Loaʻa iā ʻoe kahi maʻi akepaʻa i kapa ʻia ʻo Primary Biliary Cholangitis ( PBC )? A i ʻole kekahi āu i ʻike ai i loaʻa i kēia maʻi? I ka ʻōlelo maʻalahi, ʻo ia ka wā e hōʻino ʻia ai nā ʻauwai bile i loko o ko kākou akepaʻa a hōʻiliʻili ka bile i loko o ke kino. I kekahi manawa hiki ke lilo kēia i mea ʻole, a i ʻole hiki ke loaʻa nā hōʻailona e like me ka luhi nui a me ka maneʻo . I ka hala ʻana o ka manawa, hiki i kēia maʻi ke lilo i mea koʻikoʻi. No laila i kēia lā ke kamaʻilio nei mākou e pili ana i ka lāʻau lapaʻau hou i kapa ʻia ʻo Iqirvo (elafibranor) e mālama i kēia maʻi.
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He aha ʻo Iqirvo? Pehea e hana ai?
He lāʻau lapaʻau ʻo Iqirvo e kōkua i ka mālama ʻana i ka cholangitis biliary mua (PBC). Hana ia ma ka hoʻēmi ʻana i ka nui o ka bile e hōʻiliʻili ana i loko o kou kino. ʻIke anei ʻoe pehea e hana ai i kēlā? Hōʻailona kēia lāʻau lapaʻau i kou kino e hoʻōki i ka hana ʻana i ka bile. ʻO ia hoʻi, kāohi ia i ka hana ʻana o nā waikawa bile .
ʻO ka maʻamau, hāʻawi ʻia ʻo Iqirvo me kekahi lāʻau ʻē aʻe. ʻO ia lāʻau lapaʻau he ursodeoxycholic acid. Ua hāʻawi paha kāu kauka iā ʻoe i kēia lāʻau.
Pehea i noiʻi ʻia ai kēia lāʻau lapaʻau?
E like me nā lāʻau lapaʻau hou a pau, ua aʻo nui ʻia ʻo Iqirvo ma mua o ka hāʻawi ʻia ʻana i nā kānaka. Ua pili ka noiʻi i 161 mau kānaka me PBC.
- ʻElua hui: Ua māhele ʻia kēia poʻe i ʻelua hui. Ua hāʻawi ʻia kekahi hui i kahi mahele o Iqirvo 80 mg i kēlā me kēia lā. Ua hāʻawi ʻia kekahi hui i kahi pila placebo .
- He aha ka placebo?: He pila hakahaka ia ʻaʻohe lāʻau lapaʻau ikaika a like me ka lāʻau lapaʻau. Hāʻawi ʻia ia e ana i ka hopena maoli o ka lāʻau.
- Manawa: Ua hāʻawi ʻia ka lāʻau lapaʻau ma kēia ʻano no hoʻokahi makahiki ma ka liʻiliʻi. A laila, ua hāʻawi ʻia ka poʻe i makemake e noho i ka noiʻi no kekahi makahiki ʻē aʻe.
Ua nānā nui nā kānaka noiʻi i nā waiwai hoʻokolohua o ke akepaʻa i loko o ke koko e ʻike ai inā e hana ana ka lāʻau. No ka laʻana, ua nānā lākou inā ua hoʻomaikaʻi ʻia nā pae alkaline phosphatase a me bilirubin . Ua ana pū lākou i ke ʻano o ka ʻūlū o nā maʻi me ka hoʻohana ʻana i kahi unahi i kapa ʻia ʻo Worst Itch Numeric Rating Scale (WI-NRS) ma 24 a me 52 mau pule.
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Check Availability →He aha nā hopena o ka noiʻi?
I ka pau ʻana o ka noiʻi, ua ʻike au i kekahi mau mea nui loa.
ʻO ka poʻe i lawe iā Iqirvo, 51% (ʻoi aku ma mua o ka hapalua) i hōʻike i ka hoʻomaikaʻi nui ʻana i nā hopena hoʻāʻo koko e pili ana i ke akepaʻa.
Eia nō naʻe, ʻo 4% wale nō o ka poʻe i lawe i ka placebo i hōʻike i kēia ʻano hoʻomaikaʻi. Hōʻike maopopo kēia he hopena ikaika ko Iqirvo.
E pili ana i ka maneʻo, ʻoiai ua ʻike ka poʻe i lawe iā Iqirvo i kahi hōʻoluʻolu, ua like ia me ka hōʻoluʻolu i ʻike ʻia e ka poʻe i lawe i ka placebo. No laila, he paʻakikī ke ʻōlelo pololei i ka hopena o ka maneʻo.
ʻO ka mea nui loa: E hoʻomanaʻo, he mau hopena noiʻi kēia. Hiki ke ʻokoʻa kāu mau hopena. ʻO ia ke kumu e kūkākūkā ʻia ai nā mea āpau me kāu kauka.
ʻO wai ka mea pono ʻole e lawe iā Iqirvo?
ʻAʻole kūpono kēia lāʻau lapaʻau no nā kānaka a pau. Inā loaʻa iā ʻoe kekahi o kēia mau maʻi, ʻaʻole pono ʻoe e lawe iā Iqirvo. E kamaʻilio me kāu kauka e pili ana i kēia.
| Kūlana | Wehewehena |
|---|---|
| Maʻi akepaʻa koʻikoʻi | Inā loaʻa iā ʻoe ka maʻi ate koʻikoʻi, ʻoi aku hoʻi ka cirrhosis decompensated. |
| Ka pale ʻana o ka ʻōpū gall | Inā he ālai ʻia kou biliary i loko o kou ake. |
| Hāpai keiki | Inā hāpai ʻoe a i ʻole ke manaʻolana nei e hāpai. |
| Ka hānai ʻana i ka waiū umauma | Inā he makuahine ʻoe e hānai waiū ana i kāu keiki. |
Nā hopena ʻaoʻao a pehea e mālama ai iā lākou?
E like me nā lāʻau lapaʻau āpau, hiki iā Iqirvo ke hana i nā hopena ʻaoʻao i kekahi poʻe.Hiki ke loaʻa nā hopena ʻaoʻao .
Nā haki iwi
ʻOiai he mea maʻamau ʻole kēia, i nā noiʻi, ua loaʻa i kekahi poʻe i lawe iā Iqirvo nā haki iwi. E haʻi i kāu kauka inā ua loaʻa iā ʻoe kahi haki iwi ma mua a inā paha ʻoe e pilikia ana i ka haki iwi (e like me ka osteoporosis ). Hiki i kēia mau mea ke kōkua i ka mālama ʻana i kou mau iwi i ikaika:
- E ʻai i nā meaʻai waiwai i ka calcium: nā mea e like me ka yogurt, tofu, ka iʻa sālemona. Inā pono, e lawe i nā papa calcium e like me ke kuhikuhi a kāu kauka.
- E kiʻi i ka Vitamin D : Loaʻa ka Vitamin D mai nā meaʻai e like me ka iʻa ʻaila, nā hua manu , a me ka lā.
- E hoʻoikaika kino pinepine: Hoʻoikaika kēia i nā ʻiʻo a hōʻemi i ka pilikia o ka hāʻule ʻana.
- E pale i ka puhipaka.
- E kāohi i ke kō a me ka waiʻona.
Nā hopena ʻaoʻao maʻamau ʻē aʻe
Aia ma lalo iho kekahi o nā hopena ʻaoʻao a ka hapa nui o ka poʻe e ʻike ai a me nā mea maʻalahi hiki iā ʻoe ke hana e pili ana iā lākou. Akā inā hoʻomau kēia mau mea , e ʻike pono i kāu kauka .
| Ka hopena ʻaoʻao | Nā mea hiki iā ʻoe ke hana |
|---|---|
| Ka luaʻi a me ka luaʻi | E inu i nā wai e like me ka ginger ale a i ʻole ka wai. Hiki i nā meaʻai palupalu e like me nā crackers a me ka toast ke kōkua. |
| Ka paʻa ʻana o ka ʻōpū | E inu i ka wai he nui. E ʻai i nā huaʻai, nā mea kanu, a me ka fiber. He maikaʻi nā probiotics e like me ka yogurt a me kefir. |
| ʻĀʻī puʻuwai | E pale i nā mea e hoʻonui ai i ka mumū, e like me ke kokoleka, nā meaʻai momona, ke kofe, a me ka waiʻona. E ʻai i nā meaʻai liʻiliʻi ma mua o ka ʻai nui ʻana i ka manawa hoʻokahi. Hiki iā ʻoe ke nīnau i kāu kauka e pili ana i ka lawe ʻana i nā antacids. |
| Waha maloʻo | E nau i ka gum a i ʻole ka mea ʻono me ke kō ʻole. E inu i ka wai he nui. E ho'āʻo e hanu ma kou ihu ma kahi o kou waha. |
Hiki iā Iqirvo ke launa pū me nā lāʻau lapaʻau ʻē aʻe? (Nā Hana Pilikino Lāʻau Lapaʻau)
ʻAe, he mea nui loa kēia. Hiki iā Iqirvo ke launa pū me kekahi mau lāʻau lapaʻau ʻē aʻe āu e lawe nei. Hiki paha i kēia ke hōʻemi i ka pono o ka lāʻau lapaʻau a hoʻonui paha i nā hopena ʻaoʻao.
| ʻAno lāʻau lapaʻau | Nā hopena a me nā ʻōlelo aʻoaʻo |
|---|---|
| Nā lāʻau/ʻano hana hoʻomalu hānau | ʻO ka lawe ʻana iā Iqirvo e hōʻemi paha i ka pono o nā ʻano kaohi hānau hormonal (nā pila, nā ʻāpana). No laila, he mea nui e hoʻohana i kekahi ʻano kaohi hānau ʻē aʻe, e like me nā condom. |
| ʻO Statins, kahi ʻano lāʻau hoʻohaʻahaʻa cholesterol | ʻO ka lawe pū ʻana i kēia mau lāʻau lapaʻau ʻelua e hoʻonui paha i ka pilikia o ka ʻeha a i ʻole ka hōʻino ʻana o nā ʻiʻo. Inā loaʻa iā ʻoe kēlā ʻeha, e haʻi koke i kāu kauka. |
| Nā mea hoʻopaʻa waikawa bile | He mau lāʻau lapaʻau kēia no ka cholesterol. Hiki i kēia ke pale i ke kino mai ka omo ʻana iā Iqirvo. No laila, pono e lawe ʻia kēia lāʻau lapaʻau i 4 mau hola ma mua a ma hope paha o ka lawe ʻana iā Iqirvo. |
| ʻO Rifampin | He lāʻau antibiotic kēia i hoʻohana ʻia no ka mālama ʻana i ka maʻi puʻupuʻu. Hiki iā ia ke hōʻemi i ka nui o Iqirvo i loko o kou kino. Inā ʻoe e lawe ana i kēia mau lāʻau ʻelua, e hana kāu kauka i nā hoʻokolohua koko. |
No laila, he mea nui loa e haʻi aku i kāu kauka e pili ana i kēlā me kēia lāʻau lapaʻau āu e lawe ai, ʻoiai he huaora a i ʻole ka lāʻau Ayurvedic.
Leka Lawe-Home
- He lāʻau lapaʻau hou ʻo Iqirvo i hoʻohana ʻia e mālama ai i ka cholangitis biliary mua (PBC).
- Hana nui kēia ma ka hoʻemi ʻana i ka hana bile a ke kino a me ka kaohi ʻana i ka hōʻino ʻia o ke ake.
- Ua hōʻike ʻia e ka noiʻi he mea maikaʻi loa kēia i ka hoʻomaikaʻi ʻana i nā hopena hoʻāʻo koko e pili ana i ke akepaʻa.
- ʻAʻole kūpono kēia no nā wahine hāpai, nā wahine hānai waiū, a me nā poʻe me nā maʻi kanesa koʻikoʻi.
- He mea nui e hoʻomaopopo i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei, no ka mea, hiki i kekahi mau lāʻau lapaʻau ke launa pū me Iqirvo.
- E kamaʻilio ākea me kāu kauka e pili ana i nā hopena ʻaoʻao a i ʻole nā hopohopo.
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