Nukae nye Thymoma kple Thymic Carcinoma? Mina míaƒo nu tso esia ŋu tsitotsito!

Ðe nèsena le ɖokuiwò me ɣeaɖewoɣi be nane si wɔ nuku le yeƒe akɔta, kɔdzidɔ si nu metsina o, alo gbɔgbɔ sesẽna na yea? Zi geɖe la, nusiawo ate ŋu atso susu siwo sɔ, siwo megblẽa nu le ame ŋu o gbɔ. Gake ƒã ŋutɔ la, esiawo ate ŋu anye kansa si do ƒome kple thymus gland hã ƒe dzesiwo . Eyata, egbea míele nu ƒom tso kansa ƒomevi eve siawo tɔgbe, siwo mebɔ kura o, siwo nye Thymoma kple Thymic Carcinoma ŋu. Mègatsi dzi o, ele vevie ŋutɔ be nànya esia.

Nukae nye Thymoma kple Thymic Carcinoma?

Kpuie ko la, thymoma kple thymic carcinoma nye kansa ƒomevi eve siwo dzea egɔme tso wò thymus gland me . Thymus gland la le ƒu gã si le wò akɔta titina (no me ƒu) la megbe. Ne ènye ɖekakpui la, thymus gland kpena ɖe ame ŋu be T-lymphocytes, alo T-cells, si nye ʋumenugbagbevi ɣi ƒomevi aɖe si nye wò ŋutilã ƒe dɔlélenutsiŋutete ƒe akpa vevi aɖe si wɔa avu kple dɔlélewo la dona. Lãmenugbagbevi ƒomevi vevi eve le thymus gland la me: lãmenugbagbevi siwo le lãkusi me kple ʋumenugbagbevi dzĩwo . Lãmenugbagbevi siawo dometɔ ɖesiaɖe ate ŋu atsi le mɔ si mesɔ o nu eye wòazu kansa.

• Thymoma kple thymic carcinoma tsoa lãmenugbagbevi siwo le lãkusi me ƒe tsitsi si mesɔ o gbɔ.
• Lãmetsiŋusẽ ƒe tsitsi si mesɔ o ate ŋu ahe kansa abe Hodgkin ʋumenugbagbeviɣidɔ alo non-Hodgkin ʋumenugbagbeviɣidɔ ene vɛ.

Esi wònye be thymomas kple thymic carcinomas siaa dzea egɔme tso thymus gland ƒe lãmenugbagbeviwo me ta la, ɖɔktawo yɔa wo hã be Thymic Epithelial Tumors (TETs) .

Vovototo kae le Thymoma kple Thymic Carcinoma dome?

Togbɔ be wo ame evea siaa nye thymic epithelial tumors (TETs) hã la, vovototo vevi geɖe le wo dome.

• Thymoma: Zi geɖe la, esia nyea kansa si tsina blewu . Ƒã hafi wòkakana yia ŋgɔ wu thymus gland.
• Thymic Carcinoma: Esia nye kansa si le dzidzim ɖe edzi kabakaba . Mɔnukpɔkpɔ gã aɖe hã li be wòakaka (metastasizing) ɖe ŋutilã ƒe akpa bubuwo.

Le nenye be thymoma (si ƒe ƒomevi mesẽna vie o) alo thymic carcinoma (si me dziku le wu) le ŋuwò ta la, atike si wò ɖɔkta aŋlɔ na wò kple alesi nàgblɔe ɖi la ato vovo.

Amekawoe nɔnɔme siawo gblẽa nu le wu?

Thymoma kple thymic carcinoma bɔ ɖe ame tsitsi siwo xɔ tso ƒe 40 va ɖo ƒe 75. Numekuku siwo wowɔ le dukɔwo abe United States ene me ɖee fia be dɔlélea bɔ ɖe amesiwo tso Asia alo Pasifik Ƒukpowo dzi wu me. Ke hã, ele vevie be míaɖo ŋku edzi be ate ŋu adze ame sia ame dzi. Zi geɖe la , thymoma do ƒome kple nɔnɔme siwo woyɔna be autoimmune paraneoplastic syndromes . Esiae nye ne wò ŋutilã ƒe dɔlélenutsiŋutete dze eya ŋutɔ ƒe lãmenugbagbevi siwo le lãmesẽ me dzi vodadatɔe. Esia ate ŋu ahe dzesi vovovo siwo me dzidzeme mele o vɛ. Dɔléle siwo do ƒome kple thymoma wu dometɔ aɖewoe nye:

• Myasthenia gravis: Esia nye dɔléle si tsoa dɔlélenutsiŋutete gbɔ si gblẽa nu le lãmekawo kple lãmekawo ŋu, si wɔnɛ be lãmekawo gbɔdzɔna .
• Pure red cell aplasia (PRCA): Esia nye ʋumenugbagbeviɣidɔ si me wò ƒumeŋuɖui mewɔa ʋumenugbagbevi dzĩwo wòsɔ gbɔ o , si nana ʋusɔgbɔdɔ .
• Hypogammaglobulinemia (alo Good syndrome): Esia nye dɔlélenutsiŋutete ƒe gbɔdzɔgbɔdzɔ. Le afisia la, wò ŋutilã mewɔa dɔlékuiwutike siwo sɔ be woatsɔ awɔ avu kple dɔléle ahaxe mɔ ɖe dɔlékuiwo xɔxɔ nu o.

Tsɔ kpe ɖe eŋu la, paraneoplastic syndrome bubu aɖewo ate ŋu ado ƒome kple thymoma, gake womebɔ o. Le kpɔɖeŋu me:

• Polymyositis ƒe dɔléle
• Lupus si nye ʋumenugbagbeviɣidɔ
• Lãmetsiŋusẽ ƒe ƒunukpeƒetetedɔ
• Thyroiditis ƒe dɔléle
• Sjögren ƒe dɔlélea

Aleke gbegbee thymoma kple thymic carcinoma bɔe?

Thymoma kple thymic carcinoma ye nye kansa ƒomevi siwo bɔ wu siwo dona le thymus gland me. Gake le nusianu me la, esiawo nye kansa siwo mebɔ kura o . Le kpɔɖeŋu me, le dukɔ gã aɖe abe United States ene gɔ̃ hã me la, ame siwo ade 400 koe woxɔa dɔléle sia ƒe sia ƒe.

Nukae nye thymoma kple thymic carcinoma ƒe dzesiwo?

Ame geɖe meɖea dzesi aɖeke fiana le eƒe gɔmedzedze o.Zi geɖe la, dzesiawo dzea egɔme ne kansa la tsi eye wòdze akɔta ƒe ŋutinu bubuwo dzi kpɔkpɔ gɔme. Dzesiawo dometɔ aɖewo do ƒome kple paraneoplastic syndromes siwo míeyɔ va yi.

Dzesi siwo kansa si gblẽa nu le akɔta ƒe ŋutinu aɖe ŋu hena vɛ

Vevesese kple gbɔgbɔ sesẽ ate ŋu anye thymoma alo thymic carcinoma ƒe dzesiwo. Esiawoe nye dzesiawo:

• Akɔtave alo akɔta ƒe ʋuʋu ƒe seselelãme.
• Kɔdzidede si nu metsina o si nu meyina o.
• Yagbɔgbɔ kpuie.
• Nuɖuɖu mimi sesẽ.

Ɣeaɖewoɣi la, dɔdzẽ siawo te ŋu xea mɔ na vena cava si le dzi wu, si nye ʋuka gã aɖe si tsɔa ʋu yia dzia gbɔ alo mia wo. Esia ate ŋu ahe nɔnɔme sesẽ aɖe ŋutɔ si woyɔna be superior vena cava syndrome vɛ . Ne edzɔ alea la, àte ŋu akpɔ dzesiwo abe:

• Kpe
• Yagbɔgbɔ sesẽ
• Ɖeɖiteameŋu
• Taɖuame
• Taɖuame
• Kɔ kple mo ƒe vuvu
• Asiwo kple asibidɛwo ƒe vuvu
• Ʋuka siwo dzena nyuie le ŋutilã ƒe akpa si le etame

Paraneoplastic syndromes ƒe nɔnɔmewo

Ne thymoma le ŋuwò la, àte ŋu akpɔ paraneoplastic syndromes ƒe dzesi ɖeka alo esi wu nenema. Le kpɔɖeŋu me:

• Nukpɔkpɔ zi eve, ŋkume ƒe ʋuʋu, ɖeɖiteameŋu vevie, kple lãmekawo ƒe gbɔdzɔgbɔdzɔ (esiawo nye myasthenia gravis ƒe dzesiwo).
• Ʋusɔgbɔdɔ (esia ate ŋu atso ʋumenugbagbevi dzĩ dzadzɛwo ƒe aplasia gbɔ).
• Dɔlékuiwo xɔxɔ enuenu, aɖuɖɔtoe, kple ʋuka siwo vuvu (esiawo nye hypogammaglobulinemia ƒe dzesiwo).

Nukawoe hea thymoma (thymic carcinoma) vɛ?

Le nyateƒe me la, womede dzesi domenyiŋusẽfianu alo nutome ƒe afɔku aɖeke koŋ na thymoma o . Wogale numekuku wɔm be woakpɔe ɖa be dɔlélea do ƒome kple dɔlékui vovovowo, domenyiŋusẽfianu ƒe ŋusẽkpɔɖeamedziwo, kple kansa ƒomevi bubuwo hã.

Aleke wowɔa dea dzesi thymoma (thymic carcinoma)? (Dɔléle ƒe dzesi) .

Ðewohĩ ne èwɔ nɔnɔmetatawo dodokpɔ be yeadi nusi gbɔ wò dzesiawo tso vɔ ko hafi wò ɖɔkta akpɔe be dɔdzẽ sia ƒomevi le ŋuwò. Be nàɖo kpe dɔlélea dzi la, wò ɖɔkta awɔ wò ŋutilã dodokpɔ ahabia wò dzesiwo kple wò atikewɔwɔ ŋutinya. Emegbe, woate ŋu awɔ dodokpɔ siwo gbɔna la dometɔ ɖeka alo esi wu nenema be woanya nu geɖe tso dɔdzẽa ŋu:

• Akɔta ƒe X-ray: X-ray ate ŋu aɖe nuwo abe dɔdzẽ siwo le ŋutilãa me ene afia. Ate ŋu ana nyatakaka veviwo hã, abe alesi woɖe dɔdzẽa ƒe goawo me nyuie ene. Dɔdzẽ si ƒe gowo me kɔ la ɖeɖe ɖa le amekoko me bɔbɔe wu.
• CT-dɔdamɔnu:Akɔta ƒe CT-dɔdamɔnue nye nɔnɔmetata dodokpɔ si wozãna wu tsɔ dea dzesi thymoma. Ɣeaɖewoɣi la, wò ɖɔkta ate ŋu ado tsi tɔxɛ aɖe (contrast medium) wò ʋuka me. Esia akpe ɖe dɔdzẽa ŋu wòadze nyuie le fotoɖeɖea me. Zi geɖe la, CT-dɔdamɔnu sɔ gbɔ be woatsɔ anya thymoma alo thymic carcinoma.
• MRI scan: MRI ate ŋu awɔ dɔdzẽa ƒe nɔnɔmetata siwo me kɔ ŋutɔ. Esia ate ŋu akpe ɖe ɖɔktaa ŋu wòade vovototoe tso tsitsi ƒomevi bubuwo gbɔ. Le kpɔɖeŋu me, MRI ate ŋu akpe ɖe ame ŋu wòanya nenye be thymoma alo thymic carcinoma ye.
• PET scan alo PET/CT scan: Le PET scan wɔwɔ me la, ɖɔkta doa sukli si le dedie, si me keklẽŋusẽ le ɖe wò ʋuka me. Atike sia ƒoa ƒu ɖe lãmenugbagbevi siwo zãa ŋusẽ geɖe, abe kansa lãmenugbagbeviwo ene, ŋu. Esia wɔnɛ be nuwo abe dɔdzẽ ene dzena nyuie wu le fotoɖeɖea me. Zi geɖe la, woate ŋu awɔ PET scan kple CT scan le ɣeyiɣi ɖeka me (PET/CT).
• Biopsy: Mɔ ɖeka kolia si dzi woato aɖo kpe dɔléle aɖe dzi godooe nye be woawɔ biopsy. Afi siae ɖɔktaa xɔa lãmenugbagbeviwo ƒe kpɔɖeŋu tso dɔdzẽa me hedoa wo kpɔna le nusuekpɔmɔ̃ me. Ne esia wɔwɔ mele dedie o la, ɖɔktaa aɖe dɔdzẽ bliboa ɖa eye wòado lãmenugbagbeviawo kpɔ. Ne womate ŋu aɖe dɔdzẽ bliboa ɖa o la, woaɖe eƒe kpɔɖeŋu ɖeka ko atsɔ adoe kpɔ.

Aleke wowɔna nyaa afisi thymoma (thymic carcinoma) le?

Kansa ƒe ɖoɖoe nye kansa ƒe hatsotsowo me toto le eƒe sesẽ nu. Nu geɖe yia edzi le dɔlélea ƒe sesẽme nyanya me. Ne ènya afisi wò kansa le la, ekpena ɖe wò ɖɔkta ŋu wòwɔa ɖoɖo ɖe atikewɔwɔ ŋu eye wònana nèkpɔa mɔnukpɔkpɔ si li be nàtsi agbe. Wozãa TNM ƒe ɖoɖoa tsɔ ɖoa ​​thymoma kple thymic carcinoma ɖe ɖoɖo nu . TNM tsi tre ɖi na Tumor, Nodes, kple Metastasis. Be ɖɔktawo nanya afisi wò kansa le la, dia ŋuɖoɖo na nyabiasewo abe:

• Tumor (T): Ðe tumor aɖe li? Aleke gbegbee wòloloe? Afikae wòle?
• Lymph Nodes (Nodes - N): Ðe kansa la kaka ɖe ʋukawo mea? Lãmetsiŋusẽ kawoe? Afikae wòkaka ɖo?
• Metastasis (M): Ðe kansa la kaka ɖe ŋutilã ƒe akpa bubuwo le thymus gland godoa? Akpa kawo gbɔe?

Wò ɖɔkta anɔ te ɖe biabia siawo ƒe ŋuɖoɖowo dzi ama wò kansa ɖe hatsotso siwo tso I (ɖeka) va ɖo IV (ene) me. Zi alesi xexlẽmea sɔ gbɔe la, zi nenemae kansa la kakae. Le kpɔɖeŋu me, kansa si le afɔɖeɖe I me kaka mede kansa si le afɔɖeɖe IV me o. Wò ɖɔkta ate ŋu abu nu bubuwo hã ŋu, abe alesi kansadɔlékuiawo mesɔ o ene, be yeanya alesi wò dɔlélea nu sẽe.

Nukawoe nye atike siwo wozãna na thymoma (thymic carcinoma)?

Atike si nàxɔ la nɔ te ɖe nu geɖe dzi, siwo dometɔ aɖewoe nye kansa ƒomevi si le ŋuwò, afisi kansa la le, kple nenye be wokpɔ kansa la yeyee alo egadzɔ ake. Atikewɔwɔ ƒe tiatia ate ŋu anye:

• Amekoko: Akɔtadɔdala ate ŋu aɖe wò dɔdzẽa ɖa to amekoko me. Ne kansa la kaka ɖe ʋukawo, thymus gland, alo lãkusi me la, woate ŋu aɖe eƒe akpa aɖewo hã ɖa. Amekokoe nye atike vevitɔ na thymoma si le eƒe gɔmedzedze. Ne womate ŋu aɖe dɔdzẽ bliboa ɖa dedie o la, amekolaa aɖe eƒe akpa gãtɔ alesi wòate ŋui be wòaɖe dzesi siwo dɔdzẽa hena vɛ dzi akpɔtɔ.
• Kekeli ƒe atikewɔwɔ: Kekeli ƒe kansadɔdala ate ŋu atsɔ keklẽŋusẽ ayi kansa la gbɔ to gotagome keklẽŋusẽ zazã me . Dɔdamɔnu sia zãa mɔ̃ aɖe tsɔ fiaa mɔ X-ray ɖe dɔdzẽa ŋu be wòawu kansa lãmenugbagbeviwo. Woate ŋu azãe ɖeɖeko alo atsɔe akpe ɖe atikewɔmɔnu bubuwo abe atikewɔmɔnu alo amekoko ene ŋu.
• Atikewɔwɔ: Ne amekoko mete ŋu ɖe dɔdzẽa ɖa o la, woate ŋu ana atike siwo woatsɔ awu kansadɔlékuiwo wò. Ʋuŋutinunyala alo kansadɔdala ate ŋu aŋlɔ atike na ame be wòaɖe dɔdzẽa dzi akpɔtɔ hafi awɔ dɔ nɛ alo atsɔ ada kansa si gagbɔ va.
• Atikewɔwɔ si woɖo taɖodzinu na: Ne domenyiŋusẽfianu ƒe tɔtrɔ aɖewo koŋ le wò kansa lãmenugbagbeviwo ŋu , woate ŋu ana atike si woɖo taɖodzinu na wò. Wotrɔ asi le atikewɔwɔ siawo ŋu be woatsɔ aɖo domenyiŋusẽfianu ƒe tɔtrɔ tɔxɛ mawo gbɔ eye woawu kansadɔlékuiawo. Esia ate ŋu anye atike si woate ŋu azã na thymoma kple thymic carcinoma siaa ne atikewɔwɔ bubuwo, abe atikewɔmɔnu ene, mewɔ dɔ o.
• Dɔlélenutsiŋutete ƒe dɔdamɔnu: Dɔdamɔnu sia doa ŋusẽ wò dɔlélenutsiŋutete be wòakpe ɖe eŋu wòade dzesi kansa lãmenugbagbeviwo ahagblẽ wo dome. Esia ate ŋu anye tiatia na thymic carcinoma si mele dɔ wɔm na atikewɔmɔnu o.
• Dɔdamɔnu dodokpɔwo: Dɔdamɔnu dodokpɔ nye numekuku si doa kansadɔdamɔnu yeyewo alo vovovowo ƒe dedienɔnɔ kple dɔwɔwɔ kpɔna. Le wò kansa ƒomevi nu la, àte ŋu adze na ɖoɖo siawo dometɔ ɖeka si doa kansadɔdamɔnu yeyewo kpɔna. Bia wò ɖɔkta tso esia ŋu.

Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ dɔ kple atikewɔha aɖe si kpɔa dɔdzẽ dzi be wòado alɔ wò le wò kansa didi katã me. Ðɔktawo, dɔnɔdzikpɔlawo, kple eŋutinunyala bibi bubuwo dometɔ aɖewoe nye ɖɔktawo, dɔnɔdzikpɔlawo, kple eŋutinunyala bibi bubuwo. Woate ŋu akpe ɖe ŋuwò nàkpɔ kansa ƒe dzesiwo kple atikewɔwɔ ƒe nugbegblẽ le ame ŋu gbɔ. Aleke kee wò kansa ƒe afɔɖeɖe ka kee ɖale o alo mɔnukpɔkpɔ si li be nàhaya o, beléle si naa ame ƒe dzi dzea eme nye dɔwɔnu vevi aɖe.

Nukae nye agbetsitsi ƒe agbɔsɔsɔme le thymoma kple thymic carcinoma me?

Le goawo katã me la, thymomas ƒe ŋgɔdonya nyo wu thymic carcinomas. Azɔ hã, ne thymus gland koe kansa la le la, agbetsitsi ƒe agbɔsɔsɔme nyo wu ne kansa la kaka. Ƒe atɔ̃ ƒe agbetsitsi le thymic carcinoma ŋue nye esiawo (ɖo ŋku edzi be esiawo nye xexlẽme siwo le mama dedie nu):

• Ne kansa la le thymus gland me ko la: 95% .
• Ne ekaka ɖe ŋutinu kple ʋuka siwo te ɖe eŋu me la: 78% .
• Ne ekaka ɖe ŋutilã ƒe akpa siwo le didiƒe (metastasized): 38% .

Gake akɔntabubu siawo mebua nu aɖewo koŋ abe wò lãmesẽ bliboa, kansa ƒomevi, afisi kansa la le, alo alesi nèwɔa nui ɖe atikewɔwɔ ŋu ene ŋu o. Nu geɖee fiaa alesi nàtsi agbee. Wò ɖɔkta ate ŋu aɖe nusiawo me na wò. Eyata xexlẽdzesi siawo megavɔ̃ o.

Nukae mate ŋu akpɔ mɔ na ne kansa sia le ŋunye?

Le go aɖewo me la, kansa ƒe dzesiwo kple dzesiwo katã ate ŋu nu ayi keŋkeŋ (remission) , eye kansa la magatrɔ ava o. Gake le go geɖe me la, kansa ƒomevi evea siaa ate ŋu atrɔ ava (gbugbɔgadzɔ) . Le thymoma gome la, kansa la ate ŋu ayi edzi ɣeyiɣi didi aɖe evɔ magatrɔ ava o. Gake ahiã kokoko be nàva srã wò kpɔ edziedzi be nàka ɖe edzi be kansa mele ye ŋu o.

Nya kawoe wòle be mabia nye ɖɔkta?

Ðo dze kple wò atikewɔlawo ƒe ƒuƒoƒoa tso wò dɔlélea didi kple atikewɔmɔnu siwo nàte ŋu azã ŋu. Mègahe ɖe megbe le nya ɖesiaɖe si le asiwò ku ɖe kansa kple alesi wòakpɔ ŋusẽ ɖe wò agbe dzii ŋu biabia o. Àte ŋu abia nyawo abe:

• Afikae nye kansa la le?
• Atikewɔwɔmɔnu kawoe le asinye?
• Ðe medze akpɔ gome le dɔdamɔnu dodokpɔ aɖe mea? Àkafui be makpɔ gome le emea?
• Nukae nye atikewɔwɔ ƒe taɖodzinu?
• Nu gbegblẽ kawoe wòle be makpɔ mɔ na?
• Ɣekaɣie wòle be makpɔ mɔ be eƒe nugbegblẽ le ame ŋu adze egɔme?
• Mɔnukpɔkpɔ kae li be kansa la nagatrɔ ava?
• Aleke dɔléle si wokpɔ le ŋunye kple alesi woawɔ atike nam akpɔ ŋusẽ ɖe nye agbe dzii?

Gbedasi si Wotsɔ Yi Aƒeme

Ne wokpɔ thymoma alo thymic carcinoma la, ate ŋu afia nu vovovo geɖe. Dɔdzẽ aɖewo tsina vivivi, gake bubuwo ya nu sẽna wu. Woate ŋu aɖe wo dometɔ aɖewo ɖa keŋkeŋ ne wowɔ dɔ na wo, gake ɖewohĩ bubuwo kaka hafi wò ɖɔkta nava ke ɖe wo ŋu. Nu vevitɔe nye be nàƒo nu kple wò ɖɔkta tso alesi wò kansa akpɔ ŋusẽ ɖe wò atikewɔwɔ me tsonu dzii ŋu.Ƒo nu tso viɖe kple kuxi siwo le atikewɔwɔ ɖesiaɖe si nàte ŋui ŋu hã me. Ðo ŋku edzi be menye wò ɖeka koe o. Ðɔktawo, ƒometɔwo, kple xɔlɔ̃wo li siwo ate ŋu akpe ɖe ŋuwò nànɔ te ɖe nɔnɔme sia nu. Ele vevie be nànya nu tso eŋu nyuie ahanɔ susu nyuiwo bum. Ne nya aɖe le asiwò la, mègavɔ̃ be yeabia wò ɖɔkta o. ` thymoma, thymic carcinoma, thymus gland, kansa, akɔtave, kɔdzi, myasthenia gravis, autoimmune, kansa dada, kansa, thymoma, thymus carcinoma, thymus gland