Ukhathele ukugula njalo ngenxa yomkhuhlane , ukukhwehlela, kanye nomkhuhlane? Ngezinye izikhathi sicabanga ukuthi, “O, umzimba wami ubuthakathaka.” Kodwa akusiyona njalo imbangela. Ngezinye izikhathi, isizathu salokhu kungaba ubuthakathaka ohlelweni lwethu lokuzivikela lomzimba, okungukuthi, uhlelo lokuzivikela. Namuhla, sizokhuluma ngesimo esinjalo, isifo esibizwa ngokuthi i-CVID , esingathinta kakhulu impilo yethu yansuku zonke.
Kuyini i-CVID?
Kalula nje, i-CVID (Common Variable Immunodeficiency) yisifo esibangelwa izakhi zofuzo esihlobene nesimiso somzimba wethu sokuzivikela. Siyingxenye yesifo esibizwa ngokuthi `isifo esiyinhloko sokuntuleka kwamasosha omzimba (PIDD)`.
Cabanga ngayo njengenqaba. Le nqaba inamasosha ayivikela ezitheni ezibizwa ngamagciwane . Lawa masosha yilokho esikubiza ngokuthi ama-antibodies kwezokwelapha. Umuntu one-CVID ukhiqiza la ma-antibodies ngamazinga aphansi kakhulu. Ngakho-ke, kwenzekani uma inani lamasosha enqabeni yethu lehla? Izitha zakwamanye amazwe, okungukuthi amagciwane, zingangena kalula emzimbeni futhi zibangele izifo .
Ngenxa yalokho, abantu abane-CVID bavame ukuba nezifo zendlebe , izifo zama-sinus , kanye nezifo zamaphaphu . Lesi simo siphinde sandise ingozi yezimo ezingathi sína, njengezinkinga zamathumbu, izifo zegazi kanye nezifo zokuzivikela komzimba , kanye nomdlavuza .
Ubani osengozini enkulu yokuthola i-CVID?
Uma kuqhathaniswa nezinye izifo zokuntuleka kwamasosha omzimba, i-CVID iyisifo esivame kakhulu. Ngokwesilinganiso, sithinta cishe umuntu oyedwa kwabangu-25,000.
Nakuba kungathinta noma ubani, kuvame kakhulu kubantu abadala. Nakuba i-CVID ingathinta izingane kanye nabantu abadala abasebasha, ivame ukutholakala lapho sebekhulile. Lesi sifo sivame ukutholakala phakathi kweminyaka engama-20 nengama-50 .
Kodwa-ke, ucwaningo lubonise ukuthi cishe abantu ababili kwabayi-10 abane-CVID batholakale benesifo sokuntuleka kwamasosha omzimba ebuntwaneni.
Yini ebangela i-CVID?
Eqinisweni, odokotela abakakazi kahle ukuthi yini ebangela iningi leziguli ze-CVID ukuthi zibe nalesi simo.
Kodwa-ke, cishe koyedwa kubantu abayi-10 abane-CVID, imbangela iwufuzo. Lokhu kusho ukuthi lesi simo singabangelwa ukuguquka kwezakhi zofuzo ku-DNA yakho . Kalula nje, kungenzeka ukuthi uzuze lesi simo kumama wakho, ubaba, noma elinye ilungu lomndeni.
I-CVID ingabangelwa futhi ukukhubazeka kwezakhi zofuzo ohlelweni lokuzivikela komzimba. Lokhu kukhubazeka kubangela ukuthi umzimba ukhiqize amazinga aphansi kakhulu ama-immunoglobulins, uhlobo lweprotheni olulwa namagciwane, futhi ikakhulukazi, ama-antibodies abizwa ngokuthi i-immunoglobulin G (IgG). Lokhu kwenza buthaka uhlelo lokuzivikela komzimba. Ngezinye izikhathi, lesi simo singakhula kamuva ekuphileni.
Ziyini izimpawu ze-CVID?
Izimpawu ze-CVID zingahluka kumuntu nomuntu. Abanye abantu banezimpawu ezincane, kanti abanye bangaba nezinzima kakhulu. Kuya ngokuthi amasosha omzimba wakho abuthaka kangakanani.
Ithebula elingezansi libonisa ezinye zezimpawu ezivame kakhulu ze-CVID.
| Isibonakaliso | Incazelo |
|---|---|
| Ukutheleleka kwesistimu yokuphefumula | Ukukhwehlela okuvamile nokuqhubekayo, ubunzima bokuphefumula, kanye nokutheleleka kwamaphaphu (okungaholela ezimweni ezifana ne-bronchitis noma i-pneumonia). |
| Ukutheleleka kwendlebe kanye ne-sinus | Ukutheleleka kwendlebe okuvamile kanye nokutheleleka kwama-sinus. |
| Izinkinga zesistimu yokugaya ukudla | Uhudo, isicanucanu, ukuhlanza, kanye nokwehla kwesisindo okungachazeki. |
| Amalunga kanye ne-spleen | Ukuvuvukala nobuhlungu emalungeni afana namadolo, izindololwane, kanye nezihlakala. Ubende obukhulu. |
| Ezinye izici | Izinkinga zokusebenza kwesibindi, ama-platelet aphansi egazini, kanye nokusabela okungavamile noma okunzima emithini yokugoma. |
Itholakala kanjani i-CVID?
Uma uhlala uthola izifo zendlebe, ama-sinus, noma amaphaphu, noma uma unempendulo engavamile emithini yokugoma evame ukunconywa, qiniseka ukuthi wazisa udokotela wakho.
Uma utshela udokotela wakho ngalezi zimpawu, angase asole i-CVID. Ukuze aqinisekise ukuxilongwa, uzobuza ngomlando wakho wezokwelapha kanye nomlando wezokwelapha womndeni wakho. Ngemuva kwalokho, bazo-oda ukuhlolwa kwegazi. Lokhu kuhlolwa kwegazi kungahlola ukuthi ama-antibodies omzimba wakho aphansi kangakanani nokuthi amasosha omzimba wakho asebenza kahle kangakanani.
Ngezinye izikhathi, udokotela wakho angakunikeza umuthi wokugomela esinye isifo futhi ahlole ukuze abone ukuthi amazinga omzimba wakho akhuphuka ngendlela evamile yini uma esabela.
Ingabe ikhona indlela yokwelapha i-CVID?
Akukho ukwelashwa kwe-CVID okwamanje. Kodwa ungakhathazeki. Ungasiphatha kahle lesi simo, uzivikele ezifweni, futhi uphile impilo evamile nenempilo.
Ukwelashwa okuyinhloko ukwelashwa kokufaka esikhundleni se-immunoglobulin (IgG) . Lokhu kuhilela ukunikeza isiguli ama-antibodies e-IgG, atholakala kubanikeli begazi abanempilo. Lokhu kwandisa izinga lama-antibodies emzimbeni wakho futhi kuqinise amasosha omzimba.
Lokhu kwelashwa kungatholakala ngezindlela ezimbili:
1. Indlela ye-IV: Njengesixazululo sikasawoti esifakwa emthanjeni (IV) kanye ngenyanga.
2. Indlela engaphansi kwesikhumba: Njengomjovo ngaphansi kwesikhumba kanye ngesonto noma njalo emavikini amabili.
Into ebaluleke kakhulu ukuthi lolu hlobo lokwelashwa kumele luthathwe impilo yonke.
Iningi labantu alibi nemiphumela emibi ebalulekile ngenxa yalokhu kwelashwa. Kodwa-ke, abanye bangase babe nekhanda elibuhlungu noma ukusabela kokungezwani komzimba. Khuluma nodokotela wakho ukuze uthole ukuthi yikuphi ukwelashwa okukulungele.
Ngaphezu kwalokho, uma unesifo, udokotela wakho uzokunikeza ama-antibiotic noma imithi yokulwa namagciwane ukuze akwelaphe.
Ezinye izinkinga ezingase zivele ngenxa ye-CVID
Ngenxa yokuthi amasosha omzimba awasebenzi kahle, abantu abane-CVID basengozini enkulu yokuthola ezinye izimo zezokwelapha ezingathi sína.
- Izifo ezizenzakalelayo: Lokhu kwenzeka lapho isimiso somzimba sokuzivikela sihlasela ngephutha amangqamuzana aso aphilile. Lokhu kungabangela izimo ezifana ne-'autoimmune hemolytic anemia' (ukubhujiswa kwamangqamuzana abomvu egazi aphilile), 'i-rheumatoid arthritis' (i-arthritis), kanye ne-'thrombocytopenia' (ama-platelet aphansi egazi).
- Umdlavuza: I-CVID yandisa ingozi yokuthola izinhlobo ezithile zomdlavuza, njenge-lymphoma noma umdlavuza wesisu.
- I-Bronchiectasis: Ukutheleleka kwamaphaphu okuvamile kungalimaza imigudu yomoya emaphashini futhi kubangele ukuthi ivuleke unomphela. Lokhu kungaholela ekukhwehleleni okuqhubekayo okune-mucus futhi kwenze kube nzima ukususa i-mucus.
- Ama-granuloma: Lawa amaqhubu amancane akhiwa ukuqongelela kwamangqamuzana amhlophe egazi. Avame ukubonakala emaphashini, esikhumbeni, noma kwezinye izitho zomzimba.
Umlayezo Wokuya Nawe Ekhaya
- I-CVID yisifo sofuzo esenza buthaka amasosha omzimba ngenxa yamazinga aphansi ama-antibodies akhiqizwa umzimba.
- Ukutheleleka njalo kwendlebe, ama-sinus, namaphaphu kuyizimpawu eziyinhloko.
- Uma wena noma othile omaziyo enalezi zimpawu, xhumana nodokotela ngokushesha ukuze uthole iseluleko.
- Nakuba i-CVID ingelapheki ngokuphelele, ingaphathwa kahle ngokwelashwa ngama-antibody impilo yonke (i-IgG therapy).
- Uma une-CVID, kubaluleke kakhulu ukugcina imikhuba emihle yokuhlanzeka, njengokugeza izandla zakho njalo, ukuze uzivikele emagciwaneni.
I-CVID, Ukuntuleka Kwamasosha omzimba Okuvamile, ukuzivikela komzimba, ukugula okuvamile, izifo, ama-antibodies, ukwelashwa kwe-IgG
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