele uma une-allergies kulo muthi we-Istradefylline, noma yimuphi omunye umuthi, ukudla, noma udayi.
- Uma ukhulelwe noma uzama ukukhulelwa: Lokhu kubaluleke kakhulu. Uma ukhulelwe, uzama ukukhulelwa, noma usola ukuthi ukhulelwe, ungasebenzisi lo muthi. Qiniseka ukuthi ukhuluma nodokotela wakho ngalokhu.
- Uma ungumama oncelisayo: Uma ungumama oncelisayo, tshela udokotela wakho ngakho futhi.
Ngingawusebenzisa kanjani umuthi ngqo?
Into ebaluleke kakhulu ukusebenzisa umuthi njengoba nje udokotela esho.
- Thatha lo muthi nengilazi yamanzi.
- Zenze umkhuba ukuphuza imithi yakho ngesikhathi esifanayo nsuku zonke. Lokhu kuzosiza ukugcina imiphumela yomuthi isezingeni elifanayo emzimbeni wakho.
- Ungakuthatha lokhu nokudla noma ngaphandle kokudla. Kodwa-ke, uma ngezinye izikhathi uzwa ubuhlungu besisu, kungcono ukuthatha umuthi nokudla.
- Into ebaluleke kakhulu ukuthi, ungayeki ukuthatha umuthi kuze kube yilapho udokotela wakho ekuyala ukuba uyeke. Uma uyeka ukuthatha umuthi ngokuzumayo, ungase ube nokusabela okungathi sína.
Yini okufanele uyenze uma uphuthelwa umthamo wemithi?
Uma ukhohlwa ukuthatha umthamo, thatha ngokushesha nje lapho ukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo wakho olandelayo, yeqa umthamo ongawusebenzisi bese uthatha umthamo wakho olandelayo ngesikhathi esihleliwe.
Ungathathi imithamo emibili ngesikhathi esisodwa nganoma yisiphi isizathu. Kuthiwani uma uphuza umuthi omningi kakhulu? (Ukweqisa umthamo)
Uma ucabanga ukuthi uthathe umuthi omningi kakhulu,
iya eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha. Noma shayela
i-National Poisons Information Centre e-Colombo National Hospital ukuze uthole iseluleko.
Lo muthi unikezwe wena kuphela. Ngakho-ke, ungalokothi uwuhlanganyele nanoma ubani omunye.
Ezinye izinto ezingase zihlangane nalo muthi (Ukusebenzisana)
I-Istradefylline ingase ihlangane neminye imithi, amavithamini, kanye nemikhiqizo yamakhambi oyithathayo. Ngakho-ke, kubalulekile ukutshela udokotela wakho ngakho konke okuthathayo. Lo muthi ungase uhlangane nalokhu okulandelayo:
- Amanye ama-antibiotic, isibonelo i-'Clarithromycin'.
- Eminye imithi enikezwa ukwehlisa i-cholesterol ihlanganisa: `Atorvastatin`, `Lovastatin`, `Simvastatin`.
- Eminye imithi esetshenziswa ukwelapha izifo zesikhunta, isibonelo `i-Ketoconazole`, `i-Itraconazole`.
- Eminye imithi inikezwa ukulawula ukuxhuzula, isibonelo i-`Carbamazepine`, i-`Phenobarbital`, i-`Phenytoin`.
- I-Digoxin, umuthi osetshenziselwa izifo zenhliziyo.
- I-Rifampin, umuthi osetshenziselwa ukwelapha isifo sofuba.
- Izithasiselo zemithi efana ne-St. John's wort.
Lolu hlu alubandakanyi konke, ngakho-ke kubalulekile ukuze uphephe ukutshela udokotela wakho
ngayo yonke imithi, amavithamini, kanye nemikhiqizo yamakhambi oyithathayo.
Izinto okufanele uziqaphele lapho uthatha imithi
- Bona udokotela wakho njalo: Kubalulekile ukuba nokuhlolwa njalo nodokotela wakho ukuze ubone ukuthi izimpawu zakho ziyathuthuka noma ziyanda. Uma izimpawu zakho zingathuthuki noma ziya ziba zimbi kakhulu, tshela udokotela wakho .
- Ukuziphatha okuphoqelekile: Lokhu kungase kubonakale kungavamile, kodwa abanye abantu abasebenzisa lo muthi bangase babe nezifiso ezingalawuleki zokwenza ucansi, bachithe imali ezintweni ezingadingekile, futhi bathenge izinto. Lokhu akulona iphutha lakho, kungaba umphumela omubi womuthi. Ngakho-ke uma wena noma amalungu omndeni wakho nibona noma yiluphi lwalezi zinguquko, ningabi namahloni futhi nitshele udokotela wakho ngokushesha.
- Ukukhulelwa: Njengoba kushiwo ngaphambili, uma uhlela ukukhulelwa, noma usola ukuthi ukhulelwe, lo muthi ungabangela ukukhubazeka okukhulu kokuzalwa enganeni yakho. Ngakho-ke, kubalulekile ukukhuluma nodokotela wakho ngalokhu.
Imiphumela emibi engase ivele ngalo muthi
Njenganoma yimuphi umuthi, i-Istradefylline ingabangela imiphumela emibi. Eminye yayo ingaba yingozi futhi idinga ukunakekelwa kwezokwelapha ngokushesha. Eminye ayibi yingozi kakhulu futhi iyanyamalala ngokuhamba kwesikhathi.
Imiphumela emibi okufanele ibikwe kudokotela wakho ngokushesha Imiphumela emibi evame ukungadingi ukunakekelwa kwezokwelapha (kodwa tshela udokotela wakho uma iqhubeka)
| Uhlobo lomphumela ongemuhle | Incazelo |
|---|
| Ukusabela kokungezwani komzimba | Ukuqubuka kwesikhumba, ukulunywa, ukuvuvukala kobuso, izindebe, ulimi, noma umphimbo. |
| Izinguquko zengqondo nezokuziphatha | Ukungaphumuli, ukucasuka, ukudideka kwengqondo, ukubona noma ukuzwa izinto ezingezona ezangempela (imibono engalungile), imicabango yokuzibulala, ukucindezeleka okukhulu. |
| Ukunyakaza okungalawuleki | Ukunyakaza okusha noma okwandayo okungalawuleki (i-dyskinesia) kobuso, umlomo, noma umzimba ongaphezulu. |
| Ukuziphatha okungenangqondo | Isifiso esingalawuleki sokudlala imidlalo engcolile, ukwenza ucansi, ukuthenga izinto ezingadingekile, noma ukudla ngokweqile. |
| Ukuqunjelwa | Ubunzima bokuya endlini yangasese. |
| Isiyezi | Isiyezi. |
| Isicanucanu | Ukuzizwa sengathi uhlanza. |
| Inkinga yokulala | Ubunzima bokulala. |
Lolu hlu aluhlanganisi yonke imiphumela emibi. Uma uhlangabezana nanoma yini engavamile, khuluma nodokotela wakho ngayo.
Ungayinakekela kanjani imithi?
- Yigcine iphephile , kude nezingane nezilwane ezifuywayo .
- Gcina endaweni yokushisa ephakathi kuka-15 no-30 degrees Celsius (15-30 °C).
- Ungasebenzisi umuthi ophelelwe yisikhathi.
Uma ulahla imithi ephelelwe yisikhathi noma engadingeki, yenza kanjalo ngendlela enobungani nemvelo. Uma kungenzeka, yihambise ohlelweni lokuqoqa imithi ezibhedlela zomphakathi noma kwezinye izitolo zemithi. Uma lokho kungenzeki, khipha amaphilisi ebhodleleni, uwaxube nento efana namaqabunga etiye asetshenzisiwe, ikhofi eligayiwe, noma inhlabathi, bese uwafaka esikhwameni esivalwe kahle bese uwalahla emgqonyeni kadoti.
Ungalokothi uwahlanze endlini yangasese. Umlayezo Wokuya Nawe Ekhaya
- I-Istradefylline umuthi osetshenziselwa ukulawula izimpawu zesifo sikaParkinson, ngokuvamile uhlanganiswa neminye imithi efana neCarbidopa/Levodopa.
- Ngaphambi kokuqala lo muthi, tshela udokotela wakho ngazo zonke izimo zakho zezokwelapha kanye nayo yonke eminye imithi oyithathayo.
- Ungalokothi uyeke ukuthatha imithi ngokuzumayo ngaphandle kweseluleko sikadokotela wakho.
- Uma uhlangabezana nezifiso ezingalawuleki, njengokufisa amaswidi noma izinto ezingadingekile, ngenkathi uthatha umuthi, tshela udokotela wakho ngokushesha, ngoba lokhu kungaba umphumela omubi womuthi.
- Uma ukhulelwe, noma uhlela ukukhulelwa, lo muthi awukufanele. Khuluma nodokotela wakho ngalokhu.
I-Istradefylline, i-istradefylline, isifo sikaParkinson, isifo sikaParkinson, i-Nourianz, umuthi kaParkinson, imiphumela emibi ye-istradefylline isinhala, i-istradefylline isebenzisa isinhala
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