Ingabe ngezinye izikhathi uzizwa ubuhlungu emathanjeni nasemalungeni akho? Noma uzizwa sengathi ikhanda lakho liyakhula kancane futhi imilenze yakho iba mfushane njengoba ukhula? Ungase ucabange ukuthi lezi yizingxenye ezivamile zokuguga. Kodwa ngemuva kwalezi zinto, kungaba yisimo esifihliwe, esingakhulunywa ngaso esibizwa ngokuthi 'Isifo SikaPaget Sethambo'. Leli gama lingase libe lisha kuwe. Kodwa lesi yisimo esingathinta buthule impilo yamathambo ethu. Namuhla, sizokhuluma ngakho kalula, ngendlela ongayiqonda.
Kalula nje, siyini isifo sikaPaget sethambo?
Ukuze siqonde lokhu, ake siqale sibheke ukuthi amathambo ethu asebenza kanjani. Amathambo ethu awawona nje kuphela izinto ezingaphili. Ayizicubu eziphilayo ezizivuselela njalo, zisusa amangqamuzana amadala futhi zenze amasha. Le nqubo siyibiza ngokuthi ukuvuselelwa kwamathambo. Kufana nokudiliza indlu endala bese kwakha entsha, eqinile esikhundleni sayo. Lokhu kubaluleke kakhulu ekugcineni amathambo ethu eqinile.
Kodwa-ke, kumuntu onesifo sikaPaget samathambo, le nqubo ayisebenzi kahle. Nakhu okwenzekayo:
1. Ukuwohloka okusheshayo kwethambo elidala: Amaseli amadala ethambo awohloka ngokushesha kunokujwayelekile.
2. Ukwakheka okungajwayelekile kwethambo elisha: Umzimba wakha ithambo elisha ngokushesha ukuze ugcwalise isikhala. Kodwa-ke, ithambo elisha elakhiwe libuthakathaka, alijwayelekile, likhulu, futhi liyaphuka. Isimo salo sihlukile.
Kalula nje, kufana nalokho okwenzekayo lapho umdlali we-bass onolwazi ezama ukwenza okuthile ngokushesha, futhi umuntu ongazi lutho ngakho ekwenza ngokushesha. Ngisho noma wakha udonga, luzokwelula, lube buthaka, futhi luphuke ngokushesha. Yilokho okwenzeka emathanjeni ethu kulesi sifo. Ngenxa yalokhu , amathambo aphuka kalula (aqhekeke) futhi amathuba okuba nesifo samathambo (i-arthritis) aphezulu kakhulu. Elinye igama lalesi sifo yi-`(Osteitis Deformans)`.
Ingabe lesi sifo siwumdlavuza? Ungasididanisi nesinye 'isifo sikaPaget'!
Lena inkinga abantu abaningi abanayo. Abanye abantu bayesaba ngenxa yokufana kwegama.
Khumbula ngokucacile: Isifo sikaPaget samathambo asiwona umdlavuza.
Kodwa-ke, kukhona into encane okudingeka uyazi lapha. Akuvamile kakhulu , okungukuthi, ngamathuba amancane kakhulu, kunethuba elincane lokuthi umdlavuza wamathambo (`osteosarcoma`) ungavela ethanjeni elithintekile yisifo sikaPaget. Kodwa kubalulekile ukukhumbula ukuthi lokhu akuvamile kakhulu.
Kunezinye izifo eziningana ezibizwa ngokuthi 'i-Paget's, kodwa azihlobene nalesi sifo samathambo.
- Isifo sikaPaget sebele: Lolu uhlobo olungavamile lomdlavuza webele oluvela endaweni yengono.
- Isifo sikaPaget se-vulva:Lolu uhlobo lomdlavuza wesikhumba olungavamile oluvela emlonyeni wesitho sangasese sowesifazane kwabesifazane.
Ngakho-ke, qonda ukuthi nakuba lezi zifo ezintathu zinamagama afanayo, lezi yizimo ezintathu zezokwelapha ezihlukene ngokuphelele ezingahlobene.
Ubani osengozini enkulu yokuthola lesi sifo?
Ososayensi abakayitholi imbangela eqondile yalesi sifo, kodwa kukholakala ukuthi sibangelwa yinhlanganisela yezici zofuzo , okungukuthi, amathonya ofuzo, kanye nezici zemvelo .
Ithebula elingezansi libala ezinye zezinto eziyinhloko ezibangela ubungozi ezibangela ukuthuthuka kwalesi sifo.
| Isici sengozi | Incazelo |
|---|---|
| Ubudala | Abantu abangaphezu kweminyaka engu-50 basengozini enkulu yokuthola lesi sifo. Le ngozi iyanda njengoba iminyaka ikhula. |
| Umlando Womndeni | Uma omunye wezihlobo zakho eziseduze (umama, ubaba, umfowenu noma udadewabo) enalesi sifo, kungenzeka kakhulu ukuthi nawe ube naso. |
| Imvelaphi Yesizwe | Lesi sifo sivame ukubonakala kubantu basemazweni aseYurophu, ikakhulukazi amazwe afana neNgilandi, i-Italy neSpain. |
| Ucansi | Amadoda anamathuba amancane okuthola lesi sifo kunabesifazane. |
Ziyini izimpawu zalesi sifo? Uzibona kanjani?
Into emangalisayo ngalesi sifo ukuthi abantu abaningi abanazo nhlobo izimpawu . Noma banezimpawu ezincane kakhulu, ezingabalulekile. Ngenxa yalokhu, lesi sifo sivame ukutholakala ngengozi lapho kwenziwa ukuhlolwa kwe-X-ray noma kwegazi ngesinye isizathu.
Kodwa-ke, uma kuvela izimpawu, zingase zihluke kuye ngokuthi ithambo lithintekile. Izimpawu ezivame kakhulu zifaka:
- Ubuhlungu bamathambo noma bamalunga: Lolu uphawu oluyinhloko noluvame kakhulu. Lungazwakala njengobuhlungu obuhlala njalo, obujulile ethanjeni elithintekile noma elungeni eliseduze.
- Ukukhubazeka kwamathambo: Ngokuhamba kwesikhathi, ukuma kwamathambo kungashintsha. Isibonelo, uma ugebhezi luthintekile, ikhanda lingase libe likhulu kancane, noma uma imilenze ithintekile, imilenze ingase ikhothame.
- Ukuphuka: Ngenxa yokuthi amathambo asanda kwakheka abuthakathaka, angaphuka kalula ngisho noma ewile noma esengozini encane.
- Ubuhlungu bekhanda nokulahlekelwa ukuzwa: Uma lesi sifo sithinta amathambo ekhanda, ukuqina kwalawo mathambo kungabangela ukucindezelwa kwemizwa, ikhanda elibuhlungu, kanye nokulahlekelwa ukuzwa.
- Ubuhlungu bomhlane: Uma umgogodla uthintekile, kungase kube nezimpawu ezifana nobuhlungu bomhlane kanye nokungazweli emilenzeni.
Udokotela usithola kanjani lesi sifo?
Njengoba kushiwo ngenhla, lokhu kuvame ukutholakala ngengozi. Udokotela wakho angakuthumela kulezi zivivinyo uma unezimpawu noma uma ukuhlolwa ngesinye isizathu kuphakamisa ukusola.
- Ukuhlolwa kwegazi kwe-Alkaline Phosphatase (ALP): Lolu ukuhlolwa kokuqala okunikeza inkomba. Le enzyme ebizwa ngokuthi i-`ALP` ikhiqizwa lapho kwakheka amangqamuzana amathambo. Esifweni sikaPaget, ngoba inqubo yokwakheka kwamathambo iphakeme kakhulu, izinga le-`ALP` egazini liphezulu kakhulu.
- Ama-X-ray: Indlela engcono kakhulu yokuqinisekisa lesi sifo ukusebenzisa i-"X-ray". Izithombe ze-"X-ray" zingahlukanisa ngokucacile amathambo athintekile kwamanye amathambo aphilile. Ungabona ukuthi akhule kanjani ngobukhulu futhi ashintshe isimo.
- Ukuskena Kwamathambo: Lokhu kwenzelwa ukubona ukuthi yimaphi amathambo emzimbeni athintekile yilesi sifo nokuthi sibi kangakanani. Inani elincane lodayi okhipha imisebe lifakwa emthanjeni bese izindawo ezigulayo zibonakala 'njengezindawo ezikhanyayo' uma ziskenwa.
Yiziphi izindlela zokwelapha lokhu? Ingabe kungalapheka ngokuphelele?
Okokuqala, izindaba ezinhle. Okwamanje alikho ikhambi lalesi sifo. Kodwa ungakhathazeki. Kunezindlela zokwelapha eziphumelela kakhulu zokunciphisa ukuqhubeka kwesifo, ukulawula izimpawu, nokuvimbela izinkinga.
Ukwelashwa kuyadingeka kuphela kulabo abanezimpawu, noma labo isifo sabo sithinte izindawo ezibalulekile njengekhanda kanye nomgogodla.
Imithi
Uhlobo oluyinhloko lwemithi esetshenziselwa le njongo ama -bisphosphonates . Le mithi ilawula inqubo yokuqhekeka kwamathambo ngokushesha.
- Okwamanje umuthi osebenza kahle futhi osetshenziswa kabanzi kulesi sigaba.I-Zoledronate . Lona umjovo omncane (`infusion`) ofakwa emthanjeni. Ngokujova kanye kwalomuthi, lesi sifo singalawulwa iminyaka eminingi.
- Kodwa khumbula, le mithi ivimba kuphela ukusabalala kwalesi sifo, kodwa ayikwazi ukulungisa ukukhubazeka kwamathambo osekwenzekile kakade.
Ukuhlinzwa
Ukuhlinzwa kuyadingeka uma kunezinkinga ezibangelwa yilesi sifo. Isibonelo:
- Uma kukhona ukuphuka, yibeke.
- Uma ilunga libhujiswa ngokuphelele yilesi sifo, yenza ukuhlinzwa kokushintsha ilunga ledolo noma lesinqe.
- Ukulungiswa kwamathambo angahlelekile kahle.
- Uma kukhona ukucindezeleka kwemizwa, yehlisa leyo ngcindezi.
Uma lesi sifo sisheshe siqashelwa futhi selashwe, izinkinga ezifana nokuphuka kwamathambo kanye ne-arthritis zingavinjelwa ngokushesha. Ngakho-ke, kubaluleke kakhulu ukuqaphela izimpawu.
Umlayezo Wokuya Nawe Ekhaya
- Isifo sikaPaget seThambo asisona umdlavuza, kodwa yisimo esingamahlalakhona esenza amathambo abe buthaka.
- Abantu abaningi abanazo izimpawu. Izimpawu eziyinhloko kungaba ubuhlungu bamathambo, ukukhubazeka, kanye nokuphuka kwamathambo kalula.
- Lesi sifo singatholakala kalula ngamazinga aphezulu e-alkaline phosphatase egazini kanye nokuhlolwa kwe-X-ray .
- Nakuba lesi sifo singelapheki ngokuphelele, imithi efana ne -bisphosphonates ingasetshenziswa ukuyilawula ngempumelelo nokuvimbela izinkinga.
- Uma uneminyaka engaphezu kwengu-50 ubudala, unomlando womndeni walesi sifo, noma unobuhlungu obungavamile obuqhubekayo emathanjeni, ungabushayi indiva futhi nakanjani ubone udokotela wakho ukuze akunike iseluleko.
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