Momma yensua "bile retention" anaa cholestasis ho ade.

So woate “bile siw” anaa “akisikuru” ho asɛm pɛn? Ebia woahu sɛ nnipa binom ani ne wɔn honam ani yɛ kɔkɔɔ. So woasusuw nea nneɛma yi yɛ ankasa ne nea enti a ɛba no ho pɛn? Ɛnnɛ yɛrebɛka tebea a ɛte saa ho asɛm. Wɔ aduruyɛ mu frɛ no cholestasis. Mma ɛnhaw wo, ma yɛnkyerɛkyerɛ mu tiawa.

Dɛn ne Cholestasis?

Sɛ yɛbɛka no tiawa a, cholestasis yɛ bere a bile a efi wo mmerɛbo mu no brɛ ase anaasɛ egyae koraa. Fa no sɛ adwumayɛbea ketewaa bi a ɛwɔ yɛn nipadua mu. Ɛma wonya ade bi a wɔfrɛ no bile . Saa bile yi boa yɛn ma yɛyam aduan a yedi, titiriw nnuan a srade wom.

Mmɛn no na ɛyɛ saa bile yi na ɛde kɔ yɛn aduan mu ntini nketenkete bi a wɔfrɛ no bile ntini mu . Saa bile ntini yi bi wɔ mmerɛbo no mu (intrahepatic ducts) na ebi nso wɔ mmerɛbo no akyi (extrahepatic ducts). Saa ntini nhyehyɛe yi na ɛka mmerɛbo, akisikuru, dwensɔtwaa , ne dwensɔtwaa ketewa bom. Eyinom nyinaa bom yɛ biliary nhyehyɛe no .

Afei susuw ho hwɛ, sɛ biribi siw anaasɛ esiw wɔ baabi wɔ saa bile duct nhyehyɛe yi mu a, dɛn na ɛba? Ɛte sɛ nsu paipu a asiw. Bile ntumi nkɔ yiye. Afei saa bile yi fi ase boaboa ano wɔ bile ntini ne akwaa a ɛfa ho te sɛ mmerɛbo no mu. Eyi betumi asɛe saa ntini ahorow no na asiw wɔn dwumadi kwan. Ɛnyɛ ɛno nko, na mmom saa mogya a aboaboa ano yi fi ase tu kɔ mogya no mu nkakrankakra. Eyi pira nipadua no na ɛyɛ awuduru . Eyi betumi de yare no ho sɛnkyerɛnne a ɛnyɛ dɛ aba, na bere kɔ so no, ebetumi de nyarewa ahorow aba. Ɛtɔ mmere bi a, cholestasis betumi ayɛ bere tiaa mu ɔhaw, anaasɛ ebetumi ayɛ ɔhaw a ɛkɔ soro nkakrankakra na ɛkɔ so.

Eyi ka wo nipadua dɛn?

Cholestasis betumi aka wo nipadua wɔ akwan horow so.

Nsunsuanso a ɛba bere tiaa mu:

Ade a edi kan a ɛka no ne akwaa a ɛwɔ wo biliary system no mu. Nsu a ɛboaboa ano no betumi ama mmerɛbo, akisikuru, dwensɔtwaa, anaa bile ntini ahonhon na ayɛ ɔfe . Eyi betumi de sɛnkyerɛnne ahorow te sɛ yafunu mu yaw ne akisikuru aba. Ɛma asiane a ɛwɔ hɔ sɛ obi benya ɔyare mmoawa no nso yɛ kɛse.

Afei nso, esiane sɛ dwensɔtwaa ketewaa no nnya bile a ɛdɔɔso nti, srade a ɛwɔ aduan a wudi mu no ntumi nwe yiye. Eyi betumi ama obi ho ayɛ no yaw, aduan a ontumi nnya, ne akisikuru.

Nsunsuanso a ɛtra hɔ kyɛ:

Sɛ tebea yi kɔ so a, ɔhaw pii betumi asɔre.

• Nsu a ɛboaboa ano wɔ mogya no mu no betumi ama obi anya jaundice , a ɛyɛ aniwa ne honam ani yɛ kɔkɔɔ, ne nsu a ɛyɛ tuntum.
• Ebia nnipa binom benya ɛyaw a emu yɛ den (a ɛyɛ akisikuru) . Nea enti a ɛte saa ne sɛ bile nkyene a ɛwɔ mogya no mu no kanyan ntini ahorow no.
• Sɛ akwaa ahorow te sɛ mmerɛbo no ho hyehyee bere tenten a, ebetumi ama wanya akuru na wahwere ne dwumadi daa. Wɔsan frɛ eyi sɛ akisikuru .
• Vitamin a srade wom te sɛ vitamin A , D, E, ne K , nipadua no ntumi nnye no yiye. Eyi betumi ama obi anya aduan pa a wonnya nni. Eyi betumi ama onyin ayɛ mmerɛw, titiriw wɔ mmofra nkumaa mu.

Titiriw no, kae!

Awo mu cholestasis bere a nyinsɛn no ma asiane a ɛwɔ hɔ sɛ ɛna no ne akokoaa no nyinaa betumi anya nsɛnnennen a ɛde ne nkwa to asiane mu no yɛ kɛse. Eyinom bi ne preeclampsia, awo a ɛba ntɛm, ne awo a wawu. Enti, sɛ wuhu saa sɛnkyerɛnne ahorow yi wɔ nyinsɛn mu a, ɛho hia sɛ wohwehwɛ aduruyɛfo afotu ntɛm ara.

Dɛn ne ade titiriw nti a ɛte saa?

Nneɛma pii na ɛde cholestasis ba. Mpɛn pii no, ɔhaw ahorow abien na ɛwɔ hɔ:

Dɛn ne sɛnkyerɛnne ahorow a ɛkyerɛ sɛ obi anya cholestasis?

Nsɛnkyerɛnne ahorow pii wɔ hɔ a wɔtaa hu wɔ tebea yi mu:

• Jaundice: Wo honam ani a ɛyɛ kɔkɔɔ ne w’ani fitaa no taa yɛ sɛnkyerɛnne a edi kan a ɛkyerɛ sɛ wo mmerɛbo no ntumi nyɛ adwuma yiye. Eyi fi bile a ɛboaboa ano wɔ mogya no mu. Ne titiriw no, aduru bi a wɔfrɛ no bilirubin a ɛwɔ bile mu na ɛma kɔla kɔkɔɔ yi ba. Ɛtɔ da bi a, bilirubin nso pue kɔ nsuo no mu, na ɛtumi dane nsuo no kɔla kɔkɔɔ/biribiri tuntum.
• Poop a ne kɔla yɛ hann: Nea enti a ɛte saa ne sɛ bile ntumi nkɔ dwensɔtwaa no mu yiye, na ɛno betumi ama nsakrae aba nsu mu. Sɛ bile nni hɔ a wɔde bɛyam srade a, srade no ne nsu no kɔ. Saa poop yi yɛ fitaa, ɛyɛ dɔte kɔla. Afei nso, saa kɔla a ɛyɛ hare yi fi bilirubin a enni mu (mpɛn pii no, nsu a ɛyɛ bruu esiane bilirubin nti). Ebia eyinom bɛsensɛn nsu mu na ayɛ hua a ano yɛ den.
• Pruritus: Eyi yɛ sɛnkyerɛnne foforo a wɔtaa hu wɔ cholestasis mu. Ɛyaw a ɛbata bile ho no ba bere a bile nkyene anaa bile acid boaboa ano wɔ mogya no mu na ɛkanyan ntini a ɛwɔ akyi no. Saa akisikuru yi mma akisikuru biara mma. Nnipa binom ani gye saa bile nkyene yi ho kɛse. Nnipa binom ntumi nyɛ wɔn yaw pii, bere a afoforo nso wɔ wɔn yaw pii. Ebia ɛyaw no bɛyɛ kɛse wɔ nsateaa, nan ase, ne akwaa so, na nipadua no nyinaa betumi ayɛ no yaw.

Wɔ sɛnkyerɛnne atitiriw yi akyi no, sɛnkyerɛnne afoforo betumi aba a egyina nea ɛde cholestasis ba so.

• Yafunu mu yaw
• Akisikuru ne ɔfe
• Ɔbrɛ

Wobɛyɛ dɛn ahu eyi?

Sɛ wowɔ cholestasis ho sɛnkyerɛnne ahorow a, ade a oduruyɛfo bɛyɛ ne sɛ ɔbɛsɔ wo mogya bi ahwɛ.

• Mogya mu nhwehwɛmu:Eyi hwɛ sɛ bilirubin ne bile nkyene dodow kɔ soro anaa. Ɛsan nso hwɛ sɛ srade a ɛwɔ mogya mu ne mmerɛbo mu enzyme ahorow bi te sɛ gamma-glutamyl transferase (GGT) ne alkaline phosphatase (ALP) akɔ soro anaa. Eyinom betumi ama yɛanya nea ɛde yare no ba no ho adwene bi.
• Mfoniniyɛ mu nhwehwɛmu: Sɛ mogya mu nhwehwɛmu kyerɛ sɛ ɔyare a, ade a edi hɔ a ɛsɛ sɛ woyɛ ne sɛ wobɛyɛ mfoninitwa nhwehwɛmu de ahwɛ wo biliary system no. Eyinom betumi afi ase denam nhwehwɛmu a ɛnyɛ den a ɛnyɛ nea wɔde hyɛ nipadua mu te sɛ yafunu mu ultrasound anaa yafunu mu CT scan so. Eyinom betumi ahwehwɛ honam fam akwanside ahorow wɔ bile ntini no mu ne akwaa ahorow no a ɛho ahonhon.
• Nhwehwɛmu a wɔde hwehwɛ nneɛma mu: Nneɛma bi a ɛde cholestasis ba no hwehwɛ sɛ wɔyɛ emu nhwehwɛmu na ama wɔahu nea ɛde ba no na wɔasa. Ebia ɛho behia sɛ oduruyɛfo no hwehwɛ bile ntini no mu anaasɛ ɔfa ntini ketewaa bi fi mmerɛbo no mu (mrɛbo mu nhwehwɛmu) de yɛ nhwehwɛmu wɔ aduruyɛdan mu. Wɔ ERCP (Endoscopic Retrograde Cholangiopancreatography) , mu no, nnuruyɛfo betumi ahwehwɛ ɔhaw ahorow a ɛwɔ ntini a ɛma mogya tu no mu na wɔasa.

Ɔkwan bɛn so na wɔsa?

Ayaresa a wɔde sa cholestasis no gyina nea ɛde ba no so.

• Nneɛma a ɛde ba denneennen: Wobetumi asa nneɛma bi a ɛde ba no ntɛm ara. Nnuru a ɛde ɔhaw no reba no, wobetumi de nnuru foforo asi ananmu. Wobetumi de nnuru a ekum ɔyare mmoawa anaa nnuru a ekum ɔyare mmoawa ama ɔyare mmoawa. Wobetumi de endoscopic akwan te sɛ ERCP ayi bile duct a ɛsiw no afi hɔ.
• Nneɛma a ɛde mmerɛbo mu yare ba a enni sabea: Ebetumi ayɛ den sɛ wɔbɛsa nneɛma a enni sabea a ɛde mmerɛbo mu yare ba. Nyarewa bi nni aduru a ɛtra hɔ daa, na wɔrentumi nsan mmerɛbo mu akuru (cirrhosis) no. Nanso, asetra mu nsakrae te sɛ aduan, apɔw-mu-teɛteɛ, ne nsa a wɔkwati betumi aboa ma wɔadi mmerɛbo mu nyarewa pii a ɛkɔ so no so. Saa bere yi de, wo duruyɛfo no de n’adwene besi wo tebea no mu nsunsuanso bɔne a ɔbɛsa so.

Ebia ayaresa ahorow no bi ne:

• Aduan pa: Nsakrae a wɔyɛ wɔ aduan mu ne aduannuru a wɔde ma no betumi aboa ma wɔasiw aduan pa a wonnya nni ne vitamin a wonnya nni ano.
• Ursodeoxycholic acid a wɔde yɛ aduru:Wɔtaa de saa aduru yi di dwuma de tew akisikuru mu abo, nanso ɛtɔ mmere bi nso a ebetumi aboa wɔ cholestasis ho denam bile a ɛma mogya mu nsu yɛ kɛse na ɛtew nkɛntɛnso a akisikuru nkyene a ɛboro so wɔ mogya no mu no so.
• Naltrexone: Ɛtɔ mmere bi a wɔde saa opioid a ɛko tia yi di dwuma de sa ɛyaw a emu yɛ den. Ɛyɛ adwuma denam ntini akwan a bile acid a ɛwɔ mogya no mu kanyan no a esiw ano no so.
• Cholestyramine: Saa aduru a ɛtew srade so yi kyekyere srade ne bile nkyene a ɛwɔ dwensɔtwaa no mu, na ɛma emu pii fi nsu mu.