Ke manaʻo nei ʻoe i kekahi manawa i ka luhi a me ka palaualelo me ke kumu ʻole? Ke nalowale nei anei kou makemake i ka ʻai , ka emi ʻana o ke kaumaha , a i ʻole ka poniuniu ? Ua ʻike paha ʻoe ua lilo iki kou ʻili, ʻoiai kou mau kuʻekuʻe lima a me kou mau kuli , i ʻeleʻele. Mai hoʻowahāwahā wale i kēia mau mea. He hōʻailona paha lākou no kekahi mea nui e hana nei i loko o kou kino. I kēia lā, ke kamaʻilio nei mākou e pili ana i kekahi ʻano maʻi, ʻo ia hoʻi ka maʻi ʻo Addison .
I ka ʻōlelo maʻalahi, he aha ka maʻi ʻo Addison?
E noʻonoʻo i ko kākou kino me he hui nui lā. Loaʻa i kēia hui kahi hui o nā " ʻelele kemika" e hoʻololi i nā leka e mālama i nā hana like ʻole e holo pono ana. Kāhea mākou i kēia mau hormones .
Ma luna o ko kākou mau puʻupaʻa, e like me ʻelua mau pāpale liʻiliʻi, aia ʻelua mau kelepa liʻiliʻi. ʻO kēia nā mea a kākou e kapa nei he mau kelepa adrenal . Hoʻopuka kēia mau kelepa i ʻelua o nā hormones koʻikoʻi loa e pono ai ko kākou ola. ʻO lākou ka cortisol a me ka aldosterone .
ʻO ka maʻi ʻo Addison kahi maʻi i hōʻino ʻia ai nā kelepa adrenal no kekahi kumu a ʻaʻole hiki ke hana i ka nui e pono ai o kēia mau hormones. He maʻi kakaikahi loa kēia. Akā he mea nui loa ka makaʻala i kēia.
He aha ka hana a nā hormones ʻelua?
- Cortisol: Ua like kēia me ka "luna hoʻokele koʻikoʻi" o ko mākou kino. Hoʻomākaukau kēia hormone i ke kino e kū i ka maʻi, ka pōʻino, a me ke kaumaha. Kōkua pū ia i ka hoʻomalu ʻana i ke koko, nā pae kō koko, a me ka hoʻohana ʻana i ka protein, nā kalapona, a me ka momona.
- ʻAldosterone: ʻO kēia hormone ka "mea hoʻoponopono paʻakai a me ka wai" o ko mākou kino. Kōkua ia i ko mākou mau puʻupaʻa e mālama i ke kaulike o ka paʻakai (sodium) a me ka potassium i loko o ke kino. Hoʻomalu pū ia i ko mākou koko.
Ke haʻahaʻa kēia mau hormones, ua hoʻopilikia ʻia nā hana o ke kino holoʻokoʻa. ʻO ia ka mea e hana ʻia ana ma ka maʻi ʻo Addison.
He aha nā hōʻailona o ka maʻi ʻo Addison?
Hōʻike mālie mai nā hōʻailona o ka maʻi ʻo Addison. No laila, i kekahi manawa hiki ke lōʻihi ka manawa e ʻike ai he maʻi ia. Ua like kēia mau hōʻailona me nā maʻi maʻamau ʻē aʻe, no laila hiki ke kuhihewa ʻia.
E nānā i ka papa ma lalo no nā hiʻohiʻona nui āu e ʻike ai.
| Hōʻailona | Wehewehena |
|---|---|
| Luhi mau a me ka nāwaliwali o nā ʻiʻo | Luhi a make ke ola i ka lā a pau, me ka nānā ʻole i ka nui o ka hoʻomaha āu e loaʻa ai. |
| ʻEleʻele/ʻeleʻele o ka ʻili (Hyperpigmentation) | ʻEleʻele ka ʻili ma nā wahi e like me nā kuʻekuʻe lima, nā kuli, nā puʻupuʻu lima, nā lehelehe, a me nā ʻāʻī. Hiki i nā ʻeha kahiko ke lilo i ʻeleʻele. |
| Ka nalowale o ka makemake a me ka pohō kaumaha | Ka nalowale o ka makemake a me ka pohō kaumaha ma muli. |
| Ke koko haʻahaʻa (Hypotension) | Inā manaʻo ʻoe ua poniuniu ʻoe, ʻoiai ke kū ʻoe mai kahi noho ʻana, hiki ke kumu o ke koko haʻahaʻa. Hiki paha iā ʻoe ke nalowale ka ʻike. |
| Makemake nui i ka paʻakai | I ka emi ʻana o ka paʻakai i loko o ke kino, aia ka makemake mau e ʻai i nā meaʻai paʻakai a me nā mea e like me ka pickles. |
| Nā hiʻohiʻona ʻē aʻe | Ka luaʻi, ka ʻeha o ka ʻōpū, ka pehu ʻana, ke kō koko haʻahaʻa (hypoglycemia), ka hoʻomaha ʻole o ka noʻonoʻo, a me nā pōʻaiapuni menstrual kūpono ʻole i nā wahine. |
He aha nā kumu o ka maʻi ʻo Addison?
ʻO ke kumu nui o ka maʻi ʻo Addison he maʻi autoimmune.I ka ʻōlelo maʻalahi, ʻo ia ka manawa e hele hewa ai ka ʻōnaehana pale o ko mākou kino a hoʻouka a luku i kā mākou mau kelepa adrenal ponoʻī. ʻO kēia ke kumu o 70% o nā maʻi o Addison.
Eia kekahi, aia paha nā kumu ʻē aʻe.
- Nā maʻi: ʻO nā maʻi lōʻihi e like me ka maʻi puʻupuʻu a me ka HIV hiki ke hōʻino i nā kelepa adrenal.
- Kanesa: Hoʻolaha nā hunaola kanesa i hana ʻia ma kahi ʻē aʻe i nā kelepa adrenal.
- Ke kahe koko kūloko: Ke kahe koko ʻana i loko o nā kelepa adrenal.
- Nā kumu hoʻoilina: Aia kekahi pilikia o ka hoʻomohala ʻana i kēia maʻi ma muli o kekahi mau kūlana hoʻoilina.
- ʻOki kino: Inā ua hana ʻia ʻoe i ke ʻoki kino e wehe i nā kelepa adrenal.
Pehea ʻoe e ʻike ai i kēia, e Kauka?
Inā loaʻa iā ʻoe kekahi o kēia mau hōʻailona, e ʻike koke i kāu kauka ʻohana . E nānā ʻo ia iā ʻoe a kuhikuhi iā ʻoe i kahi loea inā pono.
Hoʻohana nui ʻia kekahi mau hoʻāʻo koko e ʻike ai i ka maʻi.
1. Hoʻāʻo koko maʻamau: E nānā kēia inā haʻahaʻa kou pae sodium (paʻakai) koko a inā kiʻekiʻe kou pae potassium.
2. Hoʻāʻo Hoʻoulu ACTH: ʻO kēia ka hoʻāʻo koʻikoʻi loa. Ma kēia, hāʻawi ʻia kahi liʻiliʻi o ka hormone i kapa ʻia ʻo ACTH, ka mea i hoʻokuʻu ʻia e kou lolo, ma ke ʻano he inikini. I ke kanaka olakino, hoʻoulu kēia inikini i nā kelepa adrenal e hana i ka nui o ka hormone cortisol. Eia nō naʻe, i ke kanaka me ka maʻi ʻo Addison, ʻaʻole pane nā kelepa ma kēia ʻano. Ua hōʻoia ʻia ka maʻi ma ka lawe ʻana i kahi hāpana koko a me ke ana ʻana i kēia pae cortisol.
Eia kekahi, hiki ke hana ʻia kahi CT scan e nānā i ka maʻi, ke kanesa, a i ʻole ke kahe ʻana o ke koko i loko o nā kelepa adrenal.
ʻO ka mea weliweli loa: ʻO ka pilikia Addisonian
ʻO kēia ke kahua weliweli loa a koke loa o ka maʻi ʻo Addison. Hōʻike mālie pinepine nā hōʻailona, no laila ʻaʻole ʻike kekahi poʻe ua loaʻa iā lākou ka maʻi. I kēia manawa, inā pilikia nui ke kino, e like me kekahi maʻi ʻē aʻe, ʻoki kino, a i ʻole kahi ulia, hiki i nā hōʻailona ke lilo koke i mea koʻikoʻi loa. Ua kapa ʻia kēia he pilikia Addisonian .
He pilikia olakino kēia a hiki ke alakaʻi i ka make inā ʻaʻole mālama ʻia.
Nā hōʻailona o ka pilikia Addisonian:
- ʻEha koke a nui ma ke kua, ka ʻōpū, a i ʻole nā wāwae.
- ʻO ka luaʻi nui a me ka maʻi pākī, e hopena ana i ka dehydration.
- Ka haʻalulu i hoʻokumu ʻia e ke koko haʻahaʻa loa.
- Ka nalowale o ka ʻike.
- Ka wela koke a me ka nāwaliwali nui.
Inā ʻike ʻia kēia mau hōʻailona,Pono e lawe koke ʻia ka mea maʻi i ka Emergency Treatment Unit (ETU) o ka haukapila kokoke loa.
Ka mālama ʻana a me ke ola maʻamau
E makaʻu paha ʻoe i ka lohe ʻana e pili ana i ka maʻi ʻo Addison, akā ʻo ka nūhou maikaʻi, aia nā lāʻau lapaʻau kūpono loa no ia.
Hoʻokumu ʻia kēia maʻi e ʻelua ʻano hormones i nele i ke kino. No laila, ʻo ka lāʻau lapaʻau, ʻo ia ka hāʻawi ʻana i kēlā mau hormones ma waho ma ke ʻano o nā pila.
- ʻO Hydrocortisone: He lāʻau steroid e pani ai i ka hormone cortisol.
- Fludrocortisone: He pila e pani ai i ka hormone aldosterone.
Pono e lawe ʻia kēia lāʻau i kēlā me kēia lā, e like me ke kauoha a ke kauka.
ʻO ka mea nui loa, ʻaʻole loa e hōʻalo i hoʻokahi mahele lāʻau. ʻOiai ka hala ʻana o hoʻokahi mahele lāʻau, hiki ke lilo i mea weliweli.
Inā loaʻa iā ʻoe kahi maʻi, he kuni, a i ʻole ke hana ʻia nei ke ʻoki kino, e hoʻonui kāu kauka i ka nui o kēia lāʻau lapaʻau no kekahi manawa e pale aku ai i kahi pilikia Addisonian.
Me ka mālama kūpono , hiki i kekahi me ka maʻi ʻo Addison ke ola i kahi ola maʻamau a olakino maikaʻi loa .
Leka Lawe-Home
- ʻO ka maʻi ʻo Addison kahi maʻi i hiki ʻole ai i nā kelepa adrenal ke hana i ka lawa o nā hormones cortisol a me aldosterone.
- ʻO nā hōʻailona nui ka luhi mau, ka pohō kaumaha, ke koko haʻahaʻa, a me ka ʻeleʻele o ka ʻili.
- Inā loaʻa iā ʻoe kēia mau hōʻailona, mai hopohopo a e ʻike koke i ke kauka .
- ʻOiai he maʻi kēia no ke ola holoʻokoʻa, hiki iā ʻoe ke ola i kahi ola maʻamau ma ka lawe ʻana i ka lāʻau lapaʻau i kēlā me kēia lā.
- Inā loaʻa iā ʻoe ka maʻi ʻo Addison, e kau mau i kahi kāleka a kūpeʻe lima paha e hōʻike ana i kou kūlana. Hiki iā ia ke lilo i mea hoʻopakele i ka wā pilikia.
- He pilikia ko Addisonian e pono ai ka mālama koke ʻana. He mea nui e ʻike i nā hōʻailona.
ʻO ka maʻi ʻo Addison, nā hormones, nā kelepa adrenal, cortisol, aldosterone, luhi mau, ʻeleʻele o ka ʻili, nā kelepa adrenal, ka lawa ʻole o ka adrenal, ke koko haʻahaʻa
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