Bɔku tɛm yu kin fil taya, yu taya, ɔ yu kin lɛf fɔ it bɔku bɔku it dɛn? We yu go to dɔktɔ, i kin disayd fɔ chɛk yu ɔmon dɛn. Speshal wan, di ɔmon we dɛn kɔl kɔtisol. So, di men tεst we dεn kin du fכ chεk if yu kכtisol lεvεl dεm nכmal na di ACTH Stimulεshכn Tεst. Pan ɔl we di nem kin tan lɛk se i kɔmplikt smɔl, fɔ tru, i rili simpul. Mek wi tok abaut am ol tide.
Fɔ tɔk am simpul wan, wetin na dis ACTH Stimulation Test?
Dis na tɛst we dɛn kin du fɔ mɛn pipul dɛn. Fɔ tɔk klia wan, i de luk aw yu tu ɔgan dɛn we dɛn kɔl adrenal gland de ansa wan ɔmon we dɛn kɔl ACTH (Adrenocorticotropic hormone) we de kɔmɔt na wi bren. Yu tink se dis kin mek yu kɔnfyus smɔl? Okay, mek wi tink bɔt am dis we.
Imajin se di pituitary gland na yu bren tan lɛk di manija fɔ wan big kɔmni. Di tu smɔl adrenal gland dɛn we de ɔp yu kidni dɛn tan lɛk tu wokman dɛn we de wok na da kɔmni de.
we di manija (pituitary gland) want fכ du sכmtin, i de sεnd mεsej we dεn kכl ‘ACTH’ to di wokman dεm (adrenal glands). we dεn gεt dis mεsej, di wokman dεm (adrenal gland dεm) de mek wan כmon we dεn kכl ‘kכtisol’ εn de rilis am insay di bכdi. Dis kɔtisol na wan rili impɔtant ɔmon fɔ wi bɔdi. I kin ɛp pan bɔku tin lɛk fɔ kɔntrol strɛs, kɔntrol di blɔd shuga lɛvɛl, ɛn kɔntrol blɔd prɛshɔn.
So, wetin di ACTH Stimulation Test de du na we wi injekt wan sεntetik ACTH כmon we dεn prodyuz na do (dεn kכl am cosyntropin) insay yu bכdi εn si if yu adrenal gland dεm (wokman dεm) de ansa am εn prodyuz kכtisol fayn fayn wan.
dis tεst dεn kin yus mεntal fכ no wan kכndyushכn we dεn kכl ‘adrenal insufficiency’ . dis min se di adrenal gland dεm nכ de prodyuz inof kכtisol. Dɛn sheb dis to tri kayn.
| Tayp fɔ di adrenal insufisɛns | Fɔ tɔk am simpul wan, wetin kin apin? |
|---|---|
| Praymari Adrenal Insufisɛns | Di prɔblɛm we de ya na di ‘wokman’. Dat min se, wit di adrenal gland dɛn.Sɔm damej de. I nɔ mata ɔmɔs mɛsej (ACTH) di manija (pituitary) sɛn, di wokman (adrenal) nɔ go ebul fɔ wok. Kɔtisol nɔ de kɔmɔt. Di bɛst ɛgzampul fɔ dis na di sik we dɛn kɔl Addison . |
| Sɛkɔndari Adrenal Insufisɛns | Di prɔblɛm we de ya na di ‘manija’. dat min se di pituitary gland nכ de sεnd inof mεsej (ACTH). Ivin if di wokman (adrenal) fayn, i nɔ de wok bikɔs no mɛsej nɔ de. Kɔtisol nɔ de kɔmɔt. |
| Tɛshari Adrenal Insufisɛns | Di prɔblɛm we de ya de wit di ‘bɔs ɔp di manija’. dat min se, wit di pat pan di bren we dεn kכl ‘haypothalamus’. Na de di mɛsej de kɔmɔt to di manija (pituitary) fɔ wok. If da mɛsej de nɔ kam, di manija nɔ go wok, ɛn dat mek di wokman sɛf nɔ go wok. |
Us sityueshɔn di dɔktɔ tɛl yu fɔ du dis tɛst?
Bɔku rizin dɛn kin de we mek yu dɔktɔ go tɛl yu fɔ du dis tɛst.
- If yu blɔd tɛst we yu bin dɔn du bifo tɛm sho se yu nɔ gɛt bɛtɛ kɔtisol: If yu dɔn du blɔd tɛst fɔ ɔda rizin we sho se yu gɛt kɔtsol lɛvɛl smɔl, dɛn kin aks yu fɔ du dis tɛst fɔ kɔnfirm am.
- If yu gɛt sayn dɛm fɔ adrenal insufficiency: As wi bin dɔn tɔk, if yu gɛt sayn dɛm lɛk fɔ taya ɔltɛm, fɔ lɔs yu wet, yu bɛlɛ de pen, yu nɔs, yu ed de tɔn, ɛn yu blɔd prɛshɔn de dɔŋ, dɛn kin du dis tɛst fɔ no if na dis sik de mek yu gɛt dis sik.
- If yu dɔn de tek stɛroyd fɔ lɔng tɛm: We yu de yuz glukokɔtikoyd drɔgs lɛk prɛdnisɔn fɔ lɔng tɛm, yu pituitary ɛn adrenal gland dɛn kin stɔp fɔ wok fɔ sɔm tɛm. So, afta yu dɔn stɔp fɔ tek di mɛrɛsin, dɛn kin du dis tɛst bak fɔ si if di gland dɛn de wok fayn bak.
Aw yu fɔ pripia bifo di tɛst?
Dis rili impɔtant. Yu fɔ fala yu dɔktɔ in instrɔkshɔn dɛn di rayt we. Bɔku tɛm, yu kin tɔk tin dɛn lɛk dis.
- Fast: Dɛn kin aks yu fɔ nɔ it ɔ drink ɛnitin fɔ lɛk 6 awa bifo di tɛst. Na wata nɔmɔ dɛn kin alaw.
- Di tin dɛn we yu nɔ fɔ du: Dɛn kin aks yu fɔ avɔyd fɔ du tin dɛn lɛk fɔ du ɛksɛsayz fɔ 12-24 awa bifo di tɛst.
- Fɔ it: Sɔntɛnde, dɛn kin aks yu fɔ it tin dɛn we gɛt bɔku kabɔhaydrɛt.
- Fɔ stɔp fɔ tek mɛrɛsin: Sɔm mɛrɛsin dɛn we yu kin tek (especially sterɔyd krim, pils, ɔ inhala) kin afɛkt di tɛst rizɔlt. So, yu dɔktɔ kin aks yu fɔ stɔp fɔ tek dɛn fɔ sɔm tɛm. Nɔ ɛva stɔp fɔ tek yu mɛrɛsin if yu nɔ aks yu dɔktɔ fɔs.
di kכtisol lεvεl na wi bכdi nכ de di sem כl di de. Bɔku tɛm, dɛn kin ay pas ɔl na mɔnin. So, bɔku tɛm dɛn kin du dis tɛst na mɔnin fɔ mek dɛn nɔ gɛt lay lay rizɔlt.
Okay, naw mek wi si wetin go apin di de we dɛn go du di tɛst.
Dis nɔ de mek pɔsin fred lɛk aw yu go tink. Bɔku tɛm dɛn kin du am na ɔspitul ɔ na di klinik we dɔktɔ we de mɛn di sik dɛn we de mek pɔsin in bɔdi de du. Na dis na wetin kin apin stɛp bay stɛp.
1. Fɔ tek di fɔs blɔd sɛmpul: Fɔs, nɔs go tek blɔd sɛmpul frɔm wan vein we de na yu an. Dis go chɛk yu beslayn kɔtisol lɛvɛl bifo di tɛst bigin.
2. Gi di injεkshכn: Nεks, nכs go gi yu injεkshכn we gεt sεntetik ACTH (cosyntropin). Bɔku tɛm, dɛn kin gi dis na di mɔsul na yu an. I go tan lɛk se smɔl ant de sting yu, bɔt i go go insay sɔm sɛkɔn.
3. Sɛkɔn ɛn tɔd blɔd sɛmpul: Yu go gɛt ɔda blɔd sɛmpul 30 minit afta di injɛkshɔn. Dɔn dɛn go tek ɔda blɔd sɛmpul 60 minit afta dat . dis go mכsu aw mכch kכtisol yu adrenal gland dεm dכn prodyuz frכm di injεkshכn.
4. Fɔ sɛn to di lɛbɔraytri: Dɛn kin sɛn di blɔd sɛmpul dɛn na di lɛbɔtri.
We dɛn pul yu blɔd, yu kin jɔs fil lɛk se yu de chuk yu smɔl smɔl. Dat kin go afta sɔm tɛm. Yu kin fil smɔl brus usay dɛn pul di blɔd, ɛn dis na nɔmal tin.
Ustɛm di rizɔlt dɛn go de ɛn wetin dɛn go se?
I kin tek lɛk wan wik so fɔ mek di rizɔlt fɔ dis tɛst kam bak. Dis na bikɔs wans dɛn dɔn gɛt di rizɔlt, yu dɔktɔ go tek tɛm stɔdi dɛn ɛn kɔmpia dɛn wit di sayn dɛn we yu gɛt fɔ kam fɔ no.
Wetin na nɔmal tin we kin apin?
pan hεlty pכsin, afta di ACTH injεkshכn, di adrenal gland dεm fכ stimulate fayn fayn wan εn di kכtisol lεvεl na di bכdi fכ inkrεs bכku bכku wan. Yu dɔktɔ go ɛksplen di valyu dɛm na yu lab ripɔt ɛn di nɔmal rɛnj to yu.
Wetin na Abnɔmal Rizɔlt?
Mɛmba se na yu dɔktɔ na di bɛst pɔsin fɔ ɛksplen to yu tɛst rizɔlt. So nɔ fred fɔ tink bɔt di tin dɛn we go apin.
- Praymari Adrenal Insufficiency (if prɔblɛm de wit di adrenal gland dɛm): Insay pɔsin we gɛt dis sik, ivin if dɛn gi am ACTH injɛkshɔn, di kɔtisol lɛvɛl nɔ de go ɔp atɔl ɔ i de go ɔp bay smɔl smɔl. dis na biכs di prכblεm de na di adrenal gland dεm, εn i nכ mata aw dεn gi dεm stimulashכn frכm do, dεn nכ kin prodyuz kכtisol.
- sεkכnd Adrenal Insufisεns (if prכblεm de wit di pituitary gland): we di pituitary gland nכ de rilis ACTH fכ lכng tεm, di adrenal gland dεm de shrink sכmtεm εn bigin fכ bi inaktiv (atrophy). We dɛn gi ACTH injɛkshɔn to da kayn pɔsin de, di adrenal gland dɛn we nɔ de wok nɔ kin ebul fɔ ansa wantɛm wantɛm. fכ dat, dεn kכtisol lεvεl dεm de inkrεs sכmtεm כ nכ de inkrεs atכl.
sכmtεm, if di pituitary gland prכblεm na rili rεsεnt כ nכmכ i afekt, di kכtisol lεvεl kin εlevεt sכmtεm. Yu dɔktɔ na di bɛst pɔsin fɔ disayd bɔt ɔl dis.
Mɛsej we dɛn kin kɛr go na os
- ACTH Stimulation Test na test wae de luk aw yu adrenal gland dεm de ansa mεsej dεm frכm yu bren.
- Dɛn kin yuz dis mɔ fɔ no wan sik we dɛn kɔl adrenal insufficiency.
- Fɔ fala di dɔktɔ in instrɔkshɔn dɛn fayn fayn wan bifo yu du di tɛst (lɛk fɔ fast ɛn fɔ stɔp di mɛrɛsin).
- Dis tɛst min fɔ tek blɔd sɛmpul, gi injɛkshɔn, ɛn tek mɔ blɔd sɛmpul.
- Nɔ wɔri bɔt di tin dɛn we go apin. Yu dɔktɔ go ɛksplen dɛn kɔrɛkt wan ɛn tɛl yu bɔt di nɛks step ɛn tritmɛnt, if nid de. Nɔ fred fɔ aks yu dɔktɔ ɛni kwɛstyɔn we yu go gɛt.
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