Mifepristone nnuru a wɔde sa Cushing yare no? Momma yɛnka eyi ho asɛm!

So wowɔ Cushing Syndrome a ɛyɛ wo yare ? Anaasɛ obi a wunim no wɔ saa tebea yi? Nea ɛba wɔ asɛm yi mu ne sɛ yɛn nipadua no yɛ cortisol hormone pii sen sɛnea ɛho hia, na ɛma asikre dodow a ɛwɔ mogya mu , kyerɛ sɛ, glucose, kɔ soro. Enti, nnuru a nnuruyɛfo kamfo kyerɛ wɔ mmere te sɛ eyi mu no mu biako ne Mifepristone. Ɛnnɛ, yɛbɛka Mifepristone nnuru yi ho asɛm kɔ akyiri.

Aduru bɛn na Mifepristone yɛ?

Sɛ yɛbɛka no tiawa a, wɔde Mifepristone nnuru titiriw di dwuma de hwɛ mogya mu glucose dodow so wɔ Cushing’s Syndrome , tebea a ɛba bere a hormone cortisol a ɛwɔ wo nipadua mu no kɔ soro dodo no mu.

So wunim sɛ saa hormone a wɔfrɛ no cortisol yi ho hia ma yɛn nipadua no? Sɛ yɛhaw a, yɛn nipadua siesie ne ho sɛ ɛbɛfa saa hormone yi so adi ho dwuma. Sɛ nhwɛso no, sɛ nipadua no hia ahoɔden pii ntɛm ara a, saa cortisol yi boa ma asikre pii kɔ mogya no mu. Nanso, sɛ eyi kɔ soro a wontumi nni so a, ɔhaw ahorow sɔre. Mifepristone nnuru brɛ cortisol hormone no nkɛntɛnso ase, na ɛnam so ma asikre dodow a ɛwɔ mogya mu no so tew.

Ɛtɔ mmere bi a, nnuruyɛfo betumi akyerɛw saa aduru yi ama wɔ tebea afoforo ho. Enti, sɛ wunnim nea aduru yi yɛ ma ankasa a, ɛbɛyɛ papa sɛ wubebisa wo duruyɛfo anaa nnuruyɛfo a ɔwɔ nnurutɔnbea a wofa w’aduru no. Wɔde edin Korlym nso frɛ saa aduru yi wɔ gua so .

Nneɛma bɛn na ɛsɛ sɛ meka kyerɛ oduruyɛfo no ansa na manom saa aduru yi?

Ansa na wubefi ase de Mifepristone aduru adi dwuma no, nneɛma bi wɔ hɔ a ɛho hia a ɛsɛ sɛ woka kyerɛ wo duruyɛfo no ampa . Efisɛ, ɛsɛ sɛ nnipa a wɔwɔ ayaresa tebea horow bi anaa wɔn a wɔnom nnuru afoforo no hwɛ yiye kɛse bere a wɔde Mifepristone rema no. Hwɛ sɛ nea edidi so yi fa wo ho anaa:

• So wowɔ mogyatɔw yare bi ?
• So wowɔ kokoram mprempren anaasɛ woreyɛ ho ayaresa?
• So wowɔ adwenemyare bi te sɛ adwenemhaw ?
• So wowɔ asikreyare foforo a ɛne Cushing yare no nni abusuabɔ?
• Koma mu yareSo wowɔ komayare?
• So wowɔ mogya mmoroso ?
• So wowɔ mmerɛbo mu yare bi?
• So nnuruyɛfo aka akyerɛ wo sɛ potassium dodow a ɛwɔ wo mogya mu no sua?
• So wɔayɛ wo akwaa foforo pɛn?
• So mprempren worenom nnuru a wɔde yɛ steroid te sɛ dexamethasone anaa prednisone?
• So wowɔ mogya a ɛba wo awotwaa mu a wontumi nkyerɛkyerɛ mu?
• So woanya mifepristone, nnuru foforo biara, aduan, aduan a wɔde yɛ nneɛma, anaa nneɛma a wɔde siw ano ho adwene pɛn?
• So mprempren worebɔ mmɔden sɛ wubenyinsɛn? Anaasɛ woanyinsɛn dedaw?
• So woyɛ ɛna a ɔma nufu? (Nufu a wɔde ma) .

Sɛ wowɔ tebea bi a ɛte sɛɛ a, ɛbɛyɛ papa sɛ wobɛka ho asɛm akyerɛ wo duruyɛfo a womfa biribiara nsie .

Ɔkwan bɛn so na ɛsɛ sɛ mede saa aduru yi di dwuma?

Ɛsɛ sɛ wɔde Mifepristone aduru yi ka nsu ho. Ɛho hia yiye sɛ wobɛnom saa aduru yi bere koro mu da biara , sɛnea wɔakyerɛ wɔ nnuru a wɔakyerɛw ama wo no krataa so no. Mmu , nsɛe, anaa nwe saa aduru yi. Fa nsu mene tablet no nyinaa.

Ade foforo a ɛho hia ne sɛ ɛsɛ sɛ wɔde saa aduru yi ka aduan ho. Afei nso, mfa saa aduru yi nka bobe nsu ho esiane biribiara nti. Ɛsɛ sɛ wokɔ so de saa aduru yi di dwuma sɛnea wɔakyerɛ wo no kosi sɛ wo duruyɛfo bɛka akyerɛ wo sɛ gyae.

Sɛ nnurutɔnbea no ma wo saa aduru yi a, wɔbɛma wo kratawa bi a akwankyerɛ titiriw a ɛfa aduru yi ho wom, a wɔfrɛ no MedGuide . Ɛho hia paa sɛ wobɛkenkan na woate MedGuide krataa yi ase yie berɛ biara a wobɛnom aduru no, ne berɛ a wobɛsan ahyɛ no ma.

Sɛ wode saa aduru yi rema mmofra nkumaa a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa afa ho, efisɛ ebia ebehia sɛ oduruyɛfo hwɛ ne hwɛ titiriw.

Sɛ wonom boro so a, dɛn na wobɛyɛ?

Sɛ wususuw sɛ woanom aduru yi dodo a, frɛ beae a ɛbɛn awuduru a wɔde siw ano anaa ɔman ayaresabea dan a wɔhwɛ wɔn a wɔwɔ ayaresa a egye ntɛmpɛ mu ntɛm ara na woanya afotu.

Kae nso: Wɔakyerɛw saa aduru yi ama wo nkutoo. Mfa mma w’adamfo anaa w’abusua muni bi esiane biribiara nti, sɛ mpo wɔn nso wɔ sɛnkyerɛnne koro no ara sɛ wo de a.

Sɛ wopa nnuru dodow bi a, dɛn na ɛsɛ sɛ woyɛ?

Sɛ wo werɛ fi sɛ wobɛnom Mifepristone aduru da bi a, fa no bere a wokae ara pɛ. Nanso, sɛ ɛkame ayɛ sɛ bere adu sɛ wobɛma wo dodow a edi hɔ bere a wokae a, twa dodow a woayera no so na fa wo dodow a edi hɔ no wɔ bere a woahyɛ da ayɛ no mu. Mfa nnuru mmɔho abien anaa nea ɛboro so da, kyerɛ sɛ, fa dodow a woayera ne nea anka ɛsɛ sɛ wonom bere koro mu no nyinaa. Saa a wɔyɛ no ma asiane a ɛwɔ hɔ sɛ wobenya ɔhaw ahorow no yɛ kɛse.

Nnuru afoforo bɛn na ɛnsɛ sɛ wɔde ka aduru yi ho?

Sɛ mprempren worenom nnuru a edidi so yi mu biara a, mfa nka Mifepristone ho da. Eyinom betumi de nkitahodi a anibere wom na asiane wom a ebetumi de nkwa ato asiane mu aba:

• Nnuru bi a wɔde sa fungal yare, sɛ nhwɛso no, fluconazole, ketoconazole, ne posaconazole.
• Wɔkyerɛw nnuru bi ma sɛ wɔmfa mma mogya mu srade so tew, sɛ nhwɛso no, lovastatin ne simvastatin.
• Cisapride na ɔkyerɛwee
• Cyclosporine a wɔde di dwuma
• Dronedarone a wɔfrɛ no Dronedarone
• Sɛ nhwɛso no, ergot alkaloids, dihydroergotamine ne ergotamine.
• Fentanyl a wɔde yɛ aduru
• Pimozide a wɔde yɛ nnuru
• Quinidine a wɔde ma
• Sirolimus a wɔfrɛ no sirolimus
• Tacrolimus a wɔde di dwuma
• Thioridazine a wɔde ma

Saa nsɛm a wɔahyehyɛ yi nyɛ nea edi mũ, enti ɛho hia yiye sɛ woka nnuru biara a wobɛnom, vitamin mpo ho asɛm kyerɛ wo duruyɛfo.

Nnuru afoforo ne nneɛma a ebia ɛne wɔn ho wɔn ho di nkitaho

Nnuru ne nneɛma afoforo wɔ hɔ a ebetumi ne Mifepristone adi nkitaho, enti ɛyɛ papa sɛ wubehu eyinom nso:

• Nnuru ahorow bi a ekum ɔyare mmoawa, sɛ nhwɛso no clarithromycin, erythromycin, telithromycin.
• Wɔde nnuru bi a ekum ɔyare mmoawa ma ma obi nya HIV anaa mmerɛbo mu nyarewa te sɛ hepatitis.
• Nnuru a wɔde sa ntini mu yare te sɛ akisikuru, sɛ nhwɛso no carbamazepine, phenytoin, ne phenobarbital.
• Nnuru bi a ɛmma mogya ntumi nkɔ, sɛ nhwɛso no, warfarin.
• Conivaptan a wɔde yɛ aduru
• Grapefruit nsuo – Sɛnea yɛadi kan aka no, eyi yɛ biribi a ɛnyɛ papa sɛ wobɛnom bere a worenom Mifepristone.
• Nnuru a wɔde siw awo ano a ahoɔdennuru wom, nnuru a wɔde twitwiw nipadua no, nnuru a wɔde hyɛ nipadua mu ne mfiri a hormone wom.
• Itraconazole a wɔde ma
• Nnuru a wɔde sa adwene mu tebea horow te sɛ adwenemhaw anaa dadwen a emu yɛ den.
• Wɔde nnuru a wɔde kum nnubɔne bi ma sɛ nnuru a wɔde kum ɛyaw.
• Nnuru afoforo a ebetumi ama koma no ayɛ adwuma yiye, te sɛ nea ɛma QT ntam kwan no kyɛ.
• Repaglinide a wɔde yɛ aduru
• Rifabutin, Rifampin, Rifapentine, ne nea ɛwɔ nipadua no mu.
• St. John’s wort yɛ nhabannuru a wɔde ma.
• Steroid nnuru te sɛ prednisone anaa cortisone.
• Thyroid hormone ahorow a ɛma nipadua no yɛ adwuma.
• Voriconazole a wɔde ma.

Ebia saa nsɛm a wɔahyehyɛ yi nyɛ nea ɛfa ne nyinaa ho. Enti, hwɛ hu sɛ wobɛka nnuru, nhabannuru, nnuru a wɔkyerɛw ma wo, ne nnuru a wɔde ka aduan ho a worenom nyinaa ho asɛm akyerɛ wo duruyɛfo . Afei nso, sɛ wonom sigaret, wonom nsa, anaa wode nnubɔne a mmara mma ho kwan di dwuma a, ka kyerɛ wo duruyɛfo. Eyinom betumi ne Mifepristone a worenom no adi nkitaho.

Nneɛma bɛn na ɛsɛ sɛ yɛhwɛ yiye wɔ ho bere a yɛrenom aduru yi?

Bere a worenom Mifepristone no, ɛho behia sɛ wokɔ wo duruyɛfo nkyɛn kɔhwɛ wo daa de hwɛ w’akwahosan. Ebia wo duruyɛfo nso bɛkamfo akyerɛ wo sɛ wonyɛ mogya ho adwuma bi.

Saa aduru yi betumi aka asikre dodow a ɛwɔ mogya mu. Sɛ wowɔ asikreyare a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa ansa na woayɛ nsakrae biara wɔ w’aduan anaa asikreyare aduru dodow a wode di dwuma no mu.

Fa akwankyerɛ titiriw kratasin a ɛfa aduru yi ho a wɔfrɛ no MedGuide no sie yiye. Sɛ wuhia ayaresa a egye ntɛmpɛ a, fa MedGuide kratasin no kyerɛ aduruyɛ kuw no. Ka kyerɛ wɔn nso sɛ worenom Mifepristone.

Nneɛma a ɛsɛ sɛ wɔhwɛ yiye wɔ ho titiriw ma mmea:

• Ɛsɛ sɛ woyɛ nyinsɛn mu nhwehwɛmu de hwɛ sɛ woanyinsɛn anaa ansa na woafi Mifepristone aduru yi ase. Nnyinsɛn bere a worenom aduru yi anaa ɔsram biako bere a woagyae aduru no akyi.
• Sɛ woreyɛ nhyehyɛe sɛ wubenyinsɛn anaa wususuw sɛ ebia woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara. Saa aduru yi betumi de nsunsuanso bɔne a emu yɛ den aba akokoaa a ɔhyɛ yafunu mu. Bisa wo duruyɛfo ma ɔmma no nsɛm pii.
• Ɛsɛ sɛ wode awo ano aduru a etu mpɔn di dwuma bere a worenom Mifepristone no. Awo ano aduru a wɔmfa hormone nni dwuma ye sen biara bere a wɔrenom aduru yi ne ɔsram biako bere a wɔagyae aduru no akyi. Wo ne wo duruyɛfo nkasa mfa ɔkwan pa a wobɛfa so asiw nyinsɛn ano ho. Sɛ wususuw sɛ woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara.

Wɔ ɛnanom a wɔma wɔn nufu fam no: Mma wo ba no nufu bere a worenom Mifepristone aduru yi.

Dɛn ne aduru yi mu nsunsuanso bɔne a ebetumi afi mu aba?

Te sɛ nnuru nyinaa no, Mifepristone betumi de ɔhaw ahorow bi aba. Nneɛma bɔne bi wɔ hɔ a sɛ ɛba a, ɛsɛ sɛ woka kyerɛ wo duruyɛfo ntɛm ara. Wɔne:

• Nneɛma a ɛma obi ho yɛ no hyew: Honam ani akisikuru, ɛyaw, akisikuru, anim, anofafa, tɛkrɛma, anaa menewa a ɛho ahonhon. Eyinom betumi ayɛ nea asiane wom.
• Koma mu nnyigyei sesa: koma bɔ ntɛmntɛm anaasɛ koma bɔ ntɛmntɛm, adwenemhaw, te nka sɛ wo ho ayɛ wo hyew anaasɛ wo ti ayɛ hare, koko mu yaw, ɔhome a ɛyɛ den.
• Wɔ mmea fam: Brayɛ a ɛnkɔ so daa anaasɛ mogya a ɛtɔ (spotting) a ɛyɛ soronko bere a wɔrekɔ brayɛ mu.
• Nsɛnkyerɛnne a ɛkyerɛ sɛ adrenal gland ntumi nyɛ adwuma yiye: akisikuru, ɔfe, aduan ho akɔnnɔ a ɛyera, mmerɛwyɛ anaa ɔbrɛ a ɛyɛ soronko, adwenemhaw.
• Potassium dodow a ɛba fam wɔ mogya mu ho sɛnkyerɛnne: ntini mu yaw anaa akisikuru, mmerɛwyɛ anaa ɔbrɛ a ɛyɛ soronko, koma a ɛbɔ ntɛmntɛm anaasɛ ɛnyɛ daa, akisikuru.

Mpɛn pii no, nsunsuanso bɔne a wɔabobɔ din wɔ ase ha no nyɛ aniberesɛm, nanso sɛ ɛkɔ so anaasɛ ɛhaw wo a, ka kyerɛ wo duruyɛfo:

• Adwene a ɛyɛ basaa
• Ɔbrɛ
• Tipaeɛ
• Nkwaa mu yaw
• Aduan ho akɔnnɔ a ɛyera
• Abofono
• Asen, nsa, anaa anan a ɛho ahonhon.

Saa nsɛm a wɔahyehyɛ yi nka Mifepristone ho nsunsuanso bɔne a ebetumi aba nyinaa ho. Sɛ wuhu sɛnkyerɛnne biara a ɛyɛ soronko a, ka kyerɛ wo duruyɛfo. Wubetumi nso abɔ nea ɛde ba no ho amanneɛ akyerɛ U.S. Aduan ne Nnuru Dwumadibea (FDA) wɔ 1-800-FDA-1088.

Ɔkwan bɛn so na ɛsɛ sɛ mede m’aduru sie?

Fa Mifepristone aduru yi sie baabi a ahobammɔ wɔ a mmofra nkumaa ne afieboa ntumi nkɔ hɔ . Fa sie wɔ dan mu hyew, digrii Celsius 20 kosi 25 (digrii Fahrenheit 68 kosi 77). Hwɛ da a aduru no bɛtwam na fa aduru biara a ne bere atwam nni dwuma da. Tow gu yiye.

Wobɛyɛ dɛn atow nnuru a ɛho nhia bio anaasɛ ne bere atwam a ɛnsɛe nneɛma a atwa yɛn ho ahyia no gu?

• Nnurutɔnbea anaa ayaresabea ahorow bi wɔ nhyehyɛe ahorow a wɔde san fa nnuru. Sɛ ɛbɛyɛ yiye a, fa w’aduru no kɔ mmeae yi biako. Wubetumi ahu eyi ho nsɛm pii wɔ wo nnurutɔnbea anaa mpɔtam hɔ ɔmanfo akwahosan ho nhwehwɛmubea.
• Sɛ ɔkwan biara nni hɔ a wobɛfa so asan de a, hwɛ nnuru a wɔde ahyɛ mu anaa akwankyerɛ a ɛwɔ mu no mu hwɛ sɛ ɛsɛ sɛ wɔtow gu nwura mu anaasɛ wɔhohoro gu tiafi mu anaa. Sɛ wunnim a, bisa wo duruyɛfo anaa nnuruyɛfo.
• Sɛ wubetumi atow agu nwura mu a, yi nnuru no fi toa anaa packet no mu, fa fra yiye ne mpataa nwura a wɔde adi dwuma, dɔte bi, kɔfe a wɔayam, anaa nneɛma foforo a ɛte saa a wompɛ. Afei, fa saa afrafrade yi gu polythene kotoku anaa plastic a wotumi san to mu mu, kata so yiye, na tow gu nwura mu.

Nea etwa to no, nneɛma a ɛsɛ sɛ yɛkae

Okay, enti seesei woate aseɛ sɛ Mifepristone yɛ aduru a ɛho hia a ɛbɛtumi aboa ama asikre dodoɔ a ɛwɔ mogya mu no so ama obi te sɛ wo a ɔwɔ Cushing Syndrome. Nanso wuhu nso sɛ nneɛma pii wɔ hɔ a ɛsɛ sɛ wohwɛ yiye wɔ ho kɛse bere a wode redi dwuma no.

Titiriw no, ɛho hia yiye, yiye sɛ wobɛka nnuru afoforo a worenom ne nyarewa afoforo a wowɔ ho asɛm akyerɛ wo duruyɛfo no pefee, sɛ wobɛnom aduru no sɛnea oduruyɛfo no ka no pɛpɛɛpɛ, wɔ bere ne dodow a wɔakyerɛw ama wo no mu, sɛ wuhu nea ebetumi afi mu aba, na woahwɛ yiye titiriw wɔ nyinsɛn ne awo ano aduru ho.

Sɛ wowɔ nsɛmmisa anaa adwenem naayɛ bi wɔ aduru yi ho a, ntwentwɛn wo nan ase da sɛ wobɛka akyerɛ wo duruyɛfo anaa nnuruyɛfo a ɔwɔ nnurutɔnbea hɔ sɛ onsiesie. Kae sɛ w’akwahosan ho hia wo paa!

` Mifepristone, Cushing yare, cortisol, asikre a ɛwɔ mogya mu, adrenal gland, nnuru a ɛne ne ho di nkitaho, nea efi mu ba