He puʻupuʻu ʻē paha kou ma kou kino? He (Hamartoma) paha ia! E kamaʻilio kākou e pili ana i kēia.

Ua ʻike anei ʻoe i kahi puʻupuʻu liʻiliʻi a i ʻole kahi puʻupuʻu ma kekahi wahi o kou kino a noʻonoʻo, "He aha kēia?" A i ʻole ua noʻonoʻo paha ʻoe i ke ʻano o ka wā i kapa ai ke kauka iā ʻoe he "Hamartoma"? He aha maoli kēia "Hamartoma"? E kamaʻilio maʻalahi kākou e pili ana iā ia, ma ke ʻano e hiki ai iā ʻoe ke hoʻomaopopo.

He aha ka `(Hamartoma)`? E hoʻomaopopo maʻalahi kākou!

ʻAe, e nānā kākou i kēia ʻano `(Hamartoma)`. I ka ʻōlelo maʻalahi, he puʻupuʻu liʻiliʻi a maikaʻi ʻole ia. Hoʻokumu ʻia ia mai nā ʻano like o nā cell i loaʻa maʻamau i loko o ko kākou kino. Akā aia kahi ʻokoʻa iki. ʻO ia hoʻi, hui pū kēia mau cell ma ke ʻano ʻano ʻē a hoʻonohonoho ʻole ʻia e hana i kēia puʻupuʻu. Ua like ia me ke kau ʻana i kekahi o nā ʻano mea pāʻani like i loko o kahi puʻu ma kahi o ke kau ʻana iā lākou ma ke ʻano hoʻonohonoho. Loaʻa ka huaʻōlelo `(Hamartoma)` mai ʻelua mau huaʻōlelo Helene. ʻO ``Hamartia`` ʻo ia hoʻi ``hewa`` a i ʻole ``hema``. ʻO ``Oma`` ʻo ia hoʻi ``puʻupuʻu``. No laila, ʻo ia hoʻi kahi puʻupuʻu e ulu ana ma muli o kekahi ʻano kīnā.

ʻO ka mea nui loa, ʻaʻole kēia mau "Hamartomas" he maʻi kanesa . ʻAʻole lākou e laha ma ke kino e like me nā hunaola kanesa . No laila, ʻaʻohe mea e hopohopo ai. Eia nō naʻe, ma muli o ko lākou wahi, hiki iā lākou ke hana i nā pilikia liʻiliʻi i kekahi manawa.

Ma hea i loko o ke kino e hiki ai i kēia `(Hamartoma)` ke ulu?

Hiki i kēia mau "Hamartomas" ke hana ma nā wahi āpau o ko mākou kino. Akā aia kekahi mau wahi i ʻike pinepine ʻia ai lākou.

• Nā Māmā : ʻO ka hapa pinepine, ulu kēia mau "Hamartomas" i loko o nā māmā. ʻO 10% wale nō o nā puʻupuʻu maikaʻi i loaʻa i loko o nā māmā i ʻōlelo ʻia he ʻano kēia. I kekahi manawa, ʻike ʻia lākou i ka wā i lawe ʻia ai kahi " X-ray" umauma no kekahi kumu ʻē aʻe.
• ʻIli: Loaʻa pinepine ʻia nā Hamartomas ma ke poʻo a me ka ʻāʻī, ʻoi aku hoʻi ma ka maka, nā lehelehe, a ma hope a ma lalo o nā pepeiao. I kekahi manawa e like paha lākou me nā māka hānau.
• Puʻuwai : Hiki i kēia mau mea ke ulu i loko o ka puʻuwai. ʻO ka cardiac rhabdomyoma kahi ʻano hamartoma kakaʻikahi e ulu ana i loko o ka puʻuwai. Loaʻa pinepine kēia mau mea i loko o ka ʻōpū o ka makuahine (i ka wā hāpai ) a i ʻole he pēpē liʻiliʻi. ʻOiai he kakaʻikahi, ʻo ia nā puʻupuʻu maʻamau e ulu ana i loko o ka puʻuwai o nā keiki ʻōpio.
• Lolo:Hoʻomohala ʻia kahi ʻano puʻupuʻu i kapa ʻia he hypothalamic hamartoma i loko o ka hypothalamus, kahi ʻāpana o ka lolo e kōkua i ka hoʻoponopono ʻana i nā kaʻina hana koʻikoʻi he nui i loko o ke kino. Hiki ke loaʻa kēia mau puʻupuʻu i ka wā hānau, akā hōʻike pinepine lākou i nā hōʻailona i ka wā kamaliʻi a i ʻole ka wā ʻōpio. Hiki iā lākou ke hana i nā hōʻailona e like me nā hopu ʻana , nā pilikia ʻike , a me ka wā ʻōpiopio mua.
• ʻŪmaʻi: Ma kahi o 5% o nā puʻupuʻu maikaʻi ʻole i loko o nā ʻūmaʻi o nā wahine he hamartomas paha. ʻOi aku ka maʻamau o lākou i nā wahine ma luna o 35 mau makahiki.

Eia kekahi, hiki i nā hamartomas ke ulu ma nā wahi e like me nā puʻupaʻa, ka spleen, ka thyroid gland, a me nā iwi, e pili ana i kekahi mau kūlana genetic e like me ka PTEN hamartoma tumor syndrome (PHTS).

Ke laha nei kēia `(Hamartoma)` i loko o ke kino?

He pilikia nui kēia no nā kānaka he nui. ʻAʻole, ʻaʻole laha ka "Hamartoma" ma ke kino e like me ke kanesa. ʻO ia hoʻi, noho ia ma kahi i hoʻokumu ʻia ai. Eia nō naʻe, i kekahi manawa inā ulu iki kēia puʻupuʻu, hiki iā ia ke paʻi i nā ʻiʻo olakino a i ʻole nā ​​​​​​ʻōpū kokoke a hōʻino i kekahi. Akā, he mea kakaikahi loa ia.

Aia kekahi mau maʻi ʻē aʻe e pili ana me `(Hamartoma)`?

ʻAe, hiki ke pili ʻo Hamartoma me kekahi mau kūlana genetic kakaikahi. I loko o kēia mau kūlana, ua hoʻokumu ʻia ʻo Hamartoma e kahi mutation i loko o kahi gene.

• (Pallister-Hall syndrome - PHS): Pili kēia ʻano me nā mutations i loko o ka gene `GLI3`. Ma kahi o 5% o ka poʻe me `(Hypothalamic hamartomas)` i loko o ka lolo e loaʻa paha kēia ʻano `PHS`.
• ʻO ka sclerosis tuberous: Hiki i kēia kūlana ke hana i ka "Hamartoma" i loko o nā ʻano kino like ʻole e like me ka lolo, ka puʻuwai, nā puʻupaʻa, ka ʻili, a me nā maka.
• ( Neurofibromatosis ʻAno 1 - NF1): He ʻano laha ʻole kēia no ka ʻike hoʻoilina. Ma kēia, hiki i ka "Hamartoma" ke ulu i loko o nā aʻalolo ma ke kino holoʻokoʻa.
• (PTEN hamartoma tumor syndrome - PHTS): He hui kēia o nā maʻi e pili ana i nā mutations i loko o ka gene `PTEN`. ʻO `(Cowden syndrome)` a me `(Bannayan-Riley-Ruvalcaba syndrome - BRRS)` nā ʻano like ʻole o kēia. Hiki i `(Hamartoma)` ke ulu ma nā wahi e like me ka umauma, ka uterus, ka thyroid gland, ka ʻōnaehana gastrointestinal (`GI tract`), a me ka ʻili.
• ʻO ka maʻi Peutz-Jeghers (PJS): Pili kēia me kahi mutation i loko o ka gene STK11/LKB1. ʻOi aku ka nui o ka pilikia o ka poʻe me PJS i ka loaʻa ʻana o nā hamartomas o nā māmā, ka ʻōpū, ka mimi ʻōpū, ka ʻōpū liʻiliʻi, ka colon, a me ka rectum.

Inā loaʻa iā ʻoe kahi maʻi genetic e like me kēia, hiki i kāu kauka ke ʻōlelo i ka hoʻāʻo genetic a i ʻole ke aʻo ʻana.

He aha nā hōʻailona o ka `(Hamartoma)`?

ʻO ka hapa nui o ka manawa, ʻaʻole hōʻike kēia mau `(Hamartomas)` i kekahi mau hōʻailona (`asymptomatic`). ʻO ia hoʻi, hiki iā ʻoe ke loaʻa iā lākou i loko o kou kino me ka ʻole o ka manaʻo ʻoluʻolu ʻole. Eia naʻe, i kekahi manawa, ʻike ʻia nā hōʻailona ke ulu iki kēia puʻupuʻu a kaomi i nā ʻiʻo ma lalo. Inā hana ʻia kēlā, pili nā hōʻailona i kahi o ka `(Hamartoma)`. No ka laʻana, inā nui ka `(Hamartoma)` i loko o nā māmā, hiki iā ʻoe ke ʻike i nā mea e like me ke kuni a me ka paʻakikī o ka hanu ʻana. Inā aia kekahi i loko o ka lolo, e like me ka mea i ʻōlelo ʻia ma mua, hiki ke loaʻa nā hopu a me nā pilikia ʻike.

He aha nā kumu o Hamartoma?

ʻAʻole ʻike nā kānaka ʻepekema i ke kumu kikoʻī o Hamartoma. Eia naʻe, e like me ka mea i ʻōlelo ʻia ma mua, ua pili ia i kekahi mau kūlana genetic. Hoʻoilina pinepine ʻia kēia mau kūlana genetic. ʻO ia hoʻi, hiki ke hana ʻia e kahi mutation genetic i hoʻoilina ʻia mai kekahi o nā mākua.

Hiki iā Hamartoma ke hoʻoulu i nā pilikia?

ʻAʻole koʻikoʻi ka hapa nui o nā hamartomas. Eia nō naʻe, hiki iā lākou ke hana i nā pilikia inā ulu nui lākou e hōʻino i kahi ʻōkana a i ʻole ke ʻano o ke kino. No ka laʻana, hiki i ka rhabdomyoma cardiac i loko o ka puʻuwai ke hana i ka hāʻule ʻana o ka puʻuwai inā hoʻopilikia ia i ka hana o ka puʻuwai. Pēlā nō, hiki i ka hamartoma hypothalamic i loko o ka lolo ke hana i nā hormonal imbalances a me ka hōʻino ʻana o ka noʻonoʻo inā hoʻopilikia ia i ka hana o ka hypothalamus. Akā, mai hopohopo, hiki i kāu kauka ke nānā i ka hamartoma a wehe iā ia inā pono.

Pehea e ʻike ʻia ai ʻo `(Hamartoma)`?

ʻAʻole hōʻike pinepine nā Hamartomas i nā hōʻailona, ​​no laila ua ʻike ʻia lākou i ka wā o ka nānā ʻana no kekahi maʻi ʻē aʻe. I kekahi manawa he mea paʻakikī ke ʻike inā he puʻupuʻu ka hamartoma a ʻaʻole paha, ʻoiai ma muli o kona wahi. E nānā kāu kauka iā ʻoe a nīnau e pili ana i kou mōʻaukala olakino. I ka hapanui o nā hihia, pono nā hoʻokolohua hou aʻe e hōʻoia he hamartoma ia.

He aha nā hoʻokolohua diagnostics?

• X-ray: He hoʻāʻo radiation haʻahaʻa e lawe i nā kiʻi o nā iwi a me nā ʻiʻo palupalu. ʻIke ʻia nā hamartomas i loko o nā māmā e like me ka "popcorn" ma kahi X-ray. Hiki i kēia ke kōkua i ka hoʻokaʻawale ʻana iā lākou mai nā puʻupuʻu kanesa.
• Ultrasound: Hoʻohana i nā nalu kani e kiʻi i nā kiʻi o nā ʻiʻo palupalu i loko o ke kino.
• CT scan (Computed tomography): He scan e hoʻohana ana i nā kukuna X he nui e lawe i nā kiʻi ʻokiʻoki o nā ʻiʻo palupalu a me nā iwi i loko o ke kino. He mea pono loa ka CT scan no ka loaʻa ʻana o nā hamartomas māmā.
• MRI (kiʻi hoʻohālikelike magnetic):Hoʻohana ʻia kahi magnet nui a me nā nalu lekiō e lawe i nā kiʻi kikoʻī o nā ʻiʻo palupalu i loko o ke kino.
• Mammogram: He hoʻāʻo haʻahaʻa e nānā ana i nā ʻiʻo umauma. Loaʻa ka hapa nui o nā hamartomas umauma i ka wā o nā mammograms, i hoʻohana ʻia e nānā no ka maʻi ʻaʻai.
• Biopsy: Ma kēia, lawe ke kauka i kahi ʻāpana liʻiliʻi o ka puʻupuʻu a hoʻouna iā ia i kahi keʻena hoʻokolohua. Ma laila, nānā kahi "Pathologist" i nā ʻāpana ma lalo o kahi microscope. ʻO kēia "Biopsy" wale nō ke ala e ʻike pono ai inā he puʻupuʻu maikaʻi ʻole ia, e like me ka "Hamarthoma", a i ʻole he puʻupuʻu kanesa. ʻO kēia ke ala maopopo loa e ʻike ai i ka maʻi.

Pehea e mālama ʻia ai ʻo Hamartoma?

Hoʻokumu ʻia ka lāʻau lapaʻau i nā kumu e like me kahi o ka hamartoma a inā he mau hōʻailona kāu mai ia mea.

• Inā ʻaʻohe pilikia: Inā ʻaʻole ke kumu o ka puʻupuʻu i kekahi pilikia a i ʻole ke kumu o nā hōʻailona, ​​​​hiki i ke kauka ke hoʻoholo e nānā iā ia me ka ʻole o ka lāʻau lapaʻau. ʻO ke ʻano kēia e nānā pinepine lākou iā ia e ʻike inā e nui ana a e loli ana paha.
• Inā he mau hōʻailona a inā he kānalua paha no ka maʻi kanesa: I ia hihia, ʻo ke ʻoki ʻana e wehe i ka puʻupuʻu ka lāʻau lapaʻau nui.

He aha nā ʻoki kino kikoʻī i hoʻohana ʻia e wehe i kahi hamartoma?

ʻOkoʻa nō hoʻi kēia ma muli o kahi i loaʻa ai ka hamartoma. No ka hamartoma māmā:

• ʻOki ʻoki wedge: Ma kēia, ʻoki ʻia a wehe ʻia kahi ʻāpana liʻiliʻi o ka māmā kahi i loaʻa ai ka puʻupuʻu. Me ka puʻupuʻu, wehe ʻia kekahi mau ʻiʻo olakino a puni ia.
• Lobectomy: Hoʻopau loa ʻia kahi lobe o ka māmā, inā aia ka hamartoma ma kēlā lobe. ʻEkolu lobes o ko mākou māmā ʻākau a ʻelua lobes o ko mākou māmā hema.
• Pneumonectomy: Wehe ʻia ka māmā holoʻokoʻa. Eia nō naʻe, he mea kakaikahi loa ka hamartoma e koi ai i kahi ʻoki nui.

No '(Hypothalamic hamartomas)' i loko o ka lolo:

• ʻO ke ʻoki ʻana: Hoʻopau ke kauka ʻoki a wehe i ka puʻupuʻu.
• Ablation: Ua luku ʻia ka puʻupuʻu me ka hoʻohana ʻana i ka wela kiʻekiʻe a i ʻole ka radiation laser.
• (GammaKnife® radiosurgery): ʻAʻole kēia he ʻoki kino kuʻuna. Hoʻopau ka radiation i ka puʻupuʻu ma ke kuhikuhi ʻana i kahi kukuna ikehu ikaika iā ia. Hoʻopau ia i nā ʻiʻo ʻino me ka pololei, e like me ke ʻoki kino.

He aha ka mea e hana ai inā loaʻa iaʻu kahi `(Hamartoma)`?

ʻAʻole koʻikoʻi ka hapa nui o nā hamartomas, no laila mai hopohopo. Inā pili kahi hamartoma i kahi ʻōkana a i ʻole ua lawa ka nui e hōʻino ai, hiki i ke ʻoki kino ke hoʻoponopono i ka pilikia. I kekahi manawa he paʻakikī ke wehe i kahi hamartoma. No ka laʻana, ulu kekahi mau hamartomas hypothalamic kokoke i ke aʻalolo optic, hiki ke hōʻino ʻia e ke ʻoki kino.

No laila, he mea nui loa e kamaʻilio pono me kāu kauka a ʻike inā pono e wehe ʻia kāu hamartoma, a inā pēlā, he aha nā pilikia a i ʻole nā ​​​​pōʻino e hiki ai ke hana.

Hiki i ka "Hamartoma" ke lilo i maʻi kanesa?

ʻO kēia kekahi makaʻu a ka poʻe he nui. He haʻahaʻa loa ka manawa e lilo ai ka hamartoma i ka maʻi kanesa. ʻO ia hoʻi, ʻaʻole pinepine ia e hana. Akā eia ka mea. Hiki i kekahi mau kūlana genetic e pili ana i ka hamartoma (no ka laʻana, ʻo Cowden syndrome, kahi ʻano o PHTS) ke hoʻonui i ka pilikia o ka loaʻa ʻana o ka maʻi kanesa. I kēlā hihia, ʻaʻole ʻo ka hamartoma ka mea e hoʻonui ai i ka pilikia o ka maʻi kanesa, akā ʻo ke kūlana genetic. No laila, inā loaʻa iā ʻoe kēlā ʻano genetic, he mea nui e nānā mau ʻia no ka maʻi kanesa.

He aha kaʻu e nīnau aku ai i kaʻu kauka?

Ke ʻike ʻoe he "Hamartoma" kou, aia kekahi mau mea āu e nīnau ai i kāu kauka e pili ana i ia mea. Mai makaʻu e nīnau i kēia mau nīnau:

• No ke aha i hoʻomohala ai au i kēia `(Hamartoma)`?
• Pono anei au e wehe i kēia `(Hamartoma)`?
• He aha nā hōʻailona e hōʻike ana he pono kēia i ka mālama ʻia?
• Hiki paha i kēia "Hamartoma" ke lilo i hōʻailona o kekahi maʻi koʻikoʻi ʻē aʻe?
• E pōmaikaʻi anei ke aʻoaʻo ʻana a i ʻole ka hoʻāʻo ʻana i nā hoʻoilina noʻu a i ʻole kekahi o koʻu ʻohana?

ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)

ʻAe, no laila mai kā mākou i kamaʻilio ai, manaʻo wau ua loaʻa iā ʻoe kahi manaʻo maikaʻi e pili ana i ka `(Hamartoma)`. ʻO ka mea nui, ʻaʻole weliweli ʻo `(Hamartoma)` i ka hapa nui o nā hihia. ʻAʻole lākou he maʻi kanesa, a ʻaʻole lākou e laha ma ke kino. I ka hapa nui o ka manawa, ʻaʻole pono lākou e mālama ʻia. Eia nō naʻe, inā he mau hōʻailona, ​​a inā he kānalua ke kauka, hiki ke wehe ʻia ma ke ʻoki ʻana a hiki ke hoʻoponopono ʻia ka pilikia.

Inā haʻi aku ke kauka iā ʻoe he "Hamartoma" kou, mai makaʻu pono ʻole iā ia, e kamaʻilio pono me kāu kauka a hoʻoholo i ka hana maikaʻi loa nou. ʻO ka mālama ʻana i kou olakino ka mea nui loa!

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