Koj puas ib txwm nkees? Qhov no puas yog teeb meem nrog koj lub qog pituitary? (Hypopituitarism)

Puas muaj tej lub sij hawm koj xav tias koj lub cev tsis muaj zog, zoo li muaj ib yam dab tsi ploj lawm? Tej zaum qhov laj thawj rau qhov no yog ib qho teeb meem me me hauv ib qho ntawm cov qog me tshaj plaws, tab sis tseem ceeb heev hauv koj lub cev. Hnub no peb yuav tham txog hypopituitarism , ib qho mob tsis tshua muaj uas tshwm sim hauv cov qog pituitary . Tsis txhob txhawj, peb yuav tham txog qhov no yooj yim, hauv txoj kev uas koj tuaj yeem nkag siab.

Hypopituitarism yog dab tsi?

Hais yooj yim xwb, hypopituitarism yog thaum koj lub qog pituitary tsis tsim cov tshuaj hormones txaus. Tam sim no koj yuav xav paub tias cov tshuaj hormones no yog dab tsi. Cov tshuaj hormones zoo li cov neeg xa xov uas nqa cov lus kom peb lub cev ua haujlwm tau zoo. Cov tshuaj hormones pituitary tswj ntau yam, suav nrog peb cov metabolism , kev loj hlob ntawm lub cev, kev loj hlob ntawm kev sib deev, thiab kev yug me nyuam.

Xav txog nws zoo li lub chaw hais kom ua me me hauv peb lub cev, lub qog pituitary. Tab sis nws tsis ua haujlwm ib leeg xwb. Nws tau txais kev pab los ntawm lwm qhov tseem ceeb ntawm lub hlwb hu ua hypothalamus . Lub hypothalamus qhia rau lub qog pituitary, "Okay, tso cov tshuaj hormones tam sim no." Lub hypothalamus kuj tswj cov khoom xws li ntshav siab, lub plawv dhia, qhov kub ntawm lub cev, thiab kev zom zaub mov. Yog li, yog tias muaj kev puas tsuaj lossis kab mob rau lub qog pituitary lossis hypothalamus, koj tuaj yeem tsim hypopituitarism.

Tus mob no tuaj yeem tshwm sim sai sai, txawm tias tom qab muaj xwm txheej. Los yog nws tuaj yeem tshwm sim maj mam dhau ntau lub hlis lossis ntau xyoo. Feem ntau, cov neeg no yuav tsum tau noj tshuaj rau tas lawv lub neej kom tswj tau lawv cov tsos mob. Tab sis tsis txhob txhawj, koj tus kws kho mob yuav saib xyuas koj ze thiab muab kev kho mob tsim nyog.

Puas muaj ntau hom hypopituitarism sib txawv?

Yog, nws muaj ob hom tseem ceeb. Ib hom yog raws li seb tsis muaj cov tshuaj hormones ntau npaum li cas .

• Tsis muaj zog pituitary cais tawm: Hauv qhov no, tsuas yog ib qho tshuaj hormones pituitary xwb thiaj tsis muaj zog.
• Tsis muaj ntau yam tshuaj hormones pituitary: Qhov no yog thaum ob lossis ntau dua cov tshuaj hormones pituitary tsis txaus.
• Panhypopituitarism: Qhov no yog ib qho mob tsis loj heev uas tag nrho cov tshuaj hormones uas tsim los ntawm lub qog pituitary raug txo qis.

Tom ntej no, lawv raug cais raws li qhov ua rau thiab seb lub qog pituitary raug cuam tshuam li cas :

• Primary hypopituitarism: Qhov no yog tshwm sim los ntawm kev puas tsuaj lossis kab mob uas cuam tshuam ncaj qha rau lub qog pituitary.
• Kev mob qog ntshav theem ob: Qhov no yog tshwm sim los ntawm kev puas tsuaj lossis kab mob rau lub hypothalamus. Nco ntsoov, lub hypothalamus yog qhov muab cov lus qhia rau lub qog pituitary.
• Idiopathic hypopituitarism: Qee zaum tsis pom qhov ua rau.

Cov tsos mob ntawm Hypopituitarism yog dab tsi?

Cov tsos mob sib txawv nyob ntawm seb cov tshuaj hormones twg tsis txaus . Cov yam hauv qab no kuj ua lub luag haujlwm:

• Koj poj niam txiv neej .
• Koj muaj hnub nyoog thaum tus mob no pib .
• Qhov ua rau mob hypopituitarism.
• Cov tshuaj hormones txo qis sai npaum li cas .

Tam sim no cia peb saib seb cov tsos mob tshwm sim thaum txhua yam tshuaj hormones qis.

Cov tsos mob ntawm Kev Loj Hlob Hormone (GH) Tsis Txaus

Rau cov menyuam mos tshiab:

• Cov ntshav qab zib qis (Hypoglycemia) .
• Muaj ib tug qau me me txawv txav (Micropenis) rau txiv neej.

Rau cov menyuam yaus:

• Kev loj hlob qeeb heev los yog tsis loj hlob li. Piv txwv li, yog tias koj tus menyuam zoo li tsis loj hlob siab dua li lwm tus menyuam hnub nyoog lawv, qhov no yuav yog ib qho cim qhia txog qhov no.
• Qhov siab luv .
• Kev loj hlob ntawm kev sib deev qeeb lossis tsis muaj thaum lub sijhawm tiav nkauj tiav nraug.

Rau cov neeg laus:

• qaug zog heev tas li . Zoo li lub roj teeb tuag lawm.
• Tsis tshua muaj kev zoo siab thiab txaus siab rau lub neej.
• Txo kev ua ub ua no thiab kev ntshaw kev sib deev .
• Muaj roj ntau ntxiv, tshwj xeeb tshaj yog nyob ib ncig ntawm lub duav .
• Txo kev kam rau txias thiab cua sov .
• Cov leeg nqaij txo qis .
• Txo lub zog thiab kev ua siab ntev thaum ua si.

Cov tsos mob ntawm qhov tsis txaus ntawm Thyroid-Stimulating Hormone (TSH)

Rau cov menyuam mos tshiab:

• Cov leeg nqaij tsis muaj zog (cov ceg tsis muaj sia).
• Lub cev kub qis (Hypothermia) .
• Xav tias o .
• Quaj nrog lub suab qhuj qhuj, tsis muaj suab .

Rau cov menyuam yaus thiab cov neeg laus:

Cov tsos mob ntawm qhov no zoo ib yam li cov mob hypothyroidism , vim tias TSH hormone ua rau lub qog thyroid tsim nws cov tshuaj hormones.

• Qaug zog heev .
• Tawv nqaij qhuav thiab plaub hau nyias/poob .
• Cem quav .
• Qhov hnyav nce .
• Cov leeg tsis muaj zog .
• Txo qis peev xwm tiv taus txias .
• Cov mob hlwb xws li kev nyuaj siab .
• Cov poj niam yuav muaj kev coj khaub ncaws tsis xwm yeem lossis los ntshav ntau dua li qub .

Cov tsos mob ntawm Follicle-Stimulating Hormone (FSH) thiab/lossis Luteinizing Hormone (LH) tsis txaus

FSH thiab LH yog cov tshuaj hormones hu ua gonadotropins . Cov no cuam tshuam ncaj qha rau peb lub cev kev yug me nyuam .

Rau cov menyuam tub yug tshiab:

• Muaj ib tug qau me me txawv txav (Micropenis) rau txiv neej.
• Cov noob qes tsis nqis los .

Rau cov menyuam yaus:

• Tsis muaj kev loj hlob ntawm lub mis hauv cov ntxhais.
• Cov tub hluas lub noob qes tsis loj hlob .
• Lub cev tsis muaj kev nce siab sai sai (kev loj hlob sai) thaum lub sijhawm laus.

Rau cov txiv neej:

• Txo kev ntshaw kev sib deev .
• Qaug zog heev .
• Kev tsis muaj menyuam .
• Kev ua haujlwm tsis zoo ntawm erectile .
• Poob ntawm cov plaub hau ntawm lub ntsej muag lossis lub cev .

Rau cov poj niam:

• Tsis muaj kev sib deev .
• Qaug zog heev .
• Kev tsis muaj menyuam .
• Kub hnyiab - Kev hnov ​​​​​​mob kub hnyiab hauv lub cev.
• Kev coj khaub ncaws tsis tu ncua lossis kev coj khaub ncaws tsis tu ncua (Amenorrhea) .
• Poob cov plaub hau hauv qab plab .
• Tsis muaj peev xwm tsim cov kua mis tom qab yug menyuam .

Cov tsos mob ntawm Adrenocorticotropic Hormone (ACTH lossis Corticotropin) Deficiency

Rau cov menyuam mos tshiab:

• Cov ntshav qab zib qis (Hypoglycemia) .
• Qis heev nce phaus (Tsis loj hlob zoo) . Zoo li tus menyuam tsis tau noj txawm tias nws haus mis txaus los xij.
• Qaug dab peg .
• Tawv nqaij daj (Jaundice) .

Rau cov menyuam yaus thiab cov neeg laus:

• Qaug zog heev .
• Poob phaus yam tsis muaj laj thawj .
• Ntshav siab qis (Hypotension) .
• Xeev siab thiab ntuav .
• Cov ntshav qab zib qis (Hypoglycemia) .
• Kev tsis meej pem, kev tsis nco qab .

Cov tsos mob ntawm Prolactin deficiency

Qhov tseem ceeb ntawm qhov no yog qhov tsis muaj kua mis tom qab yug me nyuam .

Cov tsos mob ntawm Oxytocin Deficiency

• Teeb meem pub niam mis tom qab yug tus menyuam.
• Nyuaj siab sib raug zoo nrog tus menyuam tom qab yug los.
• Tsis muaj kev khuv leej rau lwm tus neeg txoj kev txom nyem.
• Nyuaj siab sib tham nrog lwm tus.

Cov tsos mob ntawm Antidiuretic Hormone (ADH lossis Vasopressin lossis Arginine Vasopressin) Deficiency

Rau cov menyuam mos tshiab:

• Ntuav .
• Kub taub hau tsis paub ua li cas .
• Quaj ntau dhau .
• Kev poob phaus .
• Cem quav .
• Ua kom daim ntaub pam ntub ntau zaus (Daim ntaub pam ntub heev) .

Rau cov menyuam yaus:

• Nyuaj siab kawm siv chav dej .
• Tso zis pw .
• Nkees sai sai .

Rau cov neeg laus:

• Tso zis ntau zaus .
• Kev nqhis dej ntau dhau .
• Kev tsis sib npaug ntawm cov electrolyte .

Tseem Ceeb: Tsis txhob txhawj yog tias koj muaj ib lossis ob qho ntawm cov tsos mob no, tab sis yog tias lawv tseem muaj, nws yog qhov zoo tshaj plaws los nrhiav kev pab kho mob.

Dab tsi yog cov ua rau hypopituitarism?

Muaj ntau yam ua rau mob no. Tej zaum cov kws kho mob kuj tsis paub meej tias yog vim li cas. Feem ntau, nws muaj peb yam tseem ceeb ua rau mob no:

1. Nias lub qog pituitary lossis hypothalamus.

2. Kev puas tsuaj rau lub qog pituitary lossis hypothalamus.

3. Muaj ib qho mob tsis tshua muaj lossis lwm yam kab mob uas ua rau hypopituitarism.

Cov mob uas cuam tshuam rau lub qog pituitary lossis hypothalamus

Cov mob uas tuaj yeem tso siab rau cov qhov no ntawm lub hlwb thiab ua rau hypopituitarism muaj xws li:

• Cov qog pituitary adenomas: Cov no yog cov qog benign uas tsim nyob rau hauv lub qog pituitary. Lawv tuaj yeem hloov txoj kev tsim cov tshuaj hormones.
• Cov qog nqaij hlav hauv lub hlwb: Cov qog nqaij hlav uas tsim nyob ze ntawm hypothalamus lossis pituitary gland tuaj yeem cuam tshuam kev tsim cov tshuaj hormones.
• Lymphocytic hypophysitis (LH): Qhov no yog ib qho mob tsis tshua muaj. Ntawm no, cov hlwb hu ua lymphocytes nkag mus rau hauv lub qog pituitary. (LH no yuav tsum tsis txhob tsis meej pem nrog Luteinizing Hormone uas tau hais ua ntej, puas yog?!)
• Pituitary lossis hypothalamus sarcoidosis: Sarcoidosis yog ib yam kab mob uas ua rau o.

Cov xwm txheej uas ua rau puas tsuaj rau lub qog pituitary lossis hypothalamus

• Kev Phais Mob: Tej yam teeb meem thaum lub sij hawm phais hlwb (tshwj xeeb yog kev phais kom tshem tawm cov pituitary adenomas).
• Kev kho mob hluav taws xob: Kev kho mob hluav taws xob siv los kho cov kev kho mob qog noj ntshav yav dhau los lossis pituitary adenomas.
• Kev raug mob taub hau loj heev (Kev raug mob hlwb loj heev - TBI):Tej yam xws li kev sib tsoo tsheb, kev ntog, thiab kev raug mob hauv kev ua si.
• Pituitary apoplexy: Kev puas tsuaj ntawm cov ntaub so ntswg pituitary tam sim ntawd.

Cov mob tsis tshua muaj

• Kab mob hemochromatosis uas los ntawm noob caj noob ces: Qhov no yog ib qho mob uas los ntawm noob caj noob ces. Nws ua rau muaj hlau ntau dhau hauv cov ntshav. Qhov no tuaj yeem ua rau lub qog pituitary puas tsuaj.
• Kab mob meningitis: Txawm hais tias tsis tshua muaj, hypopituitarism tuaj yeem tshwm sim ua ib qho teeb meem ntawm kab mob meningitis.
• Kev hloov pauv caj ces: Qee qhov mob caj ces tsis tshua muaj tuaj yeem ua rau cov tshuaj hormones pituitary tsis txaus.

Cov yam ua rau muaj kev pheej hmoo yog dab tsi?

Cov xwm txheej lossis cov xwm txheej hauv qab no yuav yog cov yam ua rau muaj kev pheej hmoo rau hypopituitarism:

• Tau dhau kev kho mob qog noj ntshav thiab kev kho mob hluav taws xob yav dhau los.
• Kev raug mob taub hau lossis lub hlwb: Nruab nrab ntawm 27% thiab 32% ntawm cov neeg uas tau raug mob taub hau (TBI) tsim hypopituitarism.
• Kab mob ntshav liab ntshav (sickle cell anemia): Kab mob no ua rau cov tshuaj hormones hauv lub pituitary tsis txaus.
• Kab mob ntshav qab zib hom 1: Kev puas tsuaj rau cov hlab ntsha thiab cov hlab ntsha uas tshwm sim los ntawm kab mob ntshav qab zib hom 1 uas tsis tswj tau tuaj yeem ua rau muaj tus mob no.
• Cev xeeb tub thiab yug menyuam: Kev los ntshav ntau dhau tom qab yug menyuam tuaj yeem ua rau lub qog pituitary puas tsuaj. Qhov mob no hu ua Sheehan syndrome .

Tej yam teeb meem uas yuav tshwm sim

Cov tshuaj hormones tsis txaus uas nrog rau hypopituitarism tuaj yeem ua rau muaj lwm yam mob. Cov teebmeem no sib txawv nyob ntawm cov tshuaj hormones uas tsis txaus. Nov yog qee qhov piv txwv:

• Qhov tsis muaj GH (kev loj hlob hormone) tuaj yeem ua rau rog dhau , roj cholesterol ntau , thiab metabolic syndrome .
• Qhov tsis muaj cov tshuaj hormones estrogen (vim yog tsis muaj FSH) tuaj yeem ua rau osteoporosis ( thinning ntawm cov pob txha) rau cov poj niam.
• Qhov tsis txaus ACTH tuaj yeem ua rau muaj teeb meem adrenal , uas yog qhov xwm txheej ceev uas hem txoj sia.

Yuav ua li cas thiaj kuaj tau tus mob no?

Koj tus kws kho mob yuav xaj ib qho ntawm cov kev kuaj no los kuaj mob hypopituitarism:

• Kev kuaj ntshav rau cov tshuaj hormones: Nyob ntawm koj cov tsos mob, koj tus kws kho mob yuav xaj kev kuaj ntshav uas ntsuas ntau yam tshuaj hormones.
• Kev kuaj mob hormone: Hauv qhov kev kuaj mob no, koj tus kws kho mob yuav muab tshuaj rau koj los pab koj lub qog pituitary kom tso cov hormone uas koj tab tom kuaj tawm. Tom qab ntawd, yuav muab cov ntshav coj mus kuaj thiab xa mus rau chav kuaj mob.
• Kev kuaj mob insulin: Qhov no tuaj yeem kuaj pom cov tshuaj hormones loj hlob (GH) thiab ACTH tsis txaus.
• Kev ntsuam xyuas osmolality rau cov ntshav thiab zis: Qhov no kuaj rau qhov tsis txaus antidiuretic hormone (ADH).
• Kev Ntsuas MRI (Magnetic Resonance Imaging): Kev ntsuas MRI thaij duab kom ntxaws ntawm sab hauv koj lub cev. Kev ntsuas MRI ntawm lub hlwb yog suav tias yog txoj hauv kev zoo tshaj plaws los nrhiav cov qog pituitary uas ua rau hypopituitarism.
• Kev ntsuas CT ntawm lub hlwb (Computed Tomography): Qhov kev kuaj no siv tau los saib seb puas muaj qog hauv lub hlwb lossis pituitary adenoma ua rau muaj qhov mob no.

Yuav kho tus mob hypopituitarism li cas?

Txawm hais tias tsis muaj kev kho mob los, nws tuaj yeem kho tau . Kev kho mob nyob ntawm seb cov tshuaj hormones twg tsis txaus thiab dab tsi ua rau koj tus mob . Koj pab neeg kho mob yuav pab koj tsim ib txoj kev npaj kho mob uas zoo tshaj plaws rau koj. Cov kev xaiv kho mob feem ntau suav nrog:

• Kev kho mob hloov tshuaj hormones: Lub hom phiaj ntawm qhov no yog los kho cov tshuaj hormones hauv lub pituitary kom rov qab zoo li qub. Feem ntau, yuav tsum noj tshuaj rau tas koj lub neej.
• Kev Phais Mob: Cov neeg uas muaj cov pituitary adenomas yuav tsum tau phais kom tshem tawm lawv.
• Kev kho mob hluav taws xob: Kev kho mob hluav taws xob tuaj yeem pab txo cov pituitary adenomas.

Koj tus kws kho mob kuj tseem yuav pom zoo kom koj nqa daim npav ID kho mob lossis lub kauj tes nrog koj txhua lub sijhawm, yog tias muaj xwm txheej ceev.

Yuav ua li cas thiaj paub tias hypopituitarism yog dab tsi?

Qhov kev xav tau sib txawv, nyob ntawm cov yam no:

• Koj lub hnub nyoog thaum koj cov tsos mob pib .
• Qhov laj thawj rau koj qhov xwm txheej .
• Cov tshuaj hormones qis npaum li cas raug cuam tshuam.
• Koj lub cev teb li cas rau kev kho mob .

Muaj coob tus neeg uas muaj hypopituitarism nyob lub neej noj qab nyob zoo. Txawm li cas los xij, yog tias muaj kev puas tsuaj rau lub pituitary mus sij hawm ntev, lub neej ntev yuav luv dua li ib tus neeg uas muaj hnub nyoog zoo ib yam uas tsis muaj tus mob no. Txawm li cas los xij, lub neej ntev feem ntau tsis raug txo rau cov neeg uas ua raws li txoj kev kho mob kom zoo .

Yog tias muaj xwm txheej ceev? Yog tias hypopituitarism tshwm sim sai sai, hnyav heev, thiab tsis kho, nws tuaj yeem yog xwm txheej ceev kho mob thiab ua rau tuag tau. Yog li ntawd, yog tias koj pom cov tsos mob, mus ntsib kws kho mob tam sim ntawd.

Kuv yuav tsum mus ntsib kws kho mob thaum twg?

Feem ntau, hypopituitarism yuav tsum tau saib xyuas cov tshuaj hormones uas cuam tshuam tas mus li . Mus ntsib koj tus kws kho mob tsis tu ncua kom paub tseeb tias koj txoj kev npaj kho mob ua haujlwm.Yog koj muaj cov tsos mob tshiab lossis ua rau txhawj xeeb, hu rau koj tus kws kho mob sai li sai tau.

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Yog tias koj raug kuaj pom tias muaj hypopituitarism, koj yuav xav nug koj tus kws kho mob cov lus nug no:

• Kuv muaj hom hypopituitarism twg?
• Cov tshuaj hormones twg tsis txaus hauv kuv?
• Vim li cas ho ua li no?
• Kuv muaj cov kev kho mob twg?
• Puas muaj tej yam tshwm sim los ntawm kuv txoj kev kho mob?
• Kuv yuav tsum noj tshuaj ntev npaum li cas?
• Qhov no puas yuav cuam tshuam rau kuv qhov kev muaj menyuam?
• Qhov no puas yuav cuam tshuam rau kuv cev xeeb tub?
• Qhov no puas tshwm sim rau kuv cov menyuam thiab?

Thaum kawg, nco ntsoov (Cov Lus Coj Mus Tsev)

Kev kuaj mob tshiab tuaj yeem ua rau ntshai, tab sis tsis txhob ntshai nug koj tus kws kho mob txog hypopituitarism. Feem ntau, kev kho mob tas mus li thiab kev saib xyuas cov tshuaj hormones yog qhov tsim nyog. Yog vim li cas nws thiaj li tseem ceeb kom mus ntsib koj tus kws kho mob tsis tu ncua. Yog tias koj muaj cov tsos mob tshiab lossis txhawj xeeb, hu rau koj tus kws kho mob. Lawv nyob ntawd los pab koj. Yog tias koj tswj hwm zoo, koj tuaj yeem ua neej nyob zoo thiab nquag.

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