Ðe ta ɖua wò hã ɣeaɖewoɣi le susu manɔmeea? Alo ɖe nèsena le ɖokuiwò me be yeƒe ŋkuwo gbɔdzɔ vie, eye mète ŋu kpɔa nuwo tso axawo dzi nyuie oa? Alo, ɖe tɔtrɔ aɖewo siwo va le wò ŋutilã ƒe lãmetsiŋusẽwo me hena vɛ na wòa? Ðewohĩ nusi gbɔ nusiawo tsoe nye dɔdzẽ sue aɖe si dona le wò lãkusi me. Egbea, míaƒo nu tso nɔnɔme sia si woyɔna be Pituitary Adenoma ŋu tsitotsito. Mègatsi dzi o, menye kansae nye esia o.

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Nukae nye pituitary adenoma?

Kpuie ko la, pituitary adenoma nye dɔdzẽ si menye kansa o (si me dɔlékui aɖeke mele o) si dona le wò pituitary gland me. Mekakana ɖe ŋutilã ƒe akpa bubuwo abe kansa ene o. Emae nye nu vevitɔ kekeake. Gake ne adenoma sia le tsitsim la, ate ŋu azi nuwo abe lãmekawo kple ʋuka siwo ƒo xlãe ene dzi. Ɣemaɣie dzesiawo dzea egɔme dzena.

Eyata nukae nye pituitary gland sia?

Bu eŋu kpɔ, le míaƒe ŋɔti megbe, si do ƒome kple ahɔhɔ̃a ƒe gɔme, Hypothalamus, lãkusi sue aɖe si lolo abe pea ene li. Emae nye nusi woyɔna be pituitary gland. Togbɔ be ele sue hã la, ewɔa dɔ vevi aɖe ŋutɔ le míaƒe ŋutilã me. Akpa vevi eve le lãkusi sia ŋu:

Anterior Lobe ƒe akpa si le ŋgɔgbe
Megbe ƒe Akpa

Akpa siawo evea siaa wɔa lãmetsiŋusẽ ƒomevi vovovowo heɖea wo ɖe go yia ʋukawo me. Lãmetsiŋusẽwo le abe atikewo ƒe dɔla siwo kpɔa míaƒe ŋutilã ƒe dɔwɔna vovovowo dzi hewɔa ɖoɖo ɖe wo ŋu ene. Wozɔa mɔ to ʋukawo me heɖoa gbedasi siwo hiã la ɖe míaƒe ŋutinuwo, lãmekawo, kple lãmenugbagbevi bubuwo. Lãmetsi vevi siwo pituitary gland wɔna dometɔ aɖewoe nye esi:

Lãmetsiŋusẽ si naa adrenocorticotropic (ACTH alo Corticotropin) .
Lãmetsiŋusẽ si tsia tsinyegoe me (ADH alo Vasopressin) .
Lãmetsiŋusẽ si doa ŋusẽ lãkusi ( FSH ) .
Tsitsi ƒe lãmetsi (GH) .
Lãmetsiŋusẽ si naa luteinizing (LH) .
Oxytocin ( Oxytocin ) ƒe dɔ.
Prolactin si wotsɔ wɔa dɔe
Lãmetsiŋusẽ si doa ŋusẽ lãkusi (TSH) .

Menye esia ɖeɖeko o, pituitary gland hã "dea dzesi" endocrine gland bubu siwo le míaƒe ŋutilã me be woawɔ lãmetsiwo. Eyata àte ŋu ase egɔme be ne kuxi aɖe le lãkusi sia ŋu abe adenoma ene la, ate ŋu agblẽ nu le lãmetsiŋusẽ ɖeka alo lãmetsi geɖe ƒe dɔwɔwɔ ŋu.

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Aleke wodea vovototo adenoma ƒomevi siawo me?

Ðɔktawo ma pituitary adenomas ɖe hatsotso vevi eve me: 1. Wonɔ te ɖe edzi be wowɔa lãmetsiŋusẽwo alo womewɔa wo o:

Adenoma ƒe Dɔwɔwɔ/Eɖeɖe ɖe go:Tsɔ kpe ɖe eŋu la, adenoma siawo ƒomevi wɔa pituitary hormone ɖeka alo esi wu nenema . Eyata dzesi kple nɔnɔme vovovowo ate ŋu ado mo ɖa le lãmetsiŋusẽ si wowɔ wògbɔ eme nu.
Adenoma siwo mewɔa dɔ o/siwo meɖea nu le ame ŋu o: Adenoma siawo mewɔa lãmetsiŋusẽ o. Gake ne wololo la, woate ŋu ahe dzesiwo vɛ ne wozi ahɔhɔ̃a ƒe akpa siwo te ɖe wo ŋu alo lãmekawo dzi . Esiae nye adenoma ƒomevi si ɖɔktawo doa goe zi geɖe.

2. Le eƒe lolome nu:

Microadenomas: Esiawo nye dɔdzẽ siwo le sue wu milimeta 10 (si fia be sentimeta 1).
Macroadenomas: Esiawo nye dɔdzẽ siwo lolo wu milimeta 10. Macroadenomas bɔ abe microadenomas ene zi gbɔ zi eve. Woate ŋu ana lãmetsiŋusẽ ɖeka alo esi wu nenema (nɔnɔme si woyɔna be hypopituitarism) naɖiɖi hã.

Ðe wobua esia be enye ahɔhɔ̃ me dɔdzẽa?

Le nyateƒe me la, lãkusi nye lãmenugbagbeviwo ƒe wɔwɔme si le lãmenugbagbeviwo ƒe dɔwɔwɔ me, eye le mɔ̃ɖaŋununya gome la, menye ahɔhɔ̃a ƒe akpa aɖekee wònye o. Ebla ɖe ahɔhɔ̃a ƒe gɔme. Gake ɖɔktawo bua pituitary adenomas be enye ahɔhɔ̃ me dɔdzẽ ƒomevi aɖe . Pituitary adenomas nye ahɔhɔ̃meka gbãtɔwo ƒe 10% ko.

Amekae xɔa nusiawo zi geɖe wu? Aleke gbegbe wòbɔe?

Pituitary adenomas ate ŋu adze le ƒe ɖesiaɖe me. Gake wobɔ ɖe amesiwo xɔ ƒe 30 kple 40 me wu . Nyɔnuwo hã ate ŋu axɔ wo vie wu ŋutsuwo. Wobɔ ale gbegbe be woxɔa dɔdzẽ siwo katã tsina le taɖua me ƒe 10% va ɖo 15%. Akɔntabubuwo ɖee fia be dɔléle sia le ame siwo ade 77 le ame 100,000 dome. Gake numekulawo xɔe se be ame geɖe wu, ɖewohĩ wo dometɔ siwo ade 20%, axɔ ɖeka le woƒe agbe me ɣeaɖeɣi. Zi geɖe, vevietɔ amesiwo ŋu microadenomas (microadenomas) le, mekpɔa dzesi aɖeke o, eyata womedea dzesii o.

Nukae nye pituitary adenoma ƒe dzesiwo?

Pituitary adenoma ƒe dzesiwo ate ŋu ato vovo ŋutɔ tso ame ɖeka gbɔ yi bubu gbɔ. Nu geɖe dzie wònɔ te ɖo koŋ:

Ne adenoma la tsina le lolome me eye wògblẽa nu le pituitary gland ŋutɔ ŋu, alo nenye be ehea mass effect'' vɛ ɖe xɔtunu siwo ƒo xlãe dzi.
Ðe wònye adenoma si ɖea lãmetsiŋusẽ (dɔwɔwɔ) ɖaa? Ne nenemae la, dzesiawo anɔ te ɖe lãmetsi si ƒomevi wòwɔna dzi.

Mass Effect dzesi siwo tso Macroadenomas (dɔdzẽ gãwo) gbɔ .

Adenoma gãwo (Macroadenomas) hea dzesiwo vɛ vevietɔ le nyaƒoɖeamenu si le lãkusi siwo ƒo xlãe ŋu ta.

Bu eŋu kpɔ ko, ne ètsɔ nu gã aɖe da ɖe xɔ sue aɖe me la, ɖeko wòle abe ɖe teƒe mesɔ gbɔ na nu bubuwo o eye amewo yɔe fũ ene.

Ŋku ƒe nukpɔkpɔ ƒe kuxiwo:

Ame siwo ŋu pituitary adenoma gã aɖe le la dometɔ siwo ade 40% va ɖo 60%Nukpɔkpɔ ƒe bu (nukpɔkpɔ si me mekɔ o, nukpɔkpɔ zi eve) dzɔna. Esia dzɔna elabena adenoma la tea ŋku ƒe lãkusi si doa ka kple ŋkuwo kple ahɔhɔ̃a. Esia ate ŋu ana be ame ƒe ŋkuwo nagate ŋu akpɔ nu le gota gome o, vevietɔ le axadzi. Ele abe sɔ si megate ŋu kpɔa nu le axa eveawo dzi o ene.

Taɖuame : .

Ame geɖe siwo ŋu pituitary adenomas le toa nyatoƒoe le taɖuame enuenu ŋu. Esia ate ŋu atso dɔdzẽa ƒe tete ɖe lãkusi siwo ƒo xlãe dzi gbɔ. Gake esi wònye be zi geɖe la, nu geɖe gbɔe taɖuame tsona ta la, nu bubuwo hã ate ŋu ahe taɖuame vɛ.

Lãmetsiŋusẽ ƒe Dɔmawɔmawɔ:

Adenomas gãwo (Macroadenomas) ateŋu agblẽ nu le pituitary gland ƒe lãkusi ŋu eye wòaɖe pituitary hormone ɖeka alo esi wu nenema ƒe wɔwɔ dzi akpɔtɔ. Woyɔa nɔnɔme sia be Hypopituitarism. Dzesi siwo dzena ne woɖe lãmetsi ɖesiaɖe dzi kpɔtɔ hã toa vovo.

Ne LH kple FSH lãmetsiwo dzi ɖe kpɔtɔ (Hypogonadism): Oestrogen ƒe agbɔsɔsɔ le nyɔnuwo me kple Testosterone ƒe agbɔsɔsɔ le ŋutsuwo me dzi ɖena kpɔtɔna. Esia ateŋu ahe dzesiwo abe fifia fũu akpa , vidzidɔ ƒe ƒuƒu le nyɔnuwo me, Erectile Dysfunction le ŋutsuwo me, mo kple ŋutilã ƒe fu ƒe tsitsi dzi ɖeɖe kpɔtɔ, seselelãme ƒe tɔtrɔ le ŋutsu eveawo siaa me, gbɔdɔdɔ ƒe dzodzro dzi ɖeɖe kpɔtɔ, kple ɖeɖiteameŋu si gbɔ eme.
Ne TSH lãmetsiŋusẽ ƒe agbɔsɔsɔ dzi ɖe kpɔtɔ (Hypothyroidism): Lãmetsi siwo lãkusia wɔna ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna. Esia ate ŋu ahe dzesiwo abe ɖeɖiteameŋu, dɔmeɖui, dzi ƒe tsotso blewu, ŋutigbalẽ ƒe ƒuƒu, abɔ kple afɔwo ƒe vuvu, kple lãmekawo ƒe dɔwɔwɔ ƒe gbegblẽ ene vɛ.
Ne ACTH lãmetsiŋusẽ le sue (Adrenal Insufficiency): Ŋutilã ƒe lãmetsi si nye Cortisol wɔwɔ dzi ɖena kpɔtɔna. Esia ate ŋu ahe dzesiwo abe ʋu ƒe sisi, ʋuʋudedi, ʋuʋudedi, ƒodo ƒe veve, kple nuɖuɖu ƒe dzodzro ene vɛ.
GH (Growth Hormone Deficiency): Dzesiawo toa vovo le ƒe si woxɔ nu. Ðeɖi ate ame tsitsiwo ŋu eye woƒe lãmekawo nabu.

Adenomas siwo le dɔ wɔm ƒe dzesiwo

Tsɔ kpe ɖe lãmetsiŋusẽ ɖeka alo esi wu nenema ƒe dodo ŋu la, adenoma si wɔa dɔ ate ŋu ahe dzesi kple nɔnɔme vovovo siwo do ƒome kple lãmetsi ɖesiaɖe vɛ.

Prolactinomas (si woyɔna hã be Lactotroph Adenomas):

Adenoma siawo wɔa lãmetsi si nye prolactin la fũ akpa. Woyɔa nɔnɔme sia be hyperprolactinemia. Pituitary tumors siwo ade 4 le 10 ɖesiaɖe me koe nye esia ƒomevi. Esiae nye pituitary adenoma ƒomevi si bɔ wu.Ne prolactin ƒe agbɔsɔsɔ dzi ɖe edzi la, ate ŋu agblẽ vidzidzi ƒe dɔwɔwɔ nyuie le nyɔnuwo kple ŋutsuwo siaa me.

Vidzidzi nye nɔnɔme si me wòsesẽna na ŋutsuwo kple nyɔnuwo siaa be woafɔ fu.
Notsi si dona tso no me ne mefɔ fu o gɔ̃ hã (Galactorrhea).

Somatotroph Adenomas: Nusiwo wotsɔna ƒoa ƒui:

Adenoma siawo wɔa tsitsi ƒe lãmetsi (Growth Hormone alo Somatotropin) si gbɔ eme . Pituitary tumors siwo ade 2 le 10 ɖesiaɖe me nye esia ƒomevi. Dzesi siwo esia hena vɛ la toa vovo le ƒexɔxɔ nu.

Ame tsitsiwo: Nɔnɔme aɖe si mebɔ o gake wònye nu sesẽ si woyɔna be Acromegaly la dzɔna. Le esia me la, ŋutilãa ƒe ƒuwo kple lãkusiwo tsina le mɔ si mesɔ o nu. Le ɣeyiɣi aɖe megbe la, asiwo, afɔwo, kple ta va lolona, eye mo ƒe nɔnɔme trɔna. Ekpɔa ŋusẽ ɖe sukli si le ʋu me dzi ɖuɖu hã dzi, eye dzitodzito ƒe lãmeka hã ate ŋu alolo.
Ðeviwo kple sɔhɛ tsitsiwo: Nɔnɔme aɖe si woyɔna be gigantism dzɔna. Wotsina le mɔ si mesɔ o nu le tsitsi ƒe lãmetsi si sɔ gbɔ ta.

Corticotroph Adenomas ƒe dɔlélewo:

Adenoma siawo wɔa ACTH (adrenocorticotropic hormone) fũ akpa . Pituitary tumors siwo ade 1 le 10 ɖesiaɖe me nye esia ƒomevi. ACTH lãmetsiŋusẽa ʋãa adrenal glands be woawɔ steroid lãmetsi geɖe abe cortisol ene. Esia hea Cushing ƒe Dɔléle (cortisol si sɔ gbɔ) vɛ.

Ʋusɔgbɔdɔ.
Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ.
Nuveviwɔame bɔbɔe.
Aɖabɛ ƒe fli siwo keke (si wu sentimeta 1) (Stretch Marks) dzena le ƒodoa dzi.
Ƒumeŋuɖui ƒe dɔléle.
Nutete ƒe gbagbãƒewo.
Suklidɔ Ƒomevi 2 lia.

Thyrotroph Adenomas: Ʋumenugbagbeviɣidɔlékuiwo:

Adenoma siawo naa TSH (lãmetsiŋusẽ si doa ŋusẽ ʋumenugbagbeviɣidɔ) si gbɔ eme . Esiawo mebɔ kura o. TSH ʋãa lãkusia be wòawɔ lãkusi me lãmetsi geɖe. Esia hea Hyperthyroidism (thyroid nɔnɔme si wɔa dɔ fũu akpa), si naa ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ kabakaba.

Dzi ƒe tsotso ƒe dzidziɖedzi.
Lolo dzi ɖeɖe kpɔtɔ susu aɖeke manɔmee.
Aɖuɖɔ si me mekɔ o enuenu.
Fifia ƒe ʋuʋu.
Asi ƒe ʋuʋu.
Dzitsitsi.

Vevietɔ: Nu bubu geɖewo hã li siwo hea ʋumenugbagbeviɣidɔ vɛ. Pituitary adenoma nye nusi mebɔ kura o.

Gonadotroph ƒe Adenomawo:

Adenoma siawo wɔa gonadotropins (i.e., lãmetsi siwo nye LH kple FSH) ƒe agbɔsɔsɔ si gbɔ eme. Esia hã mebɔ kura o.

Esia ate ŋu ana nyɔnuwo nakpɔ dzinukpɔkpɔ si mesɔ o kple nɔnɔmewo abe Ovarian Hyperstimulation Syndrome (OHSS) ene.
Ŋutsuwo ate ŋu akpɔ dzesiwo abe vidzidɔ ƒe lolome, gbe ƒe gogloƒe, taɖa ƒe gege (to megbe), kple mo ƒe fu ƒe tsitsi kabakaba.
Ðeviwo hã ate ŋu akpɔ sɔhɛmenɔɣi kaba.

Nukawoe hea pituitary adenoma vɛ?

Dzɔdzɔmeŋutinunyalawo menya nusi tututu hea adenoma siawo vɛ haɖe o. Gake wosusu be adenoma aɖewo do ƒome kple tɔtrɔ siwo dzɔna le vome (nutations) le domenyiŋusẽfianu (DNA) siwo le míaƒe lãmenugbagbeviwo me. Domenyiŋusẽfianu ƒe tɔtrɔ siawo nana lãmenugbagbevi siwo le lãkusi me tsina kabakaba eye wowɔa nu gbogbo aɖe. Domenyiŋusẽfianu ƒe tɔtrɔ siawo ate ŋu anye domenyinyi tso dzilawo gbɔ vaseɖe ɖeviwo gbɔ ɣeaɖewoɣi (domenyiŋusẽ me tɔ), alo woate ŋu adzɔ le vome keŋkeŋ. Tsɔ kpe ɖe eŋu la, woate ŋu atsɔ pituitary adenomas hã asɔ kple domenyiŋusẽfianu ƒe nɔnɔme aɖewo siwo mebɔ o . Kpɔɖeŋu aɖewoe nye:

Multiple Endocrine Neoplasia ƒomevi 1 (MEN1)''.
Multiple Endocrine Neoplasia ƒomevi 4 (MEN4)''.
Carney ƒe ƒuƒoƒo
X-LAG ƒe dɔléle
Succinate dehydrogenase-si do ƒome kple ƒome ƒe pituitary adenoma''.
Neurofibromatosis ƒomevi 1
Von Hippel–Lindau ƒe dɔléle''.

Ame si ŋu domenyiŋusẽfianu ƒe nɔnɔme sia le la le afɔku gã aɖe me be wòaxɔ pituitary adenoma. Gake ele vevie be míaɖo ŋku edzi be ame siwo si domenyiŋusẽfianu ƒe nɔnɔme ma tɔgbe aɖeke mele o hã ate ŋu axɔ adenoma siawo.

Aleke ɖɔktawo wɔa dea dzesi dɔléle siae?

Alesi wokpɔa pituitary adenoma la toa vovo le adenoma ƒomevi si le ŋuwò kple nenye be eyae le dzesiwo hem vɛ nu. Zi geɖe la, wokpɔa lãmetsiŋusẽ ƒe masɔmasɔ (e.g. Cushing's Syndrome, Acromegaly) le amesi ŋu lãmetsiŋusẽ ƒe adenoma (Functioning Adenoma) le gbã le dzesiawo nu. Ema ko hafi wova kea ɖe adenoma la ŋu ne woku nusi gbɔ wòtso me. Esia le alea elabena nɔnɔme geɖe siwo lãmetsiŋusẽ ƒe agbɔsɔsɔ fũ hena vɛ ate ŋu atso nu bubuwo gbɔ tsɔ kpe ɖe pituitary adenomas ŋu. Woate ŋu agblɔ nya ma ke le pituitary hormone ƒe anyimanɔmanɔ (Hypopituitarism) hã ŋu. Ɣeaɖewoɣi la, wokpɔa pituitary adenoma be enye Incidental Finding le ta scan (Imaging Test) me hena nɔnɔme bubu. Zi geɖe la, adenoma akpa gãtɔ siwo wokpɔna alea la nɔa sue eye womewɔa dɔ o.

Dodokpɔ kawoe wowɔna na esia?

Ne wò ɖɔkta susui be ɖewohĩ pituitary adenoma le ŋuwò la, alé ŋku ɖe wò dzesiwo, wò atikewɔwɔ ŋutinya ŋu nyuie, eye wòado wò ŋutilã kpɔ. Tsɔ kpe ɖe eŋu la, woate ŋu akafu dodokpɔ siwo gbɔna la dometɔ ɖeka alo esi wu nenema:

Ʋudodokpɔ: Le wò dzesiwo nu la, woate ŋu abia be woado ʋu kpɔ be woalé ŋku ɖe lãmetsi vovovo siwo le lãkusi me ƒe agbɔsɔsɔ ŋu.
Nɔnɔmetatawo Dodokpɔwo: MRI (Magnetic Resonance Imaging) ƒe fotoɖeɖe le ta alo...CT (Computed Tomography) scan ateŋu akpɔ xɔtunu siwo le ta me ƒe nɔnɔmetata siwo me kɔ. Dodokpɔ siawo ate ŋu aɖo kpe edzi nenye be pituitary adenoma le eme kple alesi wòloloe. MRI dodokpɔ nye dodokpɔ si sɔ wu eye wòsea veve wu na esia.
Ŋkudodokpɔ: Ne ŋku ƒe kuxi aɖewo le ŋuwò la, wò ɖɔkta ate ŋu abia be woado ŋku ƒe dɔwɔwɔ kpɔ. Dodokpɔ sia le vevie elabena pituitary adenomas gãwo ate ŋu ahe ŋku ƒe kuxiwo vɛ to ŋku ƒe lãmeka si doa ka kple ŋkuwo kple ahɔhɔ̃a la tete me.

Aleke wodaa pituitary adenoma?

Mɔ vevi etɔ̃ li siwo dzi woato ada pituitary adenomas: amekoko, atikewo zazã, kple keklẽŋusẽdɔdamɔnu. Ɣeaɖewoɣi la, woate ŋu azã mɔnu siawo dometɔ ɖeka alo esi wu nenema ɖekae. Esi wònye be amesiame ƒe adenoma kple nɔnɔme to vovo ta la, wò kple wò atikewɔlawo ƒe ƒuƒoƒoa miate ŋu awɔ dɔ aduadu akpɔ atikewɔwɔ ƒe ɖoɖo si anyo na wò.

Amekoko be woaɖe adenoma ɖa

Ne adenoma aɖe le ŋuwò si le lãmetsiŋusẽ ƒe dadasɔ hem vɛ alo le ŋusẽ kpɔm ɖe wò ŋku dzi la, anɔ eme be wò ɖɔkta aɖo aɖaŋu be nàwɔ dɔ na wò atsɔ aɖe adenoma la katã alo eƒe akpa aɖe ɖa. Le adenoma la ƒe lolome kple alesi wò dzesiawo nu sẽe nu la, ate ŋu ahiã be woawɔ dɔ na wò wu zi ɖeka. Zi geɖe la, amekolawo zãa amekokomɔnu si woyɔna be Transsphenoidal Surgery tsɔ wɔa dɔ sia. Esia bia be woato ŋɔti me eye woato sphenoid sinus (teƒe si me do le le ŋɔti megbe, le ahɔhɔ̃a te) me be woaɖo pituitary gland gbɔ eye woaɖe adenoma la ɖa. Woɖea pituitary tumors siwo ade 95% ɖa to mɔ sia dzi. Enye dɔdamɔnu si me afɔku mele boo o. Gake ne adenoma la lolo akpa be woate ŋu aɖee to ŋɔti me alo ele teƒe si sesẽ la, ate ŋu ahiã be amekolaa nawɔ dɔ na amea to tagbɔ. Esia nye dɔdamɔnu si mebɔ o na pituitary adenomas.

Atikewo zazã

Woate ŋu aɖu pituitary adenomas ƒomevi aɖewo, vevietɔ prolactinomas , dzi ahaɖe wo dzi akpɔtɔ ne wozã atike. Wotsɔa dopamine agonist, abe Cabergoline (Dostinex®) alo Bromocriptine (Cycloset®) ene daa dɔ na amesiwo ŋu prolactinomas (esiawoe nye esiwo bɔ wu) gbã hena ɣleti geɖe.

Nya nyuiae nye be le dɔléle siwo ade 80% me la, atike siawo ɖea prolactinoma dzi kpɔtɔna eye wòtrɔa prolactin lãmetsiŋusẽ ƒe agbɔsɔsɔ ɖe nɔnɔme si sɔ me.

Ne atikewo mewɔ dɔ o alo ne adenoma ƒomevi bubue wònye la, wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ dɔ na wò.

Kekeli ƒe Dɔdamɔnu

Kekeli ƒe atikewɔwɔ zãa X-ray siwo ŋu ŋusẽ geɖe le tsɔ tsrɔ̃a adenoma lãmenugbagbeviwo, si wɔnɛ be dɔdzẽa dzi ɖena kpɔtɔna alo xea mɔ na eƒe tsitsi. Stereotactic Radiosurgery na Pituitary Adenomas(e.g. Gamma Knife®) Wozãa keklẽŋusẽ ƒe atikewɔwɔmɔnu tɔxɛ aɖe si sɔ pɛpɛpɛ ŋutɔ. Le esia me la, woɖoa keklẽŋusẽ ƒe keklẽ geɖe ɖe adenoma la ŋu tso mɔ vovovowo nu, si wɔnɛ be nusiwo gblẽna le lãmeka siwo le lãmesẽ me siwo ƒo xlãe ŋu dzi ɖena kpɔtɔna. Wozãa mɔnu sia na teƒe siwo susɔ le amekoko vɔ megbe alo le nɔnɔme siwo me amekoko mate ŋu adzɔ o me.

Nukawoe nye atikewɔwɔa ƒe nugbegblẽ le ame ŋu?

Abe alesi wòle le atikewɔwɔ ɖesiaɖe gome ene la, pituitary adenoma dada ate ŋu agblẽ nu le ame ŋu vie.

Le amekoko kple/alo keklẽŋusẽdɔdamɔnu megbe la, amesiwo ŋu pituitary adenomas le la dometɔ siwo ade 60% ateŋu axɔ Hypopituitarism (pituitary hormone ɖeka alo esi wu nenema ƒe wɔwɔme dzi ɖeɖe kpɔtɔ). Togbɔ be nɔnɔme sia nye agbemeŋkekewo katã ƒe nɔnɔme hã la, atike siwo woatsɔ aɖɔli lãmetsiŋusẽtikewo ate ŋu akpe ɖe amewo ŋu woanɔ agbe si sɔ.
Kuxi siwo ate ŋu ado tso amekoko me:
Ʋu si le dodom.
Cerebrospinal Fluid (CSF) leak (tsi si dona tso ŋɔti me).
Meningitis (dɔlékui si le lãkusi siwo tsyɔ ahɔhɔ̃a dzi).
Suklidɔ Insipidus (aɖuɖɔɖɔɖɔ fũ kple tsikɔwuame fũ le lãmetsi si tsia tsinyegoe me ƒe anyimanɔmanɔ ta).
Dopamine agonist atikewo ƒe nugbegblẽ le ame ŋu zi geɖe na prolactinoma dometɔ aɖewoe nye: taɖuame, ʋuʋudedi, ʋuʋudedi, taɖuame, kple ɣeaɖewoɣi nuwɔna siwo nye dzizizi.
Nusiwo ate ŋu ado tso keklẽŋusẽdɔdamɔnu me:
Pituitary hormone ƒe anyimanɔmanɔ (ate ŋu adzɔ le ɣeyiɣi aɖe megbe).
Vidzidzi ƒe Dɔmawɔmawɔ nyuie.
Nukpɔkpɔ ƒe bu kple ahɔhɔ̃mekawo ƒe gbegblẽ (si ƒã ŋutɔ).
Dɔdzẽ bubu ate ŋu ado mo ɖa le teƒe ma ke le ƒe geɖe le atikewɔwɔ vɔ megbe (si mebɔ kura o).

Ðe woate ŋu axe mɔ ɖe adenoma siawo ƒe wɔwɔ nua?

Nublanuitɔe la, naneke meli nàte ŋu awɔ atsɔ axe mɔ ɖe pituitary adenomas nu o. Zi geɖe la, wodzɔna le vome. Gake woate ŋu ado ƒome kple domenyiŋusẽfianu ƒe nɔnɔme siwo mebɔ o siwo ŋu míeƒo nu tsoe va yi la dometɔ aɖewo. Ne domenyiŋusẽfianu ƒe dɔléle aɖe le ƒometɔ kplikplikpli aɖe (nɔviŋutsu, nɔvinyɔnu, alo dzila) ŋu abe esia ene la, àte ŋu aƒo nu kple wò ɖɔkta tso domenyiŋusẽfianu ŋuti aɖaŋuɖoɖo kple dodokpɔ ŋu akpɔe ɖa be dɔlélea le ŋuwò hã. Ne èwɔe alea la, wò ɖɔkta ate ŋu alé ŋku ɖe ŋuwò nyuie eye wòade dzesi adenoma ɖesiaɖe si doa mo ɖa kaba ahadae.

Nukae nye nɔnɔme sia ƒe ŋgɔdonya?

Mɔkpɔkpɔ na pituitary adenoma, si fia be wò hayahaya kple wò lãmesẽ le etsɔme, nɔ te ɖe adenoma ƒe lolome kple eƒe ƒomevi dzi, kple atike si woawɔ na wò dzi .

Nya nyuiae nye be zi geɖe la, ne woɖe adenoma la ɖa keŋkeŋ alo tsɔ atikewɔwɔ ɖu edzi la, dɔnɔwo ate ŋu anɔ agbe blibo si me lãmesẽ le ake.

Le go aɖewo me la, atikewɔwɔ ate ŋu aɖe lãmetsi siwo le lãkusia me dzi akpɔtɔ. Ne edzɔ alea la, ɖewohĩ ahiã be nàno lãmetsiŋusẽtikewo le wò agbemeŋkekewo katã me be woatsɔ aɖɔli lãmetsiŋusẽ siwo dzi ɖe kpɔtɔ. Adenomas ate ŋu agadzɔ ake ɣeaɖewoɣi. Esia fia be ɖewohĩ ahiã be woagawɔ atike na wo le ɣeyiɣi aɖe megbe. Akɔntabubuwo ɖee fia be amesiwo ŋu adenomas siwo mewɔa dɔ o le dometɔ siwo ade 18% kple amesiwo ŋu prolactinoma le ƒe abe 25% ate ŋu agahiã atikewɔwɔ ake le etsɔme. Eyata ele vevie ŋutɔ be nànɔ kadodo me kple wò ɖɔkta edziedzi eye nànɔ dodokpɔ wɔm edziedzi.

Ðe wòanya wɔ be woanɔ agbe kple pituitary adenoma?

Ẽ, àte ŋui. Ne pituitary adenoma le sue eye mehe dzesi aɖeke vɛ o la, àte ŋu anɔ agbe kplii abe alesi wòle ene. Le nyateƒe me la, ne wowɔ ta na yewo le susu bubu aɖe ta ko hafi ame geɖe nya be adenoma le yewo ŋu. Gake ne adenoma la yi edzi le tsitsim alo dze dzesiwo hehe vɛ la, ahiã be woawɔ atike na wò godoo. Ne pituitary adenoma gã aɖe kple/alo si le dɔ wɔm (si wɔa lãmetsiŋusẽ) le ŋuwò la, ahiã be woawɔ atike na wò godoo. Esia le alea elabena pituitary adenomas aɖewo ate ŋu akpɔ ŋusẽ gã aɖe ɖe wò lãmesẽ kple agbenɔnɔ ƒe nyonyome dzi.

Kuxi kawoe ate ŋu ado mo ɖa ne womewɔ atike nɛ o?

Ne womewɔ atike na wo o la, pituitary adenomas aɖewo – vevietɔ adenomas gãwo (Macroadenomas) kple functional (Secreting) adenomas – ateŋu ahe lãmesẽkuxi sesẽwo vɛ . Lãmesẽkuxi siawo nɔ te ɖe lãmetsi ƒomevi si adenoma la ɖena ɖe go dzi koŋ (míeƒo nu tso esia ŋu do ŋgɔ le akpa si nye Dzesiwo me). Kuxi si mebɔ kura o gake afɔku le eme ŋutɔ le pituitary adenomas siwo womeda dɔ na o ŋue nye Pituitary Apoplexy. Esia nye Atikewɔwɔ Kpata. Esia dzɔna ne ʋu le dodom le ʋuka si me ʋu sina tona me alo dona le eme. Pituitary Apoplexy tsoa ʋu si dona le pituitary adenoma me gbɔ zi geɖe. Kasia dɔdzẽa lolona, si gblẽa nu le lãkusi si le lãkusia me ŋu. Zi alesi adenoma la loloe la, zi nenemae afɔku si le Pituitary Apoplexy xɔxɔ me la lolonae. Zi geɖe la, Pituitary Apoplexy ƒe dzesiwo dzena kabakaba ŋutɔ eye woate ŋu ade ame ƒe agbe afɔku me . Dzesi vevitɔwoe nye:

Taɖuame sesẽ aɖe ŋutɔ (abe taɖuame vɔ̃ɖitɔ kekeake si mekpɔ le nye agbe me ene).
Nukpɔkpɔ zi eve alo ŋkume ƒe ʋuʋu ƒe ŋutetemanɔamesi le ŋku ƒe lãmekawo ƒe dɔmawɔmawɔ nyuie ta.
Axadzinukpɔkpɔ ƒe bu alo ŋku ɖeka alo evea siaa ƒe nukpɔkpɔ keŋkeŋ.
Adrenal insufficiency kpata nana ʋu ƒe sisi dzi ɖena kpɔtɔna, ʋuʋudedi, kple ʋuʋudedi.
Amenyenye ƒe tɔtrɔ (e.g., tɔtɔ) le ahɔhɔ̃meka si le ŋgɔgbe ƒe ʋuʋu kpata le ahɔhɔ̃a me ta.

Pituitary apoplexy nye dɔléle si mebɔ o, gake esesẽ ŋutɔ. Ne èkpɔ dzesi siawo dometɔ ɖeka alo esi wu nenema la, ƒo ka na atikewɔƒe siwo kpɔa nudzɔdzɔ kpatawo gbɔ (abe 911 ene) enumake alo nàna ame aɖe nakplɔ wò ayi kɔdzi ƒe xɔ si te ɖe ŋuwò kpata.

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

Ne ŋku ƒe kuxi aɖewo le ŋuwò (nukpɔkpɔ me mekɔ o, nukpɔkpɔ zi eve, nukpɔkpɔ le gota gome ƒe ɖiɖi) kple/alo taɖuame si nɔa anyi ɖaa alo gbugbɔna (vevietɔ le ŋgonu ƒe akpa si) la, yi ɖɔkta gbɔ eye nàgblɔe na wo.
Ne wokpɔe be pituitary adenoma le ŋuwò xoxo la, ahiã be nàyi ɖɔkta gbɔ edziedzi be nàlé ŋku ɖe adenoma ƒe nɔnɔme ŋu eye nàkpɔ egbɔ be atikewɔwɔa le dɔ wɔm nyuie.

Mlɔeba la, ɖo ŋku nu siawo dzi:

Enye nusi sɔ ŋutɔ be vɔvɔ̃ kple dzimaɖitsitsi ne èva nya be dɔdzẽ le ye ŋu. Gake nya nyui si le pituitary adenomas ŋue nye be woƒe akpa gãtɔ (si wu 99%) menye kansa o (siwo menyo o) eye le go geɖe me la, atikewɔwɔ ate ŋu ahe nu nyui ŋutɔ vɛ. Ðo ŋku edzi be wò ɖɔktae nye wò zɔhɛ le wò lãmesẽ nyuitɔ kekeake gbɔ ɖoɖo me. Eyata mègahe ɖe megbe gbeɖe be nàna wò ɖɔkta nanya nu tso dɔlélea ƒe dzesiwo, veveseseɖeamenu, alo nyabiase aɖeke si anɔ asiwò ku ɖe wò atikewɔwɔ ŋu la ŋu o. Ne ènya nyatakaka nyuitɔ eye nèdae ɖe game dzi la, àte ŋu akpɔ nɔnɔme sia gbɔ dzidzedzetɔe godoo.

Ðe dɔdzẽ aɖe le wò ʋuka si me ʋu sina tona ŋua? (Pituitary Adenoma) Mina míasrɔ̃ nu tso eŋu!