Ingabe nawe unomuzwa ohlala njalo wobuthakathaka, ubuhlungu bamalunga, nezinkinga zesikhumba? Mhlawumbe udokotela wakho ukucele ukuthi wenze isivivinyo se-ANA ngesikhathi esinjengalesi. Uma uzwa leli gama, abanye abantu bayesaba kancane, becabanga ukuthi, "Lolu hlobo lwesifo esikhulu lungolwani?" Kodwa empeleni luwukuhlolwa kwegazi okulula kakhulu, okuvamile. Ngakho ake sicacise yonke imibuzo onayo ngakho namuhla. Ake sibone ukuthi lolu vivinyo lwe-ANA luyini, kungani lwenziwe, nokuthi imiphumela ithini ngempela.
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Kalula nje, luyini lolu vivinyo lwe-ANA?
Ukuze siqonde lokhu, sidinga kuqala ukwazi ukuthi ayini ' ama-antibodies '. Cabanga ukuthi umzimba wethu uyizwe. Khona-ke ama-antibodies afana namandla okuzivikela alelo zwe . Umsebenzi wala ma-antibodies ukubona nokulwa nezitha ezifana namagciwane (amagciwane, amagciwane) avela ngaphandle nokusivikela ezifweni.
Kodwa, ngezinye izikhathi izivikelo zethu zenza iphutha elincane. Esikhundleni sesitha esivela ngaphandle, ziphambanisa amangqamuzana ethu aphilile nezicubu njengesitha. Bese ziqala ukuhlasela lawo maseli aphilile. Sibiza la ma-antibodies ahlasela imizimba yethu ngephutha ngokuthi 'ama-autoantibodies' .
Ngakho-ke, ukuhlolwa kwe-Antinuclear Antibody (ANA) kuwukuhlolwa kwegazi okuhlola lawa 'autoantibodies' egazini lakho. I-'Antinuclear' isho ukuthi 'ngokumelene ne-nucleus'. Lokhu kusho ukuthi lawa ma-autoantibodies ahlasela ngqo i-nucleus, okuyisikhungo sokulawula samaseli ethu.
Ukuba khona kwala ma-autoantibodies emzimbeni wakho kuyisibonakaliso sokuthi ungase ube 'nesifo sokuzivikela komzimba ', isimo lapho amasosha omzimba eziphendukela khona . Isibonelo:
- Isifo se-Lupus (i-Systemic Lupus Erythematosus - SLE)
- Isifo Samathambo Esibangelwa Yi-Rheumatoid
- I-Scleroderma
- Isifo SikaSjögren
Yiziphi izimpawu ezingenza udokotela ancome lolu vivinyo?
Izifo ezihlasela amasosha omzimba zinezimpawu eziningi. Uma usunesinye noma ngaphezulu kwalezi zimpawu ezingezansi isikhathi eside, udokotela wakho angase akuncome ukuthi uhlolwe i-ANA ukuze athole imbangela.
| Isibonakaliso | Incazelo |
|---|---|
| Ubuhlungu bamalunga nemisipha | Ukuqina kwamalunga ekuseni, ukuvuvukala, kanye nobuhlungu obungapheli. |
| Ukukhathala | Ukuzizwa ungenampilo kungakhathaliseki ukuthi ulala kangakanani. |
| Umkhuhlane ophindaphindayo | Ukuba nomuzwa ohlala njalo wokushisa nokushisa ngaphandle kwesizathu esithile. |
| Ukuqhuma Kwebhathane | Ukuqubuka okubomvu okufana nokwebhabhathane kuvela ezihlathini nasemakhaleni (lokhu kuyisibonakaliso esiyinhloko se-lupus). |
| Ukuba ndikindiki ezithweni zomzimba | Ukuqaqamba noma ukuba ndikindiki ezandleni noma ezinyaweni. |
| Ukulahlekelwa izinwele | Ukulahlekelwa izinwele okuningi kunokujwayelekile. |
| Ukuzwela ekukhanyeni | Ukucasuka kwesikhumba noma ukungakhululeki uma kuvezwa elangeni noma ekukhanyeni okukhulu. |
Izinto okufanele uzazi ngaphambi kokwenza isivivinyo
Akukho okukhethekile okudingeka ukwenze ngaphambi kwalokhu kuhlolwa. Akudingeki uzile ukudla noma wenze noma yini ekhethekile. Kodwa-ke, kubalulekile ukutshela udokotela wakho ngayo yonke imithi oyithathayo njengamanje (kufaka phakathi amavithamini kanye nezithasiselo ). Eminye imithi ingathinta umphumela we-ANA.
Ulwenza kanjani lolu vivinyo?
Lena inqubo elula kakhulu. Ilabhorethri ithatha isampula yegazi elincane emthanjeni osengalweni yakho. Le nqubo iqedwa ngemizuzu embalwa. Kufakwa iplasta encane endaweni lapho igazi lithathwe khona. Ngemva kwalokho, ungaya ekhaya njengokujwayelekile. Isampula yegazi ihlolwa elabhorethri.
Ingabe umphumela we-ANA... Ulungile (+)? Ungalungile (-)? Kusho ukuthini lokhu?
Lena yinkinga enkulu kunazo zonke umuntu anazo.
- Umphumela ongemuhle (-): Lokhu kusho ukuthi awekho ama-autoantibodies atholakale egazini lakho. Lokhu kusho ukuthi akunakwenzeka ukuthi unesifo sokuzivikela komzimba.
- Umphumela omuhle (+): Lokhu kusho ukuthi ama-autoantibodies atholakale egazini lakho.
Kodwa kukhona into okudingeka uyikhumbule lapha.
Into ebalulekile ukuthi ukuhlolwa kwe-ANA okuhle akusho ukuthi unesifo sokuzivikela komzimba.
Eqinisweni, phakathi kuka-3% no-15% wabantu abaphilile abangenazo izimo zezokwelapha eziyisisekelo bangaba nokuhlolwa kwe-ANA okuhle. Kungabangelwa futhi yimithi ethile, ukutheleleka ngegciwane , nezinye izimo zezokwelapha.
Lokhu kusho ukuthi ukuhlolwa kwe-ANA kuyingxenye eyodwa kuphela yokuxilongwa. Udokotela wakho uzofinyelela esiphethweni sokugcina ngokuhlanganisa izimpawu zakho, ukuhlolwa ngokomzimba , kanye nezinye izivivinyo uma kudingeka.
| Izimo zezokwelapha ezingase zithinte imiphumela ye-ANA | |
|---|---|
| Izifo ezivame ukunikeza umphumela omuhle we-ANA (Izifo Ezizimele) | |
| |
| Ezinye izimo ezingase zibangele umphumela omuhle we-ANA | |
|
Uma ukuhlolwa kwe-ANA kutholakala ukuthi kuyiqiniso, kuzokwenzekani ngokulandelayo?
Uma ukuhlolwa kwe-ANA kutholakala ukuthi kuyiqiniso, udokotela wakho uzokwenza ezinye izivivinyo ezimbalwa zegazi ezikhethekile ukuthola ukuthi yisiphi isifo sokuzivikela komzimba esifanelana nezimpawu zakho. Ukuhlolwa kwe-ANA kuthi kuphela "kungase kube nenkinga." Uhlobo oluqondile lwaleyo nkinga lunqunywa ezinye izivivinyo ezifana nalezi.
- Ukuhlolwa kwe-Anti-dsDNA: Lokhu ukuhlolwa okusetshenziselwa ngqo ukuxilonga i-lupus.
- Ukuhlolwa kwe-anti-centromere: Lokhu kusiza ekuxilongeni i-scleroderma.
- Iphaneli ye-ENA: Lokhu kubheka izinhlobo eziningana ezahlukene zama-autoantibodies ngesikhathi esisodwa. Kungakunikeza isithombe esicacile sokuthi yisiphi isifo sokuzivikela komzimba onaso.
Ngakho-ke ungabi nokungabaza ngomphumela wakho we-ANA. Khuluma ngokukhululekile nodokotela wakho futhi ucacise ukuthi yini okufanele uyenze ngokulandelayo nokuthi iyiphi indlela yokwelapha okufanele uyithathe.
Umlayezo Wokuya Nawe Ekhaya
- Ukuhlolwa kwe-ANA ukuhlolwa kwegazi okulula okuhlola amaprotheni abizwa ngokuthi 'ama-autoantibodies' egazini ahlasela imizimba yethu.
- Umphumela wokuhlolwa omuhle awusho ukuthi unesifo ngaso sonke isikhathi. Abantu abaphilile nabo bangawuthola lo mphumela.
- Lokhu kuhlolwa kumane kuyithuluzi elilodwa udokotela wakho alisebenzisayo ukuthola isifo. Izimpawu zakho nezinye izivivinyo nazo zibalulekile.
- Udokotela wakho kuphela ongakunikeza iseluleko esingcono kakhulu mayelana nemiphumela yakho, ukuthi isho ukuthini, nokuthi yiziphi izinyathelo okufanele uzithathe ngokulandelayo, ngakho ungesabi ukukhuluma naye.
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