He aha ka Mantle Cell Lymphoma? E kamaʻilio kākou e pili ana i ia mea!

ʻAʻole paha ʻoe e ʻike i kekahi manawa aia nā kaua leo ʻole e hana nei i loko o ko kākou kino. No ka laʻana, ʻo Mantle Cell Lymphoma (MCL) kahi maʻi kanesa laha ʻole e hoʻomaka ana i loko o kā kākou mau keʻokeʻo koko i kapa ʻia ʻo lymphocytes. He ʻano lymphoma maoli ia i kapa ʻia ʻo non-Hodgkin lymphoma. E kamaʻilio maʻalahi kākou e pili ana i kēia, ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.

Pehea e ulu ai ka lymphoma cell mantle (MCL)? He aha ka mea e hana ʻia i ke kino?

E noʻonoʻo, hoʻomaka kēia maʻi kanesa i kapa ʻia ʻo MCL e laha mālie a malū i loko o ke kino i ka wā mua. Akā ma hope o kekahi manawa, hiki ke ulu koke. Hoʻolaha nui kēia ma o kā mākou ʻōnaehana lymphatic. ʻO ka ʻōnaehana lymphatic kahi ʻano wai i loko o ko mākou kino a me kahi pūnaewele o nā kīʻaha koko e lawe ana i kēlā wai. Ua like ia me kahi ʻōnaehana e wehe ana i nā ʻōpala mai ko mākou kino. Ke ʻoi aku ka ʻino o ka maʻi , hiki i kēia mau hunaola kanesa ke puka i waho o nā lymph nodes a laha i ko mākou kahe koko, ka iwi iwi, a i kekahi manawa i nā wahi e like me ka ʻōnaehana digestive.

ʻO ka mea nui, hiki i ke kanaka me MCL ke loaʻa nā manawa o ka hoʻomaha ʻana, a hiki nō hoʻi iā lākou ke loaʻa hou. Hiki ke hana i kēia i nā manawa he nui. ʻOiai ʻaʻole hiki i ka lāʻau lapaʻau ke ho'ōla loa i ka MCL, hiki iā ia ke kōkua i ka hoʻolōʻihi ʻana i ka manawa o ka hoʻomaha ʻana.

He maʻi kanesa laha ʻole ka Mantle cell lymphoma. Hoʻopilikia ia i hoʻokahi i loko o 200,000 mau kānaka. ʻOiai hiki i kekahi ke loaʻa i kēia maʻi kanesa, ʻoi aku ka nui o ka pilikia o ka poʻe ma waena o 60 a me 70 mau makahiki.

He aha nā ʻano o ka lymphoma cell mantle (MCL)?

ʻElua ʻano nui o ka MCL: 1. Classical MCL: ʻO kēia ke ʻano maʻamau. Hoʻomaka ia ma nā lymph nodes a laha i nā ʻāpana ʻē aʻe o ke kino. ʻOi aku ka ikaika o ke ʻano maʻamau. 2. Leukaemic non-nodal MCL: Hoʻopili pinepine kēia ʻano i ka spleen i hoʻonui ʻia a me nā cell lymphoma i loko o ke koko a me ka iwi iwi. Ulu mālie ia ma mua o ke ʻano classical.

He aha nā hōʻailona o kēia maʻi? Pehea ʻoe e ʻike ai?

Hiki ke ʻokoʻa nā hōʻailona MCL mai kēlā kanaka a kēia kanaka. I kekahi manawa hiki iā lākou ke like me nā hōʻailona o kahi maʻi maʻamau, no laila ʻaʻole paha ʻoe e manaʻo he maʻi kanesa ia. ʻO ia ke kumu e ʻike pinepine ʻia ai ka MCL i ka wā lohi, i ka wā i pālahalaha mua ai ka maʻi. ʻAʻohe paha ou hōʻailona iki. Eia naʻe, inā loaʻa iā ʻoe nā hōʻailona, ​​hiki iā lākou ke komo pū me:

• ʻEha
• ʻEha poʻo
• Luhi mau ka manaʻo ( fatigue )
• kuni
• Nā ʻeha o ka ʻōpū
• Makemake nui
• No ka pōKa hou ʻana
• Nā ʻōpū lymph pehu (e like me ka ʻāʻī, nā armpits, ka ʻūhā)
• Manaʻo o ka nāwaliwali
• ʻO ka pohō kaumaha me ke kumu ʻole

Mai makaʻu i ka MCL no ka mea wale nō he mau hōʻailona kēia iā ʻoe. Akā inā hoʻomau kēia mau hōʻailona, ​​ʻoi aku ka maikaʻi o ke ʻike ʻana i ke kauka .

He aha ke kumu o ka lymphoma cell mantle (MCL)?

ʻO ka hapa nui o ka manawa, hoʻokumu ʻia ʻo MCL e kahi mutation i loko o kekahi o kā mākou mau genes. Hoʻololi kēia mutation i ke ʻano o ka hana a kā mākou mau cell B, kahi ʻano lymphocyte. ʻAʻole maopopo i nā mea noiʻi ke kumu o kēia mutation. Akā eia ka mea e hana ʻia: 1. Hoʻopuka nā cell B i hoʻololi ʻia i ka nui o ka protein i kapa ʻia ʻo cyclin D1. Kōkua kēia protein i nā cell B e ulu. 2. ʻO ka hana nui ʻana o kēia protein cyclin D1 ke kumu o ka māhele ʻana a me ka hoʻonui ʻana o nā cell B me ke kāohi ʻole. 3. Hoʻopili pū nā cell e māhele ana me ke kāohi ʻole e hana i nā tumors.

He aha nā pilikia o kēia maʻi?

I ka holomua ʻana o ka lymphoma cell mantle, hiki mai nā pilikia e like me:

• Ke kahe koko ʻana o ka ʻōpū
• ʻO ka spleen i haki
• ʻO ka maʻi lysis tumor (kahi pilikia i hoʻokumu ʻia e ka wikiwiki o ka haki ʻana o nā hunaola kanesa)

Pehea e ʻike ʻia ai ka lymphoma cell mantle (MCL)?

Inā kānalua kāu kauka he MCL kou, e hana paha lākou i kekahi mau hoʻokolohua.

• Nā hoʻāʻo lab: Hiki i kēia ke komo pū me ka helu koko piha (CBC), kahi panel metabolic piha (CMP), kahi hoʻāʻo LDH, a i ʻole kahi hoʻāʻo pae uric acid. Hoʻopūhoihoi pinepine nā kauka inā ʻike lākou i ka piʻi ʻana o ka helu o nā lymphocytes i loko o kahi hoʻāʻo koko.
• Nā Biopsies: Hiki i kāu kauka ke ʻōlelo aku i kahi biopsy node lymph a i ʻole kahi biopsy iwi iwi e hōʻoia inā loaʻa nā hunaola kanesa. Nānā ʻia ka hāpana ʻiʻo e kahi pathologist.
• Nā hoʻāʻo kiʻi: Kōkua kēia mau hoʻāʻo e ʻike i ka mamao o ka laha ʻana o ke kanesa. Ma muli o kahi o ke kanesa, pono paha ʻoe e hana i kahi colonoscopy, CT scan, EGD (esophagogastroduodenoscopy), a i ʻole PET scan.

Inā ʻaʻole kūpono nā hopena o ka hoʻāʻo koko, e nānā kāu kauka iā ʻoe a nīnau e pili ana i kāu mau hōʻailona. Hiki paha iā lākou ke hoʻopā i nā wahi e like me kou ʻāʻī a me nā armpits e ʻike inā ua pehu kou mau lymph nodes.

He aha nā pae o ka lymphoma cell mantle (MCL)?

Hoʻokaʻawale nā ​​kauka i ka maʻi i nā pae ma muli o ka mamao o kona laha ʻana. Hoʻohana lākou i kahi ʻōnaehana kūikawā i kapa ʻia ʻo Mantle Cell Lymphoma International Prognostic Index (MIPI). Hāʻawi kēia i kahi manaʻo maʻamau o ka lōʻihi o ke ola o ka mea maʻi. Ma keʻano laulā, ʻoi aku ka nui o ka maʻi e hoʻi hou i nā pae ma hope ma mua o nā pae mua. Hoʻoholo ʻia ke kahua e ka mamao o ka laha ʻana o ke kanesa:

• Pae I: Palena ʻia i hoʻokahi a i ʻole kekahi mau lymph nodes ma ka wahi like.
• Pae II: Ua pālahalaha ia i ʻelua a ʻoi aku paha nā lymph nodes ma ka ʻaoʻao like o kou diaphragm.
• Pae III: Ua pālahalaha ia i nā ʻaoʻao ʻelua o ka diaphragm, a i ʻole i ka spleen a me nā lymph nodes ma luna o ka diaphragm.
• Pae IV: Ua pālahalaha ka lymphoma cell Mantle i nā wahi mamao loa o ke kino, a i ʻole i nā wahi ʻē aʻe ma mua o nā lymph nodes.

Pehea e mālama ʻia ai ka lymphoma cell mantle (MCL)?

ʻAʻole like ka lāʻau lapaʻau no MCL no kēlā me kēia kanaka. ʻO ka lāʻau lapaʻau kūpono iā ʻoe e pili ana i nā mea e like me kahi o ke kanesa a me ka wikiwiki o kona ulu ʻana. Eia kekahi o nā lāʻau lapaʻau i loaʻa no MCL:

• Chemotherapy: Nā lāʻau lapaʻau i hāʻawi ʻia e luku i nā hunaola kanesa.
• Immunotherapy: He lāʻau lapaʻau e hoʻoulu ai i ka ʻōnaehana pale ponoʻī o kou kino e hakakā i ka maʻi kanesa.
• Lapaʻau radiation: Ke luku ʻana i nā hunaola kanesa me ka hoʻohana ʻana i nā kukuna ikehu kiʻekiʻe.
• Lapaʻau i hoʻolālā ʻia: Nā lāʻau lapaʻau e hoʻolālā ana i nā molekala kikoʻī e kōkua ana i nā pūpū kanesa e ulu a hoʻolaha.
• Hoʻoili pūnaewele kumu: Ke hoʻoili ʻana o nā pūnaewele kumu olakino e pani i ka iwi iwi maʻi.

Hiki paha iā ʻoe ke kūpono no kekahi o kēia mau lāʻau lapaʻau, a ʻaʻole paha ʻoe e kūpono no kekahi.

Inā loaʻa iā ʻoe ka MCL, he manaʻo maikaʻi nō hoʻi e noʻonoʻo i nā hoʻokolohua lapaʻau e hoʻāʻo ana i nā lāʻau lapaʻau hou. ʻAʻole paha e ho'ōla loa kēia mau lāʻau lapaʻau hou i ka MCL, akā hiki iā lākou ke hāʻawi iā ʻoe i ka manawa hou aʻe e ola ai i kahi ola hauʻoli a ʻaʻohe hōʻailona. E nīnau i kāu kauka e pili ana i kēia.

Hiki ke pale ʻia ka lymphoma cell mantle (MCL)?

ʻO ka mea pōʻino, ʻaʻole hiki ke pale ʻia ʻo MCL. ʻOiai ua loaʻa iā ʻoe kēia maʻi, ʻaʻole ia he manaʻo ua hana hewa ʻoe. Ke hoʻāʻo nei nā kānaka noiʻi e ʻike i ke kumu e loli ai nā genes i loko o ko mākou kino (mutate) ma nā ʻano e hoʻoulu ai i nā maʻi kanesa e like me MCL.

Pehea ke ʻano o ke ola me ka mantle cell lymphoma (MCL)?

ʻAʻole hiki ke ho'ōla piha ʻia ka lymphoma cell Mantle. Eia nō naʻe, aia nā lāʻau lapaʻau e hiki ke kōkua iā ʻoe e hoʻi i ke kala ʻana. ʻO ka hoʻomaha ʻana, ʻaʻole ia he manaʻo ua ho'ōla loa ʻia ke kanesa. Hiki i ka MCL ke hoʻi hou i nā mahina a i ʻole nā ​​makahiki ma hope. ʻOi aku ka pōkole o ka manawa āu e noho ai i ke kala ʻana me MCL. Eia nō naʻe, ua hōʻike ʻia nā lāʻau lapaʻau hou i kuhikuhi ʻia e hoʻonui i kēia manawa. E kamaʻilio me kāu kauka e aʻo hou e pili ana i kāu prognosis.

Ka helu ola

ʻO ka nui o ke ola ʻana no ʻelima makahiki no ka lymphoma mantle cell ma kahi o 50%. ʻO ke ʻano kēia, ma kahi o ka hapalua o ka poʻe i ʻike ʻia me kēia maʻi e ola mau ana i ʻelima mau makahiki ma hope o ka ʻike ʻia ʻana.

Akā e hoʻomanaʻo, he mau kuhi wale nō kēia mau helu ola. ʻAʻole lākou e haʻi pololei iā ʻoe i ka lōʻihi o kou ola ʻana a i ʻole pehea ʻoe e pane ai i kekahi lāʻau lapaʻau. ʻOi aku ka maikaʻi o ke kamaʻilio ʻana me kāu kauka e ʻike pehea e pili ai kēia mau helu iā ʻoe.

Pehea ʻoe e mālama ai iā ʻoe iho?

He mea nui loa ka mālama ʻana iā ʻoe iho i ke kino, ka noʻonoʻo, a me ka naʻau i ka wā e noho ana me ka lymphoma mantle cell. Eia kekahi mau manaʻo e hiki ke kōkua iā ʻoe:

• E ʻae i kou mau manaʻo: ʻO ka kāohi ʻana i nā manaʻo e like me ke kaumaha a me ka makaʻu ʻaʻole ia e hoʻopau iā lākou. ʻO ka hoʻomaopopo ʻana a me ka ʻae ʻana i kou mau manaʻo e hōʻike ʻia ke kaʻina mua i ka loaʻa ʻana o ke kākoʻo āu e pono ai.
• E kiʻi i ke kākoʻo: He mea kōkua ke hui pū me kahi hui kākoʻo me nā poʻe e hele nei i nā ʻike like. E nīnau i kāu kauka e pili ana i nā hui ma kou wahi a i ʻole ma ka pūnaewele.
• E hoʻokele i ke kaumaha: E ʻimi i nā ala e hoʻomaha ai. E hoʻāʻo i nā hoʻomaʻamaʻa noʻonoʻo pono, e like me ka noʻonoʻo ʻana.
• E komo i kahi hana maʻamau: ʻO ke kaʻina hana hoʻomaha a me ka hoʻi hou ʻana o ka maʻi hiki ke hoʻolilo i nā mea āpau i mea haunaele. ʻO ka hoʻokumu ʻana i kahi hana maʻamau no kāu mau hana o kēlā me kēia lā a me ka pili ʻana iā ia hiki ke kōkua iā ʻoe e loaʻa kahi kaohi.
• E kamaʻilio me ke kākāʻōlelo: He mea nui e mālama i kou olakino noʻonoʻo. Hiki i ke kākāʻōlelo a mea hoʻoponopono paha ke kōkua iā ʻoe e hoʻoponopono i nā manaʻo paʻakikī.

Āhea ʻoe e ʻike ai i ke kauka?

Inā ʻoe e mālama ʻia ana no ka lymphoma cell mantle, pono ʻoe e ʻike pinepine i kāu kauka. E nānā lākou i kou kūlana a kōkua iā ʻoe e hoʻokele i nā hopena ʻaoʻao o kāu lāʻau. Inā e hoʻomaha ana kāu maʻi, pono ʻoe e ʻike i kāu kauka i kēlā me kēia manawa (nā hahai ʻana). E nīnau i kāu kauka i ka pinepine o kāu loaʻa ʻana o kēia mau manawa. Inā loaʻa iā ʻoe ka lymphoma cell mantle (MCL), ke noho nei ʻoe me ka maopopo ʻole o kahi maʻi e nalowale maoli ʻole. Hopohopo pinepine paha ʻoe inā e hoʻi hou ka maʻi. A i ʻole e noʻonoʻo paha ʻoe inā kūpono ka lāʻau iā ʻoe. He mea maʻamau ka manaʻo i kēia mau manaʻo. Akā inā ke pale nei kēia hopohopo iā ʻoe mai ka hauʻoli ʻana i ke ola, e kamaʻilio me kāu kauka . Hiki iā lākou ke kuhikuhi iā ʻoe i nā kumuwaiwai e hiki ke kōkua iā ʻoe ma kāu huakaʻi.

ʻO ka mea hope loa, leka lawe i ka home:

Hiki i ka Mantle cell lymphoma (MCL) ke lilo i huaʻōlelo weliweli. Eia nō naʻe, he mea nui e makaʻala iā ia, e hoʻolohe i nā hōʻailona, ​​a e ʻimi i ke aʻo lapaʻau i ka manawa kūpono. E hoʻomanaʻo, ʻaʻole ʻoe hoʻokahi. Me ka lāʻau lapaʻau kūpono a me ke kākoʻo, e loaʻa iā ʻoe ka ikaika e kū ai i kēia kūlana. Mai kānalua e kaʻana like i kāu mau nīnau a hopohopo paha me kāu kauka. Mantle Cell Lymphoma, Kanesa, Kanesa Koko, ʻŌnaehana Lymphatic, Nā Hōʻailona, ​​Lapaʻau