Thaum nws los txog rau tus kab mob ntshav qab zib , yuav luag tsis muaj leej twg hauv peb lub tebchaws uas tsis paub txog nws. Muaj ntau tus neeg xav tias tsuas muaj ob hom kab mob ntshav qab zib xwb , uas yog Hom 1 thiab Hom 2. Tab sis koj puas paub tias muaj lwm hom kab mob ntshav qab zib tshwj xeeb ntxiv rau qhov no? Qhov ntawd yog qhov peb hu ua MODY, lossis 'Maturity-Onset Diabetes of the Young'. Qhov no tsis tshua muaj, thiab nws yog los ntawm noob caj noob ces . Nws yog ib qho tseem ceeb heev uas yuav tsum txheeb xyuas qhov no kom raug, vim tias kev kho mob rau qhov no tuaj yeem txawv ntawm lwm hom kab mob ntshav qab zib.
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Vim li cas MODY thiaj tshwm sim? Dab tsi yog qhov ua rau?
Hais yooj yim xwb, MODY yog tshwm sim los ntawm kev hloov pauv, lossis kev hloov pauv, hauv ib lub noob caj noob ces hauv peb lub cev. Qhov no yog qhov sib txawv tseem ceeb ntawm MODY thiab ntshav qab zib hom 1 thiab hom 2. Lwm hom ntshav qab zib yog tshwm sim los ntawm kev sib xyaw ua ke ntawm ntau yam, xws li ntau lub noob caj noob ces, kev rog dhau , thiab kev ua neej tsis zoo. Tab sis MODY yog tshwm sim los ntawm ib lub noob caj noob ces.
, (pancreas) (insulin) . , . .
Leej twg yuav muaj tus mob no ntau dua?
MODY yog ib yam kab mob uas tau txais los ntawm noob caj noob ces . Qhov no txhais tau tias yog tias ib tug neeg hauv koj tsev neeg muaj MODY, koj yuav muaj feem ntau dua los mob. Piv txwv li, yog tias koj niam lossis koj txiv muaj MODY, koj muaj feem yuav mob li 50% . Qhov no yog ib qho kev sib txuas ntawm noob caj noob ces uas muaj zog heev. Hauv qee tsev neeg, tus kab mob no tuaj yeem pom tau rau txhua peb tiam neeg: yawg koob yawm txwv, niam, txiv, thiab menyuam.
Feem ntau cov neeg hluas hnub nyoog qis dua 35 xyoo yuav kuaj pom tus kab mob no. Txawm li cas los xij, nws tuaj yeem tshwm sim rau txhua lub hnub nyoog.
Qhov tseem ceeb yog tias, tsis zoo li tus kab mob ntshav qab zib hom 2, cov neeg uas muaj tus kab mob MODY feem ntau tsis rog dhau, thiab lawv tsis muaj ntshav siab. Lawv tuaj yeem nyob hauv qhov hnyav noj qab nyob zoo.
Koj yuav paub li cas yog tias koj muaj tus kab mob MODY? Cov tsos mob yog dab tsi?
Cov tsos mob ntawm MODY nyob ntawm seb koj muaj qhov tsis zoo li cas hauv cov noob caj noob ces (gene). Tej zaum koj yuav tsis muaj tsos mob dab tsi li. Tab sis feem ntau, tus kab mob no qeeb qeeb. Tej zaum koj yuav muaj ntshav qab zib ntau xyoo, thiab cov tsos mob no yuav tshwm sim tom qab:
- Nqhis dej thiab tshaib plab tas li
- Yuav tsum tau tso zis ntau zaus dua li niaj zaus
- Pom kev tsis meej
- Feem ntau tshwm sim ntawm cov kab mob ntawm daim tawv nqaij lossis cov kab mob poov xab
- Kev poob phaus yam tsis muaj laj thawj tshwj xeeb
- qaug zog ntau zaus
Yog tsis kho ces yuav muaj teeb meem dab tsi tshwm sim?
Ib yam li lwm hom mob ntshav qab zib, MODY muaj cov ntshav qab zib ntau heev. Yog tias tsis kho, cov ntshav qab zib ntau dhau mus ntev yuav ua rau muaj teeb meem loj. Qhov no kuj tshwm sim ntau hauv MODY.
- Kev puas tsuaj rau cov hlab ntsha
- Kab mob plawv
- Kev puas tsuaj rau qhov muag (uas thaum kawg tuaj yeem ua rau dig muag )
- Teeb meem ko taw
- Kab mob ntawm daim tawv nqaij ntau zaus
Yuav kuaj mob MODY li cas?
Vim tias cov tsos mob ntawm MODY tsis hnyav heev, koj lossis koj tus kws kho mob yuav tsis xav tias nws yog MODY thaum xub thawj. Thaum kuaj ntshav tas li qhia tias koj cov ntshav qab zib siab, koj tus kws kho mob yuav qhia rau koj tias koj muaj ntshav qab zib. Kauj ruam tom ntej yog nrhiav seb koj muaj hom ntshav qab zib twg.
Koj tus kws kho mob yuav saib xyuas koj tsev neeg keeb kwm mob ntshav qab zib kom meej thiab tej zaum yuav kom kuaj ntshav tshwj xeeb kom paub tseeb tias tsis muaj mob ntshav qab zib hom 1 lossis hom 2.
Raws li cov txiaj ntsig no, koj tus kws kho mob yuav hais kom kuaj xyuas cov noob caj noob ces kom paub tseeb tias koj puas muaj MODY. Qhov no suav nrog kev coj DNA los ntawm cov qaub ncaug lossis cov ntshav thiab kuaj nws hauv chav kuaj mob kom pom tias puas muaj kev hloov pauv hauv cov noob caj noob ces uas ua rau muaj MODY.
Yuav kho tus mob MODY li cas?
Kev kho mob rau MODY nyob ntawm seb koj muaj qhov tsis zoo nyob rau hauv hom noob caj ces twg. Qhov no yog vim li cas nws thiaj li tseem ceeb kom tau txais kev kuaj mob kom raug. Lub rooj hauv qab no teev qee hom MODY tseem ceeb thiab lawv cov kev kho mob.
| Hom MODY | Kev Kho Mob |
|---|---|
| MODY 1 thiab MODY 4 | Cov tshuaj sulfonylureas feem ntau siv ua cov tshuaj kho mob ntshav qab zib. Cov tshuaj no ua rau lub pancreas tsim cov insulin ntau dua. Tej zaum ib txhia neeg kuj yuav tsum tau txhaj tshuaj insulin. |
| MODY 2 | Qhov no yog ib qho mob me me xwb. Feem ntau nws tuaj yeem tswj tau los ntawm kev noj zaub mov thiab kev tawm dag zog . Feem ntau, tsis tas yuav siv tshuaj. |
| MODY 3 | Thaum pib mob, kev noj zaub mov tuaj yeem tswj tau. Raws li lub sijhawm dhau mus, tej zaum yuav xav tau cov tshuaj sulfonylurea thiab txhaj tshuaj insulin tom qab. |
| MODY 5 | Qhov no yuav tsum tau txhaj tshuaj insulin . Qhov no yog ib hom mob tsis tshua muaj. Nws kuj tseem tuaj yeem cuam tshuam rau lwm yam kabmob, xws li lub raum. Yog li ntawd, cov teeb meem xws li cov cysts raum lossis lub raum tsis ua haujlwm kuj yuav tsum tau kho. |
| MODY 6 | Feem ntau hom no tshwm sim thaum muaj hnub nyoog li ntawm 40 xyoo. Cov tshuaj insulin yog muab los kho. |
Raws li koj pom, kev kho mob sib txawv nyob ntawm hom mob MODY. Yog li, yog tias koj lossis ib tug neeg hauv tsev neeg muaj mob ntshav qab zib, tshwj xeeb tshaj yog tias nws tshwm sim thaum nws tseem hluas thiab tsis rog dhau, nws yog ib qho tseem ceeb heev uas yuav tsum tham nrog koj tus kws kho mob txog nws.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- MODY yog ib hom kab mob ntshav qab zib uas txawv ntawm Hom 1 thiab Hom 2 thiab yog tshwm sim los ntawm cov caj ces.
- Qhov no kis mus los ntawm ib tiam dhau ib tiam thiab feem ntau tshwm sim rau cov neeg hluas, cov neeg rog.
- Vim tias cov kev kho mob sib txawv nyob ntawm hom mob MODY, nws yog ib qho tseem ceeb heev kom tau txais kev kuaj mob kom raug.
- Yog tias tus kab mob ntshav qab zib muaj nyob rau ntau tiam neeg hauv koj tsev neeg, nco ntsoov nrog koj tus kws kho mob tham txog nws.
- Txawm yog hom ntshav qab zib twg los xij, nws yog ib qho tseem ceeb uas yuav tsum ua raws li cov lus qhia kho mob kom meej meej kom tsis txhob muaj teeb meem.
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