Isibindi sakho siyisitho esimangalisayo. Senza uketshezi olubizwa ngokuthi 'i-bile' olusisiza ukugaya ukudla okunamafutha esikudlayo. Kodwa kumuntu onesifo esibizwa ngokuthi i-Primary Biliary Cholangitis (PBC), imigudu ethambile ethwala le nyongo yonakele. Lokhu kubangela ukuthi inyongo ingagelezi kahle futhi ivaleke ngaphakathi kwesibindi. Ngokuhamba kwesikhathi, le nyongo evalekile ingaqina ibe amatshe futhi ibangele izifo. Ekugcineni, le nyongo iyabuya futhi ibangele izibazi ngaphakathi kwesibindi. Lena yindlela eyisisekelo ye-PBC.
Kodwa ungakhathazeki. Kunemithi emihle engasiza ekususeni inyongo esibindini futhi inciphise ukwakheka kwalezi zibazi. Kodwa-ke, uma ungayilaphi i-PBC ngendlela efanele, noma uma lesi sifo siba sibi kakhulu, kungase kube nezinkinga ezithile. Namuhla, sizoxoxa ngezinkinga ezivame kakhulu ze-PBC nokuthi singazilawula kanjani.
I-Cirrhosis, isimo esibucayi
I-cirrhosis yilapho amangqamuzana aphilile esibindini sakho ethathelwa indawo yizicubu zesibazi. Kalula nje, isibindi siyaqina kancane kancane sibe yitshe. Lesi simo senzeka ezigabeni zokugcina ze-PBC. Ngalesi sikhathi, isibindi sesivele sonakele kakhulu.
I-cirrhosis yisimo esibi kakhulu okudingeka sisiqaphele, njengoba singaholela ezimweni ezimbi kakhulu njengokwehluleka kwesibindi kanye nomdlavuza wesibindi.
Esikhathini esidlule, i-PBC yayibizwa ngokuthi 'i-primary biliary cirrhosis'. Lokhu kungenxa yokuthi inkinga ye-cirrhosis ihlobene kakhulu nalesi sifo.
Kuphathwa kanjani lokhu?
Udokotela wakho uzokunikeza imithi yokulawula lesi simo.
- Ngokuvamile, ukwelashwa kokuqala kuba umuthi obizwa nge- ursodeoxycholic acid (Ursodiol) . Lokhu kusebenza ngokususa inyongo esibindini nokunciphisa umonakalo esibindini.
- Uma ungazizwa ungcono kakhulu ngalo muthi wedwa, udokotela wakho angase akuncome ukuthi uthathe umuthi obizwa ngokuthi i-obeticholic acid (Ocaliva) ngaphezu kwawo.
- Ngaphezu kwalokho, imithi emisha efana ne -elafibranor (Iqirvo) kanye ne-seladelpar (Livdelzi) manje isivunyelwe ukusetshenziswa ne-ursodeoxycholic acid.
- Enye indlela uhlobo lwemithi ebizwa ngokuthi ama-fibrate . Nakuba empeleni le mithi ivunyelwe ukwehlisa amafutha egazini (ama-lipid), kutholakale ukuthi isebenza kahle kakhulu ezigulini ze-PBC ezingasabeli kahle ku-ursodeoxycholic acid. Ngale ndlela, lapho udokotela esebenzisa umuthi wesimo esingesona leso esivunyelwe sona, sikubiza ngokuthi ukusetshenziswa 'okungekho kulabel'.
Kodwa-ke, kungakhathaliseki ukuthi usebenzisa luphi uhlobo lokwelashwa, uma izicubu zesilonda esibindini ziba ziningi kakhulu futhi isibindi singasakwazi ukusebenza, okuwukuphela kwekhambi ukufakelwa isibindi.Kuphela. Okwenziwayo lapho ukususa isibindi sakho esonakele bese usifaka ngesibindi esivela kumnikeli onempilo.
Ukwanda kwengcindezi emthanjeni esibindini (i-Portal Hypertension)
Lena enye inkinga enkulu. Masiqonde lokhu. Sinomthambo wegazi oyinhloko oletha igazi esibindini sethu. Yilokhu esikubiza ngokuthi 'umthambo we-portal'.
Manje, lapho izicubu zesilonda zakheka ngaphakathi kwesibindi ngenxa yesimo se-cirrhosis esikhulume ngaso ngaphambili, ukugeleza kwegazi kulo 'mthambo we-portal' kuyavinjelwa. Njengokuxinana kwezimoto emgwaqweni, igazi alikwazi ukugeleza kahle futhi libhajwe ngaphakathi kulowo mthambo. Njengoba igazi liqongelela kanje, ingcindezi ngaphakathi kulowo mthambo iyanda kancane kancane. Odokotela babiza lesi simo ngokuthi i-portal hypertension .
Kungani lokhu kuyingozi? Lokhu kucindezela okuphezulu kungabangela ukuqhuma kwemithambo yegazi ebucayi emzimbeni, okubangela ukopha kwangaphakathi . Ngakho-ke, kubaluleke kakhulu ukwelapha lokhu ngokushesha.
Ake siqonde lezi zinkinga ezimbili kusukela kuthebula elingezansi.
| Inkinga | Kalula nje... | Ingozi Eyinhloko |
|---|---|---|
| I-Cirrhosis | Ukwakheka kwezicubu zesibazi esikhundleni sezicubu zesibindi ezinempilo (amatshe esibindi). | Ukwehluleka Kwesibindi kanye Nomdlavuza Wesibindi. |
| Umfutho wegazi ophezulu we-Portal | I-cirrhosis ibangela ukuthi imithambo eletha igazi esibindini ivaleke, okwandisa ingcindezi lapho. | Ukopha kwangaphakathi. |
Yiziphi izindlela zokwelapha lokhu?
Udokotela wakho angase akunike imithi, njenge- beta-blockers, yokunciphisa ingcindezi kulo 'mthambo we-portal'. Lokhu kungalawula ingcindezi yegazi lakho okwesikhashana.
Kodwa khumbula, ukwelashwa okuwukuphela futhi okuhlala njalo okungaqeda ngokuphelele umfutho wegazi ophakeme we-portal ukufakelwa isibindi.Kuphela. Ngoba imbangela eyinhloko yalokhu ukulimala kwesibindi okubangelwa yi-cirrhosis. Njengoba lowo monakalo ungenakulungiswa, indlela yokugcina ukususa isibindi esonakele bese usifaka esisha.
I-PBC yisifo esingalawulwa kahle ngokwelashwa okufanele kanye neseluleko. Ngakho-ke, uma unalesi sifo, ungesabi, hlala uxhumana nodokotela wakho njalo, futhi ulandele ukwelashwa okunqunyiwe ngqo. Leyo yindlela engcono kakhulu yokuhlala uphephile ezinkingeni ezinjalo.
Umlayezo Wokuya Nawe Ekhaya
- I-Primary Biliary Cholangitis (PBC) yisifo esonakalisa imigudu ethambile yesibindi ethwala inyongo.
- Uma lesi sifo singelashwa kahle, kungavela izinkinga ezinkulu ezifana ne-cirrhosis kanye nomfutho wegazi ophezulu we-portal.
- I-cirrhosis yisimo lapho izicubu zesilonda ziqongelela khona esibindini, okuholela ekuhlulekeni kwesibindi ngisho nomdlavuza.
- Umfutho wegazi ophezulu we-portal ukwanda kwengcindezi emthanjeni othwala igazi uye esibindini. Lokhu kungabangela ukopha emzimbeni.
- Uma une-PBC, khuluma nodokotela wakho ngaso sonke isikhathi nganoma yini ekukhathazayo . Kubaluleke kakhulu ukuphuza imithi yakho njengoba uyalelwe futhi ulandele imiyalelo kadokotela wakho.
- Ezimweni eziningi, ikhambi lokugcina kungaba ukufakelwa isibindi.
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