Ngiyaqonda ukwesaba, ukukhathazeka, kanye nokungaqiniseki okuzwayo lapho udokotela wakho ekutshela noma othandekayo wakho ukuthi unomdlavuza. Ngesikhathi esifanayo, lapho udokotela wakho ekutshela ngokwelashwa okubizwa ngokuthi “R-CHOP,” cishe unemibuzo eminingi efika engqondweni yakho, njengokuthi, “Kuyini? Kwenzani?” Ungakhathazeki. Namuhla, sizoxoxa ngokuthi iyini i-R-CHOP, ukuthi yenzani, nokuthi ungayibhekana kanjani nayo ngendlela elula kakhulu ongayiqonda.
Kalula nje, iyini i-R-CHOP?
I-R-CHOP iyinhlanganisela yemithi emihlanu ebulala amangqamuzana omdlavuza . Iyindlela yokwelapha ephumelela kakhulu yohlobo lomdlavuza olubizwa ngokuthi i-non-Hodgkin lymphoma . Uhlamvu ngalunye egameni lubhekisela kumuthi osetshenziswa kulokhu kwelashwa.
| Incwadi | Umuthi kanye nesenzo sawo |
|---|---|
| R | I-Rituximab: Lokhu kuyindlela yokwelapha eqondiwe. Ngokukhethekile, lo muthi unamathela kuphrotheni ekhethekile ebusweni bamangqamuzana omdlavuza. Lokhu kuvumela amasosha omzimba wethu ukuthi aqaphele futhi abhubhise kalula lawa maseli omdlavuza. |
| C | I-Cyclophosphamide: Lona umuthi we-chemotherapy. Imithi ye-chemotherapy isebenza ngokubhubhisa amaseli ahlukana ngokushesha, njengamaseli omdlavuza. |
| H | I-Doxorubicin hydrochloride (i-Hydroxydaunomycin): Lona futhi umuthi we-chemotherapy. |
| O | I-Vincristine sulfate (i-Oncovin): Lona omunye umuthi we-chemotherapy. |
| P | I-Prednisone: Lolu uhlobo lwe-steroid (i-corticosteroid). Iphinde ibulale amangqamuzana omdlavuza. Iphinde isize ekunciphiseni ukusabela kokungezwani komzimba okungenzeka ngeminye imithi ye-R-CHOP. |
Njengoba ubona, lokhu kuhilela imithi yokwelapha ngamakhemikhali kanye nomuthi ohlasela amasosha omzimba (i-Rituximab). Yingakho odokotela ngezinye izikhathi bebiza lokhu kwelashwa ngokuthi “i-immuno-chemotherapy.”
Yiziphi izinhlobo zomdlavuza ezisetshenziselwa ukwelashwa kwe-R-CHOP?
Lokhu kwelashwa kunikezwa kakhulu uhlobo lomdlavuza olubizwa ngokuthi i-non-Hodgkin lymphoma . Kusebenza kakhulu futhi kuhlobo oluvame kakhulu lwe -B-cell lymphoma (i-DLBCL) . Ngaphezu kwalokho, i-R-CHOP isetshenziselwa nezinhlobo ezilandelayo zomdlavuza :
- I-follicular lymphoma ethuthukisiwe
- I-Mantle cell lymphoma
- I-Waldenstrom macroglobulinemia
Kwezinye izimo, udokotela wakho angase anqume ukunikeza i-R-CHOP kanye nokwelashwa kwezinye izinhlobo zomdlavuza.
Ukwelashwa kusebenza kanjani?
Ukwelashwa kwe-R-CHOP kunikezwa “ngemijikelezo.” Umjikelezo ngamunye uvame ukuthatha amasonto amathathu (izinsuku ezingu-21). Kunezingxenye ezimbili kulo mjikelezo:
1. Izinsuku zokwelapha: Izinsuku onikwa ngazo imithi.
2. Izinsuku zokuphumula: Izinsuku zokuvumela umzimba wakho ukuthi ululame futhi ululame ngaphambi komzuliswano olandelayo.
Izinsuku zokwelapha
Umuthi unganikezwa isikhathi esiyizinsuku ezinhlanu. I-Prednisone (i- steroid ) iyiphilisi oligwinyayo. Eminye imithi emine inikezwa njengesixazululo sikasawoti emthanjeni (i-intravenous infusion - IV). Lokhu kuzodinga ukuthi uye esibhedlela noma emtholampilo. Lapho uzohlala esihlalweni ngenkathi umshini ufaka umuthi kancane kancane emthanjeni emzimbeni wakho. Lo mthambo ungase ube engalweni yakho, esandleni, noma esifubeni. Uma ukwelashwa kunikezwa ngesifuba, idivayisi encane ebizwa ngokuthi i-`port-a-cath` (chemo port) ingafakwa ngaphansi kwesikhumba.
Ngosuku lokuqala lokwelashwa, uzonikezwa umuthi wokuvimbela isicanucanu. Uzonikezwa nomuthi wokuvimbela ukungezwani komzimba. I-RituximabKuvamile ukuzizwa unesiyezi futhi ufudumele lapho unikezwa umuthi. Yingakho lo muthi unikezwa ngokucophelela ekuqaleni. Kodwa akukho okufanele ukhathazeke ngakho, njengoba uzonikezwa umuthi odingekayo kusengaphambili ukuze uvimbele ukungezwani komzimba okukhulu.
Izinsuku zokuphumula
Emjikelezweni ojwayelekile, uzoba nezinsuku ezingaba ngu-16 zokuphumula ngemva kokwelashwa. Umzimba uzizwa ukhathele kakhulu njengoba ukwelashwa kwe-R-CHOP kubhubhisa amangqamuzana omdlavuza. Ngakho-ke kuyinto evamile ukuzizwa ukhathele kakhulu ngalezi zinsuku. Phakathi nalesi sikhathi, kuhle kakhulu ukucela usizo emndenini nakubangani ngemisebenzi yansuku zonke.
Phakathi nalezi zinsuku zokuphumula, uma uzizwa ukhululekile, udokotela uncoma ukwenza ukuzivocavoca okulula, njengokuhamba. Kubaluleke kakhulu futhi ukuphuza amanzi amaningi nokudla ukudla okunempilo .
Ziyini izingozi nemiphumela emibi yalokhu kwelashwa?
Njenganoma yikuphi ukwelashwa, i-R-CHOP ingabangela imiphumela emibi. Kodwa khumbula, udokotela wakho uzokunikeza imithi oyidingayo ukuvimbela noma ukulawula eminingi yale miphumela emibi. Akuwona wonke umuntu othola yonke le miphumela emibi. Iyahlukahluka kuye ngomuntu nomuntu. Ake sibheke eminye yemiphumela emibi evame kakhulu.
| Imiphumela emibi evamile | Okufanele ukwazi nokuthi yini okufanele uyenze |
|---|---|
| Umchamo obomvu/opinki | I-Doxorubicin inombala obomvu. Umchamo wakho ungase ube bomvu/upinki kuze kube amahora angu-48 ngemva kokwelashwa. Lokhu kuvamile, ungakhathazeki. |
| Isicanucanu nokuhlanza | Ngisho noma uthatha imithi yokucanuzela, ungase uzizwe ucanuzela kancane. Esikhundleni sokudla ukudla okukhulu, okunamafutha, okunongwe kakhulu, yidla ukudla okuncane, okuvamile. |
| Ukulahlekelwa izinwele | Lokhu kuvamile nge-chemotherapy. Ukulahlekelwa izinwele kungaqala zingakapheli amasonto amathathu kusukela kumthamo wokuqala. Kodwa-ke, izinwele ziphinde zikhule ngemva kokuphela kokwelashwa. |
| Ukugodola nomkhuhlane | Ukwelashwa ngamakhemikhali kunganciphisa inani lamaseli akho amhlophe egazi, okwandisa ingozi yakho yokutheleleka. Uzonikezwa umjovo obizwa ngokuthi i-G-CSF, osiza amaseli akho amhlophe egazi akhule. Kodwa-ke, uma uba nomkhuhlane, tshela udokotela wakho ngokushesha. |
| Ukukhathala okukhulu (Ukukhathala) | Ukwelashwa kungabangela ukwehla kwamangqamuzana abomvu egazi, okubangela i-anemia. Uma uzizwa ukhathele, phumula. Cela usizo ngemisebenzi yansuku zonke. |
| Ukuphuka/ukopha okulula | Lesi simo singabangelwa ukwehla kwama-platelet. Qaphela ukuthi ungalimali. Tshela udokotela wakho uma ubona imivimbo eminingi emzimbeni wakho. |
| Ukuba ndikindiki/ukuthuthumela emilenzeni | Lokhu kubizwa ngokuthi i-peripheral neuropathy. Uma uzizwa uthukuthele noma usha ezandleni noma ezinyaweni zakho, tshela udokotela wakho. |
Khumbula, umkhuhlane ungaba uphawu lokutheleleka okukhulu. Uma umkhuhlane wakho ungaphezu kuka-100.4°F (38°C), shayela udokotela wakho noma isibhedlela ngokushesha.
Ngaphezu kwalokhu, ungase ube nezilonda emlonyeni, ukuqubuka kwesikhumba, ikhanda elibuhlungu, ukuqunjelwa noma uhudo, ubuhlungu besifuba, ukuqwasha, kanye nokushintsha kwemizwa. Khuluma nodokotela wakho nganoma yikuphi kwalokhu.
Kufanele ngimshayele nini udokotela?
Tshela udokotela wakho ngokushesha uma uthola izimpawu ezintsha noma uma kukhona izimpawu zakho eziba zimbi kakhulu ngesikhathi sokwelashwa, ikakhulukazi uma uthola umkhuhlane.
Uma kwenzeka isimo esiphuthumayo njengobunzima bokuphefumula noma ubuhlungu besifuba obungazelelwe, hamba uye eMnyangweni Wezimo Eziphuthumayo (ETU) wesibhedlela esiseduze ngokushesha.
Ngingenza kanjani ukuthi lesi sikhathi sokwelashwa sibe lula kimi?
Le mpi akuyona into okufanele uyilwe wedwa. Kunezinto ezimbalwa ongazenza ukuze wenze lesi sikhathi sibe lula.
- Yaziswa: Khuluma nodokotela wakho mayelana nokwelashwa kwakho nokuthi yini ongayilindela. Ungesabi ukubuza imibuzo.
- Cela usizo: Cela usizo emndenini nakubangane ngemisebenzi yasekhaya, ekulungiseleleni ukudla, nasekuyeni esibhedlela.
- Yidla futhi uphuze kahle: Yidla ukudla okunomsoco. Phuza amanzi amaningi kanye noketshezi.
- Thola ukwesekwa: Buza udokotela wakho ngamaqembu okusekelana lapho abanye abadlula ekwelashweni okufanayo nawe bebhekene nomdlavuza. Kuyisibusiso esikhulu ukuba nomuntu ongabelana naye okuhlangenwe nakho kwakho.
Amaviki ambalwa okuqala okwelashwa kwe-R-CHOP angaba isikhathi esinzima. Izinsuku zokusebenzisa imithi zingaba zinde futhi imiphumela emibi ingaba nzima ukubhekana nayo. Kodwa kubantu abaningi, imiphumela ye-R-CHOP ibaluleke kakhulu. Ukuhlanganiswa kwale mithi emithathu (eqondiwe, i-chemo, kanye ne-steroids) kusebenza kahle ukubulala amangqamuzana omdlavuza. Kuye ngokuthi uxilongwe kanjani, lokhu kungaholela ekuphumuleni okuphelele komdlavuza.
Umlayezo Wokuya Nawe Ekhaya
- I-R-CHOP iyinhlanganisela ephumelela kakhulu yemithi emihlanu esetshenziselwa ukwelapha umdlavuza njenge-non-Hodgkin lymphoma.
- Ukwelashwa kunikezwa “ngemijikelezo.” Phakathi nalesi sikhathi, kuvamile ukuba nemiphumela emibi njengokukhathala, isicanucanu, nokulahlekelwa izinwele.
- Imiphumela eminingi emibi ingalawulwa. Khuluma njalo nethimba lakho lezokwelapha ngayo.
- Uma uba nomkhuhlane ngesikhathi sokwelashwa, kubheke njengesimo esiphuthumayo bese ucela iseluleko sezokwelapha ngokushesha.
- Akudingeki ukuthi udlule kulolu hambo wedwa. Thola ukwesekwa emndenini, kubangani, kanye nethimba lakho lezokwelapha. Unamandla. Ungakwenza lokhu.
I-R-CHOP, umdlavuza, i-Non-Hodgkin lymphoma, i-chemotherapy, ukwelashwa okuqondiwe, ukwelashwa komdlavuza, imiphumela emibi
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