Ingabe ama-ovari akho ayekile ukusebenza ngaphambi kwesikhathi esilindelwe? Ake sifunde ngokungakwazi ukusebenza kahle kwama-ovari okuqala (POI)!

Ingabe ukuya kwakho kwanyanga zonke sekuvele kungajwayelekile? Noma ingabe kuye kwaphela ngokuzumayo futhi akusabonakali kuphinde kuqale? Mhlawumbe uqala ukuzwa izimpawu zokunqamuka kokuya esikhathini ngaphambi kokuba ufinyelele eminyakeni engu-40? Izinto ezinjengalezi zingakwenza uzizwe wesaba kakhulu futhi ukhathazekile. Kodwa ungakhathazeki. Namuhla sizokhuluma ngesizathu esisodwa esingaba khona salesi simo. Lokho ukungasebenzi kahle kwesibeletho okuyinhloko, noma njengoba sikubiza ngamafuphi , i-POI (Ukungasebenzi kahle kwesibeletho okuyinhloko) .

Kuyini Ukuntuleka Kwesibeletho Esiyinhloko (POI)?

Kalula nje, i-POI (i-Primary Ovarian Insufficiency) yilapho ama-ovari akho eyeka ukusebenza kahle ngaphambi kweminyaka evamile, okungukuthi, ngaphambi kweminyaka engu-40. Njengoba wazi, ama-ovari entombazane ayizindlala ezimbili ezincane ezitholakala kuzo zombili izinhlangothi zesibeletho. Lezi yizitho ezikhipha iqanda njalo ngenyanga, esizibiza ngokuthi i-ovulation. Ngaphezu kwalokho, la ma-ovari akhiqiza nama-hormone adingekayo ezintweni eziningi ezibalulekile njengokuya esikhathini nokukhulelwa.

Ngokuvamile, ukuvuthwa kweqanda kowesifazane kuyayeka, noma ukuya esikhathini, cishe eneminyaka engu-51. Kodwa-ke, abanye abantu abane-POI ngokuzumayo bayayeka ukuya esikhathini. Kwabanye, i-POI itholakala ngemva kwezinyanga noma ngisho neminyaka yokuya esikhathini okungajwayelekile.

Lesi simo sasibizwa ngokuthi "Ukwehluleka Kwesibeletho Ngaphambi Kwesikhathi." Kodwa manje odokotela bakhetha ukusebenzisa igama elithi "Ukungapheleli." Lokhu kungenxa yokuthi ucwaningo luthole ukuthi abesifazane abane-POI ngezinye izikhathi banama-ovari asebenzayo, okusho ukuthi bangakhipha amaqanda ngezikhathi ezingavamile. Lokhu kusho ukuthi ngisho nomuntu one-POI ngezinye izikhathi angakhipha iqanda futhi akhulelwe! Eqinisweni, phakathi kuka-5% no-10% wabantu abane-POI bakhulelwa bodwa ngaphandle kokwelashwa kokungabi nabantwana. Yingakho i-POI ibizwa nangokuthi "i-Decreased Ovarian Reserve."

Sivame kangakanani lesi simo?

I-POI empeleni iyisimo esingavamile . Sithinta cishe u-1% wabesifazane abaneminyaka ephakathi kuka-15 no-44. Singathinta kokubili labo abaye baba nezingane nalabo abangakaze babe nezingane. Kodwa-ke, sivame kakhulu kwabesifazane abaneminyaka engaphezu kuka-30.

I-POI ithinta kanjani umzimba wakho?

Ukuntuleka Okuyinhloko Kwesibeletho kubangela ukuthi umzimba wakho ube namazinga aphansi e-hormone i-estrogen . Lapho amazinga e-estrogen ehla, ungase ube nezimpawu ezifana nalezo zokunqamuka kokuya esikhathini. Isibonelo, ungase ube nokushisa komzimba, ukwehla kwesifiso socansi, kanye nokushintsha kwemizwelo. Kungandisa futhi ingozi yakho yokuthola ezinye izimo, njenge-osteoporosis nesifo senhliziyo.

Abesifazane abaningi abane-POI banenkinga yokuthola abantwana, okusho ukungazali.Kungenzeka. Kodwa-ke, udokotela wakho angase akwazi ukukusiza ukuthi ukhulelwe umntwana. Kunezindlela zokwelapha lokhu, njengeziqanda ezinikelayo , ukuvundisa nge-in vitro (IVF) , noma imithi yokuzala.

Yiziphi izimbangela ze-POI?

Ezimweni eziningi, odokotela abazi imbangela eqondile ye-POI . Lokhu kubizwa ngokuthi i-idiopathic POI . Kodwa-ke, ucwaningo lukhombisile ukuthi cishe kwesithathu samacala, kungase kube nokuxhumana kwezakhi zofuzo.

Ezinye izimbangela ezingaba khona ze-POI yilezi:

• Izinkinga zokuzivikela komzimba: Isibonelo, isifo sika-Addison, isifo samathambo esibizwa ngokuthi i-rheumatoid arthritis, noma isifo se-thyroid. Kulezi zifo, amasosha omzimba ethu ahlasela izitho zethu zomzimba. Lokhu kungalimaza ama-ovari.
• Ukwelashwa komdlavuza: Ukwelashwa okufana ne-chemotherapy kanye nemisebe kungalimaza ama-ovari.
• Izinkinga zofuzo: Isibonelo, i-Turner syndrome – ebangelwa ukungajwayelekile kwenye yama-chromosome amabili e-X yowesifazane. Kanye ne-Fragile X syndrome – ebangelwa izinguquko ku-gene ebizwa ngokuthi i-FMR1.
• Ukususwa kwesibeletho: Ngezinye izikhathi, lapho isibeletho sisuswa, ukuhlinzekwa kwegazi kuma-ovari kunganqamuka, okunganciphisa ukusebenza kwawo. Kodwa-ke, uma isibeletho sisuswa kuphela futhi ama-ovari eshiywa ephelele, i-POI ngokuvamile ayiveli.
• Ukutheleleka: Ukutheleleka okufana ne-mumps kanye ne-HIV kungalimaza nama-ovary. Lokhu kucatshangwa ukuthi kungenxa yokuthi ama-antibodies akhiqizwa ngokumelene nokutheleleka ahlasela ama-ovary.
• Ukuchayeka isikhathi eside kumakhemikhali anobuthi: Ukuchayeka isikhathi eside kumithi yokubulala izinambuzane, intuthu kagwayi, kanye nezinye izinto ezinobuthi nakho kungaba yimbangela.

Ziyini izimpawu ze-POI?

Uphawu oluvame kakhulu lwe-POI ukungajwayelekile noma ukuyeka ngokuphelele ukuya esikhathini . Kodwa-ke, abanye besifazane bangase bangabi nazo izimpawu ezinkulu ngisho noma bene-POI.

Ezinye izimpawu zingase zihlanganise:

• Ukuya esikhathini okungajwayelekile noma okuyekile.
• Ubunzima bokukhulelwa.
• Ukuncipha kwesifiso socansi.
• Ubunzima bokugxilisa ingqondo.
• Intukuthelo evame ukuthukuthela nokucasuka.
• Amehlo omile.
• Ukushisa okukhulu kanye nokujuluka ebusuku.
• Ukoma kwesitho sangasese sowesifazane.
• Ucansi olubuhlungu ngenxa yokoma kwesitho sangasese sowesifazane.

Cabanga nje, unomngane ongakaze aye esikhathini sakhe izinyanga eziningi. Akakwazi ukulala ebusuku, uyajuluka, futhi uthukuthela ngezinto ezincane kakhulu. Angase azilahle lezi zinto, athi, "Kumelwe ukuba ukucindezeleka." Kodwa lezi zingaba izimpawu ze-POI.

Ungayibona kanjani i-POI?

Uma unalezi zimpawu, kufanele ubonane nodokotela. Udokotela uzokwenza ukuhlolwa ngokomzimba , ukuhlolwa kwesinqe, kanye nomlando wezokwelapha. Udokotela wakho uzobuza nangomjikelezo wakho wokuya esikhathini, ukuthi uke wakhulelwa yini ngaphambili, nokuthi usebenzisa yini izindlela zokuvimbela inzalo. Lokhu kungasiza udokotela wakho ukuthi ahlole i-POI.

Okulandelayo, udokotela wakho cishe uzoyala ukuhlolwa kwegazi okumbalwa ukuze kulinganiswe amazinga amahomoni athile emzimbeni wakho. Lokhu kufaka phakathi ukuhlola amazinga akho amahomoni i-Follicle Stimulating Hormone (FSH) , i-Estrogen, ne -Prolactin .

Ezinye izivivinyo udokotela angazisebenzisa zifaka:

• Ukuhlolwa kwe-Karyotype ukuhlolwa kwegazi ukuhlola izifo zofuzo.
• I-ultrasound ye-pelvic iyisivivinyo sokubheka ama-ovari kanye nesibeletho.
• Ukuhlolwa kokukhulelwa .
• Ukuhlolwa kwama-antibody ukuhlola izifo ezihlasela amasosha omzimba.

Odokotela baxilonga i-POI uma ungaphansi kweminyaka engama-40 ubudala futhi:

• Uma ungenayo inyanga noma uma ukuya kwakho esikhathini kungavamile.
• Ukuhlolwa kwegazi kubonisa ukuthi amazinga akho ama-hormone asezingeni lowesifazane osedlule esikhathini sokunqamuka kokuya esikhathini.

Iphathwa kanjani i-POI?

Kunezindlela eziningana zokwelapha i-POI. Kuya ngeminyaka yakho, izimpawu, nokuthi ufuna ukuba nezingane . Ukwelashwa kokungasebenzi kahle kwesibeletho esiyinhloko kufaka phakathi:

• Ukunikeza umzimba wakho ama-hormone angasakhiqizi amaqanda akho.
• Ukwelapha izimpawu ze-POI (isib. ukujuluka ebusuku, ukoma kwesitho sangasese sowesifazane).
• Ukunciphisa ingozi yezinye izifo ezingabangelwa yi-POI.
• Ukwelapha izimo zezokwelapha eziyisisekelo ezenza izimpawu ze-POI zibe zimbi kakhulu.

Ukwelashwa Kokufaka Ama-hormone (HRT)

Ukwelashwa kokushintsha ama-hormone (HRT) kuthatha indawo yama-hormone angakhiqizi amaqanda akho. Lokhu kungenziwa ngokukunika i-estrogen yodwa noma ngokukunikeza kokubili i-estrogen ne-progesterone.Ukwelashwa ngama-hormone kungasiza ekunciphiseni izimpawu ze-POI, njengokujuluka ebusuku kanye nokomisa kwesitho sangasese sowesifazane. Kunganciphisa nengozi yakho ye-osteoporosis nezinye izifo ezingase zenzeke nge-POI. Udokotela wakho angakunikeza ukwelashwa ngama-hormone ngezindlela ezahlukene, njengamaphilisi, okhilimu, ama-gel, ama-patches, noma ama-ring esitho sangasese sowesifazane.

Uma uqala i-HRT, kuzodingeka uthathe ukwelashwa kuze kube yilapho kufika iminyaka yokunqamuka kokuya esikhathini ngokwemvelo (iminyaka engu-51-52). Kufanele uxoxe ngezinzuzo nezingozi ze-HRT nodokotela wakho bese unquma ukuthi ikulungele yini.

Ngaphezu kwe-HRT, ezinye izindlela zokwelapha zifaka:

• Ukuthatha amaphilisi e -calcium ne-vitamin D ukunciphisa ingozi yokuncipha kwamathambo.
• Zivocavoce njalo, phakamisa izinsimbi (ukuze amathambo akho abe nempilo), futhi ugcine isisindo esinempilo.
• Uma unethemba lokuqala umndeni futhi ube nezingane, kubalulekile ukuhlola izindlela zokwelapha ukuzala .

Uma ungahleli ukukhulelwa, ungakhohlwa ukukhuluma nodokotela wakho ngezindlela zokuvimbela inzalo.

Ingabe lokhu kungaguqulwa? Ingabe ama-ovary azoqala ukusebenza futhi?

Cha, ukuntuleka kwe-Ovarian Primary akukwazi ukuguqulwa. Odokotela bangelapha izimpawu, imiphumela emibi, kanye nezimo ezihlobene nayo, kodwa ayinakwelashwa ngokuphelele.

Cishe ama-25% abesifazane abane-POI bayakwazi ukukhipha amaqanda okungenani kanye ngemva kokuxilongwa . Kodwa-ke, okwamanje akukho ukwelashwa okungenza ama-ovari akho aqale ukusebenza futhi. Ukwelashwa kwe-POI kugxile ekulawuleni izimpawu kanye nokunciphisa ingozi yezinye izinkinga zempilo ezingabangelwa yi-POI.

Ingabe i-POI ingavinjelwa?

Ukuntuleka Okuyinhloko Kwesibeletho Ngokuvamile akukwazi ukuvinjelwa. Kodwa-ke, abesifazane abasengozini enkulu yokuthola i-POI bangase bafune ukucabangela ukugcinwa kokuzala uma behlela ukuba nezingane. Uma ukhathazekile nge-POI, khuluma nodokotela wakho.

Ubani osengozini enkulu yalokhu?

Abantu abalandelayo basengozini enkulu yokuthola ukungasebenzi kahle kwe-Ovarian Primary:

• Kulabo abaneminyaka engaphezu kwengu-35 ubudala.
• Abazali bemvelo kulabo abane-POI.
• Kulabo abanezinkinga zokuzivikela komzimba noma izimo ezithile zofuzo.
• Labo abaye bahlinzwa i-pelvic, i-chemotherapy, noma ukwelashwa ngemisebe.

Impilo izoba njani nge-POI? (Isibikezelo)

Ukuntuleka Kwesibeletho Esiyinhloko ngokuvamile kuyisimo esihlala njalo.Abesifazane abaningi abanalesi simo badinga ukuthatha ukwelashwa ngama-hormone isikhathi eside ukuze balawule izimpawu futhi banciphise ingozi yezinkinga.

I-POI ivame ukukushiya uzizwa udangele, unesizungu, futhi sengathi ulahlekelwe okuthile. Lo muzwa ungaba mkhulu kakhulu uma usazama ukukhulelwa. Kukhona amaqembu okusekela kanye nezinsizakalo zokweluleka ezizokusiza ngalesi sikhathi. Ngalolu sizo, ungalawula imizwa yakho futhi uthole izindlela zokubhekana nalesi simo.

Yiziphi ezinye izinkinga zempilo ezingabangelwa yi-POI?

Abesifazane abane-POI banamazinga aphansi e-estrogen. Uma amazinga e-estrogen ephansi, nawe usengozini yezinye izinkinga zempilo. Ezinye zalezi zinkinga zifaka:

• I-Osteoporosis
• Isifo senhliziyo
• I-Hypothyroidism (I-thyroid engasebenzi kahle)
• Ukungazali
• Ukukhathazeka Nokucindezeleka

Kufanele ubonane nini nodokotela?

Uma ungazange uye esikhathini izinyanga ezintathu, bonana nodokotela ngokushesha. Kunezizathu eziningi zokuthi kungani ukuya kwakho esikhathini kungenzeka ukuthi kuyeke, okuhlanganisa ukukhulelwa, ukucindezeleka, noma izinguquko zamahomoni. Udokotela wakho angakusiza ukuthi uthole ukuthi yini ngempela ebangela ukuba ukuya kwakho esikhathini kume.

Yini okufanele uyibuze udokotela?

Uma une-Primary Ovarian Insufficiency, ungase ufune ukubuza udokotela wakho imibuzo efana nalokhu:

• Ukuntuleka Kwesibeletho Esiyinhloko Kuyithinta Kanjani Impilo Yami Yonke?
• Ingabe ngizodinga ukwelashwa kokushintsha ama-hormone (HRT)? Isikhathi esingakanani?
• Ingabe ngizodinga ukuvimbela inzalo?
• Ngingalutholaphi usizo lwengqondo kanye nokwelulekwa?
• Iyiphi indlela engcono kakhulu yokwamukela ingane?

Uyini umehluko phakathi kwe-POI kanye nokwehluleka kwe-Ovarian ngaphambi kwesikhathi / Ukunqamuka kokuya esikhathini ngaphambi kwesikhathi?

Odokotela bangase basebenzise la magama ngokushintshana ukuchaza ukunqamuka kokuya esikhathini ngaphambi kweminyaka engu-40. Ukunqamuka kokuya esikhathini ngaphambi kwesikhathi yilapho ukuya esikhathini kuphela ngaphambi kweminyaka engu-40 futhi ungakwazi ukukhulelwa futhi. Ku-POI, ama-ovari ngezinye izikhathi angayeka ukusebenza okwesikhashana, ngakho-ke kuhlukile kancane.

Ungakhulelwa yini une-POI?

Yebo, kunethuba lokuthi owesifazane one-POI angakhulelwa. Uma une-POI futhi uzama ukukhulelwa, udokotela wakho wokuzala angakweluleka ngezinketho zakho. Futhi, uma ungazami ukukhulelwa, khuluma nodokotela wakho ngezindlela zokuvimbela ukukhulelwa.

Okokugcina, okufanele ukukhumbule

Ukuntuleka Okuyinhloko Kwesibeletho (i-POI) yisimo lapho ama-ovari akho eyeka ukusebenza ngaphambi kokuba abe neminyaka engu-40. Lokhu kungabangela izimpawu ezingakhululekile futhi kwandise ingozi yakho yezimo zempilo ezifana ne-osteoporosis noma isifo senhliziyo.

Kuvamile ukuzizwa udabuke futhi ukhathazekile uma uthola ukuthi une-POI. Ikakhulukazi uma ubunethemba lokuba nomntwana. Kodwa ngokwelashwa okufanele nokusekelwa, ungaqhubeka nokuphila impilo enempilo. Khuluma nodokotela wakho ngezinto ezikukhathazayo. Thola ukwesekwa ngumlingani wakho, umndeni, nabangani ukuze bakusize ubhekane nesimo. Khumbula, awuwedwa.

Ukungasebenzi kahle kwe-ovary , ukungasebenzi kahle kwe-ovarian, i-POI, ukunqamuka kokuya esikhathini kusenesikhathi, impilo yabesifazane, ukungalingani kwama-hormone, ukungabi nabantwana