Ðe wòdze abe ʋuka yeyewo le wɔwɔm ɖe wò ŋku me enea? Ðe míaƒo nu tso ŋkua ƒe ʋuka yeye sia ŋua?

Ɣeaɖewoɣi la, kuxi siwo míele mɔ kpɔm na o doa mo ɖa le míaƒe ŋkuwo ŋu, alo? Kasia, míaƒe ŋkuwo meganɔa dzo dam o, alo míaƒe ŋkuwo biãna henɔa veve sem. Ðewohĩ nɔnɔme aɖe le megbe na nusiawo si ŋu míese nu geɖe tsoe o. Nɔnɔme mawo dometɔ ɖekae nye ŋku ƒe ʋuka yeyewo, alo ʋuka yeyewo ƒe wɔwɔme le ŋkua me.

Nukae ʋuka yeyewo dzɔna le ŋkua me? (Ŋkua ƒe Ʋuka Yeyewo ƒe Ʋuka) .

Kpuie ko la, ɣeyiɣi sia mee ʋuka yeyewo va le ŋkua me. Gake ʋuka siawo tsina le teƒe siwo mele be woatsi o, le mɔ siwo mele be woatsi o nu, eye ɣeaɖewoɣi la, wogbɔa eme . Wotsina abe gbewo ene. Ka yeyewo hã ate ŋu adzɔ le ʋuka yeye siawo dome. Ɣemaɣie nukpɔkpɔ dzea ŋusẽkpɔkpɔ gɔme.

Esiae nye nusi míeyɔna le atikewɔwɔ me be ``Neovascularization``, ʋuka yeye siwo womedi o ƒe wɔwɔme le ŋkua me. Esia ate ŋu ana ŋkua naxɔ abi eye abi nanɔ ŋkua me, si ate ŋu ana ŋkua naɖiɖi alo wòabu keŋkeŋ mlɔeba . Zi geɖe la, abi alo dɔléle si yia edzi gbɔe nɔnɔme sia tsona .

Afikae ʋuka yeye siawo ate ŋu adzɔ le le ŋkua me?

Azɔ mina míakpɔ ŋku ƒe akpa siwo dzi ʋuka yeye siawo ate ŋu akpɔ ŋusẽ ɖo. Ŋku nye ŋutinu si gɔme sese sesẽ ŋutɔ eye wòle bɔbɔe ŋutɔ.

• Choroid: Esia le ŋkua ƒe ŋkume kple ŋku ƒe akpa si le ɣie, dome. Afi siae ʋuka siwo naa ʋu naa ŋkua ƒe akpa gãtɔ le.
• Retina: Afi siae kekeli si gena ɖe ŋkua me trɔna zua elektrikŋusẽ ƒe dzesiwo heɖonɛ ɖe ahɔhɔ̃a me. Esiae na míete ŋu kpɔa nuwo.
• Macula: Esia le ŋkume ƒe titina. Ekpena ɖe mía ŋu míekpɔa nu siwo le mía ŋkume tẽ la nyuie.
• Iris: Esiae nye ŋkua ƒe akpa si naa eƒe amadede. Kplɔ̃ yibɔ sue si le titina, si nye ŋkuvi , hã le afisia.
• Cornea: Esiae nye ŋkua ƒe akpa si me kɔ eye wòle abe ahuhɔ̃e ene le ŋgɔgbe, abe fesre ene.
• Ŋkuʋuʋu: Esia nye lãkusi tsɛ aɖe si kpɔa ŋkua ta.

Ʋuka yeyewo ƒe wɔwɔme le ʋukawo ƒe ƒuƒoƒo me `(Choroidal Neovascularization - CNV)`

Azɔ mina míalé ŋku ɖe `(Choroid)` sia ŋu, si fia be ʋuka yeyewo ƒe wɔwɔme le ʋukawo ƒe ƒuƒoƒoa me. Woyɔa esia be `(Choroidal Neovascularization - CNV)`.

Esia dzena zi geɖe le amesiwo ŋu ŋku ƒe dɔmawɔmawɔ nyuie (AMD) le le ƒexɔxɔ ta me. Ðɔktawo xɔe se be nusi gbɔ wòtsoe nye atike aɖe si woyɔna be Vascular Endothelial Growth Factor (VEGF), si ame si ŋu AMD le ƒe ŋkumeʋuʋu wɔna la ƒe agbɔsɔsɔ si dzi ɖe edzi.

Ʋuka yeye siawo mesɔ o. Wogbɔdzɔ ŋutɔ, abe pɔmpi gbagbã ene.Esia ate ŋu ana tsi, eye ɣeaɖewoɣi ʋu gɔ̃ hã, nado ɖe ŋkume ƒe ŋkume. Bu eŋu abe ʋuƒo sue aɖe si me tsi yɔ fũ ene, eye ʋuʋudedi ate ŋu ado ɖe ŋku ƒe ŋkume.

Nusiwo gbɔ `(CNV)` tsona siawo ateŋu ana ʋuka yeyewo hã nadzɔ le ŋku ƒe titina (Macular Neovascularization - MNV). Ke hã, ɣeaɖewoɣi la, `(MNV)` ate ŋu adzɔ susu aɖeke manɔmee. Le nɔnɔme siawo tɔgbe me la, wogayɔnɛ be `(Idiopathic)`, si gɔmee nye "nusi womenya nusi gbɔ wòtso o".

Ŋku ƒe Ʋuka Yeyewo ƒe Dɔléle

Eyome, mina míaƒo nu tso ʋuka yeyewo ƒe wɔwɔme le ŋkume ƒe ŋkume ŋu. Ðo ŋku edzi be ŋkume ƒe akpa si me kɔ lae nye ŋkua ƒe akpa si me kɔ. Zi geɖe la, ʋuka aɖeke mele eŋu kura o. Esia tae wòdze ƒã alea ɖo. Eyata ne ʋuka yeyewo va le eme la, woate ŋu agblẽ nu ma me kɔ nyuie, eye wòadze abe afu ene. Esia ate ŋu ana nukpɔkpɔ natsi.

``Corneal Neovascularization`` sia do ƒome kple ŋku ƒe nɔnɔme vovovowo.

Retina ƒe Ʋuka Yeyewo ƒe Dɔléle

Retinal neovascularization nye ʋuka yeye siwo mesɔ o ƒe wɔwɔme le ŋkua ƒe ŋkume. Ðo ŋku edzi be ŋkume ƒe ŋkume ƒe lãmenugbagbevi siwo dea dzesi kekeli la le. Dɔléle kple abi vovovowo ate ŋu ahe nɔnɔme sia vɛ. Ʋuka yeye siawo gbɔdzɔ eye woate ŋu ado ʋu eye tsi nado le wo me.

Neovascularization of the Iris ƒe ʋuka yeyewo

Iris Neovascularization nye ʋuka yeye siwo mesɔ o ƒe dzɔdzɔ le iris me – ŋku ƒe akpa si naa amadede ŋkua. Wogayɔnɛ be Rubeosis Iridis. Edo ƒome kple ŋkudɔ sesẽ aɖe si woyɔna be Neovascular Glaucoma. Glaucoma nye dɔléle si gblẽa nu le ŋku ƒe lãmeka ŋu eye wònye afɔku gã aɖe na nukpɔkpɔ.

Nukae nye nɔnɔme sia ƒe dzesiwo?

Azɔ mina míakpɔ dzesi siwo míesena le mía ɖokui me eye míakpɔ ne ʋuka yeyewo va le ŋkua me ɖa. Dzesi siawo ate ŋu ato vovo le afisi ʋuka yeyeawo dzɔ le nu.

Ne ʋuka yeyewo do le choroid kple macula me la:

• Nu siwo nèkpɔ la ate ŋu adze abe ɖe wotro eye wotro ene , abe ŋkuléle ɖe tsi me alo to ahuhɔ̃e si tro me ene.
• Ne èkpɔ ŋgɔ tẽ la, àte ŋu akpɔ teƒe ƒuƒlu alo teƒe yibɔ aɖe le wò ŋku ƒe titina .

Ne ʋuka yeyewo do le ŋkume ƒe ŋkume (Corneal Vascularization):

Ðewohĩ dzesi aɖeke manɔ ŋuwò kura o. Gake ne èwɔe nenema la, àte ŋu ato nu siwo gbɔna me:

• Ŋku ƒe vevesese.
• Ŋkuwo ƒe biã.
• Ŋku siwo me tsi le.
• Kekeli ƒe seselelãme (Photophobia) - Esia fia be nuwo abe ɣe ƒe keklẽ kple akaɖi siwo klẽna ene kpɔkpɔ sesẽ.
• Ne èdo ŋkumeɖonu la, ɖewohĩ màte ŋu adoe wu gaƒoƒo ʋɛ aɖewo o.

Nukatae esia le dzɔdzɔm? Nukawoe nye susu siwo tae?

Enyo, azɔ mina míalé ŋku ɖe nusita ʋuka yeyewo dzɔna le ŋkua me alea ŋu, kple nusiwo gbɔ wòtsona. Susu siwo tae wowɔa nu siawo ɖo la to vovo vie le teƒe ɖesiaɖe.

Nusiwo nana ʋuka yeyewo dzɔna le choroid kple macula me:

• Macular degeneration: Esia koŋ gbɔe wòtsona.
• Nukpɔkpɔ kpuie si gbɔ eme.
• Ocular histoplasmosis nye fungi ƒe dɔléle si le ŋkua ŋu.
• Ŋku ƒe abixɔxɔ.
• Angioid streaks: Esiawo le abe gbagbãƒe siwo dzɔna le ŋkume ƒe ƒuƒoƒo ɖeka me ene.
• Uveitis: Esia nye ŋkudɔ siwo ate ŋu ana ŋkua naxɔ abi, abiã, eye ŋku nase veve.

Nusiwo nana ʋuka yeyewo dzɔna le ŋkume ƒe ŋkume:

• Dɔléle siwo wodzina: Esiawo nye dɔléle siwo nɔa ame ŋu le vidzidzi me.
• Ŋku ƒe nuveviwɔame: Le kpɔɖeŋu me, atikewo ƒe dzobibi.
• Keratitis si xɔa ame me.
• Nusiwo ŋu nulɔdɔ le.
• Dɔlélenutsiŋutete kple dɔdzẽ ƒe dɔlélewo.
• Lãmetsiŋusẽ ƒe ŋkumeɖonu zazã ɣeyiɣi didi ate ŋu ana lãmenugbagbeviwo naxɔ oxygen o (Hypoxia).
• Gbegbe na ŋkume ƒe ŋkumeʋuʋu si ŋutilãa do.

Nusiwo nana ʋuka yeyewo dzɔna le ŋku ƒe ŋkume:

• Ŋku ƒe dɔléle.
• Ŋku ƒe dɔléle: Esia lɔ nɔnɔmewo abe ŋkudɔ si do ƒome kple suklidɔ, ŋkume ƒe dɔléle si nye sickle cell, kple ŋkume ƒe dɔléle si do ŋgɔ na ɣeyiɣi si woɖo ɖi ene ɖe eme.
• Ʋu ƒe sisi le ʋuka vevi siwo le wò kɔ me (carotid arteries) me dzi ɖe kpɔtɔ.
• Retinal vein occlusion: Esia nye ʋuka aɖe si le retina me ƒe xexe.

Nusiwo hea ʋuka yeyewo vɛ le ŋkume ƒe ŋkume:

• Suklidɔ si do ƒome kple ŋku ƒe dɔléle.
• Titina ŋku ƒe ʋuka ƒe ʋuʋu.
• Ocular ischemic syndrome: Nɔnɔme si tsoa ʋu ƒe sisi yi ŋkua me dzi ɖeɖe kpɔtɔ gbɔ.
• Retinal detachment: Esiae nye ne retina la ɖe eɖokui ɖa tso lãmeka siwo kpena ɖe eŋu gbɔ.
• Uveitis ƒe dɔléle.

Aleke nèwɔ de dzesi esia? Nukawoe nye dodokpɔawo?

Enyo, ne dzesi siawo tɔgbe le ŋuwò la, aleke tututu ɖɔkta awɔ anya dɔlélea? Dodokpɔ geɖe li na ema.

• Dilated slit akaɖi ŋku dodokpɔ:Le esia me la, wotsɔa ŋkumetsiwo dea ŋkua ŋu, wodzia ŋkua ƒe ŋkume , eye wotsɔa dɔwɔnu tɔxɛ aɖe abe nusuekpɔmɔ̃ ene doa ŋkua ƒe akpa si le eme la kpɔna nyuie.
• Optical Coherence Tomography (OCT): Esia le abe ŋkua ƒe akpa si le eme ƒe fotoɖeɖe ene. Ate ŋu aɖe ƒuƒoƒo siwo le ŋkua me ƒe nɔnɔmetata siwo me kɔ siwo wotso ɖe wo nɔewo ŋu. Ate ŋu adi nuwo abe ʋuka yeyewo kple tsi siwo le dodom ene.
• Fluorescein angiography alo Indocyanine green angiography: Esia bia be nàdo amadede tɔxɛ aɖe ɖe ʋuka aɖe si le wò alɔnu me eye nàɖe ʋuka siwo le wò ŋku me ƒe foto. Esia ate ŋu aɖe nuwo abe ʋukawo ƒe xexe kple tsi si le dodom le ʋukawo me ene afia kɔte.

Nukawoe nye atikewɔmɔnuawo?

Dɔléle sia ƒe atikewɔwɔ toa vovo le nusi gbɔ wòtso kple ŋkua ƒe akpa si wògblẽ nu le nu. Zi geɖe la, atikewɔmɔnu siawo dometɔ aɖewoe nye atikewo kple/alo ʋukawo ɖeɖeɖa, si gblẽa ʋuka yeye siwo mesɔ o.

Atike ƒomeviwo:

Esiawo dometɔ aɖewo nye atike siwo wodona ɖe ŋkume si wodona ɖe ŋkua me tẽ. Esiawo wɔa dɔ koŋ to atike aɖe si woyɔna be VEGF dzi ɖuɖu kple ʋuka yeyewo ƒe wɔwɔme dzi ɖeɖe kpɔtɔ me.

• `Bevacizumab (Avastin®)` (Wozãa esia `(off-label)`, si fia be menye dɔléle si dzi woda asi ɖo nae o, ke boŋ le esi wonya be eɖea vi ta)
• `Brolucizumab (Beovu®) ƒe atike si wotsɔna ƒoa ƒui`
• `Aflibercept (Eylea®)`
• `Ranibizumab (Lucentis®) ƒe atike si wotsɔna ƒoa ƒui`
• Domenyiŋusẽfianu ƒe atikewɔwɔ: Esia nye atikewɔwɔmɔnu yeye aɖe si wogale numekuku wɔm le.
• MMP mɔxenuwo: Le kpɔɖeŋu me, atikekui aɖe si woyɔna be Doxycycline , si wonana be wòana ʋuka yeyewo natsi le ŋkume ƒe ŋkume.

Mɔnu siwo gblẽa lãmeka siwo mesɔ o:

• Laser ablation therapy: Esia zãa laser beams tsɔ "tɔ dzo" eye wogblẽa ʋuka yeyeawo dome.
• Photodynamic therapy (PDT): Esia bia be woado atike si sea kekeli ɖe ŋkua me, emegbe woaklẽ kekeli tɔxɛ aɖe ɖe ŋkua me be wòatia ʋuka siwo mesɔ o la.
• Dzoxɔxɔ: Mɔnu sia zãa dzoxɔxɔ tsɔ daa ʋuka siwo mesɔ o.

Ðo ŋku edzi hã be: Dɔdamɔnu siawo ate ŋu agblẽ nu le ame ŋu. Le kpɔɖeŋu me, steroid kple atike siwo tsia VEGF nu ate ŋu agblẽ nu le ame ƒe ŋutilã bliboa ŋu. Azɔ hã, ne wogblẽ ʋukawo dome la, lãmeka siwo le lãmesẽ me ate ŋu agblẽ ɣeaɖewoɣi. Eyata ele vevie be nàdzro atikewɔwɔ ɖesiaɖe ƒe viɖe kple kuxiwo me kple wò ɖɔkta eye nàtia esi anyo na wò.

Nukae míate ŋu awɔ atsɔ akpɔ mía ɖokui ta tso nɔnɔme sia me?

Togbɔ be womate ŋu axe mɔ ɖe nɔnɔme sia nu keŋkeŋ o hã la, nanewo li míate ŋu awɔ atsɔ alé be na míaƒe ŋkuwo ahaɖe afɔkua dzi akpɔtɔ:

• Hafi woawɔ ŋkume kple ŋkumeKlɔ asi nyuie kple adzalẽ.
• Ne èdo ŋkumeɖonu la, wɔ ɖe mɔfiame nyuitɔ siwo ku ɖe wo zazã kple wo ŋu kɔklɔ ŋu dzi. Mègado wo wòadidi wu ɣeyiɣi si woɖo ɖi o. Ðe wo ɖa ne èle alɔ̃ dɔm.
• Bia wò ɖɔkta tso nuɖuɖu kple kpeɖeŋutɔ siwo ate ŋu akpe ɖe ŋuwò be wò ŋkuwo nanɔ lãmesẽ me ŋu. Le amesiwo ŋu AMD le gome la, kpeɖeŋutɔ ƒomevi aɖe li si woyɔna be AREDS 2 si ate ŋu akpe ɖe ame ŋu woatɔ te dɔlélea ƒe ŋgɔyiyi alo aɖu edzi le eƒe gɔmedzedze.
• Wɔ ɖe agbenɔnɔ si me lãmesẽ le dzi. Esia fia be nàɖu nuɖuɖu si da sɔ, ade kame edziedzi , eye nàtsri atamanono. Ne dɔléle aɖewo le ŋuwò, abe suklidɔ alo ʋusɔgbɔdɔ ene la, ɖu wo dzi nyuie.

Nukae woate ŋu akpɔ mɔ na le nɔnɔme sia me?

Ne womeda ʋuka yeye sia ƒe wɔwɔme o la, wò ŋkua dzi aɖe akpɔtɔ vivivi eye wòabu mlɔeba. Ema akpɔ ŋusẽ gã aɖe ɖe wò agbe dzi, alo?

Nu geɖe li siwo kpɔa ŋusẽ ɖe nenye be atikewɔwɔa akpɔ dzidzedze. Esiawo dometɔ aɖewoe nye afisi ʋua le, alesi wòsẽe, ƒe si nèxɔ, kple ne lãmesẽkuxi bubuwo le ŋuwò. Zi alesi wokpɔ dɔlélea le eŋu kaba hedae la, zi nenemae emetsonua nyonae.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne wò ŋku megakpɔa nu nyuie o, wò ŋkuwo le veve sem vevie, alo wò ŋkuwo le bibim si wɔe be wòsesẽna be nàkpɔ kekeli la, yi ɖɔkta gbɔ enumake. Azɔ hã, ne ède dzesi tɔtrɔ aɖewo le wò ŋkumekpɔkpɔ me (e.g., ŋkumekpɔkpɔ si me kɔ o, teƒe yibɔwo), alo dzesi bubu ɖesiaɖe si nèsusu be ate ŋu anye kuxi la, yi ŋkudɔdala gbɔ enumake.

Ele vevie hã be nàdo ŋku kpɔ edziedzi abe alesi wò ŋkudɔdala kafui ene. Ne èle afɔku me na ŋku ƒe dɔléle aɖewo (e.g., suklidɔ, AMD ƒe ƒome ŋutinya) la, ɖewohĩ ahiã be nàyi enuenu.

Ðe ``Neovascularization'' kple ``Angiogenesis'' nye nu vovovo evea?

Esia nye nya si me goglo vie, gake ne míagblɔe kpuie la, `(Angiogenesis)` nye ʋuka yeyewo ƒe alɔdze tso ʋuka siwo li xoxo me ƒe ɖoɖo. `(Vasculogenesis)` nye ʋuka yeyewo ƒe dɔwɔwɔ si dzea egɔme tso lãmenugbagbeviwo dzi (abe ɖe wòdze egɔme tso gɔmedzedzea me ene). Woateŋu azã `(Neovascularization)` atsɔ awɔ ʋuka yeyewo le mɔ eveawo siaa nu. Eyata `(Neovascularization)` nye nya si keke vie, eye ateŋu alɔ ʋuka yeyewo ƒe wɔwɔme ƒomevi siawo katã ɖe eme.

Nu vevitɔ kekeake siwo dzi wòle be míaɖo ŋkui tso ŋutinya sia mee nye

Eyata, míeƒo nu geɖe tso nɔnɔme sia si woyɔna be ``Neovascularization of the Eye'', afisi ʋuka yeyewo dzɔna le ŋkua me. Togbɔ be esia adze nu dziŋɔ vie hã la, ne wokpɔe dze sii hedae le ɣeyiɣi nyuitɔ dzi la, mɔnukpɔkpɔ gã aɖe li be woate ŋu akpɔ nɔnɔmea gbɔ eye woakpɔ nukpɔkpɔ ta.

• Ne èkpɔ tɔtrɔ kpata le nukpɔkpɔ me, wò biã, nèse veve, alo wòsesẽ be nàkpɔ nu le kekeli si klẽna me la, mègahe ɖe megbe o. Yi ŋkudɔdala gbɔ enumake.
• Ne nɔnɔme aɖewo abe suklidɔ, ŋku ƒe ʋuʋu fũu akpa, alo AMD le ƒomea me ene le ŋuwò la, na woado wò ŋkuwo kpɔ edziedzi abe alesi wò ɖɔkta gblɔe ene.
• Zã atike si wò ɖɔkta ŋlɔ na wò pɛpɛpɛ, wɔ ɖe eƒe mɔfiamewo dzi, eye mègadzudzɔ atikewɔwɔ le titina o.
• Ƒo asa na atamanono keŋkeŋ. Sigaretnono gblẽa nu le ŋku ƒe lãmesẽ ŋu ŋutɔ, vevietɔ le nɔnɔmewo abe AMD kple suklidɔ ƒe ŋkudɔ ene gome.
• Menye ɖeko nuɖuɖu nyui kple kamedede edziedzi nyo na wò ŋkuwo ko o, ke enyo na wò ŋutilã bliboa hã. De amagbe damawo, atikutsetsewo, kple tɔmelã siwo me omega-3 sɔ gbɔ ɖo wò nuɖuɖu me.

Ðo ŋku edzi be wò ŋkuwo xɔ asi ŋutɔ. Woawoe nye nunɔamesi xɔasitɔ kekeake si le mía si be míakpɔ xexeame. Eya ta, wò agbanɔamedzie wònye be nàlé be na wo nyuie. Ne ènya do ŋgɔ eye nèɖe afɔ siwo hiã la, àte ŋu aƒo asa na kuxi geɖe.

` Neovascularization of the Eye, Ŋkudɔlélewo, Nukpɔkpɔ, Retina, Ŋkudɔléle, Ŋkudɔdada