Tej zaum koj yuav paub tias Ankylosing Spondylitis (AS) yog ib yam mob uas yuav ua rau koj mob mus tas li. Koj paub tias nws nyuaj npaum li cas los kho koj tus mob nraub qaum thiab mob thaum sawv ntxov. Tiam sis, muaj xov xwm zoo. Txawm hais tias tus kab mob no kho tsis tau tag nrho los xij, peb tuaj yeem tswj nws cov tsos mob nrog kev siv tshuaj, kev tawm dag zog, thiab kev noj qab haus huv. Cov tshuaj no tuaj yeem pab tiv thaiv lossis ncua qhov kev loj hlob ntawm cov teeb meem nraub qaum.
Kauj Ruam Ib: NSAIDs - rau qhov mob thiab o
Thaum koj mus ntsib kws kho mob, qhov no yog thawj hom tshuaj uas lawv yuav sim muab rau koj rau qhov mob no. Peb hu cov tshuaj Nonsteroidal Anti-inflammatory Drugs, lossis (NSAIDs) luv luv. Txawm hais tias qee cov no tuaj yeem yuav tau ntawm lub txee muag tshuaj, qee qhov xav tau daim ntawv yuav tshuaj los ntawm kws kho mob.
Hais yooj yim xwb, cov tshuaj no ua haujlwm los ntawm kev txwv tsis pub tsim cov tshuaj hu ua prostaglandins hauv peb lub cev uas ua rau mob. Qhov no txo koj qhov mob thiab o. Kev noj cov tshuaj no thaum hmo ntuj, tshwj xeeb tshaj yog, tuaj yeem pab koj pw tsaug zog zoo dua thiab txo qhov mob nraub qaum thaum sawv ntxov.
Qhov tseem ceeb tshaj plaws yog noj cov tshuaj no raws li qhov ntau npaum li cas thiab rau lub sijhawm uas koj tus kws kho mob tau sau tseg. Tsis txhob tsum lossis hloov qhov ntau npaum li cas thaum twg koj xav tau.
| Hom tshuaj (NSAID) | Cov kev mob tshwm sim thiab yam yuav tsum paub |
|---|---|
| Cov tshuaj no yuav ua rau mob plab yog tias siv ntev. Piv txwv li:
Yog li ntawd, koj tus kws kho mob yuav sau ntawv rau lwm yam tshuaj (xws li tshuaj antacids) los tiv thaiv koj lub plab nrog rau cov tshuaj no. Yog tias koj muaj keeb kwm ntawm kab mob plawv, koj yuav tsum qhia rau koj tus kws kho mob. Qee cov NSAIDs yuav ua rau muaj kev pheej hmoo ntawm kev mob plawv lossis mob hlwb me ntsis. |
Kauj Ruam Ob: DMARDs - Cov Tshuaj Kho Mob Rheumatic Uas Hloov Kho Kab Mob
Qee zaum cov tshuaj NSAIDs ib leeg xwb yuav tsis txaus los tswj koj cov tsos mob. Yog tias qhov ntawd yog qhov tseeb, koj tus kws kho mob yuav sau ib hom tshuaj rau koj hu ua (DMARDs) , uas sawv cev rau Disease-Modifying Antirheumatic Drugs . Txawm hais tias lub npe yuav zoo li nyuaj, qhov nws ua yog yooj yim. Nws ua haujlwm los ntawm kev txwv kev puas tsuaj rau koj cov pob qij txha thiab cov nqaij uas tshwm sim los ntawm kev o. Cov no ua rau qeeb qeeb ntawm kev loj hlob ntawm tus kab mob.
| Hom tshuaj (DMARD) | Tej yam yuav tsum paub tshwj xeeb |
|---|---|
| Sulfasalazine | Qhov no noj ua ib lub tshuaj. Ib txhia neeg yuav mob taub hau, o, xeev siab, thiab mob qhov ncauj. Tsis tshua muaj, cov pob txha yuav raug cuam tshuam, yog li koj tus kws kho mob yuav kuaj koj cov ntshav thaum muab cov tshuaj no rau koj. |
| Methotrexate | Qhov no los ua ib lub tshuaj lossis ua ib qho tshuaj txhaj uas koj tuaj yeem muab rau koj tus kheej. Koj yuav tsum tau noj ib lub tshuaj folic acid nrog qhov no. Qhov no yog kom tsis txhob muaj cov kev mob tshwm sim xws li mob qhov ncauj thiab xeev siab. Vim tias qhov no yog ib qho tshuaj muaj zog me ntsis, koj tus kws kho mob yuav kuaj xyuas koj cov ntshav thiab lub siab ua haujlwm tsis tu ncua. Cov tshuaj no tsis haum rau cov poj niam cev xeeb tub lossis cov neeg uas tab tom sim cev xeeb tub. |
Corticosteroids - kev pab sai rau cov pob qij txha mob
Cov no yog ib hom tshuaj steroid. Koj tus kws kho mob tuaj yeem muab tshuaj steroid rau koj, xws li "Prednisone", ncaj qha rau hauv koj cov pob qij txha uas mob heev thiab o. Qhov no yuav pab txo qhov mob thiab o tam sim ntawd.
Tiam sis nco ntsoov, qhov no tsis yog kev kho mob uas muab rau tag nrho lub cev. Tsis tas li ntawd, cov tshuaj txhaj no tsis tuaj yeem muab ntau zaus. Feem ntau, tus kws kho mob tsuas muab cov tshuaj txhaj no ob peb zaug hauv ib xyoos, nrog rau lub sijhawm ncua sijhawm ob peb lub hlis.
Biologics - txoj kev kho mob tshiab thiab muaj zog tshaj plaws
Yog tias lwm yam kev kho mob tsis ua haujlwm rau koj, koj tus kws kho mob yuav qhia koj txog qhov kev kho mob tshiab no. Cov no hu ua biologics . Lawv yog ua los ntawm cov hlwb uas muaj sia nyob. Tshwj xeeb, cov tshuaj no thaiv cov protein hu ua cytokines uas ua rau muaj kev o hauv peb lub cev tiv thaiv kab mob. Qhov no yog kev kho mob uas tsom mus rau qhov mob. Cov no tuaj ua cov tshuaj txhaj. Ib txhia ntawm lawv koj tuaj yeem muab rau koj tus kheej hauv tsev.
Cov tshuaj TNF inhibitors
Cov no yog ib hom tshuaj biologic uas feem ntau siv rau AS. TNF sawv cev rau ib qho protein hu ua "Tumor Necrosis Factor". Cov tshuaj no kho qhov o ntawm tus txha nraub qaum, pob qij txha, qhov muag, thiab txoj hnyuv. Lawv kuj tseem tuaj yeem ua rau qeeb qeeb ntawm kev loj hlob ntawm AS.
- Adalimumab (Humira)
- Certolizumab pegol (Cimzia)
- Etanercept (Enbrel)
- Golimumab (Simponi)
- Infliximab (Remicade)
Cov tshuaj tiv thaiv Interleukin (IL-17)
Yog tias TNF inhibitors tsis ua haujlwm, koj tus kws kho mob yuav pib koj rau hom no.
- Ixekizumab (Taltz)
- Secukinumab (Cosentyx)
Cov tshuaj Biologics yog cov tshuaj muaj zog heev. Yog vim li ntawd lawv thiaj muaj cov kev mob tshwm sim uas yuav tsum tau paub. Koj tus kws kho mob yuav piav qhia txhua yam no rau koj ua ntej koj pib kho mob.
| Cov kev pheej hmoo tseem ceeb thiab cov kev phiv ntawm cov tshuaj biologics | |
|---|---|
| Kev pheej hmoo ntawm kev kis kab mob | Vim tias cov tshuaj no ua rau lub cev tiv thaiv kab mob tsis muaj zog, ua rau muaj kev pheej hmoo ntawm kev kis kab mob, tshwj xeeb yog mob ntsws (TB). Yog li ntawd, nws yog ib qho tseem ceeb uas yuav tsum tau kuaj mob ntsws ua ntej pib noj cov tshuaj no. |
| Lwm yam kev pheej hmoo | - Kev pheej hmoo ntawm mob qog nqaij tawv nce me ntsis. - Muaj feem yuav mob qog nqaij hlav lymphoma ntau ntxiv rau cov menyuam yaus. - Yog tias koj twb muaj tus kab mob plab hnyuv (IBD) lawm, koj cov tsos mob yuav hnyav zuj zus. |
Yog tias koj tsis xis nyob tom qab li 3 lub hlis ntawm kev kho mob no, koj tus kws kho mob yuav txiav txim siab tso tseg cov tshuaj lossis hloov koj mus rau lwm yam tshuaj biologic.
Kev cia siab rau kev kho mob yav tom ntej
Cov kws tshawb fawb tam sim no tab tom ua haujlwm los nrhiav cov tshuaj tshiab uas tuaj yeem thim rov qab AS. Lawv kuj tseem tab tom kawm txog seb peb cov noob caj noob ces cuam tshuam li cas rau tus kab mob. Kev tshawb fawb no tuaj yeem ua rau muaj kev kho mob zoo dua uas tshwj xeeb rau koj yav tom ntej.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Ankylosing Spondylitis (AS) yog ib yam mob uas yuav kho tau mus ib txhis, tab sis nws tuaj yeem tswj tau zoo nrog kev kho mob thiab kev ua neej zoo.
- Feem ntau kev kho mob pib nrog NSAIDs. Yog tias cov no tsis tswj tau qhov mob, cov tshuaj xws li DMARDs lossis biologics raug siv.
- Ntseeg koj tus kws kho mob. Ua raws li nws cov lus qhia kom meej. Mus rau cov chaw kho mob raws sijhawm thiab mus kuaj mob.
- Tsis txhob tsum noj koj cov tshuaj lossis hloov qhov ntau npaum li cas ntawm koj tus kheej. Yog tias koj muaj kev txhawj xeeb, nrog koj tus kws kho mob tham.
- Nrog rau kev siv tshuaj, kev tawm dag zog kom zoo thiab kev noj zaub mov zoo yog ob yam tseem ceeb los tswj tus kab mob no.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus